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In Vivo Dissolution and Systemic Absorption of Immediate Release Ibuprofen in Human Gastrointestinal Tract under Fed and Fasted Conditions.

Koenigsknecht MJ, Baker JR, Wen B, Frances A, Zhang H, Yu A, Zhao T, Tsume Y, Pai MP, Bleske BE, Zhang X, Lionberger R, Lee A, Amidon GL, Hasler WL, Sun D.

Mol Pharm. 2017 Dec 4;14(12):4295-4304. doi: 10.1021/acs.molpharmaceut.7b00425. Epub 2017 Oct 5.


A Comprehensive Functional Assessment of Carboxylesterase 1 Nonsynonymous Polymorphisms.

Wang X, Rida N, Shi J, Wu AH, Bleske BE, Zhu HJ.

Drug Metab Dispos. 2017 Nov;45(11):1149-1155. doi: 10.1124/dmd.117.077669. Epub 2017 Aug 24.


Qualitative Analysis of Student Perceptions Comparing Team-based Learning and Traditional Lecture in a Pharmacotherapeutics Course.

Remington TL, Bleske BE, Bartholomew T, Dorsch MP, Guthrie SK, Klein KC, Tingen JM, Wells TD.

Am J Pharm Educ. 2017 Apr;81(3):55. doi: 10.5688/ajpe81355.


Incorporation of a community pharmacy-based heart failure assessment tool by advanced pharmacy practice experience students.

Kelling SE, Walker PC, Mason JG, Zara N, Bleske BE.

J Am Pharm Assoc (2003). 2017 May - Jun;57(3):382-388. doi: 10.1016/j.japh.2017.01.008. Epub 2017 Mar 9.


Hyponatremia, Cognitive Function, and Mobility in an Outpatient Heart Failure Population.

Albabtain M, Brenner MJ, Nicklas JM, Hummel SL, McCormick MP, Pawlowski JL, Remington TL, Gure TR, Dorsch MP, Bleske BE.

Med Sci Monit. 2016 Dec 18;22:4978-4985.


Surface area-dependence of gas-particle interactions influences pulmonary and neuroinflammatory outcomes.

Tyler CR, Zychowski KE, Sanchez BN, Rivero V, Lucas S, Herbert G, Liu J, Irshad H, McDonald JD, Bleske BE, Campen MJ.

Part Fibre Toxicol. 2016 Dec 1;13(1):64.


Variability in Retail Pricing of Generic Drugs for Heart Failure.

Hauptman PJ, Goff ZD, Vidic A, Chibnall JT, Bleske BE.

JAMA Intern Med. 2017 Jan 1;177(1):126-128. doi: 10.1001/jamainternmed.2016.6955. No abstract available.


A Randomized Crossover Comparison of Team-based Learning and Lecture Format on Learning Outcomes.

Bleske BE, Remington TL, Wells TD, Klein KC, Guthrie SK, Tingen JM, Marshall VD, Dorsch MP.

Am J Pharm Educ. 2016 Sep 25;80(7):120.


Dabigatran etexilate activation is affected by the CES1 genetic polymorphism G143E (rs71647871) and gender.

Shi J, Wang X, Nguyen JH, Bleske BE, Liang Y, Liu L, Zhu HJ.

Biochem Pharmacol. 2016 Nov 1;119:76-84. doi: 10.1016/j.bcp.2016.09.003. Epub 2016 Sep 8.


Cardiovascular risk and treatment for adults with intellectual or developmental disabilities.

Erickson SR, Spoutz P, Dorsch M, Bleske B.

Int J Cardiol. 2016 Oct 15;221:371-5. doi: 10.1016/j.ijcard.2016.07.044. Epub 2016 Jul 5.


Opioid overdose prevention through pharmacy-based naloxone prescription program: Innovations in health care delivery.

Bachyrycz A, Shrestha S, Bleske BE, Tinker D, Bakhireva LN.

Subst Abus. 2017 Jan-Mar;38(1):55-60. doi: 10.1080/08897077.2016.1184739. Epub 2016 May 10.


Sacubitril Is Selectively Activated by Carboxylesterase 1 (CES1) in the Liver and the Activation Is Affected by CES1 Genetic Variation.

Shi J, Wang X, Nguyen J, Wu AH, Bleske BE, Zhu HJ.

Drug Metab Dispos. 2016 Apr;44(4):554-9. doi: 10.1124/dmd.115.068536. Epub 2016 Jan 27.


Nurse-Enhanced Computerized Cognitive Training Increases Serum Brain-Derived Neurotropic Factor Levels and Improves Working Memory in Heart Failure.

Pressler SJ, Titler M, Koelling TM, Riley PL, Jung M, Hoyland-Domenico L, Ronis DL, Smith DG, Bleske BE, Dorsey SG, Giordani B.

J Card Fail. 2015 Aug;21(8):630-41. doi: 10.1016/j.cardfail.2015.05.004. Epub 2015 May 14.


A web application for self-monitoring improves symptoms in chronic systolic heart failure.

Dorsch MP, Farris KB, Bleske BE, Koelling TM.

Telemed J E Health. 2015 Apr;21(4):267-70. doi: 10.1089/tmj.2014.0095. Epub 2015 Feb 5.


Heart failure assessment at the community pharmacy level: a feasibility pilot study.

Bleske BE, Dillman NO, Cornelius D, Ward JK, Burson SC, Diez HL, Pickworth KK, Bennett MS, Nicklas JM, Dorsch MP.

J Am Pharm Assoc (2003). 2014 Nov-Dec;54(6):634-41. doi: 10.1331/JAPhA.2014.14039.


Pharmacotherapy for weight loss: the cardiovascular effects of the old and new agents.

Walter CP, Bleske BE, Dorsch MP.

J Clin Pharm Ther. 2014 Oct;39(5):475-84. doi: 10.1111/jcpt.12177. Epub 2014 Jun 13. Review.


Team-based learning to improve learning outcomes in a therapeutics course sequence.

Bleske BE, Remington TL, Wells TD, Dorsch MP, Guthrie SK, Stumpf JL, Alaniz MC, Ellingrod VL, Tingen JM.

Am J Pharm Educ. 2014 Feb 12;78(1):13. doi: 10.5688/ajpe78113.


Vitamin D receptor genetics on extracellular matrix biomarkers and hemodynamics in systolic heart failure.

Dorsch MP, Nemerovski CW, Ellingrod VL, Cowger JA, Dyke DB, Koelling TM, Wu AH, Aaronson KD, Simpson RU, Bleske BE.

J Cardiovasc Pharmacol Ther. 2014 Sep;19(5):439-45. doi: 10.1177/1074248413517747. Epub 2014 Feb 4.


Baseline albumin is associated with worsening renal function in patients with acute decompensated heart failure receiving continuous infusion loop diuretics.

Clarke MM, Dorsch MP, Kim S, Aaronson KD, Koelling TM, Bleske BE.

Pharmacotherapy. 2013 Jun;33(6):583-8. doi: 10.1002/phar.1241. Epub 2013 Apr 1.


The effect of continuous infusion loop diuretics in patients with acute decompensated heart failure with hypoalbuminemia.

Bleske BE, Clark MM, Wu AH, Dorsch MP.

J Cardiovasc Pharmacol Ther. 2013 Jul;18(4):334-7. doi: 10.1177/1074248412474347. Epub 2013 Feb 18.


Heart failure: clinical problem and management issues.

Nicklas JM, Bleske BE, Van Harrison R, Hogikyan RV, Kwok Y, Chavey WE.

Prim Care. 2013 Mar;40(1):17-42. doi: 10.1016/j.pop.2012.11.010. Review.


Clinical utility of azilsartan-chlorthalidone fixed combination in the management of hypertension.

Shuster JE, Bleske BE, Dorsch MP.

Vasc Health Risk Manag. 2012;8:381-7. doi: 10.2147/VHRM.S22583. Epub 2012 Jun 13. Review.


Cardiovascular risk among university students from developed and developing nations.

Bleske BE, Erickson SR, Fahoum S, Devarakonda KR, Welage LS, Koudmani M, Pantham N, Edwin SB, Devarakonda S, Shea MJ, Martha S, Khalidi N.

Open Cardiovasc Med J. 2011;5:117-22. doi: 10.2174/1874192401105010117. Epub 2011 May 13.


Chlorthalidone reduces cardiovascular events compared with hydrochlorothiazide: a retrospective cohort analysis.

Dorsch MP, Gillespie BW, Erickson SR, Bleske BE, Weder AB.

Hypertension. 2011 Apr;57(4):689-94. doi: 10.1161/HYPERTENSIONAHA.110.161505. Epub 2011 Mar 7.


Treatment of heart failure with preserved ejection fraction.

Barnes MM, Dorsch MP, Hummel SL, Koelling TM, Bleske BE.

Pharmacotherapy. 2011 Mar;31(3):312-31. doi: 10.1592/phco.31.3.312. Review.


The impact of paroxetine coadministration on stereospecific carvedilol pharmacokinetics.

Stout SM, Nielsen J, Bleske BE, Shea M, Brook R, Kerber K, Welage LS.

J Cardiovasc Pharmacol Ther. 2010 Dec;15(4):373-9. doi: 10.1177/1074248410372926. Epub 2010 Aug 12.


Influence of metoprolol dosage release formulation on the pharmacokinetic drug interaction with paroxetine.

Stout SM, Nielsen J, Welage LS, Shea M, Brook R, Kerber K, Bleske BE.

J Clin Pharmacol. 2011 Mar;51(3):389-96. doi: 10.1177/0091270010365559. Epub 2010 Apr 16.


Key articles related to complementary and alternative medicine in cardiovascular disease: part 1.

Chow SL, Dorsch MP, Dunn SP, Jackevicius CA, Page RL 2nd, Trujillo T, Vardeny O, Wiggins B, Bleske BE.

Pharmacotherapy. 2010 Jan;30(1):109. doi: 10.1592/phco.30.1.109.


Vitamin D and cardiovascular disease.

Nemerovski CW, Dorsch MP, Simpson RU, Bone HG, Aaronson KD, Bleske BE.

Pharmacotherapy. 2009 Jun;29(6):691-708. doi: 10.1592/phco.29.6.691. Review.


Effects of hawthorn on the progression of heart failure in a rat model of aortic constriction.

Hwang HS, Boluyt MO, Converso K, Russell MW, Bleske BE.

Pharmacotherapy. 2009 Jun;29(6):639-48. doi: 10.1592/phco.29.6.639.


Lack of interaction between the peptidomimetic substrates captopril and cephradine.

Foster DR, Yee S, Bleske BE, Carver PL, Shea MJ, Menon SS, Ramachandran C, Welage LS, Amidon GL.

J Clin Pharmacol. 2009 Mar;49(3):360-7. doi: 10.1177/0091270008329554.


Nutrition and heart failure: impact of drug therapies and management strategies.

Dunn SP, Bleske B, Dorsch M, Macaulay T, Van Tassell B, Vardeny O.

Nutr Clin Pract. 2009 Feb-Mar;24(1):60-75. doi: 10.1177/0884533608329299. Review.


Photoinstability of S-nitrosothiols during sampling of whole blood: a likely source of error and variability in S-nitrosothiol measurements.

Wu Y, Zhang F, Wang Y, Krishnamoorthy M, Roy-Chaudhury P, Bleske BE, Meyerhoff ME.

Clin Chem. 2008 May;54(5):916-8. doi: 10.1373/clinchem.2007.102103.


Pharmacologic management of heart failure caused by systolic dysfunction.

Chavey WE, Bleske BE, Van Harrison R, Hogikyan RV, Kesterson SK, Nicklas JM.

Am Fam Physician. 2008 Apr 1;77(7):957-64. Review.


Effects of hawthorn on cardiac remodeling and left ventricular dysfunction after 1 month of pressure overload-induced cardiac hypertrophy in rats.

Hwang HS, Bleske BE, Ghannam MM, Converso K, Russell MW, Hunter JC, Boluyt MO.

Cardiovasc Drugs Ther. 2008 Feb;22(1):19-28. doi: 10.1007/s10557-008-6082-2. Epub 2008 Jan 20.


Evaluation of hawthorn extract on immunomodulatory biomarkers in a pressure overload model of heart failure.

Bleske BE, Zineh I, Hwang HS, Welder GJ, Ghannam MM, Boluyt MO.

Med Sci Monit. 2007 Dec;13(12):BR255-8.


Evaluation of immunomodulatory biomarkers in a pressure overload model of heart failure.

Bleske BE, Hwang HS, Zineh I, Ghannam MG, Boluyt MO.

Pharmacotherapy. 2007 Apr;27(4):504-9.


Key articles, guidelines, and consensus papers relative to the treatment of dyslipidemias--2005.

Ito MK, Cheung RJ, Gupta EK, Birtcher KK, Chong PH, Bianco TM, Bleske BE.

Pharmacotherapy. 2006 Jul;26(7):939-1010. Review.


3-HMG-Coenzyme A reductase inhibition and extracellular matrix gene expression in the pressure-overloaded rat heart.

Cirrincione GM, Boluyt MO, Hwang HS, Bleske BE.

J Cardiovasc Pharmacol. 2006 Apr;47(4):521-30.


Loading, pretreatment, and interindividual variability issues with clopidogrel dosing.

Bates ER, Lau WC, Bleske BE.

Circulation. 2005 May 24;111(20):2557-9. No abstract available.


Food: an unrecognized source of loop diuretic resistance.

Bard RL, Bleske BE, Nicklas JM.

Pharmacotherapy. 2004 May;24(5):630-7. Review.


Controversies in the use of beta blockers in heart failure.

Chavey WE 2nd, Bleske BE, Nicklas JM.

Congest Heart Fail. 2003 Sep-Oct;9(5):255-62. Review.


Interaction study between digoxin and a preparation of hawthorn (Crataegus oxyacantha).

Tankanow R, Tamer HR, Streetman DS, Smith SG, Welton JL, Annesley T, Aaronson KD, Bleske BE.

J Clin Pharmacol. 2003 Jun;43(6):637-42.


Hematologic and chemical changes observed during and after cardiac arrest in a canine model--a pilot study.

Bleske BE, Song J, Chow MS, Kluger J, White CM.

Pharmacotherapy. 2001 Oct;21(10):1187-91.


Guideline for the management of heart failure caused by systolic dysfunction: part II. Treatment.

Chavey WE 2nd, Blaum CS, Bleske BE, Harrison RV, Kesterson S, Nicklas JM; American Heart Association.

Am Fam Physician. 2001 Sep 15;64(6):1045-54.


Guideline for the management of heart failure caused by systolic dysfunction: Part I. Guideline development, etiology and diagnosis.

Chavey WE 2nd, Blaum CS, Bleske BE, Harrison RV, Kesterson S, Nicklas JM.

Am Fam Physician. 2001 Sep 1;64(5):769-74. Review.


The effect of pravastatin and atorvastatin on coenzyme Q10.

Bleske BE, Willis RA, Anthony M, Casselberry N, Datwani M, Uhley VE, Secontine SG, Shea MJ.

Am Heart J. 2001 Aug;142(2):E2.


Evolution and pathophysiology of chronic systolic heart failure.

Bleske BE.

Pharmacotherapy. 2000 Nov;20(11 Pt 2):349S-358S. Review.

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