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Items: 40

1.

MicroRNA-146a controls functional plasticity in γδ T cells by targeting NOD1.

Schmolka N, Papotto PH, Romero PV, Amado T, Enguita FJ, Amorim A, Rodrigues AF, Gordon KE, Coroadinha AS, Boldin M, Serre K, Buck AH, Gomes AQ, Silva-Santos B.

Sci Immunol. 2018 May 4;3(23). pii: eaao1392. doi: 10.1126/sciimmunol.aao1392.

PMID:
29728425
2.

miR-146a modulates autoreactive Th17 cell differentiation and regulates organ-specific autoimmunity.

Li B, Wang X, Choi IY, Wang YC, Liu S, Pham AT, Moon H, Smith DJ, Rao DS, Boldin MP, Yang L.

J Clin Invest. 2017 Oct 2;127(10):3702-3716. doi: 10.1172/JCI94012. Epub 2017 Sep 5.

3.

miR-146a-Traf6 regulatory axis controls autoimmunity and myelopoiesis, but is dispensable for hematopoietic stem cell homeostasis and tumor suppression.

Magilnick N, Reyes EY, Wang WL, Vonderfecht SL, Gohda J, Inoue JI, Boldin MP.

Proc Natl Acad Sci U S A. 2017 Aug 22;114(34):E7140-E7149. doi: 10.1073/pnas.1706833114. Epub 2017 Aug 7.

4.

miR-146b Probably Assists miRNA-146a in the Suppression of Keratinocyte Proliferation and Inflammatory Responses in Psoriasis.

Hermann H, Runnel T, Aab A, Baurecht H, Rodriguez E, Magilnick N, Urgard E, Šahmatova L, Prans E, Maslovskaja J, Abram K, Karelson M, Kaldvee B, Reemann P, Haljasorg U, Rückert B, Wawrzyniak P, Weichenthal M, Mrowietz U, Franke A, Gieger C, Barker J, Trembath R, Tsoi LC, Elder JT, Tkaczyk ER, Kisand K, Peterson P, Kingo K, Boldin M, Weidinger S, Akdis CA, Rebane A.

J Invest Dermatol. 2017 Sep;137(9):1945-1954. doi: 10.1016/j.jid.2017.05.012. Epub 2017 Jun 6.

PMID:
28595995
5.

MicroRNA-146a governs fibroblast activation and joint pathology in arthritis.

Saferding V, Puchner A, Goncalves-Alves E, Hofmann M, Bonelli M, Brunner JS, Sahin E, Niederreiter B, Hayer S, Kiener HP, Einwallner E, Nehmar R, Carapito R, Georgel P, Koenders MI, Boldin M, Schabbauer G, Kurowska-Stolarska M, Steiner G, Smolen JS, Redlich K, Blüml S.

J Autoimmun. 2017 Aug;82:74-84. doi: 10.1016/j.jaut.2017.05.006. Epub 2017 May 22.

PMID:
28545737
6.

Identification of targets of tumor suppressor microRNA-34a using a reporter library system.

Ito Y, Inoue A, Seers T, Hato Y, Igarashi A, Toyama T, Taganov KD, Boldin MP, Asahara H.

Proc Natl Acad Sci U S A. 2017 Apr 11;114(15):3927-3932. doi: 10.1073/pnas.1620019114. Epub 2017 Mar 29.

7.

Atherosclerosis-Driven Treg Plasticity Results in Formation of a Dysfunctional Subset of Plastic IFNγ+ Th1/Tregs.

Butcher MJ, Filipowicz AR, Waseem TC, McGary CM, Crow KJ, Magilnick N, Boldin M, Lundberg PS, Galkina EV.

Circ Res. 2016 Nov 11;119(11):1190-1203. doi: 10.1161/CIRCRESAHA.116.309764. Epub 2016 Sep 15.

8.

Anti-Inflammatory Role of MicroRNA-146a in the Pathogenesis of Diabetic Nephropathy.

Bhatt K, Lanting LL, Jia Y, Yadav S, Reddy MA, Magilnick N, Boldin M, Natarajan R.

J Am Soc Nephrol. 2016 Aug;27(8):2277-88. doi: 10.1681/ASN.2015010111. Epub 2015 Dec 8.

9.

Altered lymphopoiesis and immunodeficiency in miR-142 null mice.

Kramer NJ, Wang WL, Reyes EY, Kumar B, Chen CC, Ramakrishna C, Cantin EM, Vonderfecht SL, Taganov KD, Chau N, Boldin MP.

Blood. 2015 Jun 11;125(24):3720-30. doi: 10.1182/blood-2014-10-603951. Epub 2015 Apr 30.

10.

MicroRNA-146a alleviates chronic skin inflammation in atopic dermatitis through suppression of innate immune responses in keratinocytes.

Rebane A, Runnel T, Aab A, Maslovskaja J, Rückert B, Zimmermann M, Plaas M, Kärner J, Treis A, Pihlap M, Haljasorg U, Hermann H, Nagy N, Kemeny L, Erm T, Kingo K, Li M, Boldin MP, Akdis CA.

J Allergy Clin Immunol. 2014 Oct;134(4):836-847.e11. doi: 10.1016/j.jaci.2014.05.022. Epub 2014 Jul 2.

PMID:
24996260
11.

Cancer-secreted miR-105 destroys vascular endothelial barriers to promote metastasis.

Zhou W, Fong MY, Min Y, Somlo G, Liu L, Palomares MR, Yu Y, Chow A, O'Connor ST, Chin AR, Yen Y, Wang Y, Marcusson EG, Chu P, Wu J, Wu X, Li AX, Li Z, Gao H, Ren X, Boldin MP, Lin PC, Wang SE.

Cancer Cell. 2014 Apr 14;25(4):501-15. doi: 10.1016/j.ccr.2014.03.007.

12.

STAT3 induction of miR-146b forms a feedback loop to inhibit the NF-κB to IL-6 signaling axis and STAT3-driven cancer phenotypes.

Xiang M, Birkbak NJ, Vafaizadeh V, Walker SR, Yeh JE, Liu S, Kroll Y, Boldin M, Taganov K, Groner B, Richardson AL, Frank DA.

Sci Signal. 2014 Jan 28;7(310):ra11. doi: 10.1126/scisignal.2004497.

13.

miR-146a controls the resolution of T cell responses in mice.

Yang L, Boldin MP, Yu Y, Liu CS, Ea CK, Ramakrishnan P, Taganov KD, Zhao JL, Baltimore D.

J Exp Med. 2012 Aug 27;209(9):1655-70. doi: 10.1084/jem.20112218. Epub 2012 Aug 13.

14.

Regulation of APC development, immune response, and autoimmunity by Bach1/HO-1 pathway in mice.

So AY, Garcia-Flores Y, Minisandram A, Martin A, Taganov K, Boldin M, Baltimore D.

Blood. 2012 Sep 20;120(12):2428-37. Epub 2012 Jul 12.

15.

MicroRNAs, new effectors and regulators of NF-κB.

Boldin MP, Baltimore D.

Immunol Rev. 2012 Mar;246(1):205-20. doi: 10.1111/j.1600-065X.2011.01089.x. Review.

PMID:
22435557
16.

NF-kappaB dysregulation in microRNA-146a-deficient mice drives the development of myeloid malignancies.

Zhao JL, Rao DS, Boldin MP, Taganov KD, O'Connell RM, Baltimore D.

Proc Natl Acad Sci U S A. 2011 May 31;108(22):9184-9. doi: 10.1073/pnas.1105398108. Epub 2011 May 16.

17.

miR-146a is a significant brake on autoimmunity, myeloproliferation, and cancer in mice.

Boldin MP, Taganov KD, Rao DS, Yang L, Zhao JL, Kalwani M, Garcia-Flores Y, Luong M, Devrekanli A, Xu J, Sun G, Tay J, Linsley PS, Baltimore D.

J Exp Med. 2011 Jun 6;208(6):1189-201. doi: 10.1084/jem.20101823. Epub 2011 May 9.

18.

Function of miR-146a in controlling Treg cell-mediated regulation of Th1 responses.

Lu LF, Boldin MP, Chaudhry A, Lin LL, Taganov KD, Hanada T, Yoshimura A, Baltimore D, Rudensky AY.

Cell. 2010 Sep 17;142(6):914-29. doi: 10.1016/j.cell.2010.08.012.

19.

Encoding NF-kappaB temporal control in response to TNF: distinct roles for the negative regulators IkappaBalpha and A20.

Werner SL, Kearns JD, Zadorozhnaya V, Lynch C, O'Dea E, Boldin MP, Ma A, Baltimore D, Hoffmann A.

Genes Dev. 2008 Aug 1;22(15):2093-101. doi: 10.1101/gad.1680708.

20.

MicroRNAs: new regulators of immune cell development and function.

Baltimore D, Boldin MP, O'Connell RM, Rao DS, Taganov KD.

Nat Immunol. 2008 Aug;9(8):839-45. doi: 10.1038/ni.f.209. Review.

PMID:
18645592
21.

Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder.

O'Connell RM, Rao DS, Chaudhuri AA, Boldin MP, Taganov KD, Nicoll J, Paquette RL, Baltimore D.

J Exp Med. 2008 Mar 17;205(3):585-94. doi: 10.1084/jem.20072108. Epub 2008 Feb 25.

22.

MicroRNAs and immunity: tiny players in a big field.

Taganov KD, Boldin MP, Baltimore D.

Immunity. 2007 Feb;26(2):133-7. Review.

23.

MicroRNA-155 is induced during the macrophage inflammatory response.

O'Connell RM, Taganov KD, Boldin MP, Cheng G, Baltimore D.

Proc Natl Acad Sci U S A. 2007 Jan 30;104(5):1604-9. Epub 2007 Jan 22.

24.

NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses.

Taganov KD, Boldin MP, Chang KJ, Baltimore D.

Proc Natl Acad Sci U S A. 2006 Aug 15;103(33):12481-6. Epub 2006 Aug 2.

25.

How are the regulators regulated? The search for mechanisms that impose specificity on induction of cell death and NF-kappaB activation by members of the TNF/NGF receptor family.

Wallach D, Arumugam TU, Boldin MP, Cantarella G, Ganesh KA, Goltsev Y, Goncharov TM, Kovalenko AV, Rajput A, Varfolomeev EE, Zhang SQ.

Arthritis Res. 2002;4 Suppl 3:S189-96. Epub 2002 May 9. Review.

26.

Tumor necrosis factor receptor and Fas signaling mechanisms.

Wallach D, Varfolomeev EE, Malinin NL, Goltsev YV, Kovalenko AV, Boldin MP.

Annu Rev Immunol. 1999;17:331-67. Review.

PMID:
10358762
27.

Death-inducing functions of ligands of the tumor necrosis factor family: a Sanhedrin verdict.

Wallach D, Kovalenko AV, Varfolomeev EE, Boldin MP.

Curr Opin Immunol. 1998 Jun;10(3):279-88. Review.

PMID:
9638364
28.

The yeast two-hybrid screening technique and its use in the study of protein-protein interactions in apoptosis.

Wallach D, Boldin MP, Kovalenko AV, Malinin NL, Mett IL, Camonis JH.

Curr Opin Immunol. 1998 Apr;10(2):131-6. Review.

PMID:
9602300
30.

Cell death induction by receptors of the TNF family: towards a molecular understanding.

Wallach D, Boldin M, Varfolomeev E, Beyaert R, Vandenabeele P, Fiers W.

FEBS Lett. 1997 Jun 23;410(1):96-106. Review. No abstract available.

31.

MAP3K-related kinase involved in NF-kappaB induction by TNF, CD95 and IL-1.

Malinin NL, Boldin MP, Kovalenko AV, Wallach D.

Nature. 1997 Feb 6;385(6616):540-4.

PMID:
9020361
32.

Exploring cell death mechanisms by analyzing signaling cascades of the TNF/NGF receptor family.

Wallach D, Boldin M, Goncharov T, Goltsev Y, Mett I, Malinin N, Adar R, Kovalenko A, Varfolomeev E.

Behring Inst Mitt. 1996 Oct;(97):144-55. Review.

PMID:
8950472
33.
35.

The death domain: a module shared by proteins with diverse cellular functions.

Feinstein E, Kimchi A, Wallach D, Boldin M, Varfolomeev E.

Trends Biochem Sci. 1995 Sep;20(9):342-4. No abstract available.

PMID:
7482697
37.

A novel protein that interacts with the death domain of Fas/APO1 contains a sequence motif related to the death domain.

Boldin MP, Varfolomeev EE, Pancer Z, Mett IL, Camonis JH, Wallach D.

J Biol Chem. 1995 Apr 7;270(14):7795-8.

38.

Self-association of the "death domains" of the p55 tumor necrosis factor (TNF) receptor and Fas/APO1 prompts signaling for TNF and Fas/APO1 effects.

Boldin MP, Mett IL, Varfolomeev EE, Chumakov I, Shemer-Avni Y, Camonis JH, Wallach D.

J Biol Chem. 1995 Jan 6;270(1):387-91.

39.

A controlled trial of rifampicin, minocycline, and rifampicin plus minocycline for eradication of methicillin-resistant Staphylococcus aureus in long-term care patients.

Muder RR, Boldin M, Brennen C, Hsieh M, Vickers RM, Mitchum K, Yee YC.

J Antimicrob Chemother. 1994 Jul;34(1):189-90. No abstract available.

PMID:
7961212
40.

Controlled evaluation of copper-silver ionization in eradicating Legionella pneumophila from a hospital water distribution system.

Liu Z, Stout JE, Tedesco L, Boldin M, Hwang C, Diven WF, Yu VL.

J Infect Dis. 1994 Apr;169(4):919-22.

PMID:
8133111

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