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Items: 7

1.

Mitochondrial tyrosyl-DNA phosphodiesterase 2 and its TDP2S short isoform.

Huang SN, Dalla Rosa I, Michaels SA, Tulumello DV, Agama K, Khiati S, Jean SR, Baechler SA, Factor VM, Varma S, Murai J, Miller Jenkins LM, Kelley SO, Pommier Y.

EMBO Rep. 2018 Feb 9. pii: e42139. doi: 10.15252/embr.201642139. [Epub ahead of print]

PMID:
29438979
2.

SLFN11 Blocks Stressed Replication Forks Independently of ATR.

Murai J, Tang SW, Leo E, Baechler SA, Redon CE, Zhang H, Al Abo M, Rajapakse VN, Nakamura E, Jenkins LMM, Aladjem MI, Pommier Y.

Mol Cell. 2018 Feb 1;69(3):371-384.e6. doi: 10.1016/j.molcel.2018.01.012.

PMID:
29395061
3.

Topoisomerase poisoning by genistein in the intestine of rats.

Baechler SA, Soukup ST, Molzberger AF, Kulling SE, Diel P, Marko D.

Toxicol Lett. 2016 Jan 22;243:88-97. doi: 10.1016/j.toxlet.2015.12.009. Epub 2015 Dec 23.

PMID:
26723871
4.

Lack of mitochondrial topoisomerase I (TOP1mt) impairs liver regeneration.

Khiati S, Baechler SA, Factor VM, Zhang H, Huang SY, Dalla Rosa I, Sourbier C, Neckers L, Thorgeirsson SS, Pommier Y.

Proc Natl Acad Sci U S A. 2015 Sep 8;112(36):11282-7. doi: 10.1073/pnas.1511016112. Epub 2015 Aug 24.

5.

Oxidative metabolism enhances the cytotoxic and genotoxic properties of the soy isoflavone daidzein.

Baechler SA, Schroeter A, Walker J, Aichinger G, Marko D.

Mol Nutr Food Res. 2014 Jun;58(6):1269-81. doi: 10.1002/mnfr.201300531. Epub 2014 Mar 3.

PMID:
24585454
6.

Topoisomerase II-targeting properties of a grapevine-shoot extract and resveratrol oligomers.

Baechler SA, Schroeter A, Dicker M, Steinberg P, Marko D.

J Agric Food Chem. 2014 Jan 22;62(3):780-8. doi: 10.1021/jf4046182. Epub 2014 Jan 10.

PMID:
24369070
7.

Synthesis, topoisomerase-targeting activity and growth inhibition of lycobetaine analogs.

Baechler SA, Fehr M, Habermeyer M, Hofmann A, Merz KH, Fiebig HH, Marko D, Eisenbrand G.

Bioorg Med Chem. 2013 Feb 1;21(3):814-23. doi: 10.1016/j.bmc.2012.11.011. Epub 2012 Nov 26.

PMID:
23266176

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