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Items: 47


Chronic disease burden and frailty in survivors of childhood HSCT: a report from the St. Jude Lifetime Cohort Study.

Eissa HM, Lu L, Baassiri M, Bhakta N, Ehrhardt MJ, Triplett BM, Green DM, Mulrooney DA, Robison LL, Hudson MM, Ness KK.

Blood Adv. 2017 Nov 7;1(24):2243-2246. doi: 10.1182/bloodadvances.2017010280. eCollection 2017 Nov 14.


Blood Pressure Status in Adult Survivors of Childhood Cancer: A Report from the St. Jude Lifetime Cohort Study.

Gibson TM, Li Z, Green DM, Armstrong GT, Mulrooney DA, Srivastava D, Bhakta N, Ness KK, Hudson MM, Robison LL.

Cancer Epidemiol Biomarkers Prev. 2017 Dec;26(12):1705-1713. doi: 10.1158/1055-9965.EPI-17-0510. Epub 2017 Nov 22.


IFN-stimulated Gene Expression, Type 2 Inflammation, and Endoplasmic Reticulum Stress in Asthma.

Bhakta NR, Christenson SA, Nerella S, Solberg OD, Nguyen CP, Choy DF, Jung KL, Garudadri S, Bonser LR, Pollack JL, Zlock LT, Erle DJ, Langelier C, Derisi JL, Arron JR, Fahy JV, Woodruff PG.

Am J Respir Crit Care Med. 2018 Feb 1;197(3):313-324. doi: 10.1164/rccm.201706-1070OC.


Lesinurad monotherapy in gout patients intolerant to a xanthine oxidase inhibitor: a 6 month phase 3 clinical trial and extension study.

Tausche AK, Alten R, Dalbeth N, Kopicko J, Fung M, Adler S, Bhakta N, Storgard C, Baumgartner S, Saag K.

Rheumatology (Oxford). 2017 Dec 1;56(12):2170-2178. doi: 10.1093/rheumatology/kex350.


The cost and cost-effectiveness of childhood cancer treatment in El Salvador, Central America: A report from the Childhood Cancer 2030 Network.

Fuentes-Alabi S, Bhakta N, Vasquez RF, Gupta S, Horton SE.

Cancer. 2018 Jan 15;124(2):391-397. doi: 10.1002/cncr.31022. Epub 2017 Sep 15.


The cumulative burden of surviving childhood cancer: an initial report from the St Jude Lifetime Cohort Study (SJLIFE).

Bhakta N, Liu Q, Ness KK, Baassiri M, Eissa H, Yeo F, Chemaitilly W, Ehrhardt MJ, Bass J, Bishop MW, Shelton K, Lu L, Huang S, Li Z, Caron E, Lanctot J, Howell C, Folse T, Joshi V, Green DM, Mulrooney DA, Armstrong GT, Krull KR, Brinkman TM, Khan RB, Srivastava DK, Hudson MM, Yasui Y, Robison LL.

Lancet. 2017 Dec 9;390(10112):2569-2582. doi: 10.1016/S0140-6736(17)31610-0. Epub 2017 Sep 8.


Corticosteroid and long-acting ß-agonist therapy reduces epithelial goblet cell metaplasia.

Lachowicz-Scroggins ME, Finkbeiner WE, Gordon ED, Yuan S, Zlock L, Bhakta NR, Woodruff PG, Fahy JV, Boushey HA.

Clin Exp Allergy. 2017 Dec;47(12):1534-1545. doi: 10.1111/cea.13015. Epub 2017 Sep 26.


Natural killer cell-mediated inflammation resolution is disabled in severe asthma.

Duvall MG, Barnig C, Cernadas M, Ricklefs I, Krishnamoorthy N, Grossman NL, Bhakta NR, Fahy JV, Bleecker ER, Castro M, Erzurum SC, Gaston BM, Jarjour NN, Mauger DT, Wenzel SE, Comhair SA, Coverstone AM, Fajt ML, Hastie AT, Johansson MW, Peters MC, Phillips BR, Israel E, Levy BD; National Heart, Lung, and Blood Institute’s Severe Asthma Research Program-3 Investigators.

Sci Immunol. 2017 Mar 10;2(9). pii: eaam5446. doi: 10.1126/sciimmunol.aam5446.


More Than Meets the Eye: Cigarette Smoke Induces Genomic Changes in the Small Airway Epithelium Independent of Histologic Changes.

Bartel S, Bhakta N, Christenson S.

Am J Respir Crit Care Med. 2017 Aug 1;196(3):260-262. doi: 10.1164/rccm.201704-0665ED. No abstract available.


Lesinurad, a Selective Uric Acid Reabsorption Inhibitor, in Combination With Febuxostat in Patients With Tophaceous Gout: Findings of a Phase III Clinical Trial.

Dalbeth N, Jones G, Terkeltaub R, Khanna D, Kopicko J, Bhakta N, Adler S, Fung M, Storgard C, Baumgartner S, Perez-Ruiz F.

Arthritis Rheumatol. 2017 Sep;69(9):1903-1913. doi: 10.1002/art.40159. Epub 2017 Aug 4.


Opportunities for expanding clinical trial enrollment for relapsed and refractory pediatric acute myeloid leukemia in the United States and Canada.

Alexander TB, Bhakta N, Kolb EA, Rubnitz JE.

Pediatr Blood Cancer. 2017 Nov;64(11). doi: 10.1002/pbc.26632. Epub 2017 May 16. No abstract available.


The global burden of childhood cancer: Knowing what we do not know.

Frazier AL, Piñeros M, Fuentes S, Bhakta N.

Pediatr Blood Cancer. 2017 Aug;64(8). doi: 10.1002/pbc.26532. Epub 2017 Apr 14. No abstract available.


By Expanding the Color Palette, CO-Oximetry Overcomes Some, but Not All, of the Uncommon Limitations of Pulse Oximetry.

Bhakta NR.

Ann Am Thorac Soc. 2017 Apr;14(4):609. doi: 10.1513/AnnalsATS.201611-921LE. No abstract available.


Insights from Recognition of a Contradiction in the Equations that Define the Diffusing Capacity of the Lung for Carbon Monoxide.

Bhakta NR.

Ann Am Thorac Soc. 2017 Mar;14(3):473-474. doi: 10.1513/AnnalsATS.201611-920LE. No abstract available.


Grease fires turn up the heat in autoimmune disease.

Bhakta NR.

Sci Transl Med. 2017 Jan 25;9(374). pii: eaal4997. doi: 10.1126/scitranslmed.aal4997.


Approach for Classification and Severity Grading of Long-term and Late-Onset Health Events among Childhood Cancer Survivors in the St. Jude Lifetime Cohort.

Hudson MM, Ehrhardt MJ, Bhakta N, Baassiri M, Eissa H, Chemaitilly W, Green DM, Mulrooney DA, Armstrong GT, Brinkman TM, Klosky JL, Krull KR, Sabin ND, Wilson CL, Huang IC, Bass JK, Hale K, Kaste S, Khan RB, Srivastava DK, Yasui Y, Joshi VM, Srinivasan S, Stokes D, Hoehn ME, Wilson M, Ness KK, Robison LL.

Cancer Epidemiol Biomarkers Prev. 2017 May;26(5):666-674. doi: 10.1158/1055-9965.EPI-16-0812. Epub 2016 Dec 29. Review.


Effects of Age and Disease Severity on Systemic Corticosteroid Responses in Asthma.

Phipatanakul W, Mauger DT, Sorkness RL, Gaffin JM, Holguin F, Woodruff PG, Ly NP, Bacharier LB, Bhakta NR, Moore WC, Bleecker ER, Hastie AT, Meyers DA, Castro M, Fahy JV, Fitzpatrick AM, Gaston BM, Jarjour NN, Levy BD, Peters SP, Teague WG, Fajt M, Wenzel SE, Erzurum SC, Israel E; Severe Asthma Research Program.

Am J Respir Crit Care Med. 2017 Jun 1;195(11):1439-1448. doi: 10.1164/rccm.201607-1453OC.


Pitfalls of probiotics.

Bhakta NR.

Sci Transl Med. 2016 Dec 7;8(368):368ec194. No abstract available.


Late outcomes of adult survivors of childhood non-Hodgkin lymphoma: A report from the St. Jude Lifetime Cohort Study.

Ehrhardt MJ, Sandlund JT, Zhang N, Liu W, Ness KK, Bhakta N, Chemaitilly W, Krull KR, Brinkman TM, Crom DB, Kun L, Kaste SC, Armstrong GT, Green DM, Srivastava K, Robison LL, Hudson MM, Mulrooney DA.

Pediatr Blood Cancer. 2017 Jun;64(6). doi: 10.1002/pbc.26338. Epub 2016 Nov 15.


Features of the bronchial bacterial microbiome associated with atopy, asthma, and responsiveness to inhaled corticosteroid treatment.

Durack J, Lynch SV, Nariya S, Bhakta NR, Beigelman A, Castro M, Dyer AM, Israel E, Kraft M, Martin RJ, Mauger DT, Rosenberg SR, Sharp-King T, White SR, Woodruff PG, Avila PC, Denlinger LC, Holguin F, Lazarus SC, Lugogo N, Moore WC, Peters SP, Que L, Smith LJ, Sorkness CA, Wechsler ME, Wenzel SE, Boushey HA, Huang YJ; National Heart, Lung and Blood Institute's “AsthmaNet”.

J Allergy Clin Immunol. 2017 Jul;140(1):63-75. doi: 10.1016/j.jaci.2016.08.055. Epub 2016 Nov 10.


Lesinurad in combination with allopurinol: a randomised, double-blind, placebo-controlled study in patients with gout with inadequate response to standard of care (the multinational CLEAR 2 study).

Bardin T, Keenan RT, Khanna PP, Kopicko J, Fung M, Bhakta N, Adler S, Storgard C, Baumgartner S, So A.

Ann Rheum Dis. 2017 May;76(5):811-820. doi: 10.1136/annrheumdis-2016-209213. Epub 2016 Nov 7.


Lesinurad Combined With Allopurinol: A Randomized, Double-Blind, Placebo-Controlled Study in Gout Patients With an Inadequate Response to Standard-of-Care Allopurinol (a US-Based Study).

Saag KG, Fitz-Patrick D, Kopicko J, Fung M, Bhakta N, Adler S, Storgard C, Baumgartner S, Becker MA.

Arthritis Rheumatol. 2017 Jan;69(1):203-212. doi: 10.1002/art.39840.


Inflammatory and Comorbid Features of Patients with Severe Asthma and Frequent Exacerbations.

Denlinger LC, Phillips BR, Ramratnam S, Ross K, Bhakta NR, Cardet JC, Castro M, Peters SP, Phipatanakul W, Aujla S, Bacharier LB, Bleecker ER, Comhair SA, Coverstone A, DeBoer M, Erzurum SC, Fain SB, Fajt M, Fitzpatrick AM, Gaffin J, Gaston B, Hastie AT, Hawkins GA, Holguin F, Irani AM, Israel E, Levy BD, Ly N, Meyers DA, Moore WC, Myers R, Opina MT, Peters MC, Schiebler ML, Sorkness RL, Teague WG, Wenzel SE, Woodruff PG, Mauger DT, Fahy JV, Jarjour NN; National Heart, Lung, and Blood Institute’s Severe Asthma Research Program-3 Investigators.

Am J Respir Crit Care Med. 2017 Feb 1;195(3):302-313. doi: 10.1164/rccm.201602-0419OC.


Cumulative burden of cardiovascular morbidity in paediatric, adolescent, and young adult survivors of Hodgkin's lymphoma: an analysis from the St Jude Lifetime Cohort Study.

Bhakta N, Liu Q, Yeo F, Baassiri M, Ehrhardt MJ, Srivastava DK, Metzger ML, Krasin MJ, Ness KK, Hudson MM, Yasui Y, Robison LL.

Lancet Oncol. 2016 Sep;17(9):1325-34. doi: 10.1016/S1470-2045(16)30215-7. Epub 2016 Jul 25.


Pulmonary Function after Treatment for Childhood Cancer. A Report from the St. Jude Lifetime Cohort Study (SJLIFE).

Green DM, Zhu L, Wang M, Ness KK, Krasin MJ, Bhakta NH, McCarville MB, Srinivasan S, Stokes DC, Srivastava D, Ojha R, Shelton K, Pui CH, Armstrong GT, Mulrooney DA, Metzger M, Spunt SL, Navid F, Davidoff AM, Rao BN, Robison LL, Hudson MM.

Ann Am Thorac Soc. 2016 Sep;13(9):1575-85. doi: 10.1513/AnnalsATS.201601-022OC.


Absence of Basal Cell Carcinoma in Irradiated Childhood Cancer Survivors of Black Race: A Report from the St. Jude Lifetime Cohort Study.

Ehrhardt MJ, Bhakta N, Liu Q, Yasui Y, Krasin MJ, Mulrooney DA, Hudson MM, Robison LL.

Cancer Epidemiol Biomarkers Prev. 2016 Sep;25(9):1356-60. doi: 10.1158/1055-9965.EPI-16-0280. Epub 2016 Jun 30.


IFN-γ-Producing T-Helper 17.1 Cells Are Increased in Sarcoidosis and Are More Prevalent than T-Helper Type 1 Cells.

Ramstein J, Broos CE, Simpson LJ, Ansel KM, Sun SA, Ho ME, Woodruff PG, Bhakta NR, Christian L, Nguyen CP, Antalek BJ, Benn BS, Hendriks RW, van den Blink B, Kool M, Koth LL.

Am J Respir Crit Care Med. 2016 Jun 1;193(11):1281-91. doi: 10.1164/rccm.201507-1499OC.


Protein disulfide isomerase-endoplasmic reticulum resident protein 57 regulates allergen-induced airways inflammation, fibrosis, and hyperresponsiveness.

Hoffman SM, Chapman DG, Lahue KG, Cahoon JM, Rattu GK, Daphtary N, Aliyeva M, Fortner KA, Erzurum SC, Comhair SA, Woodruff PG, Bhakta N, Dixon AE, Irvin CG, Janssen-Heininger YM, Poynter ME, Anathy V.

J Allergy Clin Immunol. 2016 Mar;137(3):822-32.e7. doi: 10.1016/j.jaci.2015.08.018. Epub 2015 Oct 4.


Single-cell analysis reveals a stem-cell program in human metastatic breast cancer cells.

Lawson DA, Bhakta NR, Kessenbrock K, Prummel KD, Yu Y, Takai K, Zhou A, Eyob H, Balakrishnan S, Wang CY, Yaswen P, Goga A, Werb Z.

Nature. 2015 Oct 1;526(7571):131-5. doi: 10.1038/nature15260. Epub 2015 Sep 23.


A microRNA upregulated in asthma airway T cells promotes TH2 cytokine production.

Simpson LJ, Patel S, Bhakta NR, Choy DF, Brightbill HD, Ren X, Wang Y, Pua HH, Baumjohann D, Montoya MM, Panduro M, Remedios KA, Huang X, Fahy JV, Arron JR, Woodruff PG, Ansel KM.

Nat Immunol. 2014 Dec;15(12):1162-70. doi: 10.1038/ni.3026. Epub 2014 Nov 2.


IL-17 and "TH2-high" asthma: Adding fuel to the fire?

Bhakta NR, Erle DJ.

J Allergy Clin Immunol. 2014 Nov;134(5):1187-8. doi: 10.1016/j.jaci.2014.07.034. Epub 2014 Aug 28. No abstract available.


Longitudinal analysis of sarcoidosis blood transcriptomic signatures and disease outcomes.

Su R, Li MM, Bhakta NR, Solberg OD, Darnell EP, Ramstein J, Garudadri S, Ho M, Woodruff PG, Koth LL.

Eur Respir J. 2014 Oct;44(4):985-93. doi: 10.1183/09031936.00039714. Epub 2014 Aug 19.


Accumulation of BDCA1⁺ dendritic cells in interstitial fibrotic lung diseases and Th2-high asthma.

Greer AM, Matthay MA, Kukreja J, Bhakta NR, Nguyen CP, Wolters PJ, Woodruff PG, Fahy JV, Shin JS.

PLoS One. 2014 Jun 10;9(6):e99084. doi: 10.1371/journal.pone.0099084. eCollection 2014.


Measures of gene expression in sputum cells can identify TH2-high and TH2-low subtypes of asthma.

Peters MC, Mekonnen ZK, Yuan S, Bhakta NR, Woodruff PG, Fahy JV.

J Allergy Clin Immunol. 2014 Feb;133(2):388-94. doi: 10.1016/j.jaci.2013.07.036. Epub 2013 Sep 24.


A qPCR-based metric of Th2 airway inflammation in asthma.

Bhakta NR, Solberg OD, Nguyen CP, Nguyen CN, Arron JR, Fahy JV, Woodruff PG.

Clin Transl Allergy. 2013 Jul 17;3(1):24. doi: 10.1186/2045-7022-3-24.


Altered microRNA profiles in bronchoalveolar lavage fluid exosomes in asthmatic patients.

Levänen B, Bhakta NR, Torregrosa Paredes P, Barbeau R, Hiltbrunner S, Pollack JL, Sköld CM, Svartengren M, Grunewald J, Gabrielsson S, Eklund A, Larsson BM, Woodruff PG, Erle DJ, Wheelock ÅM.

J Allergy Clin Immunol. 2013 Mar;131(3):894-903. doi: 10.1016/j.jaci.2012.11.039. Epub 2013 Jan 16.


The cost effectiveness of treating paediatric cancer in low-income and middle-income countries: a case-study approach using acute lymphocytic leukaemia in Brazil and Burkitt lymphoma in Malawi.

Bhakta N, Martiniuk AL, Gupta S, Howard SC.

Arch Dis Child. 2013 Feb;98(2):155-60. doi: 10.1136/archdischild-2011-301419. Epub 2012 Nov 30.


Airway epithelial miRNA expression is altered in asthma.

Solberg OD, Ostrin EJ, Love MI, Peng JC, Bhakta NR, Hou L, Nguyen C, Solon M, Nguyen C, Barczak AJ, Zlock LT, Blagev DP, Finkbeiner WE, Ansel KM, Arron JR, Erle DJ, Woodruff PG.

Am J Respir Crit Care Med. 2012 Nov 15;186(10):965-74. doi: 10.1164/rccm.201201-0027OC. Epub 2012 Sep 6.


The relationship between CYP2C19 polymorphisms and ischaemic and bleeding outcomes in stable outpatients: the CHARISMA genetics study.

Bhatt DL, Paré G, Eikelboom JW, Simonsen KL, Emison ES, Fox KA, Steg PG, Montalescot G, Bhakta N, Hacke W, Flather MD, Mak KH, Cacoub P, Creager MA, Berger PB, Steinhubl SR, Murugesan G, Mehta SR, Kottke-Marchant K, Lincoff AM, Topol EJ; CHARISMA Investigators.

Eur Heart J. 2012 Sep;33(17):2143-50. Epub 2012 Mar 26.


Sarcoidosis blood transcriptome reflects lung inflammation and overlaps with tuberculosis.

Koth LL, Solberg OD, Peng JC, Bhakta NR, Nguyen CP, Woodruff PG.

Am J Respir Crit Care Med. 2011 Nov 15;184(10):1153-63. doi: 10.1164/rccm.201106-1143OC. Epub 2011 Aug 18.


Human asthma phenotypes: from the clinic, to cytokines, and back again.

Bhakta NR, Woodruff PG.

Immunol Rev. 2011 Jul;242(1):220-32. doi: 10.1111/j.1600-065X.2011.01032.x. Review.


Molecular mechanisms of paraptosis induction: implications for a non-genetically modified tumor vaccine.

Hoa N, Myers MP, Douglass TG, Zhang JG, Delgado C, Driggers L, Callahan LL, VanDeusen G, Pham JT, Bhakta N, Ge L, Jadus MR.

PLoS One. 2009;4(2):e4631. doi: 10.1371/journal.pone.0004631. Epub 2009 Feb 27.


Can pediatric steroid-free renal transplantation improve growth and metabolic complications?

Bhakta N, Marik J, Malekzadeh M, Gjertson D, Ettenger R.

Pediatr Transplant. 2008 Dec;12(8):854-61. doi: 10.1111/j.1399-3046.2008.00928.x. Epub 2008 May 14.


Real-time measurement of signaling and motility during T cell development in the thymus.

Bhakta NR, Lewis RS.

Semin Immunol. 2005 Dec;17(6):411-20. Epub 2005 Oct 25. Review.


Calcium oscillations regulate thymocyte motility during positive selection in the three-dimensional thymic environment.

Bhakta NR, Oh DY, Lewis RS.

Nat Immunol. 2005 Feb;6(2):143-51. Epub 2005 Jan 16.


Dynamics of thymocyte-stromal cell interactions visualized by two-photon microscopy.

Bousso P, Bhakta NR, Lewis RS, Robey E.

Science. 2002 Jun 7;296(5574):1876-80.


The insulin-like growth factors (IGFs) I and II bind to articular cartilage via the IGF-binding proteins.

Bhakta NR, Garcia AM, Frank EH, Grodzinsky AJ, Morales TI.

J Biol Chem. 2000 Feb 25;275(8):5860-6.

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