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Items: 1 to 50 of 178

1.

Antibody Specificity Profiling Using Protein Microarrays.

Ramos-López P, Irizarry J, Pino I, Blackshaw S.

Methods Mol Biol. 2018;1785:223-229. doi: 10.1007/978-1-4939-7841-0_14.

PMID:
29714021
2.

Foxd1 is required for terminal differentiation of anterior hypothalamic neuronal subtypes.

Newman EA, Kim DW, Wan J, Wang J, Qian J, Blackshaw S.

Dev Biol. 2018 Apr 19. pii: S0012-1606(17)30906-5. doi: 10.1016/j.ydbio.2018.04.012. [Epub ahead of print]

PMID:
29679559
3.

Ldb1- and Rnf12-dependent regulation of Lhx2 controls the relative balance between neurogenesis and gliogenesis in the retina.

de Melo J, Clark BS, Venkataraman A, Shiau F, Zibetti C, Blackshaw S.

Development. 2018 Apr 30;145(9). pii: dev159970. doi: 10.1242/dev.159970.

PMID:
29650591
4.

A toolbox of immunoprecipitation-grade monoclonal antibodies to human transcription factors.

Venkataraman A, Yang K, Irizarry J, Mackiewicz M, Mita P, Kuang Z, Xue L, Ghosh D, Liu S, Ramos P, Hu S, Bayron Kain D, Keegan S, Saul R, Colantonio S, Zhang H, Behn FP, Song G, Albino E, Asencio L, Ramos L, Lugo L, Morell G, Rivera J, Ruiz K, Almodovar R, Nazario L, Murphy K, Vargas I, Rivera-Pacheco ZA, Rosa C, Vargas M, McDade J, Clark BS, Yoo S, Khambadkone SG, de Melo J, Stevanovic M, Jiang L, Li Y, Yap WY, Jones B, Tandon A, Campbell E, Montelione GT, Anderson S, Myers RM, Boeke JD, Fenyö D, Whiteley G, Bader JS, Pino I, Eichinger DJ, Zhu H, Blackshaw S.

Nat Methods. 2018 Mar 19. doi: 10.1038/nmeth.4632. [Epub ahead of print]

PMID:
29638227
5.

ATAC-Seq analysis reveals a widespread decrease of chromatin accessibility in age-related macular degeneration.

Wang J, Zibetti C, Shang P, Sripathi SR, Zhang P, Cano M, Hoang T, Xia S, Ji H, Merbs SL, Zack DJ, Handa JT, Sinha D, Blackshaw S, Qian J.

Nat Commun. 2018 Apr 10;9(1):1364. doi: 10.1038/s41467-018-03856-y.

6.

Regulation and function of neurogenesis in the adult mammalian hypothalamus.

Yoo S, Blackshaw S.

Prog Neurobiol. 2018 Apr 6. pii: S0301-0082(17)30200-9. doi: 10.1016/j.pneurobio.2018.04.001. [Epub ahead of print] Review.

PMID:
29631023
7.

Global Identification of Small Ubiquitin-related Modifier (SUMO) Substrates Reveals Crosstalk between SUMOylation and Phosphorylation Promotes Cell Migration.

Uzoma I, Hu J, Cox E, Xia S, Zhou J, Rho HS, Guzzo C, Paul C, Ajala O, Goodwin CR, Jeong J, Moore C, Zhang H, Meluh P, Blackshaw S, Matunis M, Qian J, Zhu H.

Mol Cell Proteomics. 2018 May;17(5):871-888. doi: 10.1074/mcp.RA117.000014. Epub 2018 Feb 8.

8.

In Vivo Electroporation of Developing Mouse Retina.

de Melo J, Blackshaw S.

Methods Mol Biol. 2018;1715:101-111. doi: 10.1007/978-1-4939-7522-8_8.

PMID:
29188509
9.

Pax6 is essential for the generation of late-born retinal neurons and for inhibition of photoreceptor-fate during late stages of retinogenesis.

Remez LA, Onishi A, Menuchin-Lasowski Y, Biran A, Blackshaw S, Wahlin KJ, Zack DJ, Ashery-Padan R.

Dev Biol. 2017 Dec 1;432(1):140-150. doi: 10.1016/j.ydbio.2017.09.030. Epub 2017 Oct 7.

10.

Corrigendum: Lhx6-positive GABA-releasing neurons of the zona incerta promote sleep.

Liu K, Kim J, Kim DW, Stephanie Zhang Y, Bao H, Denaxa M, Lim SA, Kim E, Liu C, Wickersham IR, Pachnis V, Hattar S, Song J, Brown SP, Blackshaw S.

Nature. 2017 Oct 26;550(7677):548. doi: 10.1038/nature24274. Epub 2017 Sep 27.

11.

Lhx6-positive GABA-releasing neurons of the zona incerta promote sleep.

Liu K, Kim J, Kim DW, Zhang YS, Bao H, Denaxa M, Lim SA, Kim E, Liu C, Wickersham IR, Pachnis V, Hattar S, Song J, Brown SP, Blackshaw S.

Nature. 2017 Aug 31;548(7669):582-587. doi: 10.1038/nature23663. Epub 2017 Aug 23. Erratum in: Nature. 2017 Sep 27;:.

12.

Understanding the Role of lncRNAs in Nervous System Development.

Clark BS, Blackshaw S.

Adv Exp Med Biol. 2017;1008:253-282. doi: 10.1007/978-981-10-5203-3_9. Review.

13.

Assessing the model transferability for prediction of transcription factor binding sites based on chromatin accessibility.

Liu S, Zibetti C, Wan J, Wang G, Blackshaw S, Qian J.

BMC Bioinformatics. 2017 Jul 27;18(1):355. doi: 10.1186/s12859-017-1769-7.

14.

Regulation of Body Weight and Metabolism by Tanycyte-Derived Neurogenesis in Young Adult Mice.

Blackshaw S, Lee DA, Pak T, Yoo S.

In: Pfaff D, Christen Y, editors. Stem Cells in Neuroendocrinology [Internet]. Cham (CH): Springer; 2016.
2016 Jul 27.

15.

Global Analysis of SUMO-Binding Proteins Identifies SUMOylation as a Key Regulator of the INO80 Chromatin Remodeling Complex.

Cox E, Hwang W, Uzoma I, Hu J, Guzzo CM, Jeong J, Matunis MJ, Qian J, Zhu H, Blackshaw S.

Mol Cell Proteomics. 2017 May;16(5):812-823. doi: 10.1074/mcp.M116.063719. Epub 2017 Mar 2.

16.

The long non-coding RNA NEAT1 is responsive to neuronal activity and is associated with hyperexcitability states.

Barry G, Briggs JA, Hwang DW, Nayler SP, Fortuna PR, Jonkhout N, Dachet F, Maag JL, Mestdagh P, Singh EM, Avesson L, Kaczorowski DC, Ozturk E, Jones NC, Vetter I, Arriola-Martinez L, Hu J, Franco GR, Warn VM, Gong A, Dinger ME, Rigo F, Lipovich L, Morris MJ, O'Brien TJ, Lee DS, Loeb JA, Blackshaw S, Mattick JS, Wolvetang EJ.

Sci Rep. 2017 Jan 5;7:40127. doi: 10.1038/srep40127.

17.

An LHX1-Regulated Transcriptional Network Controls Sleep/Wake Coupling and Thermal Resistance of the Central Circadian Clockworks.

Bedont JL, LeGates TA, Buhr E, Bathini A, Ling JP, Bell B, Wu MN, Wong PC, Van Gelder RN, Mongrain V, Hattar S, Blackshaw S.

Curr Biol. 2017 Jan 9;27(1):128-136. doi: 10.1016/j.cub.2016.11.008. Epub 2016 Dec 22.

18.

A nuclease that mediates cell death induced by DNA damage and poly(ADP-ribose) polymerase-1.

Wang Y, An R, Umanah GK, Park H, Nambiar K, Eacker SM, Kim B, Bao L, Harraz MM, Chang C, Chen R, Wang JE, Kam TI, Jeong JS, Xie Z, Neifert S, Qian J, Andrabi SA, Blackshaw S, Zhu H, Song H, Ming GL, Dawson VL, Dawson TM.

Science. 2016 Oct 7;354(6308). pii: aad6872.

19.

Control of lens development by Lhx2-regulated neuroretinal FGFs.

Thein T, de Melo J, Zibetti C, Clark BS, Juarez F, Blackshaw S.

Development. 2016 Nov 1;143(21):3994-4002. Epub 2016 Sep 15.

20.

The stage-dependent roles of Ldb1 and functional redundancy with Ldb2 in mammalian retinogenesis.

Gueta K, David A, Cohen T, Menuchin-Lasowski Y, Nobel H, Narkis G, Li L, Love P, de Melo J, Blackshaw S, Westphal H, Ashery-Padan R.

Development. 2016 Nov 15;143(22):4182-4192. Epub 2016 Oct 3.

21.

The NIH Protein Capture Reagents Program (PCRP): a standardized protein affinity reagent toolbox.

Blackshaw S, Venkataraman A, Irizarry J, Yang K, Anderson S, Campbell E, Gatlin CL, Freeman NL, Basavappa R, Stewart R, Loss MA, Pino I, Zhu H, Bader JS.

Nat Methods. 2016 Sep 29;13(10):805-6. doi: 10.1038/nmeth.4013. No abstract available.

22.

Multiple intrinsic factors act in concert with Lhx2 to direct retinal gliogenesis.

de Melo J, Clark BS, Blackshaw S.

Sci Rep. 2016 Sep 8;6:32757. doi: 10.1038/srep32757.

23.

Penetrance of Congenital Heart Disease in a Mouse Model of Down Syndrome Depends on a Trisomic Potentiator of a Disomic Modifier.

Li H, Edie S, Klinedinst D, Jeong JS, Blackshaw S, Maslen CL, Reeves RH.

Genetics. 2016 Jun;203(2):763-70. doi: 10.1534/genetics.116.188045. Epub 2016 Mar 30.

24.

The nutrient sensor OGT in PVN neurons regulates feeding.

Lagerlöf O, Slocomb JE, Hong I, Aponte Y, Blackshaw S, Hart GW, Huganir RL.

Science. 2016 Mar 18;351(6279):1293-6. doi: 10.1126/science.aad5494.

25.

Lhx2 Is an Essential Factor for Retinal Gliogenesis and Notch Signaling.

de Melo J, Zibetti C, Clark BS, Hwang W, Miranda-Angulo AL, Qian J, Blackshaw S.

J Neurosci. 2016 Feb 24;36(8):2391-405. doi: 10.1523/JNEUROSCI.3145-15.2016.

26.

EphA4 is Involved in Sleep Regulation but Not in the Electrophysiological Response to Sleep Deprivation.

Freyburger M, Pierre A, Paquette G, Bélanger-Nelson E, Bedont J, Gaudreault PO, Drolet G, Laforest S, Blackshaw S, Cermakian N, Doucet G, Mongrain V.

Sleep. 2016 Mar 1;39(3):613-24. doi: 10.5665/sleep.5538.

27.

Constructing the suprachiasmatic nucleus: a watchmaker's perspective on the central clockworks.

Bedont JL, Blackshaw S.

Front Syst Neurosci. 2015 May 8;9:74. doi: 10.3389/fnsys.2015.00074. eCollection 2015. Review.

28.

Identification of SUMO E3 ligase-specific substrates using the HuProt human proteome microarray.

Cox E, Uzoma I, Guzzo C, Jeong JS, Matunis M, Blackshaw S, Zhu H.

Methods Mol Biol. 2015;1295:455-63. doi: 10.1007/978-1-4939-2550-6_32.

29.

Patterning, specification, and differentiation in the developing hypothalamus.

Bedont JL, Newman EA, Blackshaw S.

Wiley Interdiscip Rev Dev Biol. 2015 Sep-Oct;4(5):445-68. doi: 10.1002/wdev.187. Epub 2015 Mar 27. Review.

30.

A conserved regulatory logic controls temporal identity in mouse neural progenitors.

Mattar P, Ericson J, Blackshaw S, Cayouette M.

Neuron. 2015 Feb 4;85(3):497-504. doi: 10.1016/j.neuron.2014.12.052.

31.

The LIM homeodomain factor Lhx2 is required for hypothalamic tanycyte specification and differentiation.

Salvatierra J, Lee DA, Zibetti C, Duran-Moreno M, Yoo S, Newman EA, Wang H, Bedont JL, de Melo J, Miranda-Angulo AL, Gil-Perotin S, Garcia-Verdugo JM, Blackshaw S.

J Neurosci. 2014 Dec 10;34(50):16809-20. doi: 10.1523/JNEUROSCI.1711-14.2014.

32.

Notch3 interactome analysis identified WWP2 as a negative regulator of Notch3 signaling in ovarian cancer.

Jung JG, Stoeck A, Guan B, Wu RC, Zhu H, Blackshaw S, Shih IeM, Wang TL.

PLoS Genet. 2014 Oct 30;10(10):e1004751. doi: 10.1371/journal.pgen.1004751. eCollection 2014 Oct.

33.

Serine racemase regulated by binding to stargazin and PSD-95: potential N-methyl-D-aspartate-α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (NMDA-AMPA) glutamate neurotransmission cross-talk.

Ma TM, Paul BD, Fu C, Hu S, Zhu H, Blackshaw S, Wolosker H, Snyder SH.

J Biol Chem. 2014 Oct 24;289(43):29631-41. doi: 10.1074/jbc.M114.571604. Epub 2014 Aug 27.

34.

Characterization of the SUMO-binding activity of the myeloproliferative and mental retardation (MYM)-type zinc fingers in ZNF261 and ZNF198.

Guzzo CM, Ringel A, Cox E, Uzoma I, Zhu H, Blackshaw S, Wolberger C, Matunis MJ.

PLoS One. 2014 Aug 18;9(8):e105271. doi: 10.1371/journal.pone.0105271. eCollection 2014.

35.

Dietary and sex-specific factors regulate hypothalamic neurogenesis in young adult mice.

Lee DA, Yoo S, Pak T, Salvatierra J, Velarde E, Aja S, Blackshaw S.

Front Neurosci. 2014 Jun 13;8:157. doi: 10.3389/fnins.2014.00157. eCollection 2014.

36.

Long non-coding RNA-dependent transcriptional regulation in neuronal development and disease.

Clark BS, Blackshaw S.

Front Genet. 2014 Jun 6;5:164. doi: 10.3389/fgene.2014.00164. eCollection 2014. Review.

37.

Lhx1 controls terminal differentiation and circadian function of the suprachiasmatic nucleus.

Bedont JL, LeGates TA, Slat EA, Byerly MS, Wang H, Hu J, Rupp AC, Qian J, Wong GW, Herzog ED, Hattar S, Blackshaw S.

Cell Rep. 2014 May 8;7(3):609-22. doi: 10.1016/j.celrep.2014.03.060. Epub 2014 Apr 24.

38.

Rax-CreERT2 knock-in mice: a tool for selective and conditional gene deletion in progenitor cells and radial glia of the retina and hypothalamus.

Pak T, Yoo S, Miranda-Angulo AL, Wang H, Blackshaw S.

PLoS One. 2014 Apr 3;9(4):e90381. doi: 10.1371/journal.pone.0090381. eCollection 2014. Erratum in: PLoS One. 2014 Jul;9(7):e102875. Miranda-Angulo, Ana M [corrected to Miranda-Angulo, Ana L].

39.

WIDE AWAKE mediates the circadian timing of sleep onset.

Liu S, Lamaze A, Liu Q, Tabuchi M, Yang Y, Fowler M, Bharadwaj R, Zhang J, Bedont J, Blackshaw S, Lloyd TE, Montell C, Sehgal A, Koh K, Wu MN.

Neuron. 2014 Apr 2;82(1):151-66. doi: 10.1016/j.neuron.2014.01.040. Epub 2014 Mar 13.

40.

Stage-specific inhibition of TrkB activity leads to long-lasting and sexually dimorphic effects on body weight and hypothalamic gene expression.

Byerly MS, Swanson RD, Wong GW, Blackshaw S.

PLoS One. 2013 Nov 29;8(11):e80781. doi: 10.1371/journal.pone.0080781. eCollection 2013.

41.

Functional interrogation of adult hypothalamic neurogenesis with focal radiological inhibition.

Lee DA, Salvatierra J, Velarde E, Wong J, Ford EC, Blackshaw S.

J Vis Exp. 2013 Nov 14;(81):e50716. doi: 10.3791/50716.

42.

Feed your head: neurodevelopmental control of feeding and metabolism.

Lee DA, Blackshaw S.

Annu Rev Physiol. 2014;76:197-223. doi: 10.1146/annurev-physiol-021113-170347. Epub 2013 Nov 18. Review.

43.

RNA toxicity from the ALS/FTD C9ORF72 expansion is mitigated by antisense intervention.

Donnelly CJ, Zhang PW, Pham JT, Haeusler AR, Mistry NA, Vidensky S, Daley EL, Poth EM, Hoover B, Fines DM, Maragakis N, Tienari PJ, Petrucelli L, Traynor BJ, Wang J, Rigo F, Bennett CF, Blackshaw S, Sattler R, Rothstein JD.

Neuron. 2013 Oct 16;80(2):415-28. doi: 10.1016/j.neuron.2013.10.015. Erratum in: Neuron. 2013 Nov 20;80(4):1102. Heusler, Aaron R [corrected to Haeusler, Aaron R].

44.

Protein microarray characterization of the S-nitrosoproteome.

Lee YI, Giovinazzo D, Kang HC, Lee Y, Jeong JS, Doulias PT, Xie Z, Hu J, Ghasemi M, Ischiropoulos H, Qian J, Zhu H, Blackshaw S, Dawson VL, Dawson TM.

Mol Cell Proteomics. 2014 Jan;13(1):63-72. doi: 10.1074/mcp.M113.032235. Epub 2013 Oct 8.

45.

Estrogen-related receptor β deficiency alters body composition and response to restraint stress.

Byerly MS, Swanson RD, Wong GW, Blackshaw S.

BMC Physiol. 2013 Sep 22;13:10. doi: 10.1186/1472-6793-13-10.

46.

Rax regulates hypothalamic tanycyte differentiation and barrier function in mice.

Miranda-Angulo AL, Byerly MS, Mesa J, Wang H, Blackshaw S.

J Comp Neurol. 2014 Mar;522(4):876-99. doi: 10.1002/cne.23451.

47.

Bcl2-associated athanogene 3 interactome analysis reveals a new role in modulating proteasome activity.

Chen Y, Yang LN, Cheng L, Tu S, Guo SJ, Le HY, Xiong Q, Mo R, Li CY, Jeong JS, Jiang L, Blackshaw S, Bi LJ, Zhu H, Tao SC, Ge F.

Mol Cell Proteomics. 2013 Oct;12(10):2804-19. doi: 10.1074/mcp.M112.025882. Epub 2013 Jul 3.

48.

The long non-coding RNA Gomafu is acutely regulated in response to neuronal activation and involved in schizophrenia-associated alternative splicing.

Barry G, Briggs JA, Vanichkina DP, Poth EM, Beveridge NJ, Ratnu VS, Nayler SP, Nones K, Hu J, Bredy TW, Nakagawa S, Rigo F, Taft RJ, Cairns MJ, Blackshaw S, Wolvetang EJ, Mattick JS.

Mol Psychiatry. 2014 Apr;19(4):486-94. doi: 10.1038/mp.2013.45. Epub 2013 Apr 30.

PMID:
23628989
49.

LHX2 is necessary for the maintenance of optic identity and for the progression of optic morphogenesis.

Roy A, de Melo J, Chaturvedi D, Thein T, Cabrera-Socorro A, Houart C, Meyer G, Blackshaw S, Tole S.

J Neurosci. 2013 Apr 17;33(16):6877-84. doi: 10.1523/JNEUROSCI.4216-12.2013.

50.

Identification of hypothalamic neuron-derived neurotrophic factor as a novel factor modulating appetite.

Byerly MS, Swanson RD, Semsarzadeh NN, McCulloh PS, Kwon K, Aja S, Moran TH, Wong GW, Blackshaw S.

Am J Physiol Regul Integr Comp Physiol. 2013 Jun 15;304(12):R1085-95. doi: 10.1152/ajpregu.00368.2012. Epub 2013 Apr 10.

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