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Items: 44

1.

A Short Double-Stapled Peptide Inhibits Respiratory Syncytial Virus Entry and Spreading.

Gaillard V, Galloux M, Garcin D, Eléouët JF, Le Goffic R, Larcher T, Rameix-Welti MA, Boukadiri A, Héritier J, Segura JM, Baechler E, Arrell M, Mottet-Osman G, Nyanguile O.

Antimicrob Agents Chemother. 2017 Mar 24;61(4). pii: e02241-16. doi: 10.1128/AAC.02241-16. Print 2017 Apr.

2.

Gene Expression Profiling in Blood and Affected Muscle Tissues Reveals Differential Activation Pathways in Patients with New-onset Juvenile and Adult Dermatomyositis.

López De Padilla CM, Crowson CS, Hein MS, Pendegraft RS, Strausbauch MA, Niewold TB, Ernste FC, Peterson E, Baechler EC, Reed AM.

J Rheumatol. 2017 Jan;44(1):117-124. doi: 10.3899/jrheum.160293. Epub 2016 Nov 1.

3.

Association of environmental markers with childhood type 1 diabetes mellitus revealed by a long questionnaire on early life exposures and lifestyle in a case-control study.

Balazard F, Le Fur S, Valtat S, Valleron AJ, Bougnères P; Isis-Diab collaborative group, Thevenieau D, Chatel CF, Desailloud R, Bony-Trifunovic H, Ducluzeau PH, Coutant R, Caudrelier S, Pambou A, Dubosclard E, Joubert F, Jan P, Marcoux E, Bertrand AM, Mignot B, Penformis A, Stuckens C, Piquemal R, Barat P, Rigalleau V, Stheneur C, Fournier S, Kerlan V, Metz C, Fargeot-Espaliat A, Reznic Y, Olivier F, Gueorguieva I, Monier A, Radet C, Gajdos V, Terral D, Vervel C, Bendifallah D, Signor CB, Dervaux D, Benmahammed A, Loeuille GA, Popelard F, Guillou A, Benhamou PY, Khoury J, Brossier JP, Bassil J, Clavel S, Le Luyer B, Bougnères P, Labay F, Guemas I, Weill J, Cappoen JP, Nadalon S, Lienhardt-Roussie A, Paoli A, Kerouedan C, Yollin E, Nicolino M, Simonin G, Cohen J, Atlan C, Tamboura A, Dubourg H, Pignol ML, Talon P, Jellimann S, Chaillous L, Baron S, Bortoluzzi MN, Baechler E, Salet R, Zelinsky-Gurung A, Dallavale F, Larger E, Laloi-Michelin M, Gautier JF, Guérin B, Oilleau L, Pantalone L, Lukas C, Guilhem I, De Kerdanet M, Wielickzo MC, Priou-Guesdon M, Richard O, Kurtz F, Laisney N, Ancelle D, Parlier G, Boniface C, Bockel DP, Dufillot D, Razafimahefa B, Gourdy P, Lecomte P, Pepin-Donat M, Combes-Moukhovsky ME, Zymmermann B, Raoulx M, Dumont AG.

BMC Public Health. 2016 Sep 29;16(1):1021.

4.

High-Resolution Analysis of Antibodies to Post-Translational Modifications Using Peptide Nanosensor Microarrays.

Lee JR, Haddon DJ, Gupta N, Price JV, Credo GM, Diep VK, Kim K, Hall DA, Baechler EC, Petri M, Varma M, Utz PJ, Wang SX.

ACS Nano. 2016 Dec 27;10(12):10652-10660. doi: 10.1021/acsnano.6b03786. Epub 2016 Sep 20.

5.

Multiplex giant magnetoresistive biosensor microarrays identify interferon-associated autoantibodies in systemic lupus erythematosus.

Lee JR, Haddon DJ, Wand HE, Price JV, Diep VK, Hall DA, Petri M, Baechler EC, Balboni IM, Utz PJ, Wang SX.

Sci Rep. 2016 Jun 9;6:27623. doi: 10.1038/srep27623.

6.

Mapping epitopes of U1-70K autoantibodies at single-amino acid resolution.

Haddon DJ, Jarrell JA, Diep VK, Wand HE, Price JV, Tangsombatvisit S, Credo GM, Mackey S, Dekker CL, Baechler EC, Liu CL, Varma M, Utz PJ.

Autoimmunity. 2015;48(8):513-23. doi: 10.3109/08916934.2015.1077233. Epub 2015 Aug 31.

7.

PTPN22 Variant R620W Is Associated With Reduced Toll-like Receptor 7-Induced Type I Interferon in Systemic Lupus Erythematosus.

Wang Y, Ewart D, Crabtree JN, Yamamoto A, Baechler EC, Fazeli P, Peterson EJ.

Arthritis Rheumatol. 2015 Sep;67(9):2403-14. doi: 10.1002/art.39211.

8.

Adipokine gene expression in peripheral blood of adult and juvenile dermatomyositis patients and their relation to clinical parameters and disease activity measures.

Olazagasti JM, Hein M, Crowson CS, de Padilla CL, Peterson E, Baechler EC, Reed AM.

J Inflamm (Lond). 2015 Apr 9;12:29. doi: 10.1186/s12950-015-0075-2. eCollection 2015.

9.

Using gene expression to improve the power of genome-wide association analysis.

Ho YY, Baechler EC, Ortmann W, Behrens TW, Graham RR, Bhangale TR, Pan W.

Hum Hered. 2014;78(2):94-103. doi: 10.1159/000362837. Epub 2014 Jul 30.

10.

Primary EBV infection induces an expression profile distinct from other viruses but similar to hemophagocytic syndromes.

Dunmire SK, Odumade OA, Porter JL, Reyes-Genere J, Schmeling DO, Bilgic H, Fan D, Baechler EC, Balfour HH Jr, Hogquist KA.

PLoS One. 2014 Jan 17;9(1):e85422. doi: 10.1371/journal.pone.0085422. eCollection 2014.

11.

Neutrophil-mediated IFN activation in the bone marrow alters B cell development in human and murine systemic lupus erythematosus.

Palanichamy A, Bauer JW, Yalavarthi S, Meednu N, Barnard J, Owen T, Cistrone C, Bird A, Rabinovich A, Nevarez S, Knight JS, Dedrick R, Rosenberg A, Wei C, Rangel-Moreno J, Liesveld J, Sanz I, Baechler E, Kaplan MJ, Anolik JH.

J Immunol. 2014 Feb 1;192(3):906-18. doi: 10.4049/jimmunol.1302112. Epub 2013 Dec 30.

12.

Protein microarray analysis reveals BAFF-binding autoantibodies in systemic lupus erythematosus.

Price JV, Haddon DJ, Kemmer D, Delepine G, Mandelbaum G, Jarrell JA, Gupta R, Balboni I, Chakravarty EF, Sokolove J, Shum AK, Anderson MS, Cheng MH, Robinson WH, Browne SK, Holland SM, Baechler EC, Utz PJ.

J Clin Invest. 2013 Dec;123(12):5135-45. doi: 10.1172/JCI70231. Epub 2013 Nov 25.

13.

BAFF expression correlates with idiopathic inflammatory myopathy disease activity measures and autoantibodies.

López De Padilla CM, McNallan KT, Crowson CS, Bilgic H, Bram RJ, Hein MS, Ytterberg SR, Amin S, Peterson EJ, Baechler EC, Reed AM.

J Rheumatol. 2013 Mar;40(3):294-302. doi: 10.3899/jrheum.120555. Epub 2013 Jan 15.

PMID:
23322463
14.

Increased expression of ADAMTS13 mRNA correlates with ischemic cerebrovascular disease in systemic lupus erythematosus patients.

López De Padilla CM, Hein MS, Crowson CS, Choo CS, Green AB, Petri M, Bilgic H, Baechler EC, Reed AM.

SAGE Open Med. 2013 Nov 29;1:2050312113514404. doi: 10.1177/2050312113514404. eCollection 2013.

15.

On silico peptide microarrays for high-resolution mapping of antibody epitopes and diverse protein-protein interactions.

Price JV, Tangsombatvisit S, Xu G, Yu J, Levy D, Baechler EC, Gozani O, Varma M, Utz PJ, Liu CL.

Nat Med. 2012 Sep;18(9):1434-40.

16.

Oxidative stress and fatigue in systemic lupus erythematosus.

Segal BM, Thomas W, Zhu X, Diebes A, McElvain G, Baechler E, Gross M.

Lupus. 2012 Aug;21(9):984-92. doi: 10.1177/0961203312444772. Epub 2012 Apr 16.

PMID:
22508802
17.

Type I interferon pathway in adult and juvenile dermatomyositis.

Baechler EC, Bilgic H, Reed AM.

Arthritis Res Ther. 2011;13(6):249. doi: 10.1186/ar3531. Epub 2011 Dec 22. Review.

18.

Ebf1 or Pax5 haploinsufficiency synergizes with STAT5 activation to initiate acute lymphoblastic leukemia.

Heltemes-Harris LM, Willette MJ, Ramsey LB, Qiu YH, Neeley ES, Zhang N, Thomas DA, Koeuth T, Baechler EC, Kornblau SM, Farrar MA.

J Exp Med. 2011 Jun 6;208(6):1135-49. doi: 10.1084/jem.20101947. Epub 2011 May 23.

19.

Interleukin-6 and type I interferon-regulated genes and chemokines mark disease activity in dermatomyositis.

Bilgic H, Ytterberg SR, Amin S, McNallan KT, Wilson JC, Koeuth T, Ellingson S, Newman B, Bauer JW, Peterson EJ, Baechler EC, Reed AM.

Arthritis Rheum. 2009 Nov;60(11):3436-46. doi: 10.1002/art.24936.

20.

A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus.

Gateva V, Sandling JK, Hom G, Taylor KE, Chung SA, Sun X, Ortmann W, Kosoy R, Ferreira RC, Nordmark G, Gunnarsson I, Svenungsson E, Padyukov L, Sturfelt G, Jönsen A, Bengtsson AA, Rantapää-Dahlqvist S, Baechler EC, Brown EE, Alarcón GS, Edberg JC, Ramsey-Goldman R, McGwin G Jr, Reveille JD, Vilá LM, Kimberly RP, Manzi S, Petri MA, Lee A, Gregersen PK, Seldin MF, Rönnblom L, Criswell LA, Syvänen AC, Behrens TW, Graham RR.

Nat Genet. 2009 Nov;41(11):1228-33. doi: 10.1038/ng.468. Epub 2009 Oct 18.

21.

Interferon-regulated chemokines as biomarkers of systemic lupus erythematosus disease activity: a validation study.

Bauer JW, Petri M, Batliwalla FM, Koeuth T, Wilson J, Slattery C, Panoskaltsis-Mortari A, Gregersen PK, Behrens TW, Baechler EC.

Arthritis Rheum. 2009 Oct;60(10):3098-107. doi: 10.1002/art.24803.

22.

Longitudinal expression of type I interferon responsive genes in systemic lupus erythematosus.

Petri M, Singh S, Tesfasyone H, Dedrick R, Fry K, Lal P, Williams G, Bauer J, Gregersen P, Behrens T, Baechler E.

Lupus. 2009 Oct;18(11):980-9. doi: 10.1177/0961203309105529.

23.

Gene-expression profiling in rheumatic disease: tools and therapeutic potential.

Bauer JW, Bilgic H, Baechler EC.

Nat Rev Rheumatol. 2009 May;5(5):257-65. doi: 10.1038/nrrheum.2009.50. Review.

PMID:
19412192
24.

Peripheral blood gene expression profiling in Sjögren's syndrome.

Emamian ES, Leon JM, Lessard CJ, Grandits M, Baechler EC, Gaffney PM, Segal B, Rhodus NL, Moser KL.

Genes Immun. 2009 Jun;10(4):285-96. doi: 10.1038/gene.2009.20. Epub 2009 Apr 30.

25.

Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.

International Consortium for Systemic Lupus Erythematosus Genetics (SLEGEN), Harley JB, Alarcón-Riquelme ME, Criswell LA, Jacob CO, Kimberly RP, Moser KL, Tsao BP, Vyse TJ, Langefeld CD, Nath SK, Guthridge JM, Cobb BL, Mirel DB, Marion MC, Williams AH, Divers J, Wang W, Frank SG, Namjou B, Gabriel SB, Lee AT, Gregersen PK, Behrens TW, Taylor KE, Fernando M, Zidovetzki R, Gaffney PM, Edberg JC, Rioux JD, Ojwang JO, James JA, Merrill JT, Gilkeson GS, Seldin MF, Yin H, Baechler EC, Li QZ, Wakeland EK, Bruner GR, Kaufman KM, Kelly JA.

Nat Genet. 2008 Feb;40(2):204-10. doi: 10.1038/ng.81. Epub 2008 Jan 20.

26.

Defining a new molecular basis of systemic lupus erythematosus through transcriptional profiling.

Gaffney PM, Moser KL, Baechler EC.

Expert Rev Clin Immunol. 2007 Nov;3(6):913-23. doi: 10.1586/1744666X.3.6.913.

PMID:
20477140
27.

An interferon signature in the peripheral blood of dermatomyositis patients is associated with disease activity.

Baechler EC, Bauer JW, Slattery CA, Ortmann WA, Espe KJ, Novitzke J, Ytterberg SR, Gregersen PK, Behrens TW, Reed AM.

Mol Med. 2007 Jan-Feb;13(1-2):59-68.

28.

Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus.

Graham RR, Kyogoku C, Sigurdsson S, Vlasova IA, Davies LR, Baechler EC, Plenge RM, Koeuth T, Ortmann WA, Hom G, Bauer JW, Gillett C, Burtt N, Cunninghame Graham DS, Onofrio R, Petri M, Gunnarsson I, Svenungsson E, Rönnblom L, Nordmark G, Gregersen PK, Moser K, Gaffney PM, Criswell LA, Vyse TJ, Syvänen AC, Bohjanen PR, Daly MJ, Behrens TW, Altshuler D.

Proc Natl Acad Sci U S A. 2007 Apr 17;104(16):6758-63. Epub 2007 Apr 5.

29.

Elevated serum levels of interferon-regulated chemokines are biomarkers for active human systemic lupus erythematosus.

Bauer JW, Baechler EC, Petri M, Batliwalla FM, Crawford D, Ortmann WA, Espe KJ, Li W, Patel DD, Gregersen PK, Behrens TW.

PLoS Med. 2006 Dec;3(12):e491.

30.

A distinct inflammatory gene expression profile in patients with psoriatic arthritis.

Stoeckman AK, Baechler EC, Ortmann WA, Behrens TW, Michet CJ, Peterson EJ.

Genes Immun. 2006 Oct;7(7):583-91. Epub 2006 Sep 14.

PMID:
16971957
31.

A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus.

Graham RR, Kozyrev SV, Baechler EC, Reddy MV, Plenge RM, Bauer JW, Ortmann WA, Koeuth T, González Escribano MF; Argentine and Spanish Collaborative Groups, Pons-Estel B, Petri M, Daly M, Gregersen PK, Martín J, Altshuler D, Behrens TW, Alarcón-Riquelme ME.

Nat Genet. 2006 May;38(5):550-5. Epub 2006 Apr 16.

PMID:
16642019
32.

Gene expression profiling in human autoimmunity.

Baechler EC, Batliwalla FM, Reed AM, Peterson EJ, Gaffney PM, Moser KL, Gregersen PK, Behrens TW.

Immunol Rev. 2006 Apr;210:120-37. Review.

PMID:
16623768
33.

Microarray analyses of peripheral blood cells identifies unique gene expression signature in psoriatic arthritis.

Batliwalla FM, Li W, Ritchlin CT, Xiao X, Brenner M, Laragione T, Shao T, Durham R, Kemshetti S, Schwarz E, Coe R, Kern M, Baechler EC, Behrens TW, Gregersen PK, Gulko PS.

Mol Med. 2005 Jan-Dec;11(1-12):21-9.

34.

Progress towards understanding the genetic pathogenesis of systemic lupus erythematosus.

Behrens TW, Graham RR, Kyogoku C, Baechler EC, Ramos PS, Gillett C, Bauer J, Ortmann WA, Hippen KL, Peterson E, Langefeld CD, Moser KL, Gaffney PM, Gregersen PK.

Novartis Found Symp. 2005;267:145-60; discussion 160-4.

PMID:
15999805
35.

Peripheral blood gene expression profiling in rheumatoid arthritis.

Batliwalla FM, Baechler EC, Xiao X, Li W, Balasubramanian S, Khalili H, Damle A, Ortmann WA, Perrone A, Kantor AB, Gulko PS, Kern M, Furie R, Behrens TW, Gregersen PK.

Genes Immun. 2005 Aug;6(5):388-97.

PMID:
15973463
36.

The emerging role of interferon in human systemic lupus erythematosus.

Baechler EC, Gregersen PK, Behrens TW.

Curr Opin Immunol. 2004 Dec;16(6):801-7. Review.

PMID:
15511676
37.

Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE.

Kyogoku C, Langefeld CD, Ortmann WA, Lee A, Selby S, Carlton VE, Chang M, Ramos P, Baechler EC, Batliwalla FM, Novitzke J, Williams AH, Gillett C, Rodine P, Graham RR, Ardlie KG, Gaffney PM, Moser KL, Petri M, Begovich AB, Gregersen PK, Behrens TW.

Am J Hum Genet. 2004 Sep;75(3):504-7. Epub 2004 Jul 23.

38.

Expression levels for many genes in human peripheral blood cells are highly sensitive to ex vivo incubation.

Baechler EC, Batliwalla FM, Karypis G, Gaffney PM, Moser K, Ortmann WA, Espe KJ, Balasubramanian S, Hughes KM, Chan JP, Begovich A, Chang SY, Gregersen PK, Behrens TW.

Genes Immun. 2004 Aug;5(5):347-53.

PMID:
15175644
39.

The use of microarrays to study autoimmunity.

Moser KL, Gaffney PM, Grandits ME, Emamian ES, Machado DB, Baechler EC, Rhodus NL, Behrens TW.

J Investig Dermatol Symp Proc. 2004 Jan;9(1):18-22. Review.

40.

Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus.

Baechler EC, Batliwalla FM, Karypis G, Gaffney PM, Ortmann WA, Espe KJ, Shark KB, Grande WJ, Hughes KM, Kapur V, Gregersen PK, Behrens TW.

Proc Natl Acad Sci U S A. 2003 Mar 4;100(5):2610-5. Epub 2003 Feb 25.

41.

Visualizing human leukocyte antigen class II risk haplotypes in human systemic lupus erythematosus.

Graham RR, Ortmann WA, Langefeld CD, Jawaheer D, Selby SA, Rodine PR, Baechler EC, Rohlf KE, Shark KB, Espe KJ, Green LE, Nair RP, Stuart PE, Elder JT, King RA, Moser KL, Gaffney PM, Bugawan TL, Erlich HA, Rich SS, Gregersen PK, Behrens TW.

Am J Hum Genet. 2002 Sep;71(3):543-53. Epub 2002 Jul 26.

42.
43.

Genetic linkage and transmission disequilibrium of marker haplotypes at chromosome 1q41 in human systemic lupus erythematosus.

Graham RR, Langefeld CD, Gaffney PM, Ortmann WA, Selby SA, Baechler EC, Shark KB, Ockenden TC, Rohlf KE, Moser KL, Brown WM, Gabriel SE, Messner RP, King RA, Horak P, Elder JT, Stuart PE, Rich SS, Behrens TW.

Arthritis Res. 2001;3(5):299-305. Epub 2001 Jul 17.

44.

Identification and characterisation of two surface glycoproteins on cultured cerebellar cells.

Goridis C, Hirsch M, Dossetto M, Baechler E.

Brain Res. 1980 Jan 27;182(2):397-414.

PMID:
7188870

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