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Items: 1 to 50 of 116


Dual role of starvation signaling in promoting growth and recovery.

Gurvich Y, Leshkowitz D, Barkai N.

PLoS Biol. 2017 Dec 13;15(12):e2002039. doi: 10.1371/journal.pbio.2002039. eCollection 2017 Dec.


Principles of cellular resource allocation revealed by condition-dependent proteome profiling.

Metzl-Raz E, Kafri M, Yaakov G, Soifer I, Gurvich Y, Barkai N.

Elife. 2017 Aug 31;6. pii: e28034. doi: 10.7554/eLife.28034.


Coupling phenotypic persistence to DNA damage increases genetic diversity in severe stress.

Yaakov G, Lerner D, Bentele K, Steinberger J, Barkai N.

Nat Ecol Evol. 2017 Jan 4;1(1):16. doi: 10.1038/s41559-016-0016.


Heterosis as a consequence of regulatory incompatibility.

Herbst RH, Bar-Zvi D, Reikhav S, Soifer I, Breker M, Jona G, Shimoni E, Schuldiner M, Levy AA, Barkai N.

BMC Biol. 2017 May 11;15(1):38. doi: 10.1186/s12915-017-0373-7.


The Genetic Requirements for Pentose Fermentation in Budding Yeast.

Mittelman K, Barkai N.

G3 (Bethesda). 2017 Jun 7;7(6):1743-1752. doi: 10.1534/g3.117.039610.


Buffering Global Variability of Morphogen Gradients.

Shilo BZ, Barkai N.

Dev Cell. 2017 Mar 13;40(5):429-438. doi: 10.1016/j.devcel.2016.12.012. Review.


Lighting Up ERK Activity.

Shilo BZ, Barkai N.

Dev Cell. 2017 Jan 23;40(2):115-116. doi: 10.1016/j.devcel.2016.12.016.


Early commitment and robust differentiation in colonic crypts.

Tóth B, Ben-Moshe S, Gavish A, Barkai N, Itzkovitz S.

Mol Syst Biol. 2017 Jan 3;13(1):902. doi: 10.15252/msb.20167283.


Model-based analysis of DNA replication profiles: predicting replication fork velocity and initiation rate by profiling free-cycling cells.

Gispan A, Carmi M, Barkai N.

Genome Res. 2017 Feb;27(2):310-319. doi: 10.1101/gr.205849.116. Epub 2016 Dec 27.


Rethinking cell growth models.

Kafri M, Metzl-Raz E, Jonas F, Barkai N.

FEMS Yeast Res. 2016 Nov;16(7). pii: fow081. Epub 2016 Sep 19. Review.


Dealing with Gene-Dosage Imbalance during S Phase.

Bar-Ziv R, Voichek Y, Barkai N.

Trends Genet. 2016 Nov;32(11):717-723. doi: 10.1016/j.tig.2016.08.006. Epub 2016 Aug 26. Review.


Rapid evolutionary adaptation to growth on an 'unfamiliar' carbon source.

Tamari Z, Yona AH, Pilpel Y, Barkai N.

BMC Genomics. 2016 Aug 24;17:674. doi: 10.1186/s12864-016-3010-x.


A role for Rtt109 in buffering gene-dosage imbalance during DNA replication.

Voichek Y, Bar-Ziv R, Barkai N.

Nucleus. 2016 Jul 3;7(4):375-81. doi: 10.1080/19491034.2016.1216743. Review.


Chromatin dynamics during DNA replication.

Bar-Ziv R, Voichek Y, Barkai N.

Genome Res. 2016 Sep;26(9):1245-56. doi: 10.1101/gr.201244.115. Epub 2016 May 25.


Expression homeostasis during DNA replication.

Voichek Y, Bar-Ziv R, Barkai N.

Science. 2016 Mar 4;351(6277):1087-90. doi: 10.1126/science.aad1162.


A WntD-Dependent Integral Feedback Loop Attenuates Variability in Drosophila Toll Signaling.

Rahimi N, Averbukh I, Haskel-Ittah M, Degani N, Schejter ED, Barkai N, Shilo BZ.

Dev Cell. 2016 Feb 22;36(4):401-14. doi: 10.1016/j.devcel.2016.01.023.


A two-step patterning process increases the robustness of periodic patterning in the fly eye.

Gavish A, Barkai N.

J Biol Phys. 2016 Jun;42(3):317-38. doi: 10.1007/s10867-016-9409-4. Epub 2016 Feb 16.


Periodic patterning of the Drosophila eye is stabilized by the diffusible activator Scabrous.

Gavish A, Shwartz A, Weizman A, Schejter E, Shilo BZ, Barkai N.

Nat Commun. 2016 Feb 15;7:10461. doi: 10.1038/ncomms10461.


Natural Diversity in Pentose Fermentation Is Explained by Variations in Histone Deacetylases.

Tamari Z, Barkai N.

Cell Rep. 2016 Jan 26;14(3):458-463. doi: 10.1016/j.celrep.2015.12.048. Epub 2016 Jan 7.


The Cost of Protein Production.

Kafri M, Metzl-Raz E, Jona G, Barkai N.

Cell Rep. 2016 Jan 5;14(1):22-31. doi: 10.1016/j.celrep.2015.12.015. Epub 2015 Dec 24.


DNA Crossover Motifs Associated with Epigenetic Modifications Delineate Open Chromatin Regions in Arabidopsis.

Shilo S, Melamed-Bessudo C, Dorone Y, Barkai N, Levy AA.

Plant Cell. 2015 Sep;27(9):2427-36. doi: 10.1105/tpc.15.00391. Epub 2015 Sep 17.


The Evolutionary Potential of Phenotypic Mutations.

Yanagida H, Gispan A, Kadouri N, Rozen S, Sharon M, Barkai N, Tawfik DS.

PLoS Genet. 2015 Aug 5;11(8):e1005445. doi: 10.1371/journal.pgen.1005445. eCollection 2015 Aug.


Loss of growth homeostasis by genetic decoupling of cell division from biomass growth: implication for size control mechanisms.

Schmidt-Glenewinkel H, Barkai N.

Mol Syst Biol. 2014 Dec 23;10:769. doi: 10.15252/msb.20145513.


Sequential feedback induction stabilizes the phosphate starvation response in budding yeast.

Vardi N, Levy S, Gurvich Y, Polacheck T, Carmi M, Jaitin D, Amit I, Barkai N.

Cell Rep. 2014 Nov 6;9(3):1122-34. doi: 10.1016/j.celrep.2014.10.002. Epub 2014 Oct 30.


Systematic identification of cell size regulators in budding yeast.

Soifer I, Barkai N.

Mol Syst Biol. 2014 Nov 19;10:761. doi: 10.15252/msb.20145345.


Checkpoint-independent scaling of the Saccharomyces cerevisiae DNA replication program.

Gispan A, Carmi M, Barkai N.

BMC Biol. 2014 Oct 7;12:79. doi: 10.1186/s12915-014-0079-z.


Divergence and selectivity of expression-coupled histone modifications in budding yeasts.

Mosesson Y, Voichek Y, Barkai N.

PLoS One. 2014 Jul 9;9(7):e101538. doi: 10.1371/journal.pone.0101538. eCollection 2014.


Scaling morphogen gradients during tissue growth by a cell division rule.

Averbukh I, Ben-Zvi D, Mishra S, Barkai N.

Development. 2014 May;141(10):2150-6. doi: 10.1242/dev.107011.


Coordination of gene expression and growth-rate in natural populations of budding yeast.

Tamari Z, Rosin D, Voichek Y, Barkai N.

PLoS One. 2014 Feb 12;9(2):e88801. doi: 10.1371/journal.pone.0088801. eCollection 2014.


Scaling of dorsal-ventral patterning in the Xenopus laevis embryo.

Ben-Zvi D, Fainsod A, Shilo BZ, Barkai N.

Bioessays. 2014 Feb;36(2):151-6. doi: 10.1002/bies.201300136. Epub 2013 Dec 9.


Budding yeast escape commitment to the phosphate starvation program using gene expression noise.

Vardi N, Levy S, Assaf M, Carmi M, Barkai N.

Curr Biol. 2013 Oct 21;23(20):2051-7. doi: 10.1016/j.cub.2013.08.043. Epub 2013 Oct 3.


Increasing population growth by asymmetric segregation of a limiting resource during cell division.

Avraham N, Soifer I, Carmi M, Barkai N.

Mol Syst Biol. 2013 Apr 16;9:656. doi: 10.1038/msb.2013.13.


Disentangling signaling gradients generated by equivalent sources.

Rappaport N, Barkai N.

J Biol Phys. 2012 Mar;38(2):267-78. doi: 10.1007/s10867-011-9240-x. Epub 2011 Sep 14.


Improved readout precision of the Bicoid morphogen gradient by early decoding.

Tamari Z, Barkai N.

J Biol Phys. 2012 Mar;38(2):317-29. doi: 10.1007/s10867-011-9250-8. Epub 2011 Dec 3.


Creating gradients by morphogen shuttling.

Shilo BZ, Haskel-Ittah M, Ben-Zvi D, Schejter ED, Barkai N.

Trends Genet. 2013 Jun;29(6):339-47. doi: 10.1016/j.tig.2013.01.001. Epub 2013 Jan 29. Review.


Developmental biology: Segmentation within scale.

Barkai N, Shilo BZ.

Nature. 2013 Jan 3;493(7430):32-4. doi: 10.1038/nature11849. Epub 2012 Dec 19. No abstract available.


Linking the signaling cascades and dynamic regulatory networks controlling stress responses.

Gitter A, Carmi M, Barkai N, Bar-Joseph Z.

Genome Res. 2013 Feb;23(2):365-76. doi: 10.1101/gr.138628.112. Epub 2012 Oct 11.


Self-organized shuttling: generating sharp dorsoventral polarity in the early Drosophila embryo.

Haskel-Ittah M, Ben-Zvi D, Branski-Arieli M, Schejter ED, Shilo BZ, Barkai N.

Cell. 2012 Aug 31;150(5):1016-28. doi: 10.1016/j.cell.2012.06.044.


Noise-mean relationship in mutated promoters.

Hornung G, Bar-Ziv R, Rosin D, Tokuriki N, Tawfik DS, Oren M, Barkai N.

Genome Res. 2012 Dec;22(12):2409-17. doi: 10.1101/gr.139378.112. Epub 2012 Jul 20.


Expression noise and acetylation profiles distinguish HDAC functions.

Weinberger L, Voichek Y, Tirosh I, Hornung G, Amit I, Barkai N.

Mol Cell. 2012 Jul 27;47(2):193-202. doi: 10.1016/j.molcel.2012.05.008. Epub 2012 Jun 7.


Efficiency and specificity in microRNA biogenesis.

Barad O, Mann M, Chapnik E, Shenoy A, Blelloch R, Barkai N, Hornstein E.

Nat Struct Mol Biol. 2012 May 13;19(6):650-2. doi: 10.1038/nsmb.2293.


Nucleosome organization affects the sensitivity of gene expression to promoter mutations.

Hornung G, Oren M, Barkai N.

Mol Cell. 2012 May 11;46(3):362-8. doi: 10.1016/j.molcel.2012.02.019. Epub 2012 Mar 29.


Promoter nucleosome organization shapes the evolution of gene expression.

Rosin D, Hornung G, Tirosh I, Gispan A, Barkai N.

PLoS Genet. 2012;8(3):e1002579. doi: 10.1371/journal.pgen.1002579. Epub 2012 Mar 15.


Physical aspects of precision in genetic regulation.

Tamari Z, Barkai N, Fouxon I.

J Biol Phys. 2011 Mar;37(2):213-25. doi: 10.1007/s10867-010-9208-2. Epub 2010 Nov 19.


The competitive advantage of a dual-transporter system.

Levy S, Kafri M, Carmi M, Barkai N.

Science. 2011 Dec 9;334(6061):1408-12. doi: 10.1126/science.1207154.


The era of systems developmental biology.

Perrimon N, Barkai N.

Curr Opin Genet Dev. 2011 Dec;21(6):681-3. doi: 10.1016/j.gde.2011.10.004. Epub 2011 Nov 11. No abstract available.


Robust selection of sensory organ precursors by the Notch-Delta pathway.

Barad O, Hornstein E, Barkai N.

Curr Opin Cell Biol. 2011 Dec;23(6):663-7. doi: 10.1016/ Epub 2011 Sep 29. Review.


Extensive divergence of yeast stress responses through transitions between induced and constitutive activation.

Tirosh I, Wong KH, Barkai N, Struhl K.

Proc Natl Acad Sci U S A. 2011 Oct 4;108(40):16693-8. doi: 10.1073/pnas.1113718108. Epub 2011 Sep 19.


Inferring regulatory mechanisms from patterns of evolutionary divergence.

Tirosh I, Barkai N.

Mol Syst Biol. 2011 Sep 13;7:530. doi: 10.1038/msb.2011.60.


Evolution of nucleosome occupancy: conservation of global properties and divergence of gene-specific patterns.

Tsui K, Dubuis S, Gebbia M, Morse RH, Barkai N, Tirosh I, Nislow C.

Mol Cell Biol. 2011 Nov;31(21):4348-55. doi: 10.1128/MCB.05276-11. Epub 2011 Sep 6.

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