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Items: 32

1.

A Polymer-Based Antibody-Vinca Drug Conjugate Platform: Characterization and Preclinical Efficacy.

Yurkovetskiy AV, Yin M, Bodyak N, Stevenson CA, Thomas JD, Hammond CE, Qin L, Zhu B, Gumerov DR, Ter-Ovanesyan E, Uttard A, Lowinger TB.

Cancer Res. 2015 Aug 15;75(16):3365-72. doi: 10.1158/0008-5472.CAN-15-0129. Epub 2015 Jun 25.

2.

Mitochondrial DNA deletions in mice in men: substantia nigra is much less affected in the mouse.

Guo X, Kudryavtseva E, Bodyak N, Nicholas A, Dombrovsky I, Yang D, Kraytsberg Y, Simon DK, Khrapko K.

Biochim Biophys Acta. 2010 Jun-Jul;1797(6-7):1159-62. doi: 10.1016/j.bbabio.2010.04.005. Epub 2010 Apr 11.

3.

Pharmacological inhibition of the hypertensive response to combretastatin A-4 phosphate in rats.

Ke Q, Bodyak N, Rigor DL, Hurst NW, Chaplin DJ, Kang PM.

Vascul Pharmacol. 2009 Nov-Dec;51(5-6):337-43. doi: 10.1016/j.vph.2009.08.004. Epub 2009 Sep 6.

PMID:
19737629
4.

Quantitative analysis of somatic mitochondrial DNA mutations by single-cell single-molecule PCR.

Kraytsberg Y, Bodyak N, Myerow S, Nicholas A, Ebralidze K, Khrapko K.

Methods Mol Biol. 2009;554:329-69. doi: 10.1007/978-1-59745-521-3_21.

PMID:
19513684
5.

Collection of isolated cells for studying mitochondrial DNA mutations within individual cells.

Kraytsberg Y, Bodyak N, Myerow S, Nicholas A, Ebralidze K, Khrapko K.

Methods Mol Biol. 2009;554:315-27. doi: 10.1007/978-1-59745-521-3_20.

PMID:
19513683
6.

Renal and cardiac endothelial heterogeneity impact acute vascular rejection in pig-to-baboon xenotransplantation.

Knosalla C, Yazawa K, Behdad A, Bodyak N, Shang H, B├╝hler L, Houser S, Gollackner B, Griesemer A, Schmitt-Knosalla I, Schuurman HJ, Awwad M, Sachs DH, Cooper DK, Yamada K, Usheva A, Robson SC.

Am J Transplant. 2009 May;9(5):1006-16. doi: 10.1111/j.1600-6143.2009.02602.x.

7.

MicroRNA-1 negatively regulates expression of the hypertrophy-associated calmodulin and Mef2a genes.

Ikeda S, He A, Kong SW, Lu J, Bejar R, Bodyak N, Lee KH, Ma Q, Kang PM, Golub TR, Pu WT.

Mol Cell Biol. 2009 Apr;29(8):2193-204. doi: 10.1128/MCB.01222-08. Epub 2009 Feb 2.

8.

Phosphoinositide 3-kinase Akt signaling pathway interacts with protein kinase Cbeta2 in the regulation of physiologic developmental hypertrophy and heart function.

Rigor DL, Bodyak N, Bae S, Choi JH, Zhang L, Ter-Ovanesyan D, He Z, McMullen JR, Shioi T, Izumo S, King GL, Kang PM.

Am J Physiol Heart Circ Physiol. 2009 Mar;296(3):H566-72. doi: 10.1152/ajpheart.00562.2008. Epub 2009 Jan 2.

9.

Elevated levels of placental growth factor represent an adaptive host response in sepsis.

Yano K, Okada Y, Beldi G, Shih SC, Bodyak N, Okada H, Kang PM, Luscinskas W, Robson SC, Carmeliet P, Karumanchi SA, Aird WC.

J Exp Med. 2008 Oct 27;205(11):2623-31. doi: 10.1084/jem.20080398. Epub 2008 Oct 13.

10.

Deletion of Ptpn11 (Shp2) in cardiomyocytes causes dilated cardiomyopathy via effects on the extracellular signal-regulated kinase/mitogen-activated protein kinase and RhoA signaling pathways.

Kontaridis MI, Yang W, Bence KK, Cullen D, Wang B, Bodyak N, Ke Q, Hinek A, Kang PM, Liao R, Neel BG.

Circulation. 2008 Mar 18;117(11):1423-35. doi: 10.1161/CIRCULATIONAHA.107.728865. Epub 2008 Mar 3. Erratum in: Circulation.2008 Apr 15;117(15) e314.

11.

Activated vitamin D attenuates left ventricular abnormalities induced by dietary sodium in Dahl salt-sensitive animals.

Bodyak N, Ayus JC, Achinger S, Shivalingappa V, Ke Q, Chen YS, Rigor DL, Stillman I, Tamez H, Kroeger PE, Wu-Wong RR, Karumanchi SA, Thadhani R, Kang PM.

Proc Natl Acad Sci U S A. 2007 Oct 23;104(43):16810-5. Epub 2007 Oct 17.

12.

Uncoupling protein 2 modulates cell viability in adult rat cardiomyocytes.

Bodyak N, Rigor DL, Chen YS, Han Y, Bisping E, Pu WT, Kang PM.

Am J Physiol Heart Circ Physiol. 2007 Jul;293(1):H829-35. Epub 2007 Apr 27.

13.

Response of caspase-independent apoptotic factors to high salt diet-induced heart failure.

Siu PM, Bae S, Bodyak N, Rigor DL, Kang PM.

J Mol Cell Cardiol. 2007 Mar;42(3):678-86. Epub 2007 Jan 9.

14.

Gata4 is required for maintenance of postnatal cardiac function and protection from pressure overload-induced heart failure.

Bisping E, Ikeda S, Kong SW, Tarnavski O, Bodyak N, McMullen JR, Rajagopal S, Son JK, Ma Q, Springer Z, Kang PM, Izumo S, Pu WT.

Proc Natl Acad Sci U S A. 2006 Sep 26;103(39):14471-6. Epub 2006 Sep 18.

15.

Overexpression of HAX-1 protects cardiac myocytes from apoptosis through caspase-9 inhibition.

Han Y, Chen YS, Liu Z, Bodyak N, Rigor D, Bisping E, Pu WT, Kang PM.

Circ Res. 2006 Aug 18;99(4):415-23. Epub 2006 Jul 20.

16.

Vascular endothelial growth factor is an important determinant of sepsis morbidity and mortality.

Yano K, Liaw PC, Mullington JM, Shih SC, Okada H, Bodyak N, Kang PM, Toltl L, Belikoff B, Buras J, Simms BT, Mizgerd JP, Carmeliet P, Karumanchi SA, Aird WC.

J Exp Med. 2006 Jun 12;203(6):1447-58. Epub 2006 May 15.

17.

Regulation of vascular endothelial growth factor expression and vascularization in the myocardium by insulin receptor and PI3K/Akt pathways in insulin resistance and ischemia.

He Z, Opland DM, Way KJ, Ueki K, Bodyak N, Kang PM, Izumo S, Kulkarni RN, Wang B, Liao R, Kahn CR, King GL.

Arterioscler Thromb Vasc Biol. 2006 Apr;26(4):787-93. Epub 2006 Feb 9.

18.

Genetic expression profiles during physiological and pathological cardiac hypertrophy and heart failure in rats.

Kong SW, Bodyak N, Yue P, Liu Z, Brown J, Izumo S, Kang PM.

Physiol Genomics. 2005 Mar 21;21(1):34-42. Epub 2004 Dec 28.

PMID:
15623566
19.

Alterations in apoptosis regulatory factors during hypertrophy and heart failure.

Kang PM, Yue P, Liu Z, Tarnavski O, Bodyak N, Izumo S.

Am J Physiol Heart Circ Physiol. 2004 Jul;287(1):H72-80. Epub 2004 Mar 4.

20.

Mutation and intracellular clonal expansion of mitochondrial genomes: two synergistic components of the aging process?

Kraytsberg Y, Nekhaeva E, Bodyak NB, Khrapko K.

Mech Ageing Dev. 2003 Jan;124(1):49-53. Review.

PMID:
12618006
21.

Carbon monoxide suppresses arteriosclerotic lesions associated with chronic graft rejection and with balloon injury.

Otterbein LE, Zuckerbraun BS, Haga M, Liu F, Song R, Usheva A, Stachulak C, Bodyak N, Smith RN, Csizmadia E, Tyagi S, Akamatsu Y, Flavell RJ, Billiar TR, Tzeng E, Bach FH, Choi AM, Soares MP.

Nat Med. 2003 Feb;9(2):183-90. Epub 2003 Jan 21.

PMID:
12539038
22.

Gene expression profiling of the aging mouse cardiac myocytes.

Bodyak N, Kang PM, Hiromura M, Sulijoadikusumo I, Horikoshi N, Khrapko K, Usheva A.

Nucleic Acids Res. 2002 Sep 1;30(17):3788-94.

24.

Frequent intracellular clonal expansions of somatic mtDNA mutations: significance and mechanisms.

Coller HA, Bodyak ND, Khrapko K.

Ann N Y Acad Sci. 2002 Apr;959:434-47.

PMID:
11976216
25.

Clonally expanded mtDNA point mutations are abundant in individual cells of human tissues.

Nekhaeva E, Bodyak ND, Kraytsberg Y, McGrath SB, Van Orsouw NJ, Pluzhnikov A, Wei JY, Vijg J, Khrapko K.

Proc Natl Acad Sci U S A. 2002 Apr 16;99(8):5521-6. Epub 2002 Apr 9.

27.

High frequency of homoplasmic mitochondrial DNA mutations in human tumors can be explained without selection.

Coller HA, Khrapko K, Bodyak ND, Nekhaeva E, Herrero-Jimenez P, Thilly WG.

Nat Genet. 2001 Jun;28(2):147-50.

PMID:
11381261
28.
29.

Does intranasal application of zinc sulfate produce anosmia in the rat?

Slotnick B, Glover P, Bodyak N.

Behav Neurosci. 2000 Aug;114(4):814-29.

PMID:
10959540
30.
31.

Cell-by-cell scanning of whole mitochondrial genomes in aged human heart reveals a significant fraction of myocytes with clonally expanded deletions.

Khrapko K, Bodyak N, Thilly WG, van Orsouw NJ, Zhang X, Coller HA, Perls TT, Upton M, Vijg J, Wei JY.

Nucleic Acids Res. 1999 Jun 1;27(11):2434-41.

32.

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