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Items: 31


Matrix metalloproteinase 12 promotes tumor propagation in the lung.

Ella E, Harel Y, Abraham M, Wald H, Benny O, Karsch-Bluman A, Vincent D, Laurent D, Amir G, Izhar U, Shapira OM, Yoon D, Lee HS, Sugarbaker DJ, Burt B, Peled A, Wald O.

J Thorac Cardiovasc Surg. 2018 Feb 8. pii: S0022-5223(18)30069-2. doi: 10.1016/j.jtcvs.2017.11.110. [Epub ahead of print]


Nerve Growth Factor-Induced Angiogenesis: 1. Endothelial Cell Tube Formation Assay.

Lazarovici P, Lahiani A, Gincberg G, Haham D, Fluksman A, Benny O, Marcinkiewicz C, Lelkes PI.

Methods Mol Biol. 2018;1727:239-250. doi: 10.1007/978-1-4939-7571-6_18.


Evolving multidimensional pharmacological approaches to CNV therapy in AMD.

Ehrenberg M, Benny O.

Curr Eye Res. 2018 Feb;43(2):147-154. doi: 10.1080/02713683.2017.1385088. Epub 2017 Nov 7.


Tumor cells and their crosstalk with endothelial cells in 3D spheroids.

Shoval H, Karsch-Bluman A, Brill-Karniely Y, Stern T, Zamir G, Hubert A, Benny O.

Sci Rep. 2017 Sep 5;7(1):10428. doi: 10.1038/s41598-017-10699-y.


High mobility group box 1 antagonist limits metastatic seeding in the lungs via reduction of cell-cell adhesion.

Karsch-Bluman A, Amoyav B, Friedman N, Shoval H, Schwob O, Ella E, Wald O, Benny O.

Oncotarget. 2017 May 16;8(20):32706-32721. doi: 10.18632/oncotarget.16188.


Rigidity of polymer micelles affects interactions with tumor cells.

Stern T, Kaner I, Laser Zer N, Shoval H, Dror D, Manevitch Z, Chai L, Brill-Karniely Y, Benny O.

J Control Release. 2017 Jul 10;257:40-50. doi: 10.1016/j.jconrel.2016.12.013. Epub 2016 Dec 23.


VEGF preconditioning leads to stem cell remodeling and attenuates age-related decay of adult hippocampal neurogenesis.

Licht T, Rothe G, Kreisel T, Wolf B, Benny O, Rooney AG, Ffrench-Constant C, Enikolopov G, Keshet E.

Proc Natl Acad Sci U S A. 2016 Nov 29;113(48):E7828-E7836. Epub 2016 Nov 14.


Murine fundus fluorescein angiography: An alternative approach using a handheld camera.

Ehrenberg M, Ehrenberg S, Schwob O, Benny O.

Exp Eye Res. 2016 Jul;148:74-78. doi: 10.1016/j.exer.2016.05.024. Epub 2016 May 31.


Cellular mechanism of oral absorption of solidified polymer micelles.

Abramov E, Cassiola F, Schwob O, Karsh-Bluman A, Shapero M, Ellis J, Luyindula D, Adini I, D'Amato RJ, Benny O.

Nanomedicine. 2015 Nov;11(8):1993-2002. doi: 10.1016/j.nano.2015.07.008. Epub 2015 Aug 3.


The corneal micropocket assay: a model of angiogenesis in the mouse eye.

Birsner AE, Benny O, D'Amato RJ.

J Vis Exp. 2014 Aug 16;(90). doi: 10.3791/51375.


Vimocin and vidapin, cyclic KTS peptides, are dual antagonists of α1β1/α2β1 integrins with antiangiogenic activity.

Momic T, Katzehendler J, Benny O, Lahiani A, Cohen G, Noy E, Senderowitz H, Eble JA, Marcinkiewicz C, Lazarovici P.

J Pharmacol Exp Ther. 2014 Sep;350(3):506-19. doi: 10.1124/jpet.114.214643. Epub 2014 Jun 17.


Melanocyte-secreted fibromodulin promotes an angiogenic microenvironment.

Adini I, Ghosh K, Adini A, Chi ZL, Yoshimura T, Benny O, Connor KM, Rogers MS, Bazinet L, Birsner AE, Bielenberg DR, D'Amato RJ.

J Clin Invest. 2014 Jan;124(1):425-36. doi: 10.1172/JCI69404. Epub 2013 Dec 20.


Epoxyeicosanoids promote organ and tissue regeneration.

Panigrahy D, Kalish BT, Huang S, Bielenberg DR, Le HD, Yang J, Edin ML, Lee CR, Benny O, Mudge DK, Butterfield CE, Mammoto A, Mammoto T, Inceoglu B, Jenkins RL, Simpson MA, Akino T, Lih FB, Tomer KB, Ingber DE, Hammock BD, Falck JR, Manthati VL, Kaipainen A, D'Amore PA, Puder M, Zeldin DC, Kieran MW.

Proc Natl Acad Sci U S A. 2013 Aug 13;110(33):13528-33. doi: 10.1073/pnas.1311565110. Epub 2013 Jul 29.


Suppression of autoimmune retinal inflammation by an antiangiogenic drug.

Yoshimura T, Benny O, Bazinet L, D'Amato RJ.

PLoS One. 2013 Jun 13;8(6):e66219. doi: 10.1371/journal.pone.0066219. Print 2013.


The stem cell marker prominin-1/CD133 interacts with vascular endothelial growth factor and potentiates its action.

Adini A, Adini I, Ghosh K, Benny O, Pravda E, Hu R, Luyindula D, D'Amato RJ.

Angiogenesis. 2013 Apr;16(2):405-16. doi: 10.1007/s10456-012-9323-8. Epub 2012 Nov 13.


Epoxyeicosanoids stimulate multiorgan metastasis and tumor dormancy escape in mice.

Panigrahy D, Edin ML, Lee CR, Huang S, Bielenberg DR, Butterfield CE, Barnés CM, Mammoto A, Mammoto T, Luria A, Benny O, Chaponis DM, Dudley AC, Greene ER, Vergilio JA, Pietramaggiori G, Scherer-Pietramaggiori SS, Short SM, Seth M, Lih FB, Tomer KB, Yang J, Schwendener RA, Hammock BD, Falck JR, Manthati VL, Ingber DE, Kaipainen A, D'Amore PA, Kieran MW, Zeldin DC.

J Clin Invest. 2012 Jan;122(1):178-91. doi: 10.1172/JCI58128. Epub 2011 Dec 19.


Circulating endothelial progenitor cells are up-regulated in a mouse model of endometriosis.

Becker CM, Beaudry P, Funakoshi T, Benny O, Zaslavsky A, Zurakowski D, Folkman J, D'Amato RJ, Ryeom S.

Am J Pathol. 2011 Apr;178(4):1782-91. doi: 10.1016/j.ajpath.2010.12.037.


Broad spectrum antiangiogenic treatment for ocular neovascular diseases.

Benny O, Nakai K, Yoshimura T, Bazinet L, Akula JD, Nakao S, Hafezi-Moghadam A, Panigrahy D, Pakneshan P, D'Amato RJ.

PLoS One. 2010 Sep 1;5(9). pii: e12515. doi: 10.1371/journal.pone.0012515.


Novel local drug delivery system using thermoreversible gel in combination with polymeric microspheres or liposomes.

Arai T, Benny O, Joki T, Menon LG, Machluf M, Abe T, Carroll RS, Black PM.

Anticancer Res. 2010 Apr;30(4):1057-64.


Alginate-PLL cell encapsulation system Co-entrapping PLGA-microspheres for the continuous release of anti-inflammatory drugs.

Baruch L, Benny O, Gilert A, Ukobnik M, Ben Itzhak O, Machluf M.

Biomed Microdevices. 2009 Oct;11(5):1103-13. doi: 10.1007/s10544-009-9327-3. Epub 2009 Jun 11.


Novel technologies for antiangiogenic drug delivery in the brain.

Benny O, Pakneshan P.

Cell Adh Migr. 2009 Apr-Jun;3(2):224-9. Epub 2009 Apr 6. Review.


Local delivery of poly lactic-co-glycolic acid microspheres containing imatinib mesylate inhibits intracranial xenograft glioma growth.

Benny O, Menon LG, Ariel G, Goren E, Kim SK, Stewman C, Black PM, Carroll RS, Machluf M.

Clin Cancer Res. 2009 Feb 15;15(4):1222-31. doi: 10.1158/1078-0432.CCR-08-1316. Epub 2009 Feb 3.


Doxycycline induces membrane expression of VE-cadherin on endothelial cells and prevents vascular hyperpermeability.

Fainaru O, Adini I, Benny O, Bazinet L, Pravda E, D'Amato R, Folkman J.

FASEB J. 2008 Oct;22(10):3728-35. doi: 10.1096/fj.08-110494. Epub 2008 Jul 7.


An orally delivered small-molecule formulation with antiangiogenic and anticancer activity.

Benny O, Fainaru O, Adini A, Cassiola F, Bazinet L, Adini I, Pravda E, Nahmias Y, Koirala S, Corfas G, D'Amato RJ, Folkman J.

Nat Biotechnol. 2008 Jul;26(7):799-807. doi: 10.1038/nbt1415. Epub 2008 Jun 29.


Dendritic cells augment choroidal neovascularization.

Nakai K, Fainaru O, Bazinet L, Pakneshan P, Benny O, Pravda E, Folkman J, D'Amato RJ.

Invest Ophthalmol Vis Sci. 2008 Aug;49(8):3666-70. doi: 10.1167/iovs.07-1640. Epub 2008 Apr 11.


In vivo fate and therapeutic efficacy of PF-4/CTF microspheres in an orthotopic human glioblastoma model.

Benny O, Kim SK, Gvili K, Radzishevsky IS, Mor A, Verduzco L, Menon LG, Black PM, Machluf M, Carroll RS.

FASEB J. 2008 Feb;22(2):488-99. Epub 2007 Sep 14.


Dendritic cells support angiogenesis and promote lesion growth in a murine model of endometriosis.

Fainaru O, Adini A, Benny O, Adini I, Short S, Bazinet L, Nakai K, Pravda E, Hornstein MD, D'Amato RJ, Folkman J.

FASEB J. 2008 Feb;22(2):522-9. Epub 2007 Sep 14.


Therapeutic ultrasound facilitates antiangiogenic gene delivery and inhibits prostate tumor growth.

Duvshani-Eshet M, Benny O, Morgenstern A, Machluf M.

Mol Cancer Ther. 2007 Aug;6(8):2371-82.


Poly(D,L-lactide-co-glycolide acid) nanoparticles for DNA delivery: waiving preparation complexity and increasing efficiency.

Gvili K, Benny O, Danino D, Machluf M.

Biopolymers. 2007 Apr 5-15;85(5-6):379-91.


Continuous delivery of endogenous inhibitors from poly(lactic-co-glycolic acid) polymeric microspheres inhibits glioma tumor growth.

Benny O, Duvshani-Eshet M, Cargioli T, Bello L, Bikfalvi A, Carroll RS, Machluf M.

Clin Cancer Res. 2005 Jan 15;11(2 Pt 1):768-76.


A fail-safe mechanism for negative selection of isotype-switched B cell precursors is regulated by the Fas/FasL pathway.

Seagal J, Edry E, Keren Z, Leider N, Benny O, Machluf M, Melamed D.

J Exp Med. 2003 Nov 17;198(10):1609-19.

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