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Items: 15


CRISPR whole-genome screening identifies new necroptosis regulators and RIPK1 alternative splicing.

Callow MG, Watanabe C, Wickliffe KE, Bainer R, Kummerfield S, Weng J, Cuellar T, Janakiraman V, Chen H, Chih B, Liang Y, Haley B, Newton K, Costa MR.

Cell Death Dis. 2018 Feb 15;9(3):261. doi: 10.1038/s41419-018-0301-y.


PRC2-mediated repression of SMARCA2 predicts EZH2 inhibitor activity in SWI/SNF mutant tumors.

Januario T, Ye X, Bainer R, Alicke B, Smith T, Haley B, Modrusan Z, Gould S, Yauch RL.

Proc Natl Acad Sci U S A. 2017 Nov 14;114(46):12249-12254. doi: 10.1073/pnas.1703966114. Epub 2017 Oct 30.


A p53-regulated apoptotic gene signature predicts treatment response and outcome in pediatric acute lymphoblastic leukemia.

Bainer RO, Trendowski MR, Cheng C, Pei D, Yang W, Paugh SW, Goss KH, Skol AD, Pavlidis P, Pui CH, Gilliam TC, Evans WE, Onel K.

Cancer Manag Res. 2017 Sep 13;9:397-410. doi: 10.2147/CMAR.S139864. eCollection 2017.


Comprehensive characterization of DNA methylation changes in Fuchs endothelial corneal dystrophy.

Khuc E, Bainer R, Wolf M, Clay SM, Weisenberger DJ, Kemmer J, Weaver VM, Hwang DG, Chan MF.

PLoS One. 2017 Apr 6;12(4):e0175112. doi: 10.1371/journal.pone.0175112. eCollection 2017.


Gene expression in local stroma reflects breast tumor states and predicts patient outcome.

Bainer R, Frankenberger C, Rabe D, An G, Gilad Y, Rosner MR.

Sci Rep. 2016 Dec 16;6:39240. doi: 10.1038/srep39240.


Metastasis Suppressors Regulate the Tumor Microenvironment by Blocking Recruitment of Prometastatic Tumor-Associated Macrophages.

Frankenberger C, Rabe D, Bainer R, Sankarasharma D, Chada K, Krausz T, Gilad Y, Becker L, Rosner MR.

Cancer Res. 2015 Oct 1;75(19):4063-73. doi: 10.1158/0008-5472.CAN-14-3394. Epub 2015 Aug 3.


Force engages vinculin and promotes tumor progression by enhancing PI3K activation of phosphatidylinositol (3,4,5)-triphosphate.

Rubashkin MG, Cassereau L, Bainer R, DuFort CC, Yui Y, Ou G, Paszek MJ, Davidson MW, Chen YY, Weaver VM.

Cancer Res. 2014 Sep 1;74(17):4597-611. doi: 10.1158/0008-5472.CAN-13-3698.


The cancer glycocalyx mechanically primes integrin-mediated growth and survival.

Paszek MJ, DuFort CC, Rossier O, Bainer R, Mouw JK, Godula K, Hudak JE, Lakins JN, Wijekoon AC, Cassereau L, Rubashkin MG, Magbanua MJ, Thorn KS, Davidson MW, Rugo HS, Park JW, Hammer DA, Giannone G, Bertozzi CR, Weaver VM.

Nature. 2014 Jul 17;511(7509):319-25. doi: 10.1038/nature13535. Epub 2014 Jun 25.


Tissue mechanics modulate microRNA-dependent PTEN expression to regulate malignant progression.

Mouw JK, Yui Y, Damiano L, Bainer RO, Lakins JN, Acerbi I, Ou G, Wijekoon AC, Levental KR, Gilbert PM, Hwang ES, Chen YY, Weaver VM.

Nat Med. 2014 Apr;20(4):360-7. doi: 10.1038/nm.3497. Epub 2014 Mar 16.


Cell biology. Strength under tension.

Bainer R, Weaver V.

Science. 2013 Aug 30;341(6149):965-6. doi: 10.1126/science.1243643. No abstract available.


Using MKK4's metastasis suppressor function to identify and dissect cancer cell-microenvironment interactions during metastatic colonization.

Krishnan V, Stadick N, Clark R, Bainer R, Veneris JT, Khan S, Drew A, Rinker-Schaeffer C.

Cancer Metastasis Rev. 2012 Dec;31(3-4):605-13. doi: 10.1007/s10555-012-9371-y. Review.


Time-dependent transcriptional profiling links gene expression to mitogen-activated protein kinase kinase 4 (MKK4)-mediated suppression of omental metastatic colonization.

Bainer RO, Veneris JT, Yamada SD, Montag A, Lingen MW, Gilad Y, Rinker-Schaeffer CW.

Clin Exp Metastasis. 2012 Jun;29(5):397-408. doi: 10.1007/s10585-011-9448-y. Epub 2012 Feb 21.


Comparative RNA sequencing reveals substantial genetic variation in endangered primates.

Perry GH, Melsted P, Marioni JC, Wang Y, Bainer R, Pickrell JK, Michelini K, Zehr S, Yoder AD, Stephens M, Pritchard JK, Gilad Y.

Genome Res. 2012 Apr;22(4):602-10. doi: 10.1101/gr.130468.111. Epub 2011 Dec 29.


From prostate to bone: key players in prostate cancer bone metastasis.

Thobe MN, Clark RJ, Bainer RO, Prasad SM, Rinker-Schaeffer CW.

Cancers (Basel). 2011;3(1):478-93. doi: 10.3390/cancers3010478.


A high-throughput capillary assay for bacterial chemotaxis.

Bainer R, Park H, Cluzel P.

J Microbiol Methods. 2003 Oct;55(1):315-9.


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