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Items: 1 to 50 of 682

1.

Immune checkpoints PVR and PVRL2 are prognostic markers in AML and their blockade represents a new therapeutic option.

Stamm H, Klingler F, Grossjohann EM, Muschhammer J, Vettorazzi E, Heuser M, Mock U, Thol F, Vohwinkel G, Latuske E, Bokemeyer C, Kischel R, Dos Santos C, Stienen S, Friedrich M, Lutteropp M, Nagorsen D, Wellbrock J, Fiedler W.

Oncogene. 2018 May 31. doi: 10.1038/s41388-018-0288-y. [Epub ahead of print]

PMID:
29855615
2.

Synthesis and anticancer activity of the derivatives of marine compound rhizochalin in castration resistant prostate cancer.

Dyshlovoy SA, Otte K, Tabakmakher KM, Hauschild J, Makarieva TN, Shubina LK, Fedorov SN, Bokemeyer C, Stonik VA, von Amsberg G.

Oncotarget. 2018 Mar 30;9(24):16962-16973. doi: 10.18632/oncotarget.24764. eCollection 2018 Mar 30.

3.

Blockade of Myeloid-Derived Suppressor Cell Expansion with All-Trans Retinoic Acid Increases the Efficacy of Antiangiogenic Therapy.

Bauer R, Udonta F, Wroblewski M, Ben-Batalla I, Santos IM, Taverna F, Kuhlencord M, Gensch V, Päsler S, Vinckier S, Brandner JM, Pantel K, Bokemeyer C, Vogl T, Roth J, Carmeliet P, Loges S.

Cancer Res. 2018 Jun 15;78(12):3220-3232. doi: 10.1158/0008-5472.CAN-17-3415. Epub 2018 Apr 19.

PMID:
29674477
4.

Dynamic changes of the normal B lymphocyte repertoire in CLL in response to ibrutinib or FCR chemo-immunotherapy.

Schliffke S, Sivina M, Kim E, von Wenserski L, Thiele B, Akyüz N, Falker-Gieske C, Statovci D, Oberle A, Thenhausen T, Krohn-Grimberghe A, Bokemeyer C, Jain N, Estrov Z, Ferrajoli A, Wierda W, Keating M, Burger JA, Binder M.

Oncoimmunology. 2018 Jan 15;7(4):e1417720. doi: 10.1080/2162402X.2017.1417720. eCollection 2018.

PMID:
29632735
5.

Evaluation of a program for routine implementation of shared decision-making in cancer care: study protocol of a stepped wedge cluster randomized trial.

Scholl I, Hahlweg P, Lindig A, Bokemeyer C, Coym A, Hanken H, Müller V, Smeets R, Witzel I, Kriston L, Härter M.

Implement Sci. 2018 Mar 27;13(1):51. doi: 10.1186/s13012-018-0740-y.

6.

BET-inhibition by JQ1 promotes proliferation and self-renewal capacity of hematopoietic stem cells.

Wroblewski M, Scheller-Wendorff M, Udonta F, Bauer R, Schlichting J, Zhao L, Ben Batalla I, Gensch V, Päsler S, Wu L, Wanior M, Taipaleenmäki H, Bolamperti S, Najafova Z, Pantel K, Bokemeyer C, Qi J, Hesse E, Knapp S, Johnsen S, Loges S.

Haematologica. 2018 Jun;103(6):939-948. doi: 10.3324/haematol.2017.181354. Epub 2018 Mar 22.

7.

BCL2-overexpressing prostate cancer cells rely on PARP1-dependent end-joining and are sensitive to combined PARP inhibitor and radiation therapy.

Oing C, Tennstedt P, Simon R, Volquardsen J, Borgmann K, Bokemeyer C, Petersen C, Dikomey E, Rothkamm K, Mansour WY.

Cancer Lett. 2018 Jun 1;423:60-70. doi: 10.1016/j.canlet.2018.03.007. Epub 2018 Mar 8.

PMID:
29526801
8.

Therapeutic approaches for refractory germ cell cancer.

Oing C, Seidel C, Bokemeyer C.

Expert Rev Anticancer Ther. 2018 Apr;18(4):389-397. doi: 10.1080/14737140.2018.1450630. Epub 2018 Mar 12.

PMID:
29516750
9.

Intermediate prognosis in metastatic germ cell tumours-outcome and prognostic factors.

Seidel C, Daugaard G, Tryakin A, Necchi A, Cohn Cedermark G, Ståhl O, Hentrich M, Brito M, Albany C, Taza F, Gerl A, Oechsle K, Bokemeyer C.

Eur J Cancer. 2018 May;94:16-25. doi: 10.1016/j.ejca.2018.01.113. Epub 2018 Mar 20.

PMID:
29505967
10.

Management of anaemia and iron deficiency in patients with cancer: ESMO Clinical Practice Guidelines.

Aapro M, Beguin Y, Bokemeyer C, Dicato M, Gascón P, Glaspy J, Hofmann A, Link H, Littlewood T, Ludwig H, Österborg A, Pronzato P, Santini V, Schrijvers D, Stauder R, Jordan K, Herrstedt J; ESMO Guidelines Committee.

Ann Oncol. 2018 Feb 20. doi: 10.1093/annonc/mdx758. [Epub ahead of print] No abstract available.

PMID:
29471514
11.

Treatment of Metastatic Spindle Epithelial Tumor with Thymus-Like Differentiation (SETTLE) - Long-Term Disease Control by Multimodal Therapy.

Quidde J, Alsdorf WH, von Amsberg G, Wilczak W, Bokemeyer C.

Oncol Res Treat. 2018;41(1-2):58-60. doi: 10.1159/000480017. Epub 2018 Jan 22.

PMID:
29402817
12.

Personalizing Survival Predictions in Advanced Colorectal Cancer: The ARCAD Nomogram Project.

Sjoquist KM, Renfro LA, Simes RJ, Tebbutt NC, Clarke S, Seymour MT, Adams R, Maughan TS, Saltz L, Goldberg RM, Schmoll HJ, Van Cutsem E, Douillard JY, Hoff PM, Hecht JR, Tournigand C, Punt CJA, Koopman M, Hurwitz H, Heinemann V, Falcone A, Porschen R, Fuchs C, Diaz-Rubio E, Aranda E, Bokemeyer C, Souglakos I, Kabbinavar FF, Chibaudel B, Meyers JP, Sargent DJ, de Gramont A, Zalcberg JR; Fondation Aide et Recherche en Cancerologie Digestive Group.

J Natl Cancer Inst. 2017 Dec 18. doi: 10.1093/jnci/djx253. [Epub ahead of print]

PMID:
29267900
13.

Testicular Tumour Size and Rete Testis Invasion as Prognostic Factors for the Risk of Relapse of Clinical Stage I Seminoma Testis Patients Under Surveillance: a Systematic Review by the Testicular Cancer Guidelines Panel.

Boormans JL, Mayor de Castro J, Marconi L, Yuan Y, Laguna Pes MP, Bokemeyer C, Nicolai N, Algaba F, Oldenburg J, Albers P.

Eur Urol. 2017 Nov 20. pii: S0302-2838(17)30826-6. doi: 10.1016/j.eururo.2017.09.025. [Epub ahead of print] Review.

PMID:
29100813
14.

Specific Characteristics of Patients with Advanced Genitourinary Cancer Receiving Specialized Inpatient Palliative Care.

Iversen K, Oechsle K, Oing C, Bokemeyer C, Seidel C.

Oncol Res Treat. 2017;40(10):609-614. doi: 10.1159/000478934. Epub 2017 Sep 19.

PMID:
28950274
15.

Mast cells decrease efficacy of anti-angiogenic therapy by secreting matrix-degrading granzyme B.

Wroblewski M, Bauer R, Cubas Córdova M, Udonta F, Ben-Batalla I, Legler K, Hauser C, Egberts J, Janning M, Velthaus J, Schulze C, Pantel K, Bokemeyer C, Loges S.

Nat Commun. 2017 Aug 16;8(1):269. doi: 10.1038/s41467-017-00327-8.

16.

The impact of bleeding disorders on the socioeconomic status of adult patients. Results of a comparative single centre cohort study.

Holstein K, von Mackensen S, Bokemeyer C, Langer F.

Hamostaseologie. 2017 Jul 10;99(99). doi: 10.5482/HAMO-16-12-0047. [Epub ahead of print]

PMID:
28692112
17.

[New Aspects in Treatment of Metastatic Prostate Cancer].

von Amsberg G, Bokemeyer C.

Dtsch Med Wochenschr. 2017 Aug;142(15):1106-1110. doi: 10.1055/s-0043-105768. Epub 2017 Jun 23. German.

PMID:
28645133
18.

Long-term CD38 saturation by daratumumab interferes with diagnostic myeloma cell detection.

Oberle A, Brandt A, Alawi M, Langebrake C, Janjetovic S, Wolschke C, Schütze K, Bannas P, Kröger N, Koch-Nolte F, Bokemeyer C, Binder M.

Haematologica. 2017 Sep;102(9):e368-e370. doi: 10.3324/haematol.2017.169235. Epub 2017 May 18. No abstract available.

19.

Testis cancer: some problems still remain unsolved.

Albers P, Bokemeyer C.

World J Urol. 2017 Aug;35(8):1159-1160. doi: 10.1007/s00345-017-2041-5. Epub 2017 May 16. No abstract available.

PMID:
28509970
20.

Frondoside A induces AIF-associated caspase-independent apoptosis in Burkitt lymphoma cells.

Dyshlovoy SA, Rast S, Hauschild J, Otte K, Alsdorf WH, Madanchi R, Kalinin VI, Silchenko AS, Avilov SA, Dierlamm J, Honecker F, Stonik VA, Bokemeyer C, von Amsberg G.

Leuk Lymphoma. 2017 Dec;58(12):2905-2915. doi: 10.1080/10428194.2017.1317091. Epub 2017 May 16.

PMID:
28508718
21.

Quality of life, psychological burden, needs, and satisfaction during specialized inpatient palliative care in family caregivers of advanced cancer patients.

Ullrich A, Ascherfeld L, Marx G, Bokemeyer C, Bergelt C, Oechsle K.

BMC Palliat Care. 2017 May 10;16(1):31. doi: 10.1186/s12904-017-0206-z.

22.

Exploratory analysis of the neutrophil to lymphocyte ratio in patients with pulmonary arterial hypertension.

Harbaum L, Baaske KM, Simon M, Oqueka T, Sinning C, Glatzel A, Lüneburg N, Sydow K, Bokemeyer C, Klose H.

BMC Pulm Med. 2017 Apr 26;17(1):72. doi: 10.1186/s12890-017-0407-5.

23.

Proteomic-based investigations on the mode of action of the marine anticancer compound rhizochalinin.

Dyshlovoy SA, Otte K, Venz S, Hauschild J, Junker H, Makarieva TN, Balabanov S, Alsdorf WH, Madanchi R, Honecker F, Bokemeyer C, Stonik VA, von Amsberg G.

Proteomics. 2017 Jun;17(11). doi: 10.1002/pmic.201700048.

PMID:
28445005
24.

Combined inhibition of GLI and FLT3 signaling leads to effective anti-leukemic effects in human acute myeloid leukemia.

Latuske EM, Stamm H, Klokow M, Vohwinkel G, Muschhammer J, Bokemeyer C, Jücker M, Kebenko M, Fiedler W, Wellbrock J.

Oncotarget. 2017 Apr 25;8(17):29187-29201. doi: 10.18632/oncotarget.16304.

25.

Clinical Calculator for Early Mortality in Metastatic Colorectal Cancer: An Analysis of Patients From 28 Clinical Trials in the Aide et Recherche en Cancérologie Digestive Database.

Renfro LA, Goldberg RM, Grothey A, Sobrero A, Adams R, Seymour MT, Heinemann V, Schmoll HJ, Douillard JY, Hurwitz H, Fuchs CS, Diaz-Rubio E, Porschen R, Tournigand C, Chibaudel B, Hoff PM, Kabbinavar FF, Falcone A, Tebbutt NC, Punt CJA, Hecht JR, Souglakos J, Bokemeyer C, Van Cutsem E, Saltz L, de Gramont A, Sargent DJ; ARCAD Clinical Trials Program.

J Clin Oncol. 2017 Jun 10;35(17):1929-1937. doi: 10.1200/JCO.2016.71.5771. Epub 2017 Apr 17.

26.

Autologous Stem Cell Transplantation in Multiple Myeloma in the Era of Novel Drug Induction: A Retrospective Single-Center Analysis.

Thoennissen GB, Görlich D, Bacher U, Aufenberg T, Hüsken AC, Hansmeier AA, Evers G, Mikesch JH, Fritz F, Bokemeyer C, Müller-Tidow C, Stelljes M, Mesters RM, Krug U, Kropff MH, Thoennissen NH, Berdel WE.

Acta Haematol. 2017;137(3):163-172. doi: 10.1159/000463534. Epub 2017 Apr 12.

27.

Retinal toxicity after cisplatin-based chemotherapy in patients with germ cell cancer.

Dulz S, Asselborn NH, Dieckmann KP, Matthies C, Wagner W, Weidmann J, Seidel C, Oing C, Berger LA, Alsdorf W, Mankichian B, Meyer C, Vetterlein MW, Gild P, Ludwig TA, Soave A, Schriefer P, Becker A, Ahyai SA, Oechsle K, Bokemeyer C, Wagenfeld L, Fisch M, Hartmann M, Chun FK, Kluth LA.

J Cancer Res Clin Oncol. 2017 Jul;143(7):1319-1325. doi: 10.1007/s00432-017-2384-8. Epub 2017 Mar 9.

PMID:
28281024
28.

MALT1 sequencing analyses in marginal zone B-cell lymphomas reveal mutations in the translocated MALT1 allele in an IGH-MALT1-positive MALT lymphoma.

Akyüz N, Albert-Konetzny N, Pott C, Callet-Bauchu E, Bokemeyer C, Murga Penas EM, Dierlamm J.

Leuk Lymphoma. 2017 Oct;58(10):2480-2484. doi: 10.1080/10428194.2017.1296144. Epub 2017 Mar 2. No abstract available.

PMID:
28278699
29.

Mutational landscape reflects the biological continuum of plasma cell dyscrasias.

Rossi A, Voigtlaender M, Janjetovic S, Thiele B, Alawi M, März M, Brandt A, Hansen T, Radloff J, Schön G, Hegenbart U, Schönland S, Langer C, Bokemeyer C, Binder M.

Blood Cancer J. 2017 Feb 24;7(2):e537. doi: 10.1038/bcj.2017.19.

30.

Corrigendum re: "Serum Levels of MicroRNA miR-371a-3p: A Sensitive and Specific New Biomarker for Germ Cell Tumours" [Eur Urol 2017;71:213-20].

Dieckmann KP, Radtke A, Spiekermann M, Balks T, Matthies C, Becker P, Ruf C, Oing C, Oechsle K, Bokemeyer C, Hammel J, Melchior S, Wosniok W, Belge G.

Eur Urol. 2017 May;71(5):e161. doi: 10.1016/j.eururo.2017.01.041. Epub 2017 Feb 13. No abstract available.

PMID:
28209431
31.

The marine triterpene glycoside frondoside A induces p53-independent apoptosis and inhibits autophagy in urothelial carcinoma cells.

Dyshlovoy SA, Madanchi R, Hauschild J, Otte K, Alsdorf WH, Schumacher U, Kalinin VI, Silchenko AS, Avilov SA, Honecker F, Stonik VA, Bokemeyer C, von Amsberg G.

BMC Cancer. 2017 Feb 1;17(1):93. doi: 10.1186/s12885-017-3085-z.

32.

Over- and under-prophylaxis for chemotherapy-induced (febrile) neutropenia relative to evidence-based guidelines is associated with differences in outcomes: findings from the MONITOR-GCSF study.

Bokemeyer C, Gascón P, Aapro M, Ludwig H, Boccadoro M, Denhaerynck K, Gorray M, Krendyukov A, Abraham I, MacDonald K.

Support Care Cancer. 2017 Jun;25(6):1819-1828. doi: 10.1007/s00520-017-3572-4. Epub 2017 Jan 22.

33.

Cetuximab Resistance in Head and Neck Cancer Is Mediated by EGFR-K521 Polymorphism.

Braig F, Kriegs M, Voigtlaender M, Habel B, Grob T, Biskup K, Blanchard V, Sack M, Thalhammer A, Ben Batalla I, Braren I, Laban S, Danielczyk A, Goletz S, Jakubowicz E, Märkl B, Trepel M, Knecht R, Riecken K, Fehse B, Loges S, Bokemeyer C, Binder M.

Cancer Res. 2017 Mar 1;77(5):1188-1199. doi: 10.1158/0008-5472.CAN-16-0754. Epub 2016 Dec 28.

34.

Impact of primary metastatic bone disease in germ cell tumors: results of an International Global Germ Cell Tumor Collaborative Group G3 Registry Study.

Oing C, Oechsle K, Necchi A, Loriot Y, De Giorgi U, Fléchon A, Daugaard G, Fedyanin M, Faré E, Bokemeyer C.

Ann Oncol. 2017 Mar 1;28(3):576-582. doi: 10.1093/annonc/mdw648.

PMID:
27993806
35.

T-cell diversification reflects antigen selection in the blood of patients on immune checkpoint inhibition and may be exploited as liquid biopsy biomarker.

Akyüz N, Brandt A, Stein A, Schliffke S, Mährle T, Quidde J, Goekkurt E, Loges S, Haalck T, Ford CT, Asemissen AM, Thiele B, Radloff J, Thenhausen T, Krohn-Grimberghe A, Bokemeyer C, Binder M.

Int J Cancer. 2017 Jun 1;140(11):2535-2544. doi: 10.1002/ijc.30549. Epub 2017 Mar 6.

36.

Axl Blockade by BGB324 Inhibits BCR-ABL Tyrosine Kinase Inhibitor-Sensitive and -Resistant Chronic Myeloid Leukemia.

Ben-Batalla I, Erdmann R, Jørgensen H, Mitchell R, Ernst T, von Amsberg G, Schafhausen P, Velthaus JL, Rankin S, Clark RE, Koschmieder S, Schultze A, Mitra S, Vandenberghe P, Brümmendorf TH, Carmeliet P, Hochhaus A, Pantel K, Bokemeyer C, Helgason GV, Holyoake TL, Loges S.

Clin Cancer Res. 2017 May 1;23(9):2289-2300. doi: 10.1158/1078-0432.CCR-16-1930. Epub 2016 Nov 17.

37.

Acute effects of exercise on the inflammatory state in patients with idiopathic pulmonary arterial hypertension.

Harbaum L, Renk E, Yousef S, Glatzel A, Lüneburg N, Hennigs JK, Oqueka T, Baumann HJ, Atanackovic D, Grünig E, Böger RH, Bokemeyer C, Klose H.

BMC Pulm Med. 2016 Nov 11;16(1):145.

38.

Chemotherapy-induced (febrile) neutropenia prophylaxis with biosimilar filgrastim in elderly versus non-elderly cancer patients: Patterns, outcomes, and determinants (MONITOR-GCSF study).

Aapro M, Bokemeyer C, Ludwig H, Gascón P, Boccadoro M, Denhaerynck K, Gorray M, Krendyukov A, MacDonald K, Abraham I.

J Geriatr Oncol. 2017 Mar;8(2):86-95. doi: 10.1016/j.jgo.2016.09.006. Epub 2016 Nov 6.

39.

Improved nutrition in adolescents and young adults after childhood cancer - INAYA study.

Quidde J, von Grundherr J, Koch B, Bokemeyer C, Escherich G, Valentini L, Buchholz D, Schilling G, Stein A.

BMC Cancer. 2016 Nov 8;16(1):872.

40.

Clinical response to ibrutinib is accompanied by normalization of the T-cell environment in CLL-related autoimmune cytopenia.

Schliffke S, Akyüz N, Ford CT, Mährle T, Thenhausen T, Krohn-Grimberghe A, Knop S, Bokemeyer C, Binder M.

Leukemia. 2016 Nov;30(11):2232-2234. doi: 10.1038/leu.2016.157. Epub 2016 May 25. No abstract available.

PMID:
27220665
41.

Predictive modeling of the outcomes of chemotherapy-induced (febrile) neutropenia prophylaxis with biosimilar filgrastim (MONITOR-GCSF study).

Aapro M, Ludwig H, Bokemeyer C, Gascón P, Boccadoro M, Denhaerynck K, Krendyukov A, Gorray M, MacDonald K, Abraham I.

Ann Oncol. 2016 Nov;27(11):2039-2045.

42.

Expression and release of platelet protein disulphide isomerase in patients with haemophilia A.

Voigtlaender M, Holstein K, Spath B, Bokemeyer C, Langer F.

Haemophilia. 2016 Nov;22(6):e537-e544. doi: 10.1111/hae.13074. Epub 2016 Oct 20.

PMID:
27761968
43.

[Vorwort].

Bokemeyer C, Hallek M, Lüftner D, Weißinger F.

Oncol Res Treat. 2016;39 Suppl 2:1. Epub 2016 Aug 31. German. No abstract available.

44.

Corrigendum to 'Microvesicle-associated tissue factor procoagulant activity for the preoperative diagnosis of ovarian cancer", [Thromb. Res. 141 (2016) 39-48].

Claussen C, Rausch AV, Lezius S, Amirkhosravi A, Davila M, Francis JL, Hisada YM, Mackman N, Bokemeyer C, Schmalfeldt B, Mahner S, Langer F.

Thromb Res. 2016 Oct;146:135. doi: 10.1016/j.thromres.2016.09.008. Epub 2016 Sep 16. No abstract available.

PMID:
27640329
45.

Marine compound rhizochalinin shows high in vitro and in vivo efficacy in castration resistant prostate cancer.

Dyshlovoy SA, Otte K, Alsdorf WH, Hauschild J, Lange T, Venz S, Bauer CK, Bähring R, Amann K, Mandanchi R, Schumacher U, Schröder-Schwarz J, Makarieva TN, Guzii AG, Tabakmakher KM, Fedorov SN, Shubina LK, Kasheverov IE, Ehmke H, Steuber T, Stonik VA, Bokemeyer C, Honecker F, von Amsberg G.

Oncotarget. 2016 Oct 25;7(43):69703-69717. doi: 10.18632/oncotarget.11941.

46.

Serum Levels of MicroRNA miR-371a-3p: A Sensitive and Specific New Biomarker for Germ Cell Tumours.

Dieckmann KP, Radtke A, Spiekermann M, Balks T, Matthies C, Becker P, Ruf C, Oing C, Oechsle K, Bokemeyer C, Hammel J, Melchior S, Wosniok W, Belge G.

Eur Urol. 2017 Feb;71(2):213-220. doi: 10.1016/j.eururo.2016.07.029. Epub 2016 Aug 2. Erratum in: Eur Urol. 2017 May;71(5):e161.

47.

Platinum-refractory germ cell tumors: an update on current treatment options and developments.

Oing C, Alsdorf WH, von Amsberg G, Oechsle K, Bokemeyer C.

World J Urol. 2017 Aug;35(8):1167-1175. doi: 10.1007/s00345-016-1898-z. Epub 2016 Jul 23. Review.

PMID:
27449639
48.

Guanidine Alkaloids from the Marine Sponge Monanchora pulchra Show Cytotoxic Properties and Prevent EGF-Induced Neoplastic Transformation in Vitro.

Dyshlovoy SA, Tabakmakher KM, Hauschild J, Shchekaleva RK, Otte K, Guzii AG, Makarieva TN, Kudryashova EK, Fedorov SN, Shubina LK, Bokemeyer C, Honecker F, Stonik VA, von Amsberg G.

Mar Drugs. 2016 Jul 15;14(7). pii: E133. doi: 10.3390/md14070133.

49.

Cabazitaxel overcomes cisplatin resistance in germ cell tumour cells.

Gerwing M, Jacobsen C, Dyshlovoy S, Hauschild J, Rohlfing T, Oing C, Venz S, Oldenburg J, Oechsle K, Bokemeyer C, von Amsberg G, Honecker F.

J Cancer Res Clin Oncol. 2016 Sep;142(9):1979-94. doi: 10.1007/s00432-016-2204-6. Epub 2016 Jul 16.

PMID:
27424191
50.

Pretrichodermamides D-F from a Marine Algicolous Fungus Penicillium sp. KMM 4672.

Yurchenko AN, Smetanina OF, Ivanets EV, Kalinovsky AI, Khudyakova YV, Kirichuk NN, Popov RS, Bokemeyer C, von Amsberg G, Chingizova EA, Afiyatullov SSh, Dyshlovoy SA.

Mar Drugs. 2016 Jun 27;14(7). pii: E122. doi: 10.3390/md14070122.

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