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Items: 1 to 50 of 60

1.

Deletion of delta-like 1 homologue accelerates fibroblast-myofibroblast differentiation and induces myocardial fibrosis.

Rodriguez P, Sassi Y, Troncone L, Benard L, Ishikawa K, Gordon RE, Lamas S, Laborda J, Hajjar RJ, Lebeche D.

Eur Heart J. 2018 Apr 13. doi: 10.1093/eurheartj/ehy188. [Epub ahead of print]

PMID:
29668883
2.

Dual inhibition of MDMX and MDM2 as a therapeutic strategy in leukemia.

Carvajal LA, Neriah DB, Senecal A, Benard L, Thiruthuvanathan V, Yatsenko T, Narayanagari SR, Wheat JC, Todorova TI, Mitchell K, Kenworthy C, Guerlavais V, Annis DA, Bartholdy B, Will B, Anampa JD, Mantzaris I, Aivado M, Singer RH, Coleman RA, Verma A, Steidl U.

Sci Transl Med. 2018 Apr 11;10(436). pii: eaao3003. doi: 10.1126/scitranslmed.aao3003.

PMID:
29643228
3.

A calsequestrin cis-regulatory motif coupled to a cardiac troponin T promoter improves cardiac AAV9 transduction specificity.

Chamberlain K, Riyad JM, Garnett T, Kohlbrenner E, Mookerjee A, Elmastour F, Benard L, Chen J, VandenDriessche T, Chuah MKL, Marian AJ, Hajjar R, Gurha P, Weber T.

Hum Gene Ther. 2018 Mar 15. doi: 10.1089/hum.2017.188. [Epub ahead of print]

PMID:
29641321
4.

1,2,4-Triazole-3-thione Compounds as Inhibitors of Dizinc Metallo-β-lactamases.

Sevaille L, Gavara L, Bebrone C, De Luca F, Nauton L, Achard M, Mercuri P, Tanfoni S, Borgianni L, Guyon C, Lonjon P, Turan-Zitouni G, Dzieciolowski J, Becker K, Bénard L, Condon C, Maillard L, Martinez J, Frère JM, Dideberg O, Galleni M, Docquier JD, Hernandez JF.

ChemMedChem. 2017 Jun 21;12(12):972-985. doi: 10.1002/cmdc.201700186. Epub 2017 Jun 12.

PMID:
28505394
5.

The Design, Implementation, and Evaluation of a Physiotherapist-Led Clinic for Orthopedic Surveillance for Children with Cerebral Palsy.

Hurtubise K, Shanks R, Benard L.

Phys Occup Ther Pediatr. 2017 Nov;37(4):399-413. doi: 10.1080/01942638.2017.1280869. Epub 2017 Mar 7.

PMID:
28266885
6.

Corrigendum: Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability.

Evrard SM, Lecce L, Michelis KC, Nomura-Kitabayashi A, Pandey G, Purushothaman KR, d'Escamard V, Li JR, Hadri L, Fujitani K, Moreno PR, Benard L, Rimmele P, Cohain A, Mecham B, Randolph GJ, Nabel EG, Hajjar R, Fuster V, Boehm M, Kovacic JC.

Nat Commun. 2017 Feb 16;8:14710. doi: 10.1038/ncomms14710. No abstract available.

7.

The Probability of Inconstancy in Assessment of Cardiac Function Post-Myocardial Infarction in Mice.

Chen J, Hammoudi N, Benard L, Ceholski DK, Zhang S, Lebeche D, Hajjar RJ.

Cardiovasc Pharm Open Access. 2016;5(5). pii: 195. Epub 2016 Sep 9.

8.

Perinatal DDT Exposure Induces Hypertension and Cardiac Hypertrophy in Adult Mice.

La Merrill MA, Sethi S, Benard L, Moshier E, Haraldsson B, Buettner C.

Environ Health Perspect. 2016 Nov;124(11):1722-1727. Epub 2016 Jun 21.

9.

Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability.

Evrard SM, Lecce L, Michelis KC, Nomura-Kitabayashi A, Pandey G, Purushothaman KR, d'Escamard V, Li JR, Hadri L, Fujitani K, Moreno PR, Benard L, Rimmele P, Cohain A, Mecham B, Randolph GJ, Nabel EG, Hajjar R, Fuster V, Boehm M, Kovacic JC.

Nat Commun. 2016 Jun 24;7:11853. doi: 10.1038/ncomms11853.

10.

Cardiac Stim1 Silencing Impairs Adaptive Hypertrophy and Promotes Heart Failure Through Inactivation of mTORC2/Akt Signaling.

Bénard L, Oh JG, Cacheux M, Lee A, Nonnenmacher M, Matasic DS, Kohlbrenner E, Kho C, Pavoine C, Hajjar RJ, Hulot JS.

Circulation. 2016 Apr 12;133(15):1458-71; discussion 1471. doi: 10.1161/CIRCULATIONAHA.115.020678. Epub 2016 Mar 2.

11.

Cytoplasmic Control of Sense-Antisense mRNA Pairs.

Sinturel F, Navickas A, Wery M, Descrimes M, Morillon A, Torchet C, Benard L.

Cell Rep. 2015 Sep 22;12(11):1853-64. doi: 10.1016/j.celrep.2015.08.016. Epub 2015 Sep 3.

12.

High-dose chloroquine is metabolically cardiotoxic by inducing lysosomes and mitochondria dysfunction in a rat model of pressure overload hypertrophy.

Chaanine AH, Gordon RE, Nonnenmacher M, Kohlbrenner E, Benard L, Hajjar RJ.

Physiol Rep. 2015 Jul;3(7). pii: e12413. doi: 10.14814/phy2.12413.

13.

Role of the DHH1 gene in the regulation of monocarboxylic acids transporters expression in Saccharomyces cerevisiae.

Mota S, Vieira N, Barbosa S, Delaveau T, Torchet C, Le Saux A, Garcia M, Pereira A, Lemoine S, Coulpier F, Darzacq X, Benard L, Casal M, Devaux F, Paiva S.

PLoS One. 2014 Nov 3;9(11):e111589. doi: 10.1371/journal.pone.0111589. eCollection 2014.

14.

Deletion of CXCR4 in cardiomyocytes exacerbates cardiac dysfunction following isoproterenol administration.

Wang ER, Jarrah AA, Benard L, Chen J, Schwarzkopf M, Hadri L, Tarzami ST.

Gene Ther. 2014 May;21(5):496-506. doi: 10.1038/gt.2014.23. Epub 2014 Mar 20.

15.

Abnormal muscle mechanosignaling triggers cardiomyopathy in mice with Marfan syndrome.

Cook JR, Carta L, Bénard L, Chemaly ER, Chiu E, Rao SK, Hampton TG, Yurchenco P; GenTAC Registry Consortium, Costa KD, Hajjar RJ, Ramirez F.

J Clin Invest. 2014 Mar;124(3):1329-39. doi: 10.1172/JCI71059. Epub 2014 Feb 17.

16.

Structural analyses of Avocado sunblotch viroid reveal differences in the folding of plus and minus RNA strands.

Delan-Forino C, Deforges J, Benard L, Sargueil B, Maurel MC, Torchet C.

Viruses. 2014 Jan 29;6(2):489-506. doi: 10.3390/v6020489.

17.

Systems pharmacology of adverse event mitigation by drug combinations.

Zhao S, Nishimura T, Chen Y, Azeloglu EU, Gottesman O, Giannarelli C, Zafar MU, Benard L, Badimon JJ, Hajjar RJ, Goldfarb J, Iyengar R.

Sci Transl Med. 2013 Oct 9;5(206):206ra140. doi: 10.1126/scitranslmed.3006548.

18.

Differential patterns of replacement and reactive fibrosis in pressure and volume overload are related to the propensity for ischaemia and involve resistin.

Chemaly ER, Kang S, Zhang S, McCollum L, Chen J, Bénard L, Purushothaman KR, Hajjar RJ, Lebeche D.

J Physiol. 2013 Nov 1;591(21):5337-55. doi: 10.1113/jphysiol.2013.258731. Epub 2013 Sep 9.

19.

Therapeutic efficacy of AAV1.SERCA2a in monocrotaline-induced pulmonary arterial hypertension.

Hadri L, Kratlian RG, Benard L, Maron BA, Dorfmüller P, Ladage D, Guignabert C, Ishikawa K, Aguero J, Ibanez B, Turnbull IC, Kohlbrenner E, Liang L, Zsebo K, Humbert M, Hulot JS, Kawase Y, Hajjar RJ, Leopold JA.

Circulation. 2013 Jul 30;128(5):512-23. doi: 10.1161/CIRCULATIONAHA.113.001585. Epub 2013 Jun 26.

20.

Potential role of BNIP3 in cardiac remodeling, myocardial stiffness, and endoplasmic reticulum: mitochondrial calcium homeostasis in diastolic and systolic heart failure.

Chaanine AH, Gordon RE, Kohlbrenner E, Benard L, Jeong D, Hajjar RJ.

Circ Heart Fail. 2013 May;6(3):572-83. doi: 10.1161/CIRCHEARTFAILURE.112.000200. Epub 2013 Mar 18.

21.

STIM1 and Orai in cardiac hypertrophy and vascular proliferative diseases.

Lompre AM, Benard L, Saliba Y, Aubart F, Fauconnier J, Hulot JS.

Front Biosci (Schol Ed). 2013 Jan 1;5:766-73. Review.

PMID:
23277085
22.

Activation of 5'-3' exoribonuclease Xrn1 by cofactor Dcs1 is essential for mitochondrial function in yeast.

Sinturel F, Bréchemier-Baey D, Kiledjian M, Condon C, Bénard L.

Proc Natl Acad Sci U S A. 2012 May 22;109(21):8264-9. doi: 10.1073/pnas.1120090109. Epub 2012 May 8.

23.

Aldosterone inhibits antifibrotic factors in mouse hypertensive heart.

Azibani F, Benard L, Schlossarek S, Merval R, Tournoux F, Fazal L, Polidano E, Launay JM, Carrier L, Chatziantoniou C, Samuel JL, Delcayre C.

Hypertension. 2012 Jun;59(6):1179-87. doi: 10.1161/HYPERTENSIONAHA.111.190512. Epub 2012 Apr 30.

24.

Plasticity of surface structures and β(2)-adrenergic receptor localization in failing ventricular cardiomyocytes during recovery from heart failure.

Lyon AR, Nikolaev VO, Miragoli M, Sikkel MB, Paur H, Benard L, Hulot JS, Kohlbrenner E, Hajjar RJ, Peters NS, Korchev YE, Macleod KT, Harding SE, Gorelik J.

Circ Heart Fail. 2012 May 1;5(3):357-65. doi: 10.1161/CIRCHEARTFAILURE.111.964692. Epub 2012 Mar 28.

25.

Phaeohyphomycosis due to Exophiala xenobiotica as a cause of fungal arthritis in an HIV-infected patient.

Morio F, Berre JY, Garcia-Hermoso D, Najafzadeh MJ, de Hoog S, Benard L, Michau C.

Med Mycol. 2012 Jul;50(5):513-7. doi: 10.3109/13693786.2011.648218. Epub 2012 Jan 4.

PMID:
22217212
26.

Critical role for stromal interaction molecule 1 in cardiac hypertrophy.

Hulot JS, Fauconnier J, Ramanujam D, Chaanine A, Aubart F, Sassi Y, Merkle S, Cazorla O, Ouillé A, Dupuis M, Hadri L, Jeong D, Mühlstedt S, Schmitt J, Braun A, Bénard L, Saliba Y, Laggerbauer B, Nieswandt B, Lacampagne A, Hajjar RJ, Lompré AM, Engelhardt S.

Circulation. 2011 Aug 16;124(7):796-805. doi: 10.1161/CIRCULATIONAHA.111.031229. Epub 2011 Aug 1.

27.

Protection and reversal of hepatic fibrosis by red wine polyphenols in hyperhomocysteinemic mice.

Noll C, Raaf L, Planque C, Benard L, Secardin L, Petit E, Dairou J, Paul JL, Samuel JL, Delcayre C, Rodrigues-Lima F, Janel N.

J Nutr Biochem. 2011 Sep;22(9):856-64. doi: 10.1016/j.jnutbio.2010.07.010. Epub 2010 Dec 24.

PMID:
21185709
28.

Bacillus subtilis ribonucleases J1 and J2 form a complex with altered enzyme behaviour.

Mathy N, Hébert A, Mervelet P, Bénard L, Dorléans A, Li de la Sierra-Gallay I, Noirot P, Putzer H, Condon C.

Mol Microbiol. 2010 Jan;75(2):489-98. doi: 10.1111/j.1365-2958.2009.07004.x. Epub 2009 Dec 16.

29.

Genomic profiling of microRNAs and messenger RNAs reveals hormonal regulation in microRNA expression in human endometrium.

Kuokkanen S, Chen B, Ojalvo L, Benard L, Santoro N, Pollard JW.

Biol Reprod. 2010 Apr;82(4):791-801. doi: 10.1095/biolreprod.109.081059. Epub 2009 Oct 28.

30.

Real-time fluorescence detection of exoribonucleases.

Sinturel F, Pellegrini O, Xiang S, Tong L, Condon C, Bénard L.

RNA. 2009 Nov;15(11):2057-62. doi: 10.1261/rna.1670909. Epub 2009 Sep 18.

31.

Side-alternating vibration training improves muscle performance in a patient with late-onset pompe disease.

Khan A, Ramage B, Robu I, Benard L.

Case Rep Med. 2009;2009:741087. doi: 10.1155/2009/741087. Epub 2009 May 25.

32.

Effects of aldosterone on coronary function.

Benard L, Milliez P, Ambroisine ML, Messaoudi S, Samuel JL, Delcayre C.

Pharmacol Rep. 2009 Jan-Feb;61(1):58-66. Review.

33.

Ribosomes initiating translation of the hbs mRNA protect it from 5'-to-3' exoribonucleolytic degradation by RNase J1.

Daou-Chabo R, Mathy N, Bénard L, Condon C.

Mol Microbiol. 2009 Mar;71(6):1538-50. doi: 10.1111/j.1365-2958.2009.06620.x. Epub 2009 Feb 2.

34.

Assay of Bacillus subtilis ribonucleases in vitro.

Condon C, Pellegrini O, Mathy N, Bénard L, Redko Y, Oussenko IA, Deikus G, Bechhofer DH.

Methods Enzymol. 2008;447:277-308. doi: 10.1016/S0076-6879(08)02215-5.

PMID:
19161849
35.

In vitro assays of 5' to 3'-exoribonuclease activity.

Pellegrini O, Mathy N, Condon C, Bénard L.

Methods Enzymol. 2008;448:167-83. doi: 10.1016/S0076-6879(08)02609-8.

PMID:
19111176
36.

Proteomic analysis of Staphylococcus aureus biofilms grown in vitro on mechanical heart valve leaflets.

Bénard L, Litzler PY, Cosette P, Lemeland JF, Jouenne T, Junter GA.

J Biomed Mater Res A. 2009 Mar 15;88(4):1069-78. doi: 10.1002/jbm.a.31941.

PMID:
18404712
37.

Biofilm formation on pyrolytic carbon heart valves: influence of surface free energy, roughness, and bacterial species.

Litzler PY, Benard L, Barbier-Frebourg N, Vilain S, Jouenne T, Beucher E, Bunel C, Lemeland JF, Bessou JP.

J Thorac Cardiovasc Surg. 2007 Oct;134(4):1025-32.

38.

[Pulmonary mucormycosis: difficulties in diagnosis and treatment].

Pipet A, Mallet JP, Marty C, Sandron D, Benard L, Leberre JY, Thibaut F, Morin O, Bettembourg A.

Rev Mal Respir. 2007 May;24(5):617-21. French.

PMID:
17519813
39.

5'-to-3' exoribonuclease activity in bacteria: role of RNase J1 in rRNA maturation and 5' stability of mRNA.

Mathy N, Bénard L, Pellegrini O, Daou R, Wen T, Condon C.

Cell. 2007 May 18;129(4):681-92.

40.

Sodium-induced GCN4 expression controls the accumulation of the 5' to 3' RNA degradation inhibitor, 3'-phosphoadenosine 5'-phosphate.

Todeschini AL, Condon C, Bénard L.

J Biol Chem. 2006 Feb 10;281(6):3276-82. Epub 2005 Dec 13.

41.

Identification of the cyclamate interaction site within the transmembrane domain of the human sweet taste receptor subunit T1R3.

Jiang P, Cui M, Zhao B, Snyder LA, Benard LM, Osman R, Max M, Margolskee RF.

J Biol Chem. 2005 Oct 7;280(40):34296-305. Epub 2005 Aug 2.

42.

Molecular mechanisms of sweet receptor function.

Jiang P, Cui M, Ji Q, Snyder L, Liu Z, Benard L, Margolskee RF, Osman R, Max M.

Chem Senses. 2005 Jan;30 Suppl 1:i17-8. No abstract available.

PMID:
15738096
43.

Lactisole interacts with the transmembrane domains of human T1R3 to inhibit sweet taste.

Jiang P, Cui M, Zhao B, Liu Z, Snyder LA, Benard LM, Osman R, Margolskee RF, Max M.

J Biol Chem. 2005 Apr 15;280(15):15238-46. Epub 2005 Jan 24.

44.

The cysteine-rich region of T1R3 determines responses to intensely sweet proteins.

Jiang P, Ji Q, Liu Z, Snyder LA, Benard LM, Margolskee RF, Max M.

J Biol Chem. 2004 Oct 22;279(43):45068-75. Epub 2004 Aug 6.

46.

[A small lesion of the hepatic capsule].

Bénard L, Roche B, Fouret P.

Ann Pathol. 2002 Sep;22(4):331-2. French. No abstract available.

PMID:
12410159
47.

Graft-versus-leukemia effect after suicide-gene-mediated control of graft-versus-host disease.

Litvinova E, Maury S, Boyer O, Bruel S, Benard L, Boisserie G, Klatzmann D, Cohen JL.

Blood. 2002 Sep 15;100(6):2020-5.

48.

[A subcutaneous myxoid nodule of the shoulder].

Bénard L, Roche B, Fouret P.

Ann Pathol. 2001 Dec;21(6):535-6. French. No abstract available.

PMID:
11910941
49.
50.

Effect of combined cytostatic cyclosporin A and cytolytic suicide gene therapy on the prevention of experimental graft-versus-host disease.

Maury S, Litvinova E, Boyer O, Benard L, Bruel S, Klatzmann D, Cohen JL.

Gene Ther. 2002 Feb;9(3):201-7.

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