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Exploring the Wnt signaling pathway in schizophrenia and bipolar disorder.

Hoseth EZ, Krull F, Dieset I, Mørch RH, Hope S, Gardsjord ES, Steen NE, Melle I, Brattbakk HR, Steen VM, Aukrust P, Djurovic S, Andreassen OA, Ueland T.

Transl Psychiatry. 2018 Mar 6;8(1):55. doi: 10.1038/s41398-018-0102-1.


A Young, Immunocompetent Woman with Small Bowel and Hepatic Mucormycosis Successfully Treated with Aggressive Surgical Debridements and Antifungal Therapy.

Vikum D, Nordøy I, Torp Andersen C, Fevang B, Line PD, Kolrud FK, Aukrust P, Buanes T.

Case Rep Infect Dis. 2017;2017:4173246. doi: 10.1155/2017/4173246. Epub 2017 Dec 24.


Acute heart failure following myocardial infarction: complement activation correlates with the severity of heart failure in patients developing cardiogenic shock.

Orrem HL, Nilsson PH, Pischke SE, Grindheim G, Garred P, Seljeflot I, Husebye T, Aukrust P, Yndestad A, Andersen GØ, Barratt-Due A, Mollnes TE.

ESC Heart Fail. 2018 Feb 9. doi: 10.1002/ehf2.12266. [Epub ahead of print]


Low Levels of Immunoglobulins and Mannose-Binding Lectin Are Not Associated With Etiology, Severity, or Outcome in Community-Acquired Pneumonia.

Siljan WW, Holter JC, Nymo SH, Husebye E, Ueland T, Skattum L, Bosnes V, Garred P, Frøland SS, Mollnes TE, Aukrust P, Heggelund L.

Open Forum Infect Dis. 2018 Jan 5;5(2):ofy002. doi: 10.1093/ofid/ofy002. eCollection 2018 Feb.


Inflammatory and related biomarkers are associated with post-transplant diabetes mellitus in kidney recipients: a retrospective study.

Heldal TF, Ueland T, Jenssen T, Hartmann A, Reisaeter AV, Aukrust P, Michelsen A, Åsberg A.

Transpl Int. 2018 Jan 16. doi: 10.1111/tri.13116. [Epub ahead of print]


Osteoprotegerin Is Associated With Major Bleeding But Not With Cardiovascular Outcomes in Patients With Acute Coronary Syndromes: Insights From the PLATO (Platelet Inhibition and Patient Outcomes) Trial.

Ueland T, Åkerblom A, Ghukasyan T, Michelsen AE, Aukrust P, Becker RC, Bertilsson M, Himmelmann A, James SK, Siegbahn A, Storey RF, Kontny F, Wallentin L; PLATO (Platelet Inhibition and Patient Outcomes) Trial Investigators.

J Am Heart Assoc. 2018 Jan 12;7(2). pii: e007009. doi: 10.1161/JAHA.117.007009.


Increased Levels of Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 in Ischemic Stroke and Transient Ischemic Attack.

Skarpengland T, Skjelland M, Kong XY, Skagen K, Holm S, Otterdal K, Dahl CP, Krohg-Sørensen K, Sagen EL, Bjerkeli V, Aamodt AH, Abbas A, Gregersen I, Aukrust P, Halvorsen B, Dahl TB.

J Am Heart Assoc. 2018 Jan 12;7(2). pii: e006479. doi: 10.1161/JAHA.117.006479.


Interleukin-22 reverses human islet dysfunction and apoptosis triggered by hyperglycemia and LIGHT.

Abadpour S, Halvorsen B, Sahraoui A, Korsgren O, Aukrust P, Scholz H.

J Mol Endocrinol. 2018 Apr;60(3):171-183. doi: 10.1530/JME-17-0182. Epub 2018 Jan 12.


Immediate response in markers of inflammation and angiogenesis during exercise: a randomised cross-over study in heart transplant recipients.

Yardley M, Ueland T, Aukrust P, Michelsen A, Bjørkelund E, Gullestad L, Nytrøen K.

Open Heart. 2017 Nov 28;4(2):e000635. doi: 10.1136/openhrt-2017-000635. eCollection 2017.


Interleukin 27 is increased in carotid atherosclerosis and promotes NLRP3 inflammasome activation.

Gregersen I, Sandanger Ø, Askevold ET, Sagen EL, Yang K, Holm S, Pedersen TM, Skjelland M, Krohg-Sørensen K, Hansen TV, Dahl TB, Otterdal K, Espevik T, Aukrust P, Yndestad A, Halvorsen B.

PLoS One. 2017 Nov 27;12(11):e0188387. doi: 10.1371/journal.pone.0188387. eCollection 2017.


Cytokine responses, microbial aetiology and short-term outcome in community-acquired pneumonia.

Siljan WW, Holter JC, Nymo SH, Husebye E, Ueland T, Aukrust P, Mollnes TE, Heggelund L.

Eur J Clin Invest. 2018 Jan;48(1). doi: 10.1111/eci.12865. Epub 2017 Dec 7.


Systemic and Airway Inflammation After Exposure to Fumes from Military Small Arms.

Sikkeland LIB, Borander AK, Voie ØA, Aass HCD, Øvstebø R, Aukrust P, Longva K, Alexis NE, Kongerud J, Ueland T.

Am J Respir Crit Care Med. 2017 Nov 16. doi: 10.1164/rccm.201709-1857LE. [Epub ahead of print] No abstract available.


Bariatric surgery reduces fasting total fatty acids and increases n-3 polyunsaturated fatty acids in morbidly obese individuals.

Hovland A, Nestvold T, Bohov P, Trøseid M, Aukrust P, Berge RK, Waage-Nielsen E, Retterstøl K, Lappegård KT.

Scand J Clin Lab Invest. 2017 Dec;77(8):628-633. doi: 10.1080/00365513.2017.1393691. Epub 2017 Oct 25.


TLR9 stimulation of B-cells induces transcription of p53 and prevents spontaneous and irradiation-induced cell death independent of DNA damage responses. Implications for Common variable immunodeficiency.

Holm KL, Syljuåsen RG, Hasvold G, Alsøe L, Nilsen H, Ivanauskiene K, Collas P, Shaposhnikov S, Collins A, Indrevær RL, Aukrust P, Fevang B, Blomhoff HK.

PLoS One. 2017 Oct 3;12(10):e0185708. doi: 10.1371/journal.pone.0185708. eCollection 2017.


Comprehensive lipid and metabolite profiling of children with and without familial hypercholesterolemia: A cross-sectional study.

Christensen JJ, Ulven SM, Retterstøl K, Narverud I, Bogsrud MP, Henriksen T, Bollerslev J, Halvorsen B, Aukrust P, Holven KB.

Atherosclerosis. 2017 Nov;266:48-57. doi: 10.1016/j.atherosclerosis.2017.09.021. Epub 2017 Sep 21.


Prognostic importance of emerging cardiac, inflammatory, and renal biomarkers in chronic heart failure patients with reduced ejection fraction and anaemia: RED-HF study.

Welsh P, Kou L, Yu C, Anand I, van Veldhuisen DJ, Maggioni AP, Desai AS, Solomon SD, Pfeffer MA, Cheng S, Gullestad L, Aukrust P, Ueland T, Swedberg K, Young JB, Kattan MW, Sattar N, McMurray JJV.

Eur J Heart Fail. 2018 Feb;20(2):268-277. doi: 10.1002/ejhf.988. Epub 2017 Sep 27.


CXC chemokine ligand 16 is increased in gestational diabetes mellitus and preeclampsia and associated with lipoproteins in gestational diabetes mellitus at 5 years follow-up.

Lekva T, Michelsen AE, Aukrust P, Paasche Roland MC, Henriksen T, Bollerslev J, Ueland T.

Diab Vasc Dis Res. 2017 Nov;14(6):525-533. doi: 10.1177/1479164117728011. Epub 2017 Aug 31.


Cyclodextrin Reduces Cholesterol Crystal-Induced Inflammation by Modulating Complement Activation.

Bakke SS, Aune MH, Niyonzima N, Pilely K, Ryan L, Skjelland M, Garred P, Aukrust P, Halvorsen B, Latz E, Damås JK, Mollnes TE, Espevik T.

J Immunol. 2017 Oct 15;199(8):2910-2920. doi: 10.4049/jimmunol.1700302. Epub 2017 Aug 30.


Persistent increase in TNF and IL-1 markers in severe mental disorders suggests trait-related inflammation: a one year follow-up study.

Mørch RH, Dieset I, Faerden A, Hope S, Aas M, Nerhus M, Gardsjord ES, Haram M, Falk RS, Joa I, Morken G, Agartz I, Aukrust P, Djurovic S, Melle I, Ueland T, Andreassen OA.

Acta Psychiatr Scand. 2017 Oct;136(4):400-408. doi: 10.1111/acps.12783. Epub 2017 Aug 16.


Increased Secondary/Primary Bile Acid Ratio in Chronic Heart Failure.

Mayerhofer CCK, Ueland T, Broch K, Vincent RP, Cross GF, Dahl CP, Aukrust P, Gullestad L, Hov JR, Trøseid M.

J Card Fail. 2017 Sep;23(9):666-671. doi: 10.1016/j.cardfail.2017.06.007. Epub 2017 Jul 5.


Childhood maltreatment severity is associated with elevated C-reactive protein and body mass index in adults with schizophrenia and bipolar diagnoses.

Aas M, Dieset I, Hope S, Hoseth E, Mørch R, Reponen E, Steen NE, Laskemoen JF, Ueland T, Aukrust P, Agartz I, Andreassen OA, Melle I.

Brain Behav Immun. 2017 Oct;65:342-349. doi: 10.1016/j.bbi.2017.06.005. Epub 2017 Jun 13.


Wnt5a is associated with right ventricular dysfunction and adverse outcome in dilated cardiomyopathy.

Abraityte A, Lunde IG, Askevold ET, Michelsen AE, Christensen G, Aukrust P, Yndestad A, Fiane A, Andreassen A, Aakhus S, Dahl CP, Gullestad L, Broch K, Ueland T.

Sci Rep. 2017 Jun 14;7(1):3490. doi: 10.1038/s41598-017-03625-9.


Monocyte/macrophage and T cell activation markers are not independently associated with MI risk in healthy individuals - results from the HUNT Study.

Ueland T, Laugsand LE, Vatten LJ, Janszky I, Platou C, Michelsen AE, Damås JK, Aukrust P, Åsvold BO.

Int J Cardiol. 2017 Sep 15;243:502-504. doi: 10.1016/j.ijcard.2017.05.106. Epub 2017 Jun 12.


Severe hypertriglyceridemia in Norway: prevalence, clinical and genetic characteristics.

Retterstøl K, Narverud I, Selmer R, Berge KE, Osnes IV, Ulven SM, Halvorsen B, Aukrust P, Holven KB, Iversen PO.

Lipids Health Dis. 2017 Jun 12;16(1):115. doi: 10.1186/s12944-017-0511-9.


Associations of brain-natriuretic peptide, high-sensitive troponin T, and high-sensitive C-reactive protein with outcomes in severe aortic stenosis.

Auensen A, Hussain AI, Falk RS, Walle-Hansen MM, Bye J, Pettersen KI, Aukrust P, Ueland T, Gullestad LL.

PLoS One. 2017 Jun 12;12(6):e0179304. doi: 10.1371/journal.pone.0179304. eCollection 2017.


Elevated trimethylamine-N-oxide (TMAO) is associated with poor prognosis in primary sclerosing cholangitis patients with normal liver function.

Kummen M, Vesterhus M, Trøseid M, Moum B, Svardal A, Boberg KM, Aukrust P, Karlsen TH, Berge RK, Hov JR.

United European Gastroenterol J. 2017 Jun;5(4):532-541. doi: 10.1177/2050640616663453. Epub 2016 Aug 2.


Toll-Like Receptor 9 Promotes Survival in SERCA2a KO Heart Failure Mice.

Dhondup Y, Sjaastad I, Sandanger Ø, Aronsen JM, Ahmed MS, Attramadal H, Finsen AV, Zhang L, Ranheim T, Alfsnes K, Aukrust P, Christensen G, Yndestad A, Vinge LE.

Mediators Inflamm. 2017;2017:9450439. doi: 10.1155/2017/9450439. Epub 2017 Apr 11.


Defective IL-4 signaling in T cells defines severe common variable immunodeficiency.

Taraldsrud E, Fevang B, Jørgensen SF, Moltu K, Hilden V, Taskén K, Aukrust P, Myklebust JH, Olweus J.

J Autoimmun. 2017 Jul;81:110-119. doi: 10.1016/j.jaut.2017.04.004. Epub 2017 May 3.


The Notch Ligands DLL1 and Periostin Are Associated with Symptom Severity and Diastolic Function in Dilated Cardiomyopathy.

Norum HM, Broch K, Michelsen AE, Lunde IG, Lekva T, Abraityte A, Dahl CP, Fiane AE, Andreassen AK, Christensen G, Aakhus S, Aukrust P, Gullestad L, Ueland T.

J Cardiovasc Transl Res. 2017 Aug;10(4):401-410. doi: 10.1007/s12265-017-9748-y. Epub 2017 May 4.


Large Reduction in Adiponectin During Pregnancy Is Associated With Large-for-Gestational-Age Newborns.

Lekva T, Roland MCP, Michelsen AE, Friis CM, Aukrust P, Bollerslev J, Henriksen T, Ueland T.

J Clin Endocrinol Metab. 2017 Jul 1;102(7):2552-2559. doi: 10.1210/jc.2017-00289.


Effect of interleukin-6 inhibition on coronary microvascular and endothelial function in myocardial infarction.

Holte E, Kleveland O, Ueland T, Kunszt G, Bratlie M, Broch K, Michelsen AE, Bendz B, Amundsen BH, Aakhus S, Damås JK, Gullestad L, Aukrust P, Wiseth R.

Heart. 2017 Oct;103(19):1521-1527. doi: 10.1136/heartjnl-2016-310875. Epub 2017 Apr 21.


Extracellular matrix markers and risk of myocardial infarction: The HUNT Study in Norway.

Ueland T, Laugsand LE, Vatten LJ, Janszky I, Platou C, Michelsen AE, Damås JK, Aukrust P, Åsvold BO.

Eur J Prev Cardiol. 2017 Jul;24(11):1161-1167. doi: 10.1177/2047487317703826. Epub 2017 Apr 21.


Leukocyte Overexpression of Intracellular NAMPT Attenuates Atherosclerosis by Regulating PPARγ-Dependent Monocyte Differentiation and Function.

Bermudez B, Dahl TB, Medina I, Groeneweg M, Holm S, Montserrat-de la Paz S, Rousch M, Otten J, Herias V, Varela LM, Ranheim T, Yndestad A, Ortega-Gomez A, Abia R, Nagy L, Aukrust P, Muriana FJG, Halvorsen B, Biessen EAL.

Arterioscler Thromb Vasc Biol. 2017 Jun;37(6):1157-1167. doi: 10.1161/ATVBAHA.116.308187. Epub 2017 Apr 13.


Limited Added Value of Circulating Inflammatory Biomarkers in Chronic Heart Failure.

Nymo SH, Aukrust P, Kjekshus J, McMurray JJ, Cleland JG, Wikstrand J, Muntendam P, Wienhues-Thelen U, Latini R, Askevold ET, Gravning J, Dahl CP, Broch K, Yndestad A, Gullestad L, Ueland T; CORONA Study Group.

JACC Heart Fail. 2017 Apr;5(4):256-264. doi: 10.1016/j.jchf.2017.01.008.


Wnt5a is elevated in heart failure and affects cardiac fibroblast function.

Abraityte A, Vinge LE, Askevold ET, Lekva T, Michelsen AE, Ranheim T, Alfsnes K, Fiane A, Aakhus S, Lunde IG, Dahl CP, Aukrust P, Christensen G, Gullestad L, Yndestad A, Ueland T.

J Mol Med (Berl). 2017 Jul;95(7):767-777. doi: 10.1007/s00109-017-1529-1. Epub 2017 Mar 30.


High physical fitness is associated with reduction in basal- and exercise-induced inflammation.

Kleiven Ø, Bjørkavoll-Bergseth M, Melberg T, Skadberg Ø, Bergseth R, Selvåg J, Auestad B, Aukrust P, Aarsland T, Ørn S.

Scand J Med Sci Sports. 2018 Jan;28(1):172-179. doi: 10.1111/sms.12878. Epub 2017 Apr 12.


Osteoprotegerin levels in ST-elevation myocardial infarction: Temporal profile and association with myocardial injury and left ventricular function.

Shetelig C, Limalanathan S, Eritsland J, Hoffmann P, Seljeflot I, Gran JM, Aukrust P, Ueland T, Andersen GØ.

PLoS One. 2017 Mar 2;12(3):e0173034. doi: 10.1371/journal.pone.0173034. eCollection 2017.


Adaptive NK cells can persist in patients with GATA2 mutation depleted of stem and progenitor cells.

Schlums H, Jung M, Han H, Theorell J, Bigley V, Chiang SC, Allan DS, Davidson-Moncada JK, Dickinson RE, Holmes TD, Hsu AP, Townsley D, Winkler T, Wang W, Aukrust P, Nordøy I, Calvo KR, Holland SM, Collin M, Dunbar CE, Bryceson YT.

Blood. 2017 Apr 6;129(14):1927-1939. doi: 10.1182/blood-2016-08-734236. Epub 2017 Feb 16.


The alternative complement pathway is dysregulated in patients with chronic heart failure.

Shahini N, Michelsen AE, Nilsson PH, Ekholt K, Gullestad L, Broch K, Dahl CP, Aukrust P, Ueland T, Mollnes TE, Yndestad A, Louwe MC.

Sci Rep. 2017 Feb 14;7:42532. doi: 10.1038/srep42532.


CVID and Celiac Disease.

Jørgensen SF, Reims HM, Aukrust P, Lundin KE, Fevang B.

Am J Gastroenterol. 2017 Feb;112(2):393. doi: 10.1038/ajg.2016.551. No abstract available.


Data on circulating leukocyte subpopulations and inflammatory proteins in children with familial hypercholesterolemia and healthy children.

Christensen JJ, Osnes L, Halvorsen B, Retterstøl K, Bogsrud MP, Wium C, Svilaas A, Narverud I, Ulven SM, Aukrust P, Holven KB.

Data Brief. 2016 Dec 29;10:587-592. doi: 10.1016/j.dib.2016.12.042. eCollection 2017 Feb.


Leptin and adiponectin as predictors of cardiovascular risk after gestational diabetes mellitus.

Lekva T, Michelsen AE, Aukrust P, Henriksen T, Bollerslev J, Ueland T.

Cardiovasc Diabetol. 2017 Jan 10;16(1):5. doi: 10.1186/s12933-016-0492-4.


NEIL3-Dependent Regulation of Cardiac Fibroblast Proliferation Prevents Myocardial Rupture.

Olsen MB, Hildrestrand GA, Scheffler K, Vinge LE, Alfsnes K, Palibrk V, Wang J, Neurauter CG, Luna L, Johansen J, Øgaard JDS, Ohm IK, Slupphaug G, Kuśnierczyk A, Fiane AE, Brorson SH, Zhang L, Gullestad L, Louch WE, Iversen PO, Østlie I, Klungland A, Christensen G, Sjaastad I, Sætrom P, Yndestad A, Aukrust P, Bjørås M, Finsen AV.

Cell Rep. 2017 Jan 3;18(1):82-92. doi: 10.1016/j.celrep.2016.12.009.


A Study of TNF Pathway Activation in Schizophrenia and Bipolar Disorder in Plasma and Brain Tissue.

Hoseth EZ, Ueland T, Dieset I, Birnbaum R, Shin JH, Kleinman JE, Hyde TM, Mørch RH, Hope S, Lekva T, Abraityte AJ, Michelsen AE, Melle I, Westlye LT, Ueland T, Djurovic S, Aukrust P, Weinberger DR, Andreassen OA.

Schizophr Bull. 2017 Jul 1;43(4):881-890. doi: 10.1093/schbul/sbw183.


Altered leukocyte distribution under hypercholesterolemia: A cross-sectional study in children with familial hypercholesterolemia.

Christensen JJ, Osnes LT, Halvorsen B, Retterstøl K, Bogsrud MP, Wium C, Svilaas A, Narverud I, Ulven SM, Aukrust P, Holven KB.

Atherosclerosis. 2017 Jan;256:67-74. doi: 10.1016/j.atherosclerosis.2016.11.031. Epub 2016 Dec 1.


Liver transplantation in patients with primary antibody deficiency.

Jørgensen SF, Macpherson ME, Bjøro K, Karlsen TH, Reims HM, Grzyb K, Fosby B, Fevang B, Aukrust P, Nordøy I.

J Allergy Clin Immunol. 2017 May;139(5):1708-1710.e2. doi: 10.1016/j.jaci.2016.10.025. Epub 2016 Dec 6. No abstract available.


Serum osteoprotegrin (OPG) in subclinical atherosclerosis in systemic lupus erythematosus.

Kiani AN, Aukrust P, Ueland T, Hollan I, Barr E, Magder LS, Petri M.

Lupus. 2017 Jul;26(8):865-870. doi: 10.1177/0961203316682101. Epub 2016 Dec 6.


Patterns of constitutively phosphorylated kinases in B cells are associated with disease severity in common variable immunodeficiency.

Taraldsrud E, Aukrust P, Jørgensen S, Lingjærde OC, Olweus J, Myklebust JH, Fevang B.

Clin Immunol. 2017 Feb;175:69-74. doi: 10.1016/j.clim.2016.11.014. Epub 2016 Dec 3.


A potential founder variant in CARMIL2/RLTPR in three Norwegian families with warts, molluscum contagiosum, and T-cell dysfunction.

Sorte HS, Osnes LT, Fevang B, Aukrust P, Erichsen HC, Backe PH, Abrahamsen TG, Kittang OB, Øverland T, Jhangiani SN, Muzny DM, Vigeland MD, Samarakoon P, Gambin T, Akdemir ZH, Gibbs RA, Rødningen OK, Lyle R, Lupski JR, Stray-Pedersen A.

Mol Genet Genomic Med. 2016 Sep 17;4(6):604-616. eCollection 2016 Nov.


Palmitate promotes inflammatory responses and cellular senescence in cardiac fibroblasts.

Sokolova M, Vinge LE, Alfsnes K, Olsen MB, Eide L, Kaasbøll OJ, Attramadal H, Torp MK, Fosshaug LE, Rashidi A, Lien E, Finsen AV, Sandanger Ø, Aukrust P, Ranheim T, Yndestad A.

Biochim Biophys Acta. 2017 Feb;1862(2):234-245. doi: 10.1016/j.bbalip.2016.11.003. Epub 2016 Nov 12.


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