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Conformational changes of antibodies upon adsorption onto hydrophobic interaction chromatography surfaces.

Beyer B, Jungbauer A.

J Chromatogr A. 2018 Apr 5. pii: S0021-9673(18)30425-4. doi: 10.1016/j.chroma.2018.04.009. [Epub ahead of print]


Temperature dependence of antibody adsorption in protein A affinity chromatography.

Krepper W, Satzer P, Beyer BM, Jungbauer A.

J Chromatogr A. 2018 Mar 30. pii: S0021-9673(18)30386-8. doi: 10.1016/j.chroma.2018.03.059. [Epub ahead of print]


Return to work following robot-assisted laparoscopic and open retropubic radical prostatectomy: A single-center cohort study to compare duration of sick leave.

von Mechow S, Graefen M, Haese A, Tennstedt P, Pehrke D, Friedersdorff F, Beyer B.

Urol Oncol. 2018 Mar 15. pii: S1078-1439(18)30046-2. doi: 10.1016/j.urolonc.2018.02.006. [Epub ahead of print]


Multicenter evaluation of guideline adherence for pelvic lymph node dissection in patients undergoing open retropubic vs. laparoscopic or robot assisted radical prostatectomy according to the recent German S3 guideline on prostate cancer.

Borkowetz A, Bruendl J, Drerup M, Herrmann J, Isbarn H, Beyer B; GeSRU Academics Prostate Cancer Group.

World J Urol. 2018 Feb 9. doi: 10.1007/s00345-018-2195-9. [Epub ahead of print]


Morphometric changes of the cervical intervertebral foramen: A comparative analysis of pre-manipulative positioning and physiological axial rotation.

Dugailly PM, Beyer B, Salem W, Feipel V.

Musculoskelet Sci Pract. 2018 Apr;34:97-102. doi: 10.1016/j.msksp.2018.01.007. Epub 2018 Feb 6.


Metabolomics-based discovery of a metabolite that enhances oligodendrocyte maturation.

Beyer BA, Fang M, Sadrian B, Montenegro-Burke JR, Plaisted WC, Kok BPC, Saez E, Kondo T, Siuzdak G, Lairson LL.

Nat Chem Biol. 2018 Jan;14(1):22-28. doi: 10.1038/nchembio.2517. Epub 2017 Nov 13.


Mapping Protein Targets of Bioactive Small Molecules Using Lipid-Based Chemical Proteomics.

Lum KM, Sato Y, Beyer BA, Plaisted WC, Anglin JL, Lairson LL, Cravatt BF.

ACS Chem Biol. 2017 Oct 20;12(10):2671-2681. doi: 10.1021/acschembio.7b00581. Epub 2017 Sep 20.


In-vivo analysis of sternal angle, sternal and sternocostal kinematics in supine humans during breathing.

Beyer B, Feipel V, Sholukha V, Chèze L, Van Sint Jan S.

J Biomech. 2017 Nov 7;64:32-40. doi: 10.1016/j.jbiomech.2017.08.026. Epub 2017 Sep 1.


Short- and Long-term Functional Outcomes and Quality of Life after Radical Prostatectomy: Patient-reported Outcomes from a Tertiary High-volume Center.

Pompe RS, Tian Z, Preisser F, Tennstedt P, Beyer B, Michl U, Graefen M, Huland H, Karakiewicz PI, Tilki D.

Eur Urol Focus. 2017 Aug 28. pii: S2405-4569(17)30193-1. doi: 10.1016/j.euf.2017.08.001. [Epub ahead of print]


Microheterogeneity of Recombinant Antibodies: Analytics and Functional Impact.

Beyer B, Schuster M, Jungbauer A, Lingg N.

Biotechnol J. 2018 Jan;13(1). doi: 10.1002/biot.201700476. Epub 2017 Sep 25. Review.


Increased ERCC1 expression is linked to chromosomal aberrations and adverse tumor biology in prostate cancer.

Jacobsen F, Taskin B, Melling N, Sauer C, Wittmer C, Hube-Magg C, Kluth M, Simon R, Pehrke D, Beyer B, Steuber T, Thederan I, Sauter G, Schlomm T, Wilczak W, Möller K, Weidemann SA, Burdak-Rothkamm S.

BMC Cancer. 2017 Jul 26;17(1):504. doi: 10.1186/s12885-017-3489-9.


Zika Virus Infection in Patient with No Known Risk Factors, Utah, USA, 2016.

Krow-Lucal ER, Novosad SA, Dunn AC, Brent CR, Savage HM, Faraji A, Peterson D, Dibbs A, Vietor B, Christensen K, Laven JJ, Godsey MS Jr, Christensen B, Beyer B, Cortese MM, Johnson NC, Panella AJ, Biggerstaff BJ, Rubin M, Fridkin SK, Staples JE, Nakashima AK.

Emerg Infect Dis. 2017 Aug;23(8):1260-1267. doi: 10.3201/eid2308.170479.


Assessment of in vivo 3D kinematics of cervical spine manipulation: Influence of practitioner experience and occurrence of cavitation noise.

Van Geyt B, Dugailly PM, Klein P, Lepers Y, Beyer B, Feipel V.

Musculoskelet Sci Pract. 2017 Apr;28:18-24. doi: 10.1016/j.msksp.2017.01.002. Epub 2017 Jan 16.


Multidimensional Genetic Analysis of Repeated Seizures in the Hybrid Mouse Diversity Panel Reveals a Novel Epileptogenesis Susceptibility Locus.

Ferland RJ, Smith J, Papandrea D, Gracias J, Hains L, Kadiyala SB, O'Brien B, Kang EY, Beyer BS, Herron BJ.

G3 (Bethesda). 2017 Aug 7;7(8):2545-2558. doi: 10.1534/g3.117.042234.


Up regulation and nuclear translocation of Y-box binding protein 1 (YB-1) is linked to poor prognosis in ERG-negative prostate cancer.

Heumann A, Kaya Ö, Burdelski C, Hube-Magg C, Kluth M, Lang DS, Simon R, Beyer B, Thederan I, Sauter G, Izbicki JR, Luebke AM, Hinsch A, Jacobsen F, Wittmer C, Büscheck F, Höflmayer D, Minner S, Tsourlakis MC, Schlomm T, Wilczak W.

Sci Rep. 2017 May 17;7(1):2056. doi: 10.1038/s41598-017-02279-x.


Apurinic/apyrimidinic endonuclease 1 (APE1/Ref-1) overexpression is an independent prognostic marker in prostate cancer without TMPRSS2:ERG fusion.

Juhnke M, Heumann A, Chirico V, Höflmayer D, Menz A, Hinsch A, Hube-Magg C, Kluth M, Lang DS, Möller-Koop C, Sauter G, Simon R, Beyer B, Pompe R, Thederan I, Schlomm T, Luebke AM.

Mol Carcinog. 2017 Sep;56(9):2135-2145. doi: 10.1002/mc.22670. Epub 2017 May 22.


Small molecule-mediated inhibition of myofibroblast transdifferentiation for the treatment of fibrosis.

Bollong MJ, Yang B, Vergani N, Beyer BA, Chin EN, Zambaldo C, Wang D, Chatterjee AK, Lairson LL, Schultz PG.

Proc Natl Acad Sci U S A. 2017 May 2;114(18):4679-4684. doi: 10.1073/pnas.1702750114. Epub 2017 Apr 17.


How different are the Kebara 2 ribs to modern humans?

Chapman T, Beyer B, Sholukha V, Semal P, Feipel V, Louryan S, Van Sint Jan S.

J Anthropol Sci. 2017 Dec 30;95:183-201. doi: 10.4436/JASS.95004. Epub 2017 Mar 10.


Overexpression of the A Disintegrin and Metalloproteinase ADAM15 is linked to a Small but Highly Aggressive Subset of Prostate Cancers.

Burdelski C, Fitzner M, Hube-Magg C, Kluth M, Heumann A, Simon R, Krech T, Clauditz T, Büscheck F, Steurer S, Wittmer C, Hinsch A, Luebke AM, Jacobsen F, Minner S, Tsourlakis MC, Beyer B, Steuber T, Thederan I, Sauter G, Izbicki J, Schlomm T, Wilczak W.

Neoplasia. 2017 Apr;19(4):279-287. doi: 10.1016/j.neo.2017.01.005. Epub 2017 Mar 8.


Investigating the nucleic acid interactions of histone-derived antimicrobial peptides.

Sim S, Wang P, Beyer BN, Cutrona KJ, Radhakrishnan ML, Elmore DE.

FEBS Lett. 2017 Mar;591(5):706-717. doi: 10.1002/1873-3468.12574. Epub 2017 Mar 1.


Integrating Tertiary Gleason 5 Patterns into Quantitative Gleason Grading in Prostate Biopsies and Prostatectomy Specimens.

Sauter G, Clauditz T, Steurer S, Wittmer C, Büscheck F, Krech T, Lutz F, Lennartz M, Harms L, Lawrenz L, Möller-Koop C, Simon R, Jacobsen F, Wilczak W, Minner S, Tsourlakis MC, Chirico V, Weidemann S, Haese A, Steuber T, Salomon G, Matiu M, Vettorazzi E, Michl U, Budäus L, Tilki D, Thederan I, Pehrke D, Beyer B, Fraune C, Göbel C, Heinrich M, Juhnke M, Möller K, Bawahab AAA, Uhlig R, Huland H, Heinzer H, Graefen M, Schlomm T.

Eur Urol. 2018 May;73(5):674-683. doi: 10.1016/j.eururo.2017.01.015. Epub 2017 Jan 20.


Prognostic value of the new Grade Groups in Prostate Cancer: a multi-institutional European validation study.

Mathieu R, Moschini M, Beyer B, Gust KM, Seisen T, Briganti A, Karakiewicz P, Seitz C, Salomon L, de la Taille A, Rouprêt M, Graefen M, Shariat SF.

Prostate Cancer Prostatic Dis. 2017 Jun;20(2):197-202. doi: 10.1038/pcan.2016.66. Epub 2017 Jan 10.


Improved detection of circulating tumor cells in non-metastatic high-risk prostate cancer patients.

Kuske A, Gorges TM, Tennstedt P, Tiebel AK, Pompe R, Preißer F, Prues S, Mazel M, Markou A, Lianidou E, Peine S, Alix-Panabières C, Riethdorf S, Beyer B, Schlomm T, Pantel K.

Sci Rep. 2016 Dec 21;6:39736. doi: 10.1038/srep39736.


Prediction of the drilling path to surgically pin the femoral neck from the spatial location of pelvic and femoral anatomical landmarks: A cadaver validation study.

Sholukha V, Panda J, Salvia P, Beyer B, Rooze M, Jan SV.

Med Eng Phys. 2017 Feb;40:117-121. doi: 10.1016/j.medengphy.2016.11.008. Epub 2016 Dec 10.


Experience of collaboration between a Dutch surgical team in a Ghanaian Orthopaedic Teaching Hospital.

Timmers TK, Kortekaas E, Beyer B, Huizinga E, V Hezik van SM, Twagirayezu E, Bemelman M.

Afr Health Sci. 2016 Sep;16(3):838-844.


Functional Outcomes and Quality of Life After Radical Prostatectomy Only Versus a Combination of Prostatectomy with Radiation and Hormonal Therapy.

Adam M, Tennstedt P, Lanwehr D, Tilki D, Steuber T, Beyer B, Thederan I, Heinzer H, Haese A, Salomon G, Budäus L, Michl U, Pehrke D, Stattin P, Bernard J, Klaus B, Pompe RS, Petersen C, Huland H, Graefen M, Schwarz R, Huber W, Loeb S, Schlomm T.

Eur Urol. 2017 Mar;71(3):330-336. doi: 10.1016/j.eururo.2016.11.015. Epub 2016 Nov 22.


Deletion of 8p is an independent prognostic parameter in prostate cancer.

Kluth M, Amschler NN, Galal R, Möller-Koop C, Barrow P, Tsourlakis MC, Jacobsen F, Hinsch A, Wittmer C, Steurer S, Krech T, Büscheck F, Clauditz TS, Beyer B, Wilczak W, Graefen M, Huland H, Minner S, Schlomm T, Sauter G, Simon R.

Oncotarget. 2017 Jan 3;8(1):379-392. doi: 10.18632/oncotarget.13425.


Comparison of rat and rabbit embryo-fetal developmental toxicity data for 379 pharmaceuticals: on the nature and severity of developmental effects.

Theunissen PT, Beken S, Beyer BK, Breslin WJ, Cappon GD, Chen CL, Chmielewski G, De Schaepdrijver L, Enright B, Foreman JE, Harrouk W, Hew KW, Hoberman AM, Hui JY, Knudsen TB, Laffan SB, Makris SL, Martin M, McNerney ME, Siezen CL, Stanislaus DJ, Stewart J, Thompson KE, Tornesi B, Van der Laan JW, Weinbauer GF, Wood S, Piersma AH.

Crit Rev Toxicol. 2016 Nov;46(10):900-910. Epub 2016 Oct 19. Review.


p16 upregulation is linked to poor prognosis in ERG negative prostate cancer.

Burdelski C, Dieckmann T, Heumann A, Hube-Magg C, Kluth M, Beyer B, Steuber T, Pompe R, Graefen M, Simon R, Minner S, Tsourlakis MC, Koop C, Izbicki J, Sauter G, Krech T, Schlomm T, Wilczak W, Lebok P.

Tumour Biol. 2016 Sep;37(9):12655-12663. Epub 2016 Jul 21.


Comparing rat and rabbit embryo-fetal developmental toxicity data for 379 pharmaceuticals: on systemic dose and developmental effects.

Theunissen PT, Beken S, Beyer B, Breslin WJ, Cappon GD, Chen CL, Chmielewski G, de Schaepdrijver L, Enright B, Foreman JE, Harrouk W, Hew KW, Hoberman AM, Y Hui J, Knudsen TB, Laffan SB, Makris SL, Martin M, McNerney ME, Siezen CL, Stanislaus DJ, Stewart J, Thompson KE, Tornesi B, Van der Laan JW, Weinbauer GF, Wood S, Piersma AH.

Crit Rev Toxicol. 2017 May;47(5):402-414. doi: 10.1080/10408444.2016.1224808. Epub 2016 Oct 21.


[Primary Tumour Treatment in Patients with Metastatic Prostate Cancer].

Steuber T, Beyer B.

Aktuelle Urol. 2016 Sep;47(5):388-94. doi: 10.1055/s-0042-113547. Epub 2016 Sep 28. German.


Extended Intermolecular Interactions Governing Photocurrent-Voltage Relations in Ternary Organic Solar Cells.

Tress W, Beyer B, Ashari Astani N, Gao F, Meloni S, Rothlisberger U.

J Phys Chem Lett. 2016 Oct 6;7(19):3936-3944. Epub 2016 Sep 22.


Systemic Absorption of Catechins after Intraruminal or Intraduodenal Application of a Green Tea Extract in Cows.

Wein S, Beyer B, Gohlke A, Blank R, Metges CC, Wolffram S.

PLoS One. 2016 Jul 18;11(7):e0159428. doi: 10.1371/journal.pone.0159428. eCollection 2016.


Relationship between costovertebral joint kinematics and lung volume in supine humans.

Beyer B, Van Sint Jan S, Chèze L, Sholukha V, Feipel V.

Respir Physiol Neurobiol. 2016 Oct;232:57-65. doi: 10.1016/j.resp.2016.07.003. Epub 2016 Jul 12.


Eight Flurothyl-Induced Generalized Seizures Lead to the Rapid Evolution of Spontaneous Seizures in Mice: A Model of Epileptogenesis with Seizure Remission.

Kadiyala SB, Yannix JQ, Nalwalk JW, Papandrea D, Beyer BS, Herron BJ, Ferland RJ.

J Neurosci. 2016 Jul 13;36(28):7485-96. doi: 10.1523/JNEUROSCI.3232-14.2016.


Dynamin 1 isoform roles in a mouse model of severe childhood epileptic encephalopathy.

Asinof S, Mahaffey C, Beyer B, Frankel WN, Boumil R.

Neurobiol Dis. 2016 Nov;95:1-11. doi: 10.1016/j.nbd.2016.06.014. Epub 2016 Jun 28.


Band structure engineering in organic semiconductors.

Schwarze M, Tress W, Beyer B, Gao F, Scholz R, Poelking C, Ortstein K, Günther AA, Kasemann D, Andrienko D, Leo K.

Science. 2016 Jun 17;352(6292):1446-9. doi: 10.1126/science.aaf0590.


Birth Control in Clinical Trials: Industry Survey of Current Use Practices, Governance, and Monitoring.

Stewart J, Breslin WJ, Beyer BK, Chadwick K, De Schaepdrijver L, Desai M, Enright B, Foster W, Hui JY, Moffat GJ, Tornesi B, Van Malderen K, Wiesner L, Chen CL.

Ther Innov Regul Sci. 2016 Mar;50(2):155-168. Epub 2015 Oct 8.


Micro-CT imaging: Developing criteria for examining fetal skeletons in regulatory developmental toxicology studies - A workshop report.

Solomon HM, Makris SL, Alsaid H, Bermudez O, Beyer BK, Chen A, Chen CL, Chen Z, Chmielewski G, DeLise AM, de Schaepdrijver L, Dogdas B, French J, Harrouk W, Helfgott J, Henkelman RM, Hesterman J, Hew KW, Hoberman A, Lo CW, McDougal A, Minck DR, Scott L, Stewart J, Sutherland V, Tatiparthi AK, Winkelmann CT, Wise LD, Wood SL, Ying X.

Regul Toxicol Pharmacol. 2016 Jun;77:100-8. doi: 10.1016/j.yrtph.2016.02.018. Epub 2016 Feb 27.


Intermediate-term cancer control outcomes in prostate cancer patients treated with robotic-assisted laparoscopic radical prostatectomy: a multi-institutional analysis.

Abdollah F, Dalela D, Sood A, Sammon J, Jeong W, Beyer B, Fossati N, Rogers CG, Diaz-Insua M, Peabody J, Haese A, Montorsi F, Graefen M, Briganti A, Menon M.

World J Urol. 2016 Oct;34(10):1357-66. doi: 10.1007/s00345-016-1781-y. Epub 2016 Feb 12.


Reprint of "Potential seminal transport of pharmaceuticals to the conceptus".

Scialli AR, Bailey G, Beyer BK, Bøgh IB, Breslin WJ, Chen CL, DeLise AM, Hui JY, Moffat GJ, Stewart J, Thompson KE.

Reprod Toxicol. 2016 Jan;59:22-30. doi: 10.1016/j.reprotox.2016.01.005. Epub 2016 Feb 6. Review.


Differences in Patient Characteristics Among Men Choosing Open or Robot-Assisted Radical Prostatectomy in Contemporary Practice at a European High-Volume Center.

Schiffmann J, Haese A, Lenz J, Heinzer H, Salomon G, Steuber T, Beyer B, Boehm K, Tilki D, Michl U, Tennstedt P, Huland H, Graefen M, Karakiewicz PI.

Urol Int. 2016;97(1):8-15. doi: 10.1159/000443701. Epub 2016 Jan 19.


Oncological, functional and perioperative outcomes in transplant patients after radical prostatectomy.

Beyer B, Mandel P, Michl U, Pompe RS, Veleva V, Steuber T, Huland H, Graefen M, Tilki D.

World J Urol. 2016 Aug;34(8):1101-5. doi: 10.1007/s00345-015-1758-2. Epub 2016 Jan 12.


Characterization of 137 Genomic DNA Reference Materials for 28 Pharmacogenetic Genes: A GeT-RM Collaborative Project.

Pratt VM, Everts RE, Aggarwal P, Beyer BN, Broeckel U, Epstein-Baak R, Hujsak P, Kornreich R, Liao J, Lorier R, Scott SA, Smith CH, Toji LH, Turner A, Kalman LV.

J Mol Diagn. 2016 Jan;18(1):109-23. doi: 10.1016/j.jmoldx.2015.08.005. Epub 2015 Nov 24.


[Systematic analysis of treatment results as a quality control instrument using the example of a large European center].

Beyer B, Huland H, Graefen M.

Urologe A. 2015 Nov;54(11):1537-8, 1540-5. doi: 10.1007/s00120-015-3836-x. German.


Potential seminal transport of pharmaceuticals to the conceptus.

Scialli AR, Bailey G, Beyer BK, Bøgh IB, Breslin WJ, Chen CL, DeLise AM, Hui JY, Moffat GJ, Stewart J, Thompson KE.

Reprod Toxicol. 2015 Dec;58:213-21. doi: 10.1016/j.reprotox.2015.10.015. Epub 2015 Nov 3. Review.


Clinical Utility of Quantitative Gleason Grading in Prostate Biopsies and Prostatectomy Specimens.

Sauter G, Steurer S, Clauditz TS, Krech T, Wittmer C, Lutz F, Lennartz M, Janssen T, Hakimi N, Simon R, von Petersdorff-Campen M, Jacobsen F, von Loga K, Wilczak W, Minner S, Tsourlakis MC, Chirico V, Haese A, Heinzer H, Beyer B, Graefen M, Michl U, Salomon G, Steuber T, Budäus LH, Hekeler E, Malsy-Mink J, Kutzera S, Fraune C, Göbel C, Huland H, Schlomm T.

Eur Urol. 2016 Apr;69(4):592-8. doi: 10.1016/j.eururo.2015.10.029. Epub 2015 Nov 2.


Additional elastography-targeted biopsy improves the agreement between biopsy Gleason grade and Gleason grade at radical prostatectomy.

Boehm K, Tennstedt P, Beyer B, Schiffmann J, Beckmann A, Michl U, Beyersdorff D, Budäus L, Graefen M, Karakiewicz PI, Salomon G.

World J Urol. 2016 Jun;34(6):805-10. doi: 10.1007/s00345-015-1714-1. Epub 2015 Oct 19.


When Should a Positive Surgical Margin Ring a Bell? An Analysis of a Multi-Institutional Robot-Assisted Laparoscopic Radical Prostatectomy Database.

Abdollah F, Moschini M, Sood A, Sammon J, Dalela D, Hsu L, Beyer B, Haese A, Graefen M, Gandaglia G, Montorsi F, Briganti A, Menon M.

J Endourol. 2016 Feb;30(2):201-7. doi: 10.1089/end.2015.0465. Epub 2015 Oct 8.


["Expanded prostate cancer index composite" (EPIC-26): Results of functional treatment in patients with localized prostate cancer].

Beyer B, Huland H, Feick G, Graefen M.

Urologe A. 2015 Nov;54(11):1591-5. doi: 10.1007/s00120-015-3922-0. German.


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