Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 38

1.

Identification and characterization of HIV-specific resident memory CD8+ T cells in human lymphoid tissue.

Buggert M, Nguyen S, Salgado-Montes de Oca G, Bengsch B, Darko S, Ransier A, Roberts ER, Del Alcazar D, Brody IB, Vella LA, Beura L, Wijeyesinghe S, Herati RS, Del Rio Estrada PM, Ablanedo-Terrazas Y, Kuri-Cervantes L, Sada Japp A, Manne S, Vartanian S, Huffman A, Sandberg JK, Gostick E, Nadolski G, Silvestri G, Canaday DH, Price DA, Petrovas C, Su LF, Vahedi G, Dori Y, Frank I, Itkin MG, Wherry EJ, Deeks SG, Naji A, Reyes-Terán G, Masopust D, Douek DC, Betts MR.

Sci Immunol. 2018 Jun 1;3(24). pii: eaar4526. doi: 10.1126/sciimmunol.aar4526.

PMID:
29858286
2.

Epigenomic-Guided Mass Cytometry Profiling Reveals Disease-Specific Features of Exhausted CD8 T Cells.

Bengsch B, Ohtani T, Khan O, Setty M, Manne S, O'Brien S, Gherardini PF, Herati RS, Huang AC, Chang KM, Newell EW, Bovenschen N, Pe'er D, Albelda SM, Wherry EJ.

Immunity. 2018 May 15;48(5):1029-1045.e5. doi: 10.1016/j.immuni.2018.04.026.

PMID:
29768164
3.

Outcome of anti-viral immunity in the liver is shaped by the level of antigen expressed in infected hepatocytes.

Manske K, Kallin N, König V, Schneider A, Kurz S, Bosch M, Welz M, Cheng RL, Bengsch B, Steiger K, Protzer U, Thimme R, Knolle PA, Wohlleber D.

Hepatology. 2018 May 5. doi: 10.1002/hep.30080. [Epub ahead of print]

PMID:
29729204
4.

For whom the interferons toll - TLR7 mediated boosting of innate and adaptive immunity against chronic HBV infection.

Bengsch B, Thimme R.

J Hepatol. 2018 May;68(5):883-886. doi: 10.1016/j.jhep.2018.01.025. Epub 2018 Mar 3. No abstract available.

PMID:
29408443
5.

Differentiation and Protective Capacity of Virus-Specific CD8+ T Cells Suggest Murine Norovirus Persistence in an Immune-Privileged Enteric Niche.

Tomov VT, Palko O, Lau CW, Pattekar A, Sun Y, Tacheva R, Bengsch B, Manne S, Cosma GL, Eisenlohr LC, Nice TJ, Virgin HW, Wherry EJ.

Immunity. 2017 Oct 17;47(4):723-738.e5. doi: 10.1016/j.immuni.2017.09.017. Epub 2017 Oct 11.

PMID:
29031786
6.

Optimized retroviral transduction of mouse T cells for in vivo assessment of gene function.

Kurachi M, Kurachi J, Chen Z, Johnson J, Khan O, Bengsch B, Stelekati E, Attanasio J, McLane LM, Tomura M, Ueha S, Wherry EJ.

Nat Protoc. 2017 Sep;12(9):1980-1998. doi: 10.1038/nprot.2017.083. Epub 2017 Aug 31.

PMID:
28858287
7.

Successive annual influenza vaccination induces a recurrent oligoclonotypic memory response in circulating T follicular helper cells.

Herati RS, Muselman A, Vella L, Bengsch B, Parkhouse K, Del Alcazar D, Kotzin J, Doyle SA, Tebas P, Hensley SE, Su LF, Schmader KE, Wherry EJ.

Sci Immunol. 2017 Feb;2(8). pii: eaag2152. doi: 10.1126/sciimmunol.aag2152. Epub 2017 Feb 17.

8.

Protein-losing pseudomembranous colitis with cap polyposis-like features.

Kreisel W, Ruf G, Salm R, Lazaro A, Bengsch B, Globig AM, Fisch P, Lassmann S, Schmitt-Graeff A.

World J Gastroenterol. 2017 Apr 28;23(16):3003-3010. doi: 10.3748/wjg.v23.i16.3003.

9.

T-cell invigoration to tumour burden ratio associated with anti-PD-1 response.

Huang AC, Postow MA, Orlowski RJ, Mick R, Bengsch B, Manne S, Xu W, Harmon S, Giles JR, Wenz B, Adamow M, Kuk D, Panageas KS, Carrera C, Wong P, Quagliarello F, Wubbenhorst B, D'Andrea K, Pauken KE, Herati RS, Staupe RP, Schenkel JM, McGettigan S, Kothari S, George SM, Vonderheide RH, Amaravadi RK, Karakousis GC, Schuchter LM, Xu X, Nathanson KL, Wolchok JD, Gangadhar TC, Wherry EJ.

Nature. 2017 May 4;545(7652):60-65. doi: 10.1038/nature22079. Epub 2017 Apr 10.

10.

Deep immune profiling by mass cytometry links human T and NK cell differentiation and cytotoxic molecule expression patterns.

Bengsch B, Ohtani T, Herati RS, Bovenschen N, Chang KM, Wherry EJ.

J Immunol Methods. 2018 Feb;453:3-10. doi: 10.1016/j.jim.2017.03.009. Epub 2017 Mar 19.

11.

Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade.

Pauken KE, Sammons MA, Odorizzi PM, Manne S, Godec J, Khan O, Drake AM, Chen Z, Sen DR, Kurachi M, Barnitz RA, Bartman C, Bengsch B, Huang AC, Schenkel JM, Vahedi G, Haining WN, Berger SL, Wherry EJ.

Science. 2016 Dec 2;354(6316):1160-1165. Epub 2016 Oct 27.

12.

Evolution in Our Understanding of Hepatitis B Virus Virology and Immunology.

Bengsch B, Chang KM.

Clin Liver Dis. 2016 Nov;20(4):629-644. doi: 10.1016/j.cld.2016.06.001. Epub 2016 Aug 12. Review.

PMID:
27742004
13.

Bioenergetic Insufficiencies Due to Metabolic Alterations Regulated by the Inhibitory Receptor PD-1 Are an Early Driver of CD8(+) T Cell Exhaustion.

Bengsch B, Johnson AL, Kurachi M, Odorizzi PM, Pauken KE, Attanasio J, Stelekati E, McLane LM, Paley MA, Delgoffe GM, Wherry EJ.

Immunity. 2016 Aug 16;45(2):358-73. doi: 10.1016/j.immuni.2016.07.008. Epub 2016 Aug 2.

14.

Cutting Edge: IL-4, IL-21, and IFN-γ Interact To Govern T-bet and CD11c Expression in TLR-Activated B Cells.

Naradikian MS, Myles A, Beiting DP, Roberts KJ, Dawson L, Herati RS, Bengsch B, Linderman SL, Stelekati E, Spolski R, Wherry EJ, Hunter C, Hensley SE, Leonard WJ, Cancro MP.

J Immunol. 2016 Aug 15;197(4):1023-8. doi: 10.4049/jimmunol.1600522. Epub 2016 Jul 18.

15.

The importance of cooperation: partnerless NFAT induces T cell exhaustion.

Bengsch B, Wherry EJ.

Immunity. 2015 Feb 17;42(2):203-205. doi: 10.1016/j.immuni.2015.01.023.

16.

Comprehensive intestinal T helper cell profiling reveals specific accumulation of IFN-γ+IL-17+coproducing CD4+ T cells in active inflammatory bowel disease.

Globig AM, Hennecke N, Martin B, Seidl M, Ruf G, Hasselblatt P, Thimme R, Bengsch B.

Inflamm Bowel Dis. 2014 Dec;20(12):2321-9. doi: 10.1097/MIB.0000000000000210.

PMID:
25248005
17.

Dysfunctional CD8+ T cells in hepatitis B and C are characterized by a lack of antigen-specific T-bet induction.

Kurktschiev PD, Raziorrouh B, Schraut W, Backmund M, Wächtler M, Wendtner CM, Bengsch B, Thimme R, Denk G, Zachoval R, Dick A, Spannagl M, Haas J, Diepolder HM, Jung MC, Gruener NH.

J Exp Med. 2014 Sep 22;211(10):2047-59. doi: 10.1084/jem.20131333. Epub 2014 Sep 15.

18.

Inhibitory phenotype of HBV-specific CD4+ T-cells is characterized by high PD-1 expression but absent coregulation of multiple inhibitory molecules.

Raziorrouh B, Heeg M, Kurktschiev P, Schraut W, Zachoval R, Wendtner C, Wächtler M, Spannagl M, Denk G, Ulsenheimer A, Bengsch B, Pircher H, Diepolder HM, Grüner NH, Jung MC.

PLoS One. 2014 Aug 21;9(8):e105703. doi: 10.1371/journal.pone.0105703. eCollection 2014.

19.

Restoration of HBV-specific CD8+ T cell function by PD-1 blockade in inactive carrier patients is linked to T cell differentiation.

Bengsch B, Martin B, Thimme R.

J Hepatol. 2014 Dec;61(6):1212-9. doi: 10.1016/j.jhep.2014.07.005. Epub 2014 Jul 10.

PMID:
25016223
20.

Abnormally differentiated CD4+ or CD8+ T cells with phenotypic and genetic features of double negative T cells in human Fas deficiency.

Rensing-Ehl A, Völkl S, Speckmann C, Lorenz MR, Ritter J, Janda A, Abinun M, Pircher H, Bengsch B, Thimme R, Fuchs I, Ammann S, Allgäuer A, Kentouche K, Cant A, Hambleton S, Bettoni da Cunha C, Huetker S, Kühnle I, Pekrun A, Seidel MG, Hummel M, Mackensen A, Schwarz K, Ehl S.

Blood. 2014 Aug 7;124(6):851-60. doi: 10.1182/blood-2014-03-564286. Epub 2014 Jun 3.

21.

Balance lost: T cell immunity in progressive HBV infection.

Bengsch B, Thimme R.

Hepatol Int. 2014 Jan;8(1):7-9. doi: 10.1007/s12072-013-9506-4. Epub 2014 Jan 9. No abstract available.

PMID:
26202401
22.

[Serologic pitfalls in the diagnosis of hepatopathy of uncertain origin].

Bengsch B, Thimme R.

Praxis (Bern 1994). 2013 Jan 30;102(3):169-73. doi: 10.1024/1661-8157/a001181. German.

PMID:
23384988
23.

CD161(+)CD4(+) T cells are enriched in the liver during chronic hepatitis and associated with co-secretion of IL-22 and IFN-γ.

Kang YH, Seigel B, Bengsch B, Fleming VM, Billerbeck E, Simmons R, Walker L, Willberg CB, Barnes EJ, Bhagwanani A, Oo YH, Blum HE, Adams DH, Thimme R, Klenerman P.

Front Immunol. 2012 Nov 20;3:346. doi: 10.3389/fimmu.2012.00346. eCollection 2012.

24.

Factors that determine the antiviral efficacy of HCV-specific CD8(+) T cells ex vivo.

Seigel B, Bengsch B, Lohmann V, Bartenschlager R, Blum HE, Thimme R.

Gastroenterology. 2013 Feb;144(2):426-36. doi: 10.1053/j.gastro.2012.10.047. Epub 2012 Nov 7.

PMID:
23142136
25.

Human Th17 cells express high levels of enzymatically active dipeptidylpeptidase IV (CD26).

Bengsch B, Seigel B, Flecken T, Wolanski J, Blum HE, Thimme R.

J Immunol. 2012 Jun 1;188(11):5438-47. doi: 10.4049/jimmunol.1103801. Epub 2012 Apr 25.

26.

Low perforin expression of early differentiated HCV-specific CD8+ T cells limits their hepatotoxic potential.

Jo J, Bengsch B, Seigel B, Rau SJ, Schmidt J, Bisse E, Aichele P, Aichele U, Joeckel L, Royer C, Sá Ferreira K, Borner C, Baumert TF, Blum HE, Lohmann V, Fischer R, Thimme R.

J Hepatol. 2012 Jul;57(1):9-16. doi: 10.1016/j.jhep.2012.02.030. Epub 2012 Mar 14.

PMID:
22425625
27.

Antiviral and regulatory T cell immunity in a patient with stromal interaction molecule 1 deficiency.

Fuchs S, Rensing-Ehl A, Speckmann C, Bengsch B, Schmitt-Graeff A, Bondzio I, Maul-Pavicic A, Bass T, Vraetz T, Strahm B, Ankermann T, Benson M, Caliebe A, Fölster-Holst R, Kaiser P, Thimme R, Schamel WW, Schwarz K, Feske S, Ehl S.

J Immunol. 2012 Feb 1;188(3):1523-33. doi: 10.4049/jimmunol.1102507. Epub 2011 Dec 21.

28.

Regulated expression of nuclear receptor RORγt confers distinct functional fates to NK cell receptor-expressing RORγt(+) innate lymphocytes.

Vonarbourg C, Mortha A, Bui VL, Hernandez PP, Kiss EA, Hoyler T, Flach M, Bengsch B, Thimme R, Hölscher C, Hönig M, Pannicke U, Schwarz K, Ware CF, Finke D, Diefenbach A.

Immunity. 2010 Nov 24;33(5):736-51. doi: 10.1016/j.immuni.2010.10.017.

29.

Coexpression of PD-1, 2B4, CD160 and KLRG1 on exhausted HCV-specific CD8+ T cells is linked to antigen recognition and T cell differentiation.

Bengsch B, Seigel B, Ruhl M, Timm J, Kuntz M, Blum HE, Pircher H, Thimme R.

PLoS Pathog. 2010 Jun 10;6(6):e1000947. doi: 10.1371/journal.ppat.1000947.

30.

Ribavirin ante portas: uptake transporters into hepatocytes dissected.

Bengsch B, Thimme R.

J Hepatol. 2010 Apr;52(4):469-71. doi: 10.1016/j.jhep.2009.12.019. Epub 2010 Jan 7. No abstract available.

31.

Analysis of CD161 expression on human CD8+ T cells defines a distinct functional subset with tissue-homing properties.

Billerbeck E, Kang YH, Walker L, Lockstone H, Grafmueller S, Fleming V, Flint J, Willberg CB, Bengsch B, Seigel B, Ramamurthy N, Zitzmann N, Barnes EJ, Thevanayagam J, Bhagwanani A, Leslie A, Oo YH, Kollnberger S, Bowness P, Drognitz O, Adams DH, Blum HE, Thimme R, Klenerman P.

Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3006-11. doi: 10.1073/pnas.0914839107. Epub 2010 Jan 28.

32.

Hepatitis C virus (HCV) sequence variation induces an HCV-specific T-cell phenotype analogous to spontaneous resolution.

Kasprowicz V, Kang YH, Lucas M, Schulze zur Wiesch J, Kuntzen T, Fleming V, Nolan BE, Longworth S, Berical A, Bengsch B, Thimme R, Lewis-Ximenez L, Allen TM, Kim AY, Klenerman P, Lauer GM.

J Virol. 2010 Feb;84(3):1656-63. doi: 10.1128/JVI.01499-09. Epub 2009 Nov 11. Erratum in: J Virol. 2011 May;85(9):4636.

33.

Role of host genetic factors in the outcome of hepatitis C virus infection.

Bengsch B, Thimme R, Blum HE.

Viruses. 2009 Sep;1(2):104-25. doi: 10.3390/v1020104. Epub 2009 Aug 5.

34.

CD161 expression on hepatitis C virus-specific CD8+ T cells suggests a distinct pathway of T cell differentiation.

Northfield JW, Kasprowicz V, Lucas M, Kersting N, Bengsch B, Kim A, Phillips RE, Walker BD, Thimme R, Lauer G, Klenerman P.

Hepatology. 2008 Feb;47(2):396-406. doi: 10.1002/hep.22040. Erratum in: Hepatology. 2008 Mar;47(3):1102. Bengsh, Bertram [corrected to Bengsch, Bertram].

PMID:
18219672
35.

Memory CD8+ T cell differentiation in viral infection: a cell for all seasons.

Radziewicz H, Uebelhoer L, Bengsch B, Grakoui A.

World J Gastroenterol. 2007 Sep 28;13(36):4848-57. Review.

36.

Analysis of CD127 and KLRG1 expression on hepatitis C virus-specific CD8+ T cells reveals the existence of different memory T-cell subsets in the peripheral blood and liver.

Bengsch B, Spangenberg HC, Kersting N, Neumann-Haefelin C, Panther E, von Weizsäcker F, Blum HE, Pircher H, Thimme R.

J Virol. 2007 Jan;81(2):945-53. Epub 2006 Nov 1.

37.

[CD8(+) T cell differentiation in viral infections].

Bengsch B, Thimme R.

Dtsch Med Wochenschr. 2006 Oct 20;131(42):2355-8. Review. German. No abstract available.

PMID:
17043986

Supplemental Content

Loading ...
Support Center