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Corrigendum to "Anxiety, neuroinflammation, cholinergic and GABAergic abnormalities are early markers of Gulf War illness in a mouse model of the disease" [Brain Res. 1681 (2018) 34-43].

Carreras I, Aytan N, Mellott T, Choi JK, Lehar M, Crabtree L, Leite-Morris K, Jenkins BG, Blusztajn JK, Dedeoglu A.

Brain Res. 2018 Mar 12. pii: S0006-8993(18)30132-X. doi: 10.1016/j.brainres.2018.03.005. [Epub ahead of print] No abstract available.


Protective effects of 7,8-dihydroxyflavone on neuropathological and neurochemical changes in a mouse model of Alzheimer's disease.

Aytan N, Choi JK, Carreras I, Crabtree L, Nguyen B, Lehar M, Blusztajn JK, Jenkins BG, Dedeoglu A.

Eur J Pharmacol. 2018 Mar 3. pii: S0014-2999(18)30130-4. doi: 10.1016/j.ejphar.2018.02.045. [Epub ahead of print]


Pramlintide: The Effects of a Single Drug Injection on Blood Phosphatidylcholine Profile for Alzheimer's Disease.

Tao Q, Zhu H, Chen X, Stern RA, Kowall N, Au R, Blusztajn JK, Qiu WQ; Alzheimer’s Disease Metabolomics Consortium.

J Alzheimers Dis. 2018;62(2):597-609. doi: 10.3233/JAD-170948.


Anxiety, neuroinflammation, cholinergic and GABAergic abnormalities are early markers of Gulf War illness in a mouse model of the disease.

Carreras I, Aytan N, Mellott T, Choi JK, Lehar M, Crabtree L, Leite-Morris K, Jenkins BG, Blusztajn JK, Dedeoglu A.

Brain Res. 2018 Feb 15;1681:34-43. doi: 10.1016/j.brainres.2017.12.030. Epub 2017 Dec 24. Erratum in: Brain Res. 2018 Mar 8;:.


Neuroprotective Actions of Dietary Choline.

Blusztajn JK, Slack BE, Mellott TJ.

Nutrients. 2017 Jul 28;9(8). pii: E815. doi: 10.3390/nu9080815. Review.


Methionine Sulfoxide Reductase-B3 (MsrB3) Protein Associates with Synaptic Vesicles and its Expression Changes in the Hippocampi of Alzheimer's Disease Patients.

Adams SL, Benayoun L, Tilton K, Chavez OR, Himali JJ, Blusztajn JK, Seshadri S, Delalle I.

J Alzheimers Dis. 2017;60(1):43-56. doi: 10.3233/JAD-170459.


Correction: Perinatal Choline Supplementation Reduces Amyloidosis and Increases Choline Acetyltransferase Expression in the Hippocampus of the APPswePS1dE9 Alzheimer's Disease Model Mice.

Mellott TJ, Huleatt OM, Shade BN, Pender SM, Liu YB, Slack BE, Blusztajn JK.

PLoS One. 2017 Mar 23;12(3):e0174875. doi: 10.1371/journal.pone.0174875. eCollection 2017.


Perinatal Choline Supplementation Reduces Amyloidosis and Increases Choline Acetyltransferase Expression in the Hippocampus of the APPswePS1dE9 Alzheimer's Disease Model Mice.

Mellott TJ, Huleatt OM, Shade BN, Pender SM, Liu YB, Slack BE, Blusztajn JK.

PLoS One. 2017 Jan 19;12(1):e0170450. doi: 10.1371/journal.pone.0170450. eCollection 2017. Erratum in: PLoS One. 2017 Mar 23;12 (3):e0174875.


Amylin Treatment Reduces Neuroinflammation and Ameliorates Abnormal Patterns of Gene Expression in the Cerebral Cortex of an Alzheimer's Disease Mouse Model.

Wang E, Zhu H, Wang X, Gower AC, Wallack M, Blusztajn JK, Kowall N, Qiu WQ.

J Alzheimers Dis. 2017;56(1):47-61. doi: 10.3233/JAD-160677.


Comment on "Multiple repressive mechanisms in the hippocampus during memory formation".

Mathew RS, Mullan H, Blusztajn JK, Lehtinen MK.

Science. 2016 Jul 29;353(6298):453.


Intrinsic Cholinergic Neurons in the Hippocampus: Fact or Artifact?

Blusztajn JK, Rinnofner J.

Front Synaptic Neurosci. 2016 Mar 10;8:6. doi: 10.3389/fnsyn.2016.00006. eCollection 2016.


High maternal choline consumption during pregnancy and nursing alleviates deficits in social interaction and improves anxiety-like behaviors in the BTBR T+Itpr3tf/J mouse model of autism.

Langley EA, Krykbaeva M, Blusztajn JK, Mellott TJ.

Behav Brain Res. 2015 Feb 1;278:210-20. doi: 10.1016/j.bbr.2014.09.043. Epub 2014 Oct 6.


IGF2 ameliorates amyloidosis, increases cholinergic marker expression and raises BMP9 and neurotrophin levels in the hippocampus of the APPswePS1dE9 Alzheimer's disease model mice.

Mellott TJ, Pender SM, Burke RM, Langley EA, Blusztajn JK.

PLoS One. 2014 Apr 14;9(4):e94287. doi: 10.1371/journal.pone.0094287. eCollection 2014.


BMP9 ameliorates amyloidosis and the cholinergic defect in a mouse model of Alzheimer's disease.

Burke RM, Norman TA, Haydar TF, Slack BE, Leeman SE, Blusztajn JK, Mellott TJ.

Proc Natl Acad Sci U S A. 2013 Nov 26;110(48):19567-72. doi: 10.1073/pnas.1319297110. Epub 2013 Nov 11.


Neuroprotective actions of perinatal choline nutrition.

Blusztajn JK, Mellott TJ.

Clin Chem Lab Med. 2013 Mar 1;51(3):591-9. doi: 10.1515/cclm-2012-0635. Review.


Chronic traumatic encephalopathy in blast-exposed military veterans and a blast neurotrauma mouse model.

Goldstein LE, Fisher AM, Tagge CA, Zhang XL, Velisek L, Sullivan JA, Upreti C, Kracht JM, Ericsson M, Wojnarowicz MW, Goletiani CJ, Maglakelidze GM, Casey N, Moncaster JA, Minaeva O, Moir RD, Nowinski CJ, Stern RA, Cantu RC, Geiling J, Blusztajn JK, Wolozin BL, Ikezu T, Stein TD, Budson AE, Kowall NW, Chargin D, Sharon A, Saman S, Hall GF, Moss WC, Cleveland RO, Tanzi RE, Stanton PK, McKee AC.

Sci Transl Med. 2012 May 16;4(134):134ra60. doi: 10.1126/scitranslmed.3003716.


Choline nutrition programs brain development via DNA and histone methylation.

Blusztajn JK, Mellott TJ.

Cent Nerv Syst Agents Med Chem. 2012 Jun;12(2):82-94. Review.


Prenatal choline deficiency does not enhance hippocampal vulnerability after kainic acid-induced seizures in adulthood.

Wong-Goodrich SJ, Tognoni CM, Mellott TJ, Glenn MJ, Blusztajn JK, Williams CL.

Brain Res. 2011 Sep 21;1413:84-97. doi: 10.1016/j.brainres.2011.07.042. Epub 2011 Jul 24.


BMP9 protects septal neurons from axotomy-evoked loss of cholinergic phenotype.

Lopez-Coviella I, Mellott TJ, Schnitzler AC, Blusztajn JK.

PLoS One. 2011;6(6):e21166. doi: 10.1371/journal.pone.0021166. Epub 2011 Jun 13.


Surface expression and limited proteolysis of ADAM10 are increased by a dominant negative inhibitor of dynamin.

Carey RM, Blusztajn JK, Slack BE.

BMC Cell Biol. 2011 May 17;12:20. doi: 10.1186/1471-2121-12-20.


BMP9 (bone morphogenetic protein 9) induces NGF as an autocrine/paracrine cholinergic trophic factor in developing basal forebrain neurons.

Schnitzler AC, Mellott TJ, Lopez-Coviella I, Tallini YN, Kotlikoff MI, Follettie MT, Blusztajn JK.

J Neurosci. 2010 Jun 16;30(24):8221-8. doi: 10.1523/JNEUROSCI.5611-09.2010.


Deletion of murine choline dehydrogenase results in diminished sperm motility.

Johnson AR, Craciunescu CN, Guo Z, Teng YW, Thresher RJ, Blusztajn JK, Zeisel SH.

FASEB J. 2010 Aug;24(8):2752-61. doi: 10.1096/fj.09-153718. Epub 2010 Apr 6.


Water maze experience and prenatal choline supplementation differentially promote long-term hippocampal recovery from seizures in adulthood.

Wong-Goodrich SJ, Glenn MJ, Mellott TJ, Liu YB, Blusztajn JK, Williams CL.

Hippocampus. 2011 Jun;21(6):584-608. doi: 10.1002/hipo.20783. Epub 2010 Mar 15.


Raising gestational choline intake alters gene expression in DMBA-evoked mammary tumors and prolongs survival.

Kovacheva VP, Davison JM, Mellott TJ, Rogers AE, Yang S, O'Brien MJ, Blusztajn JK.

FASEB J. 2009 Apr;23(4):1054-63. doi: 10.1096/fj.08-122168. Epub 2008 Dec 1.


Developmental periods of choline sensitivity provide an ontogenetic mechanism for regulating memory capacity and age-related dementia.

Meck WH, Williams CL, Cermak JM, Blusztajn JK.

Front Integr Neurosci. 2008 May 3;1:7. doi: 10.3389/neuro.07.007.2007. eCollection 2007.


Differential modulation of nerve growth factor receptor (p75) and cholinergic gene expression in purified p75-expressing and non-expressing basal forebrain neurons by BMP9.

Schnitzler AC, Lopez-Coviella I, Blusztajn JK.

Brain Res. 2008 Dec 30;1246:19-28. doi: 10.1016/j.brainres.2008.09.085. Epub 2008 Oct 14.


Nerve growth factor regulates the expression of the cholinergic locus and the high-affinity choline transporter via the Akt/PKB signaling pathway.

Madziar B, Shah S, Brock M, Burke R, Lopez-Coviella I, Nickel AC, Cakal EB, Blusztajn JK, Berse B.

J Neurochem. 2008 Dec;107(5):1284-93. doi: 10.1111/j.1471-4159.2008.05681.x. Epub 2008 Sep 13.


Prenatal choline supplementation in rats increases the expression of IGF2 and its receptor IGF2R and enhances IGF2-induced acetylcholine release in hippocampus and frontal cortex.

Napoli I, Blusztajn JK, Mellott TJ.

Brain Res. 2008 Oct 27;1237:124-35. doi: 10.1016/j.brainres.2008.08.046. Epub 2008 Aug 28.


Age-related declines in exploratory behavior and markers of hippocampal plasticity are attenuated by prenatal choline supplementation in rats.

Glenn MJ, Kirby ED, Gibson EM, Wong-Goodrich SJ, Mellott TJ, Blusztajn JK, Williams CL.

Brain Res. 2008 Oct 27;1237:110-23. doi: 10.1016/j.brainres.2008.08.049. Epub 2008 Aug 28.


Spatial memory and hippocampal plasticity are differentially sensitive to the availability of choline in adulthood as a function of choline supply in utero.

Wong-Goodrich SJ, Glenn MJ, Mellott TJ, Blusztajn JK, Meck WH, Williams CL.

Brain Res. 2008 Oct 27;1237:153-66. doi: 10.1016/j.brainres.2008.08.074. Epub 2008 Sep 4.


Prenatal choline supplementation attenuates neuropathological response to status epilepticus in the adult rat hippocampus.

Wong-Goodrich SJ, Mellott TJ, Glenn MJ, Blusztajn JK, Williams CL.

Neurobiol Dis. 2008 May;30(2):255-69. doi: 10.1016/j.nbd.2008.01.008. Epub 2008 Feb 16.


Differential regulation of mTOR-dependent S6 phosphorylation by muscarinic acetylcholine receptor subtypes.

Slack BE, Blusztajn JK.

J Cell Biochem. 2008 Aug 1;104(5):1818-31. doi: 10.1002/jcb.21745.


Purification and culture of nerve growth factor receptor (p75)-expressing basal forebrain cholinergic neurons.

Schnitzler AC, Lopez-Coviella I, Blusztajn JK.

Nat Protoc. 2008;3(1):34-40. doi: 10.1038/nprot.2007.477.


Gestational choline deficiency causes global and Igf2 gene DNA hypermethylation by up-regulation of Dnmt1 expression.

Kovacheva VP, Mellott TJ, Davison JM, Wagner N, Lopez-Coviella I, Schnitzler AC, Blusztajn JK.

J Biol Chem. 2007 Oct 26;282(43):31777-88. Epub 2007 Aug 27.


A cyclic peptide that binds p75(NTR) protects neurones from beta amyloid (1-40)-induced cell death.

Yaar M, Zhai S, Panova I, Fine RE, Eisenhauer PB, Blusztajn JK, Lopez-Coviella I, Gilchrest BA.

Neuropathol Appl Neurobiol. 2007 Oct;33(5):533-43. Epub 2007 Jun 27.


Prenatal choline availability modulates hippocampal neurogenesis and neurogenic responses to enriching experiences in adult female rats.

Glenn MJ, Gibson EM, Kirby ED, Mellott TJ, Blusztajn JK, Williams CL.

Eur J Neurosci. 2007 Apr;25(8):2473-82.


Differential regulation of the high affinity choline transporter and the cholinergic locus by cAMP signaling pathways.

Brock M, Nickel AC, Madziar B, Blusztajn JK, Berse B.

Brain Res. 2007 May 11;1145:1-10. Epub 2007 Feb 2.


Prenatal choline availability modulates hippocampal and cerebral cortical gene expression.

Mellott TJ, Follettie MT, Diesl V, Hill AA, Lopez-Coviella I, Blusztajn JK.

FASEB J. 2007 May;21(7):1311-23. Epub 2007 Jan 30.


Developmental pattern of expression of BMP receptors and Smads and activation of Smad1 and Smad5 by BMP9 in mouse basal forebrain.

Lopez-Coviella I, Mellott TM, Kovacheva VP, Berse B, Slack BE, Zemelko V, Schnitzler A, Blusztajn JK.

Brain Res. 2006 May 9;1088(1):49-56. Epub 2006 Apr 13.


Expression of high affinity choline transporter during mouse development in vivo and its upregulation by NGF and BMP-4 in vitro.

Berse B, Szczecinska W, Lopez-Coviella I, Madziar B, Zemelko V, Kaminski R, Kozar K, Lips KS, Pfeil U, Blusztajn JK.

Brain Res Dev Brain Res. 2005 Jun 30;157(2):132-40.


Bone morphogenetic protein 9 induces the transcriptome of basal forebrain cholinergic neurons.

Lopez-Coviella I, Follettie MT, Mellott TJ, Kovacheva VP, Slack BE, Diesl V, Berse B, Thies RS, Blusztajn JK.

Proc Natl Acad Sci U S A. 2005 May 10;102(19):6984-9. Epub 2005 May 3.


Modulation of endothelial cell migration by extracellular nucleotides: involvement of focal adhesion kinase and phosphatidylinositol 3-kinase-mediated pathways.

Kaczmarek E, Erb L, Koziak K, Jarzyna R, Wink MR, Guckelberger O, Blusztajn JK, Trinkaus-Randall V, Weisman GA, Robson SC.

Thromb Haemost. 2005 Apr;93(4):735-42.


Nutrients as trophic factors in neurons and the central nervous system: role of retinoic acid.

Malik MA, Blusztajn JK, Greenwood CE.

J Nutr Biochem. 2000 Jan;11(1):2-13.


Choline transporter 1 maintains cholinergic function in choline acetyltransferase haploinsufficiency.

Brandon EP, Mellott T, Pizzo DP, Coufal N, D'Amour KA, Gobeske K, Lortie M, López-Coviella I, Berse B, Thal LJ, Gage FH, Blusztajn JK.

J Neurosci. 2004 Jun 16;24(24):5459-66.


Prenatal choline supplementation advances hippocampal development and enhances MAPK and CREB activation.

Mellott TJ, Williams CL, Meck WH, Blusztajn JK.

FASEB J. 2004 Mar;18(3):545-7. Epub 2004 Jan 8.


Toxicity of glucosylsphingosine (glucopsychosine) to cultured neuronal cells: a model system for assessing neuronal damage in Gaucher disease type 2 and 3.

Schueler UH, Kolter T, Kaneski CR, Blusztajn JK, Herkenham M, Sandhoff K, Brady RO.

Neurobiol Dis. 2003 Dec;14(3):595-601.


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