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Items: 1 to 50 of 125

1.

Perturbation-response genes reveal signaling footprints in cancer gene expression.

Schubert M, Klinger B, Klünemann M, Sieber A, Uhlitz F, Sauer S, Garnett MJ, Blüthgen N, Saez-Rodriguez J.

Nat Commun. 2018 Jan 2;9(1):20. doi: 10.1038/s41467-017-02391-6.

2.

Classification of gene signatures for their information value and functional redundancy.

Cantini L, Calzone L, Martignetti L, Rydenfelt M, Blüthgen N, Barillot E, Zinovyev A.

NPJ Syst Biol Appl. 2017 Dec 19;4:2. doi: 10.1038/s41540-017-0038-8. eCollection 2018.

3.

Intensive land use drives small-scale homogenization of plant- and leafhopper communities and promotes generalists.

Chisté MN, Mody K, Kunz G, Gunczy J, Blüthgen N.

Oecologia. 2018 Feb;186(2):529-540. doi: 10.1007/s00442-017-4031-0. Epub 2017 Dec 4.

PMID:
29204693
4.

An immediate-late gene expression module decodes ERK signal duration.

Uhlitz F, Sieber A, Wyler E, Fritsche-Guenther R, Meisig J, Landthaler M, Klinger B, Blüthgen N.

Mol Syst Biol. 2017 Sep 25;13(9):944. doi: 10.15252/msb.20177986. No abstract available.

5.

Nutrient quality of vertebrate dung as a diet for dung beetles.

Frank K, Brückner A, Hilpert A, Heethoff M, Blüthgen N.

Sci Rep. 2017 Sep 22;7(1):12141. doi: 10.1038/s41598-017-12265-y.

6.

Ants at Plant Wounds: A Little-Known Trophic Interaction with Evolutionary Implications for Ant-Plant Interactions.

Staab M, Fornoff F, Klein AM, Blüthgen N.

Am Nat. 2017 Sep;190(3):442-450. doi: 10.1086/692735. Epub 2017 Jun 23.

PMID:
28829637
7.

Patterns and dynamics of neutral lipid fatty acids in ants - implications for ecological studies.

Rosumek FB, Brückner A, Blüthgen N, Menzel F, Heethoff M.

Front Zool. 2017 Jul 13;14:36. doi: 10.1186/s12983-017-0221-1. eCollection 2017.

8.

A compendium of ERK targets.

Ünal EB, Uhlitz F, Blüthgen N.

FEBS Lett. 2017 Sep;591(17):2607-2615. doi: 10.1002/1873-3468.12740. Epub 2017 Jul 25. Review.

PMID:
28675784
9.

Neuronal activity-regulated alternative mRNA splicing.

Hermey G, Blüthgen N, Kuhl D.

Int J Biochem Cell Biol. 2017 Oct;91(Pt B):184-193. doi: 10.1016/j.biocel.2017.06.002. Epub 2017 Jun 4. Review.

PMID:
28591617
10.

An immediate-late gene expression module decodes ERK signal duration.

Uhlitz F, Sieber A, Wyler E, Fritsche-Guenther R, Meisig J, Landthaler M, Klinger B, Blüthgen N.

Mol Syst Biol. 2017 May 3;13(5):928. doi: 10.15252/msb.20177554. Erratum in: Mol Syst Biol. 2017 Sep 25;13(9):944.

11.

Oncogenic β-catenin and PIK3CA instruct network states and cancer phenotypes in intestinal organoids.

Riemer P, Rydenfelt M, Marks M, van Eunen K, Thedieck K, Herrmann BG, Blüthgen N, Sers C, Morkel M.

J Cell Biol. 2017 Jun 5;216(6):1567-1577. doi: 10.1083/jcb.201610058. Epub 2017 Apr 25.

12.

The relationship between epicuticular long-chained hydrocarbons and surface area - volume ratios in insects (Diptera, Hymenoptera, Lepidoptera).

Brückner A, Heethoff M, Blüthgen N.

PLoS One. 2017 Apr 6;12(4):e0175001. doi: 10.1371/journal.pone.0175001. eCollection 2017.

13.

Drug Resistance Mechanisms in Colorectal Cancer Dissected with Cell Type-Specific Dynamic Logic Models.

Eduati F, Doldàn-Martelli V, Klinger B, Cokelaer T, Sieber A, Kogera F, Dorel M, Garnett MJ, Blüthgen N, Saez-Rodriguez J.

Cancer Res. 2017 Jun 15;77(12):3364-3375. doi: 10.1158/0008-5472.CAN-17-0078. Epub 2017 Apr 5.

PMID:
28381545
14.

Profiling the MAPK/ERK dependent and independent activity regulated transcriptional programs in the murine hippocampus in vivo.

Blüthgen N, van Bentum M, Merz B, Kuhl D, Hermey G.

Sci Rep. 2017 Mar 28;7:45101. doi: 10.1038/srep45101.

15.

Ecosystem restoration strengthens pollination network resilience and function.

Kaiser-Bunbury CN, Mougal J, Whittington AE, Valentin T, Gabriel R, Olesen JM, Blüthgen N.

Nature. 2017 Feb 9;542(7640):223-227. doi: 10.1038/nature21071. Epub 2017 Jan 30.

PMID:
28135718
16.

Reciprocal insulation analysis of Hi-C data shows that TADs represent a functionally but not structurally privileged scale in the hierarchical folding of chromosomes.

Zhan Y, Mariani L, Barozzi I, Schulz EG, Blüthgen N, Stadler M, Tiana G, Giorgetti L.

Genome Res. 2017 Mar;27(3):479-490. doi: 10.1101/gr.212803.116. Epub 2017 Jan 5.

17.

Comparison of a teratogenic transcriptome-based predictive test based on human embryonic versus inducible pluripotent stem cells.

Shinde V, Perumal Srinivasan S, Henry M, Rotshteyn T, Hescheler J, Rahnenführer J, Grinberg M, Meisig J, Blüthgen N, Waldmann T, Leist M, Hengstler JG, Sachinidis A.

Stem Cell Res Ther. 2016 Dec 30;7(1):190. doi: 10.1186/s13287-016-0449-2.

18.

Ecological networks are more sensitive to plant than to animal extinction under climate change.

Schleuning M, Fründ J, Schweiger O, Welk E, Albrecht J, Albrecht M, Beil M, Benadi G, Blüthgen N, Bruelheide H, Böhning-Gaese K, Dehling DM, Dormann CF, Exeler N, Farwig N, Harpke A, Hickler T, Kratochwil A, Kuhlmann M, Kühn I, Michez D, Mudri-Stojnić S, Plein M, Rasmont P, Schwabe A, Settele J, Vujić A, Weiner CN, Wiemers M, Hof C.

Nat Commun. 2016 Dec 23;7:13965. doi: 10.1038/ncomms13965.

19.

Land-use intensification causes multitrophic homogenization of grassland communities.

Gossner MM, Lewinsohn TM, Kahl T, Grassein F, Boch S, Prati D, Birkhofer K, Renner SC, Sikorski J, Wubet T, Arndt H, Baumgartner V, Blaser S, Blüthgen N, Börschig C, Buscot F, Diekötter T, Jorge LR, Jung K, Keyel AC, Klein AM, Klemmer S, Krauss J, Lange M, Müller J, Overmann J, Pašalić E, Penone C, Perović DJ, Purschke O, Schall P, Socher SA, Sonnemann I, Tschapka M, Tscharntke T, Türke M, Venter PC, Weiner CN, Werner M, Wolters V, Wurst S, Westphal C, Fischer M, Weisser WW, Allan E.

Nature. 2016 Dec 8;540(7632):266-269. doi: 10.1038/nature20575. Epub 2016 Nov 30.

PMID:
27919075
20.

Biodiversity at multiple trophic levels is needed for ecosystem multifunctionality.

Soliveres S, van der Plas F, Manning P, Prati D, Gossner MM, Renner SC, Alt F, Arndt H, Baumgartner V, Binkenstein J, Birkhofer K, Blaser S, Blüthgen N, Boch S, Böhm S, Börschig C, Buscot F, Diekötter T, Heinze J, Hölzel N, Jung K, Klaus VH, Kleinebecker T, Klemmer S, Krauss J, Lange M, Morris EK, Müller J, Oelmann Y, Overmann J, Pašalić E, Rillig MC, Schaefer HM, Schloter M, Schmitt B, Schöning I, Schrumpf M, Sikorski J, Socher SA, Solly EF, Sonnemann I, Sorkau E, Steckel J, Steffan-Dewenter I, Stempfhuber B, Tschapka M, Türke M, Venter PC, Weiner CN, Weisser WW, Werner M, Westphal C, Wilcke W, Wolters V, Wubet T, Wurst S, Fischer M, Allan E.

Nature. 2016 Aug 25;536(7617):456-9. Epub 2016 Aug 17.

PMID:
27533038
21.

Natural Cubic Spline Regression Modeling Followed by Dynamic Network Reconstruction for the Identification of Radiation-Sensitivity Gene Association Networks from Time-Course Transcriptome Data.

Michna A, Braselmann H, Selmansberger M, Dietz A, Hess J, Gomolka M, Hornhardt S, Blüthgen N, Zitzelsberger H, Unger K.

PLoS One. 2016 Aug 9;11(8):e0160791. doi: 10.1371/journal.pone.0160791. eCollection 2016.

22.

Host specificity in a diverse Neotropical tick community: an assessment using quantitative network analysis and host phylogeny.

Esser HJ, Herre EA, Blüthgen N, Loaiza JR, Bermúdez SE, Jansen PA.

Parasit Vectors. 2016 Jun 29;9(1):372. doi: 10.1186/s13071-016-1655-6.

23.

Gene network activity in cultivated primary hepatocytes is highly similar to diseased mammalian liver tissue.

Godoy P, Widera A, Schmidt-Heck W, Campos G, Meyer C, Cadenas C, Reif R, Stöber R, Hammad S, Pütter L, Gianmoena K, Marchan R, Ghallab A, Edlund K, Nüssler A, Thasler WE, Damm G, Seehofer D, Weiss TS, Dirsch O, Dahmen U, Gebhardt R, Chaudhari U, Meganathan K, Sachinidis A, Kelm J, Hofmann U, Zahedi RP, Guthke R, Blüthgen N, Dooley S, Hengstler JG.

Arch Toxicol. 2016 Oct;90(10):2513-29. doi: 10.1007/s00204-016-1761-4. Epub 2016 Jun 23.

24.

Surface area-volume ratios in insects.

Kühsel S, Brückner A, Schmelzle S, Heethoff M, Blüthgen N.

Insect Sci. 2017 Oct;24(5):829-841. doi: 10.1111/1744-7917.12362. Epub 2016 Aug 15.

PMID:
27234132
25.

Locally rare species influence grassland ecosystem multifunctionality.

Soliveres S, Manning P, Prati D, Gossner MM, Alt F, Arndt H, Baumgartner V, Binkenstein J, Birkhofer K, Blaser S, Blüthgen N, Boch S, Böhm S, Börschig C, Buscot F, Diekötter T, Heinze J, Hölzel N, Jung K, Klaus VH, Klein AM, Kleinebecker T, Klemmer S, Krauss J, Lange M, Morris EK, Müller J, Oelmann Y, Overmann J, Pašalić E, Renner SC, Rillig MC, Schaefer HM, Schloter M, Schmitt B, Schöning I, Schrumpf M, Sikorski J, Socher SA, Solly EF, Sonnemann I, Sorkau E, Steckel J, Steffan-Dewenter I, Stempfhuber B, Tschapka M, Türke M, Venter P, Weiner CN, Weisser WW, Werner M, Westphal C, Wilcke W, Wolters V, Wubet T, Wurst S, Fischer M, Allan E.

Philos Trans R Soc Lond B Biol Sci. 2016 May 19;371(1694). pii: 20150269. doi: 10.1098/rstb.2015.0269.

26.

The relation between circadian asynchrony, functional redundancy, and trophic performance in tropical ant communities.

Houadria M, Blüthgen N, Salas-Lopez A, Schmitt MI, Arndt J, Schneider E, Orivel J, Menzel F.

Ecology. 2016 Jan;97(1):225-35.

PMID:
27008791
27.

Studying the Complex Communities of Ants and Their Symbionts Using Ecological Network Analysis.

Ivens AB, von Beeren C, Blüthgen N, Kronauer DJ.

Annu Rev Entomol. 2016;61:353-71. doi: 10.1146/annurev-ento-010715-023719. Review.

PMID:
26982442
28.

Stem Cell-Derived Immature Human Dorsal Root Ganglia Neurons to Identify Peripheral Neurotoxicants.

Hoelting L, Klima S, Karreman C, Grinberg M, Meisig J, Henry M, Rotshteyn T, Rahnenführer J, Blüthgen N, Sachinidis A, Waldmann T, Leist M.

Stem Cells Transl Med. 2016 Apr;5(4):476-87. doi: 10.5966/sctm.2015-0108. Epub 2016 Mar 1.

29.

Land use imperils plant and animal community stability through changes in asynchrony rather than diversity.

Blüthgen N, Simons NK, Jung K, Prati D, Renner SC, Boch S, Fischer M, Hölzel N, Klaus VH, Kleinebecker T, Tschapka M, Weisser WW, Gossner MM.

Nat Commun. 2016 Feb 12;7:10697. doi: 10.1038/ncomms10697.

30.

Effects of RAF inhibitors on PI3K/AKT signalling depend on mutational status of the RAS/RAF signalling axis.

Fritsche-Guenther R, Witzel F, Kempa S, Brummer T, Sers C, Blüthgen N.

Oncotarget. 2016 Feb 16;7(7):7960-9. doi: 10.18632/oncotarget.6959.

31.

Annexin A1 sustains tumor metabolism and cellular proliferation upon stable loss of HIF1A.

Rohwer N, Bindel F, Grimm C, Lin SJ, Wappler J, Klinger B, Blüthgen N, Du Bois I, Schmeck B, Lehrach H, de Graauw M, Goncalves E, Saez-Rodriguez J, Tan P, Grabsch HI, Prigione A, Kempa S, Cramer T.

Oncotarget. 2016 Feb 9;7(6):6693-710. doi: 10.18632/oncotarget.6793.

32.

Signaling output: it's all about timing and feedbacks.

Blüthgen N.

Mol Syst Biol. 2015 Nov 27;11(11):843. doi: 10.15252/msb.20156642.

33.

Landscape simplification filters species traits and drives biotic homogenization.

Gámez-Virués S, Perović DJ, Gossner MM, Börschig C, Blüthgen N, de Jong H, Simons NK, Klein AM, Krauss J, Maier G, Scherber C, Steckel J, Rothenwöhrer C, Steffan-Dewenter I, Weiner CN, Weisser W, Werner M, Tscharntke T, Westphal C.

Nat Commun. 2015 Oct 20;6:8568. doi: 10.1038/ncomms9568.

34.

A transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitors.

Rempel E, Hoelting L, Waldmann T, Balmer NV, Schildknecht S, Grinberg M, Das Gaspar JA, Shinde V, Stöber R, Marchan R, van Thriel C, Liebing J, Meisig J, Blüthgen N, Sachinidis A, Rahnenführer J, Hengstler JG, Leist M.

Arch Toxicol. 2015 Sep;89(9):1599-618. doi: 10.1007/s00204-015-1573-y. Epub 2015 Aug 14.

35.

High diversity stabilizes the thermal resilience of pollinator communities in intensively managed grasslands.

Kühsel S, Blüthgen N.

Nat Commun. 2015 Aug 10;6:7989. doi: 10.1038/ncomms8989.

36.

Grouping of histone deacetylase inhibitors and other toxicants disturbing neural crest migration by transcriptional profiling.

Dreser N, Zimmer B, Dietz C, Sügis E, Pallocca G, Nyffeler J, Meisig J, Blüthgen N, Berthold MR, Waldmann T, Leist M.

Neurotoxicology. 2015 Sep;50:56-70. doi: 10.1016/j.neuro.2015.07.008. Epub 2015 Jul 31.

PMID:
26238599
37.

RC3H1 post-transcriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-κB pathway.

Murakawa Y, Hinz M, Mothes J, Schuetz A, Uhl M, Wyler E, Yasuda T, Mastrobuoni G, Friedel CC, Dölken L, Kempa S, Schmidt-Supprian M, Blüthgen N, Backofen R, Heinemann U, Wolf J, Scheidereit C, Landthaler M.

Nat Commun. 2015 Jul 14;6:7367. doi: 10.1038/ncomms8367.

38.

Integrating network ecology with applied conservation: a synthesis and guide to implementation.

Kaiser-Bunbury CN, Blüthgen N.

AoB Plants. 2015 Jul 10;7. pii: plv076. doi: 10.1093/aobpla/plv076.

39.

Land use intensification alters ecosystem multifunctionality via loss of biodiversity and changes to functional composition.

Allan E, Manning P, Alt F, Binkenstein J, Blaser S, Blüthgen N, Böhm S, Grassein F, Hölzel N, Klaus VH, Kleinebecker T, Morris EK, Oelmann Y, Prati D, Renner SC, Rillig MC, Schaefer M, Schloter M, Schmitt B, Schöning I, Schrumpf M, Solly E, Sorkau E, Steckel J, Steffen-Dewenter I, Stempfhuber B, Tschapka M, Weiner CN, Weisser WW, Werner M, Westphal C, Wilcke W, Fischer M.

Ecol Lett. 2015 Aug;18(8):834-43. doi: 10.1111/ele.12469. Epub 2015 Jun 22.

40.

Bacterial computing with engineered populations.

Amos M, Axmann IM, Blüthgen N, de la Cruz F, Jaramillo A, Rodriguez-Paton A, Simmel F.

Philos Trans A Math Phys Eng Sci. 2015 Jul 28;373(2046). pii: 20140218. doi: 10.1098/rsta.2014.0218. Review.

41.

Tree Species Composition and Harvest Intensity Affect Herbivore Density and Leaf Damage on Beech, Fagus sylvatica, in Different Landscape Contexts.

Mangels J, Blüthgen N, Frank K, Grassein F, Hilpert A, Mody K.

PLoS One. 2015 May 4;10(5):e0126140. doi: 10.1371/journal.pone.0126140. eCollection 2015.

42.

Signal integration by the CYP1A1 promoter--a quantitative study.

Schulthess P, Löffler A, Vetter S, Kreft L, Schwarz M, Braeuning A, Blüthgen N.

Nucleic Acids Res. 2015 Jun 23;43(11):5318-30. doi: 10.1093/nar/gkv423. Epub 2015 May 1.

43.

Analysis of impedance-based cellular growth assays.

Witzel F, Fritsche-Guenther R, Lehmann N, Sieber A, Blüthgen N.

Bioinformatics. 2015 Aug 15;31(16):2705-12. doi: 10.1093/bioinformatics/btv216. Epub 2015 Apr 21.

PMID:
25900918
44.

Silence on the relevant literature and errors in implementation.

Bastiaens P, Birtwistle MR, Blüthgen N, Bruggeman FJ, Cho KH, Cosentino C, de la Fuente A, Hoek JB, Kiyatkin A, Klamt S, Kolch W, Legewie S, Mendes P, Naka T, Santra T, Sontag E, Westerhoff HV, Kholodenko BN.

Nat Biotechnol. 2015 Apr;33(4):336-9. doi: 10.1038/nbt.3185. No abstract available.

PMID:
25850052
45.

Gene expression. MicroRNA control of protein expression noise.

Schmiedel JM, Klemm SL, Zheng Y, Sahay A, Blüthgen N, Marks DS, van Oudenaarden A.

Science. 2015 Apr 3;348(6230):128-32. doi: 10.1126/science.aaa1738.

46.

Hypoxia-induced gene expression results from selective mRNA partitioning to the endoplasmic reticulum.

Staudacher JJ, Naarmann-de Vries IS, Ujvari SJ, Klinger B, Kasim M, Benko E, Ostareck-Lederer A, Ostareck DH, Bondke Persson A, Lorenzen S, Meier JC, Blüthgen N, Persson PB, Henrion-Caude A, Mrowka R, Fähling M.

Nucleic Acids Res. 2015 Mar 31;43(6):3219-36. doi: 10.1093/nar/gkv167. Epub 2015 Mar 8.

47.

Computer-assisted curation of a human regulatory core network from the biological literature.

Thomas P, Durek P, Solt I, Klinger B, Witzel F, Schulthess P, Mayer Y, Tikk D, Blüthgen N, Leser U.

Bioinformatics. 2015 Apr 15;31(8):1258-66. doi: 10.1093/bioinformatics/btu795. Epub 2014 Nov 29.

PMID:
25433699
48.

Consequences of feedback in signal transduction for targeted therapies.

Klinger B, Blüthgen N.

Biochem Soc Trans. 2014 Aug;42(4):770-5. doi: 10.1042/BST20140130. Review.

PMID:
25109956
49.

Tracking in vivo dynamics of NK cells transferred in patients undergoing stem cell transplantation.

Killig M, Friedrichs B, Meisig J, Gentilini C, Blüthgen N, Loddenkemper C, Labopin M, Basara N, Pfrepper C, Niederwieser DW, Uharek L, Romagnani C.

Eur J Immunol. 2014 Sep;44(9):2822-34. doi: 10.1002/eji.201444586. Epub 2014 Jun 30.

50.

Land-use impacts on plant-pollinator networks: interaction strength and specialization predict pollinator declines.

Weiner CN, Werner M, Linsenmair KE, Blüthgen N.

Ecology. 2014 Feb;95(2):466-74.

PMID:
24669739

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