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Structure and Function of the 26S Proteasome.

Bard JAM, Goodall EA, Greene ER, Jonsson E, Dong KC, Martin A.

Annu Rev Biochem. 2018 Apr 13. doi: 10.1146/annurev-biochem-062917-011931. [Epub ahead of print]


Kinetics of plasma Apolipoprotein E isoforms by LC-MS/MS: a pilot study.

Blanchard V, Ramin-Mangata S, Billon-Crossouard S, Aguesse A, Durand M, Chemello K, Nativel B, Flet L, Chetiveaux M, Jacobi D, Bard JM, Ouguerram K, Lambert G, Krempf M, Croyal M.

J Lipid Res. 2018 Mar 14. pii: jlr.P083576. doi: 10.1194/jlr.P083576. [Epub ahead of print]


Tinkering and the Origins of Heritable Anatomical Variation in Vertebrates.

Bard JBL.

Biology (Basel). 2018 Feb 26;7(1). pii: E20. doi: 10.3390/biology7010020. Review.


Lithocholic bile acid inhibits lipogenesis and induces apoptosis in breast cancer cells.

Luu TH, Bard JM, Carbonnelle D, Chaillou C, Huvelin JM, Bobin-Dubigeon C, Nazih H.

Cell Oncol (Dordr). 2018 Feb;41(1):13-24. doi: 10.1007/s13402-017-0353-5. Epub 2017 Oct 9.


Liver X Receptor (LXR)-regulated Genes of Cholesterol Trafficking and Breast Cancer Severity.

Bobin-Dubigeon C, Chauvin A, Brillaud-Meflah V, Boiffard F, Joalland MP, Bard JM.

Anticancer Res. 2017 Oct;37(10):5495-5498.


Daunorubicin 90 mg/m2 in Acute Myeloid Leukemia Induction: Increased Toxicity in Young Patients.

Portugal R, Lyrio R, Loureiro M, Urago K, Bard J, Borchardt A, Garnica M, Nucci M.

Clin Lymphoma Myeloma Leuk. 2017 Aug;17(8):527-531. doi: 10.1016/j.clml.2017.06.018. Epub 2017 Jun 21.


C.H. Waddington's differences with the creators of the modern evolutionary synthesis: a tale of two genes.

Bard JBL.

Hist Philos Life Sci. 2017 Aug 8;39(3):18. doi: 10.1007/s40656-017-0143-4.


LXR Activation Down-regulates Lipid Raft Markers FLOT2 and DHHC5 in MCF-7 Breast Cancer Cells.

Carbonnelle D, Luu TH, Chaillou C, Huvelin JM, Bard JM, Nazih H.

Anticancer Res. 2017 Aug;37(8):4067-4073.


Trypanosome RNA Editing Mediator Complex proteins have distinct functions in gRNA utilization.

Simpson RM, Bruno AE, Chen R, Lott K, Tylec BL, Bard JE, Sun Y, Buck MJ, Read LK.

Nucleic Acids Res. 2017 Jul 27;45(13):7965-7983. doi: 10.1093/nar/gkx458.


Interindividual variability in the cholesterol-lowering effect of supplementation with plant sterols or stanols.

Fumeron F, Bard JM, Lecerf JM.

Nutr Rev. 2017 Feb 1;75(2):134-145. doi: 10.1093/nutrit/nuw059. Review.


Intestinal Proportion of Blautia sp. is Associated with Clinical Stage and Histoprognostic Grade in Patients with Early-Stage Breast Cancer.

Luu TH, Michel C, Bard JM, Dravet F, Nazih H, Bobin-Dubigeon C.

Nutr Cancer. 2017 Feb-Mar;69(2):267-275. doi: 10.1080/01635581.2017.1263750. Epub 2017 Jan 17.


Leptin and adiponectin as new markers of undernutrition in cancer.

Bobin-Dubigeon C, Lefrançois A, Vansteene D, Dupé M, Joalland MP, Bard JM.

Clin Biochem. 2017 Jun;50(9):525-528. doi: 10.1016/j.clinbiochem.2017.01.001. Epub 2017 Jan 6.


Longitudinal Small-Animal PET Imaging of the zQ175 Mouse Model of Huntington Disease Shows In Vivo Changes of Molecular Targets in the Striatum and Cerebral Cortex.

Häggkvist J, Tóth M, Tari L, Varnäs K, Svedberg M, Forsberg A, Nag S, Dominguez C, Munoz-Sanjuan I, Bard J, Wityak J, Varrone A, Halldin C, Mrzljak L.

J Nucl Med. 2017 Apr;58(4):617-622. doi: 10.2967/jnumed.116.180497. Epub 2016 Nov 10.


Something Doesn't Smell Right: When a Patient With Empyema Isn't Responding to Guideline-Based Management.

Chen NY, Bender JM, Bard JD, Trost MJ, Corden MH.

Hosp Pediatr. 2016 Nov;6(11):702-706. Epub 2016 Oct 14. No abstract available.


Analysis of Heteroplasmic Variants in the Cardiac Mitochondrial Genome of Individuals with Down Syndrome.

Hefti E, Bard J, Blanco JG.

Hum Mutat. 2017 Jan;38(1):48-54. doi: 10.1002/humu.23071. Epub 2016 Sep 26.


Impact of a Rapid Blood Culture Assay for Gram-Positive Identification and Detection of Resistance Markers in a Pediatric Hospital.

Felsenstein S, Bender JM, Sposto R, Gentry M, Takemoto C, Bard JD.

Arch Pathol Lab Med. 2016 Mar;140(3):267-75. doi: 10.5858/arpa.2015-0119-OA.


High-throughput sequencing of partially edited trypanosome mRNAs reveals barriers to editing progression and evidence for alternative editing.

Simpson RM, Bruno AE, Bard JE, Buck MJ, Read LK.

RNA. 2016 May;22(5):677-95. doi: 10.1261/rna.055160.115. Epub 2016 Feb 23.


ΔNp63 regulates IL-33 and IL-31 signaling in atopic dermatitis.

Rizzo JM, Oyelakin A, Min S, Smalley K, Bard J, Luo W, Nyquist J, Guttman-Yassky E, Yoshida T, De Benedetto A, Beck LA, Sinha S, Romano RA.

Cell Death Differ. 2016 Jun;23(6):1073-85. doi: 10.1038/cdd.2015.162. Epub 2016 Jan 15.


A Combination of Structural and Empirical Analyses Delineates the Key Contacts Mediating Stability and Affinity Increases in an Optimized Biotherapeutic Single-chain Fv (scFv).

Tu C, Terraube V, Tam AS, Stochaj W, Fennell BJ, Lin L, Stahl M, LaVallie ER, Somers W, Finlay WJ, Mosyak L, Bard J, Cunningham O.

J Biol Chem. 2016 Jan 15;291(3):1267-76. doi: 10.1074/jbc.M115.688010. Epub 2015 Oct 29.


Performance of the CLSI Carba NP and the Rosco Carb Screen Assays Using North American Carbapenemase-Producing Enterobacteriaceae and Pseudomonas aeruginosa Isolates.

Gallagher LC, Roundtree SS, Lancaster DP, Rudin SD, Bard JD, Roberts AL, Marshall SH, Bonomo RA, Sullivan KV.

J Clin Microbiol. 2015 Oct;53(10):3370-3. doi: 10.1128/JCM.01547-15. Epub 2015 Aug 12.


Introducing Law Students to Public Health Law through a Bed Bug Scenario.

Bard JS.

J Law Med Ethics. 2015 Summer;43 Suppl 2:7-11. doi: 10.1111/jlme.12261.


Paired measurement of serum amyloid A (SAA) and paraoxonase 1 (PON1) as useful markers in breast cancer recurrence.

Bobin-Dubigeon C, Lefrançois A, Classe JM, Joalland MP, Bard JM.

Clin Biochem. 2015 Nov;48(16-17):1181-3. doi: 10.1016/j.clinbiochem.2015.07.020. Epub 2015 Jul 17.


Variation analysis of transcriptome changes reveals cochlear genes and their associated functions in cochlear susceptibility to acoustic overstimulation.

Yang S, Cai Q, Bard J, Jamison J, Wang J, Yang W, Hu BH.

Hear Res. 2015 Dec;330(Pt A):78-89. doi: 10.1016/j.heares.2015.04.010. Epub 2015 May 27.


MicroRNA analysis suggests an additional level of feedback regulation in the NF-κB signaling cascade.

Mechtler P, Singhal R, Kichina JV, Bard JE, Buck MJ, Kandel ES.

Oncotarget. 2015 Jul 10;6(19):17097-106.


Global Developmental Gene Programing Involves a Nuclear Form of Fibroblast Growth Factor Receptor-1 (FGFR1).

Terranova C, Narla ST, Lee YW, Bard J, Parikh A, Stachowiak EK, Tzanakakis ES, Buck MJ, Birkaya B, Stachowiak MK.

PLoS One. 2015 Apr 29;10(4):e0123380. doi: 10.1371/journal.pone.0123380. eCollection 2015.


An automated method for efficient, accurate and reproducible construction of RNA-seq libraries.

Tsompana M, Valiyaparambil S, Bard J, Marzullo B, Nowak N, Buck MJ.

BMC Res Notes. 2015 Apr 3;8:124. doi: 10.1186/s13104-015-1089-9.


Lead optimization toward proof-of-concept tools for Huntington's disease within a 4-(1H-pyrazol-4-yl)pyrimidine class of pan-JNK inhibitors.

Wityak J, McGee KF, Conlon MP, Song RH, Duffy BC, Clayton B, Lynch M, Wang G, Freeman E, Haber J, Kitchen DB, Manning DD, Ismail J, Khmelnitsky Y, Michels P, Webster J, Irigoyen M, Luche M, Hultman M, Bai M, Kuok ID, Newell R, Lamers M, Leonard P, Yates D, Matthews K, Ongeri L, Clifton S, Mead T, Deupree S, Wheelan P, Lyons K, Wilson C, Kiselyov A, Toledo-Sherman L, Beconi M, Muñoz-Sanjuan I, Bard J, Dominguez C.

J Med Chem. 2015 Apr 9;58(7):2967-87. doi: 10.1021/jm5013598. Epub 2015 Mar 19.


Sunitinib dose escalation overcomes transient resistance in clear cell renal cell carcinoma and is associated with epigenetic modifications.

Adelaiye R, Ciamporcero E, Miles KM, Sotomayor P, Bard J, Tsompana M, Conroy D, Shen L, Ramakrishnan S, Ku SY, Orillion A, Prey J, Fetterly G, Buck M, Chintala S, Bjarnason GA, Pili R.

Mol Cancer Ther. 2015 Feb;14(2):513-22. doi: 10.1158/1535-7163.MCT-14-0208. Epub 2014 Dec 17.


Effect of phytosterols/stanols on LDL concentration and other surrogate markers of cardiovascular risk.

Bard JM, Paillard F, Lecerf JM.

Diabetes Metab. 2015 Feb;41(1):69-75. doi: 10.1016/j.diabet.2014.11.006. Epub 2014 Dec 9. Review.


Molecular profile of cochlear immunity in the resident cells of the organ of Corti.

Cai Q, Vethanayagam RR, Yang S, Bard J, Jamison J, Cartwright D, Dong Y, Hu BH.

J Neuroinflammation. 2014 Oct 14;11:173. doi: 10.1186/s12974-014-0173-8.


RNA-seq studies reveal new insights into p63 and the transcriptomic landscape of the mouse skin.

Rizzo JM, Romano RA, Bard J, Sinha S.

J Invest Dermatol. 2015 Feb;135(2):629-632. doi: 10.1038/jid.2014.384. Epub 2014 Sep 9. No abstract available.


Improving patient flow at a family health clinic.

Bard JF, Shu Z, Morrice DJ, Wang DE, Poursani R, Leykum L.

Health Care Manag Sci. 2016 Jun;19(2):170-91. doi: 10.1007/s10729-014-9294-y. Epub 2014 Aug 26.


Direct identification of bacteria from positive BacT/ALERT blood culture bottles using matrix-assisted laser desorption ionization-time-of-flight mass spectrometry.

Mestas J, Felsenstein S, Bard JD.

Diagn Microbiol Infect Dis. 2014 Nov;80(3):193-6. doi: 10.1016/j.diagmicrobio.2014.07.008. Epub 2014 Jul 31.


Pediatric carbapenem-resistant Enterobacteriaceae in Los Angeles, California, a high-prevalence region in the United States.

Pannaraj PS, Bard JD, Cerini C, Weissman SJ.

Pediatr Infect Dis J. 2015 Jan;34(1):11-6. doi: 10.1097/INF.0000000000000471.


Structural changes in the gut microbiome of constipated patients.

Zhu L, Liu W, Alkhouri R, Baker RD, Bard JE, Quigley EM, Baker SS.

Physiol Genomics. 2014 Sep 15;46(18):679-86. doi: 10.1152/physiolgenomics.00082.2014. Epub 2014 Jul 29.


Generating anatomical variation through mutations in networks - implications for evolution.

Bard J.

J Anat. 2014 Aug;225(2):123-31. doi: 10.1111/joa.12205. Epub 2014 Jun 17.


A monoclonal antibody TrkB receptor agonist as a potential therapeutic for Huntington's disease.

Todd D, Gowers I, Dowler SJ, Wall MD, McAllister G, Fischer DF, Dijkstra S, Fratantoni SA, van de Bospoort R, Veenman-Koepke J, Flynn G, Arjomand J, Dominguez C, Munoz-Sanjuan I, Wityak J, Bard JA.

PLoS One. 2014 Feb 4;9(2):e87923. doi: 10.1371/journal.pone.0087923. eCollection 2014.


Would research ethics survive the defunding of the research university?

Bard JS.

Hastings Cent Rep. 2014 Jan-Feb;44(1):11-2. doi: 10.1002/hast.248. No abstract available.


Advances in huntington disease drug discovery: novel approaches to model disease phenotypes.

Bard J, Wall MD, Lazari O, Arjomand J, Munoz-Sanjuan I.

J Biomol Screen. 2014 Feb;19(2):191-204. doi: 10.1177/1087057113510320. Epub 2013 Nov 6. Review.


Macrophage apolipoprotein E and proliferation of MCF-7 breast cancer cells: role of LXR.

El Roz A, Bard JM, Valin S, Huvelin JM, Nazih H.

Anticancer Res. 2013 Sep;33(9):3783-9.


Case Study. Futility on the border. Commentary.

Bard JS.

Hastings Cent Rep. 2013 Jul-Aug;43(4):12. No abstract available.


Short communication: Paraoxonase 1 (PON1) in French HIV-infected patients under antiretroviral therapy: relationship with the metabolic syndrome and inflammation.

Bobin-Dubigeon C, Biron C, Volteau C, Piroth L, Biron A, Perré P, Leport C, Prazuck T, Sébille-Rivain V, Raffi F, Bard JM.

AIDS Res Hum Retroviruses. 2013 Dec;29(12):1571-4. doi: 10.1089/AID.2013.0010. Epub 2013 Aug 2.


A new, validated wipe-sampling procedure coupled to LC-MS analysis for the simultaneous determination of 5-fluorouracil, doxorubicin and cyclophosphamide in surface contamination.

Bobin-Dubigeon C, Amiand M, Percheron C, Audeval C, Rochard S, Leynia P, Bard JM.

J Anal Toxicol. 2013 Sep;37(7):433-9. doi: 10.1093/jat/bkt045. Epub 2013 Jul 4.


A combined natural supplement lowers LDL cholesterol in subjects with moderate untreated hypercholesterolemia: a randomized placebo-controlled trial.

Barrat E, Zaïr Y, Ogier N, Housez B, Vergara C, Maudet C, Lescuyer JF, Bard JM, Carpentier YA, Cazaubiel M, Peltier SL.

Int J Food Sci Nutr. 2013 Nov;64(7):882-9. doi: 10.3109/09637486.2013.809405. Epub 2013 Jul 2.


FOXO1 regulates expression of a microRNA cluster on X chromosome.

Singhal R, Bard JE, Nowak NJ, Buck MJ, Kandel ES.

Aging (Albany NY). 2013 May;5(5):347-56.


Transcriptome characterization by RNA-Seq reveals the involvement of the complement components in noise-traumatized rat cochleae.

Patel M, Hu Z, Bard J, Jamison J, Cai Q, Hu BH.

Neuroscience. 2013 Sep 17;248:1-16. doi: 10.1016/j.neuroscience.2013.05.038. Epub 2013 May 30.


The anti-proliferative and pro-apoptotic effects of the trans9, trans11 conjugated linoleic acid isomer on MCF-7 breast cancer cells are associated with LXR activation.

El Roz A, Bard JM, Huvelin JM, Nazih H.

Prostaglandins Leukot Essent Fatty Acids. 2013 Apr;88(4):265-72. doi: 10.1016/j.plefa.2012.12.006. Epub 2013 Feb 1.


Discovery of HSD-621 as a Potential Agent for the Treatment of Type 2 Diabetes.

Wan ZK, Chenail E, Li HQ, Ipek M, Xiang J, Suri V, Hahm S, Bard J, Svenson K, Xu X, Tian X, Wang M, Li X, Johnson CE, Qadri A, Panza D, Perreault M, Mansour TS, Tobin JF, Saiah E.

ACS Med Chem Lett. 2012 Nov 23;4(1):118-23. doi: 10.1021/ml300352x. eCollection 2013 Jan 10.

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