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Items: 1 to 50 of 156

1.

IMMUNOHISTOCHEMICAL EXPRESSION OF CORTACTIN AND FOCAL ADHESION KINASE PREDICTS RECURRENCE RISK AND LARYNGEAL CANCER RISK BEYOND HISTOLOGICAL GRADING.

Villaronga MÁ, Hermida-Prado F, Granda-Diaz R, Menendez ST, Alvarez-Teijeiro S, Quer M, Vilaseca I, Allonca E, Garzón-Arango M, Sanz-Moreno V, Astudillo A, Rodrigo JP, García-Pedrero JM.

Cancer Epidemiol Biomarkers Prev. 2018 Apr 13. pii: cebp.1082.2017. doi: 10.1158/1055-9965.EPI-17-1082. [Epub ahead of print]

PMID:
29654156
2.

Immunophenotypic features of dedifferentiated skull base chordoma: An insight into the intratumoural heterogeneity.

Batista KMP, Reyes KYA, Lopez FP, Pelaz AC, Vega IF, Pendás JLL, Ayala AS, Astudillo A, Rojas JAN, Fernandez PB.

Contemp Oncol (Pozn). 2017;21(4):267-273. doi: 10.5114/wo.2017.72385. Epub 2017 Dec 30. Review.

3.

Nebulization effects on structural stability of bacteriophage PEV 44.

Astudillo A, Leung SSY, Kutter E, Morales S, Chan HK.

Eur J Pharm Biopharm. 2018 Apr;125:124-130. doi: 10.1016/j.ejpb.2018.01.010. Epub 2018 Jan 17.

PMID:
29353018
4.

TP53 p.R72P genotype is a marker of poor prognosis in lung cancer.

Neumann MP, González MV, Pitiot AS, Santamaría Í, Martínez C, Tardón A, Astudillo A, Balbín M.

Cancer Biomark. 2018;21(4):747-754. doi: 10.3233/CBM-170230.

PMID:
29286914
5.

Loss of the deubiquitinase USP36 destabilizes the RNA helicase DHX33 and causes preimplantation lethality in mice.

Fraile JM, Campos-Iglesias D, Rodríguez F, Astudillo A, Vilarrasa-Blasi R, Verdaguer-Dot N, Prado MA, Paulo JA, Gygi SP, Martín-Subero JI, Freije JMP, López-Otín C.

J Biol Chem. 2018 Feb 9;293(6):2183-2194. doi: 10.1074/jbc.M117.788430. Epub 2017 Dec 22.

PMID:
29273634
6.

FUS-CHOP Promotes Invasion in Myxoid Liposarcoma through a SRC/FAK/RHO/ROCK-Dependent Pathway.

Tornin J, Hermida-Prado F, Padda RS, Gonzalez MV, Alvarez-Fernandez C, Rey V, Martinez-Cruzado L, Estupiñan O, Menendez ST, Fernandez-Nevado L, Astudillo A, Rodrigo JP, Lucien F, Kim Y, Leong HS, Garcia-Pedrero JM, Rodriguez R.

Neoplasia. 2018 Jan;20(1):44-56. doi: 10.1016/j.neo.2017.11.004. Epub 2017 Nov 28.

7.

[Protocol for the study of bone tumours and standardization of pathology reports].

Machado I, Pozo JJ, Marcilla D, Cruz J, Tardío JC, Astudillo A, Bagué S.

Rev Esp Patol. 2017 Jan - Mar;50(1):34-44. doi: 10.1016/j.patol.2016.08.003. Epub 2016 Oct 20. Spanish.

PMID:
29179963
8.

Occurrence and biological activity of palmitoleic acid isomers in phagocytic cells.

Astudillo AM, Meana C, Guijas C, Pereira L, Lebrero P, Balboa MA, Balsinde J.

J Lipid Res. 2018 Feb;59(2):237-249. doi: 10.1194/jlr.M079145. Epub 2017 Nov 21.

PMID:
29167413
9.

SDHC Promoter Methylation, a Novel Pathogenic Mechanism in Parasympathetic Paragangliomas.

Bernardo-Castiñeira C, Valdés N, Sierra MI, Sáenz-de-Santa-María I, Bayón GF, Perez RF, Fernández AF, Fraga MF, Astudillo A, Menéndez R, Fernández B, Del Olmo M, Suarez C, Chiara MD.

J Clin Endocrinol Metab. 2018 Jan 1;103(1):295-305. doi: 10.1210/jc.2017-01702.

PMID:
29126304
10.

Essential Role for Ethanolamine Plasmalogen Hydrolysis in Bacterial Lipopolysaccharide Priming of Macrophages for Enhanced Arachidonic Acid Release.

Gil-de-Gómez L, Astudillo AM, Lebrero P, Balboa MA, Balsinde J.

Front Immunol. 2017 Sep 29;8:1251. doi: 10.3389/fimmu.2017.01251. eCollection 2017.

11.

A Novel Role For Nanog As An Early Cancer Risk Marker In Patients With Laryngeal Precancerous Lesions.

Rodrigo JP, Villaronga MÁ, Menéndez ST, Hermida-Prado F, Quer M, Vilaseca I, Allonca E, Pedregal Mallo D, Astudillo A, García-Pedrero JM.

Sci Rep. 2017 Sep 11;7(1):11110. doi: 10.1038/s41598-017-11709-9.

12.

Descriptive epidemiology of primary malignant and non-malignant central nervous tumors in Spain: Results from the Girona Cancer Registry (1994-2013).

Fuentes-Raspall R, Solans M, Roca-Barceló A, Vilardell L, Puigdemont M, Del Barco S, Comas R, García-Velasco A, Astudillo A, Carmona-Garcia MC, Marcos-Gragera R.

Cancer Epidemiol. 2017 Oct;50(Pt A):1-8. doi: 10.1016/j.canep.2017.07.005. Epub 2017 Jul 21.

PMID:
28738268
13.

[Evaluation of mortality after the analysis of the screening history in women diagnosed with infiltrating cervical cancer].

Castillo M, Astudillo A, Clavero O, Velasco J, Ibáñez R, de Sanjosé S.

Aten Primaria. 2018 Mar;50(3):151-158. doi: 10.1016/j.aprim.2017.02.007. Epub 2017 Jun 16. Spanish.

14.

Trabectedin and Campthotecin Synergistically Eliminate Cancer Stem Cells in Cell-of-Origin Sarcoma Models.

Martinez-Cruzado L, Tornin J, Rodriguez A, Santos L, Allonca E, Fernandez-Garcia MT, Astudillo A, Garcia-Pedrero JM, Rodriguez R.

Neoplasia. 2017 Jun;19(6):460-470. doi: 10.1016/j.neo.2017.03.004. Epub 2017 May 8.

15.

Epidermal growth factor receptor and epididymis invasion as prognostic biomarkers in clinical stage I testicular germ cell tumours.

Sanmamed MF, Esteban E, Uriol E, Zarate R, Capelan M, Muriel C, Crespo G, Berros JP, Pardo-Coto P, Perez Q, Alvarez-Fernández C, Jiménez Fonseca P, Luque M, Astudillo A.

J Transl Med. 2017 Mar 20;15(1):62. doi: 10.1186/s12967-017-1162-3.

16.

A single-copy Sleeping Beauty transposon mutagenesis screen identifies new PTEN-cooperating tumor suppressor genes.

de la Rosa J, Weber J, Friedrich MJ, Li Y, Rad L, Ponstingl H, Liang Q, de Quirós SB, Noorani I, Metzakopian E, Strong A, Li MA, Astudillo A, Fernández-García MT, Fernández-García MS, Hoffman GJ, Fuente R, Vassiliou GS, Rad R, López-Otín C, Bradley A, Cadiñanos J.

Nat Genet. 2017 May;49(5):730-741. doi: 10.1038/ng.3817. Epub 2017 Mar 20.

17.

Clinically relevant HIF-1α-dependent metabolic reprogramming in oropharyngeal squamous cell carcinomas includes coordinated activation of CAIX and the miR-210/ISCU signaling axis, but not MCT1 and MCT4 upregulation.

Sáenz-de-Santa-María I, Bernardo-Castiñeira C, Secades P, Bernaldo-de-Quirós S, Rodrigo JP, Astudillo A, Chiara MD.

Oncotarget. 2017 Feb 21;8(8):13730-13746. doi: 10.18632/oncotarget.14629.

18.

Role of VHL, HIF1A and SDH on the expression of miR-210: Implications for tumoral pseudo-hypoxic fate.

Merlo A, Bernardo-Castiñeira C, Sáenz-de-Santa-María I, Pitiot AS, Balbín M, Astudillo A, Valdés N, Scola B, Del Toro R, Méndez-Ferrer S, Piruat JI, Suarez C, Chiara MD.

Oncotarget. 2017 Jan 24;8(4):6700-6717. doi: 10.18632/oncotarget.14265.

19.

Poor Cervical Cancer Screening Attendance and False Negatives. A Call for Organized Screening.

Castillo M, Astudillo A, Clavero O, Velasco J, Ibáñez R, de Sanjosé S.

PLoS One. 2016 Aug 22;11(8):e0161403. doi: 10.1371/journal.pone.0161403. eCollection 2016.

20.

Left ventricle non-compaction: The still misdiagnosed cardiomyopathy.

Lorca R, Martín M, Reguero JJ, Díaz-Molina B, Morís C, Lambert JL, Astudillo A.

Int J Cardiol. 2016 Nov 15;223:420-421. doi: 10.1016/j.ijcard.2016.08.200. Epub 2016 Aug 12. No abstract available.

PMID:
27544597
21.

Prevalence of human papillomavirus in oral squamous cell carcinomas in northern Spain.

Rodríguez-Santamarta T, Rodrigo JP, García-Pedrero JM, Álvarez-Teijeiro S, Ángeles Villaronga M, Suárez-Fernández L, Alvarez-Argüelles ME, Astudillo A, de Vicente JC.

Eur Arch Otorhinolaryngol. 2016 Dec;273(12):4549-4559. doi: 10.1007/s00405-016-4152-9. Epub 2016 Jun 24.

PMID:
27342404
22.

Critical role for cytosolic group IVA phospholipase A2 in early adipocyte differentiation and obesity.

Peña L, Meana C, Astudillo AM, Lordén G, Valdearcos M, Sato H, Murakami M, Balsinde J, Balboa MA.

Biochim Biophys Acta. 2016 Sep;1861(9 Pt A):1083-1095. doi: 10.1016/j.bbalip.2016.06.004. Epub 2016 Jun 16.

PMID:
27317983
23.

Foamy Monocytes Are Enriched in cis-7-Hexadecenoic Fatty Acid (16:1n-9), a Possible Biomarker for Early Detection of Cardiovascular Disease.

Guijas C, Meana C, Astudillo AM, Balboa MA, Balsinde J.

Cell Chem Biol. 2016 Jun 23;23(6):689-99. doi: 10.1016/j.chembiol.2016.04.012. Epub 2016 Jun 2.

24.

Analysis of Olig2 and YKL-40 expression: a clinicopathological/immunohistochemical study for the distinction between subventricular zone II and III glioblastomas.

Batista K, Costa B, Pablo I, Vega IF, Morales J, Alvarez AV, Meilán A, Astudillo A, Alvarez KY.

Folia Neuropathol. 2016;54(1):31-9.

25.

Impact of PI3K/AKT/mTOR pathway activation on the prognosis of patients with head and neck squamous cell carcinomas.

García-Carracedo D, Villaronga MÁ, Álvarez-Teijeiro S, Hermida-Prado F, Santamaría I, Allonca E, Suárez-Fernández L, Gonzalez MV, Balbín M, Astudillo A, Martínez-Camblor P, Su GH, Rodrigo JP, García-Pedrero JM.

Oncotarget. 2016 May 17;7(20):29780-93. doi: 10.18632/oncotarget.8957.

26.

Inhibition of SP1 by the mithramycin analog EC-8042 efficiently targets tumor initiating cells in sarcoma.

Tornin J, Martinez-Cruzado L, Santos L, Rodriguez A, Núñez LE, Oro P, Hermosilla MA, Allonca E, Fernández-García MT, Astudillo A, Suarez C, Morís F, Rodriguez R.

Oncotarget. 2016 May 24;7(21):30935-50. doi: 10.18632/oncotarget.8817.

27.

Expression of p16/Ki-67 in ASC-US/LSIL or Normal Cytology with Presence of Oncogenic HPV DNA.

Solares C, Velasco J, Álvarez-Ruiz E, González-Fernández L, Encinas AI, Astudillo A, Schneider J.

Anticancer Res. 2015 Nov;35(11):6291-5.

PMID:
26504065
28.

Clinical significance of Anoctamin-1 gene at 11q13 in the development and progression of head and neck squamous cell carcinomas.

Rodrigo JP, Menéndez ST, Hermida-Prado F, Álvarez-Teijeiro S, Villaronga MÁ, Alonso-Durán L, Vallina A, Martínez-Camblor P, Astudillo A, Suárez C, María García-Pedrero J.

Sci Rep. 2015 Oct 26;5:15698. doi: 10.1038/srep15698.

29.

Heparan sulfate proteoglycans undergo differential expression alterations in right sided colorectal cancer, depending on their metastatic character.

Fernández-Vega I, García-Suárez O, García B, Crespo A, Astudillo A, Quirós LM.

BMC Cancer. 2015 Oct 20;15:742. doi: 10.1186/s12885-015-1724-9.

30.

Heparanase and heparanase 2 display differently deregulation in neuroendocrine tumors, depending on their differentiation grade.

García B, García-Suárez O, Fernández-Vega I, Vallina A, Astudillo A, Quirós LM.

Histol Histopathol. 2016 Jan;31(1):73-81. doi: 10.14670/HH-11-650. Epub 2015 Jul 31.

PMID:
26230211
31.

Activation of Lysophosphatidic Acid Receptor Type 1 Contributes to Pathophysiology of Spinal Cord Injury.

Santos-Nogueira E, López-Serrano C, Hernández J, Lago N, Astudillo AM, Balsinde J, Estivill-Torrús G, de Fonseca FR, Chun J, López-Vales R.

J Neurosci. 2015 Jul 15;35(28):10224-35. doi: 10.1523/JNEUROSCI.4703-14.2015.

32.

64 Year-Old Woman with Longstanding Migraine. Primary Diffuse Leptomeningeal Gliomatosis (PDLG) (WHO Grade III).

Fernandez-Vega I, Saiz A, Santos-Juanes J, Piña-Batista K, Corte-Torres MD, Astudillo A.

Brain Pathol. 2015 May;25(3):365-6. No abstract available.

PMID:
26086054
33.

Merkel cell carcinoma and Merkel cell polyomavirus: a systematic review and meta-analysis.

Santos-Juanes J, Fernández-Vega I, Fuentes N, Galache C, Coto-Segura P, Vivanco B, Astudillo A, Martínez-Camblor P.

Br J Dermatol. 2015 Jul;173(1):42-9. doi: 10.1111/bjd.13870. Epub 2015 Jun 12. Review.

PMID:
25919492
34.

Prognostic significance of the markers IDH1 and YKL40 related to the subventricular zone.

Pińa Batista KM, Vega IF, de Eulate-Beramendi SA, Morales J, Kurbanov A, Asnel D, Meilan A, Astudillo A.

Folia Neuropathol. 2015;53(1):52-9.

35.

Gut microbiome compositional and functional differences between tumor and non-tumor adjacent tissues from cohorts from the US and Spain.

Allali I, Delgado S, Marron PI, Astudillo A, Yeh JJ, Ghazal H, Amzazi S, Keku T, Azcarate-Peril MA.

Gut Microbes. 2015;6(3):161-72. doi: 10.1080/19490976.2015.1039223.

36.

Manganese superoxide dismutase (SOD2/MnSOD)/catalase and SOD2/GPx1 ratios as biomarkers for tumor progression and metastasis in prostate, colon, and lung cancer.

Miar A, Hevia D, Muñoz-Cimadevilla H, Astudillo A, Velasco J, Sainz RM, Mayo JC.

Free Radic Biol Med. 2015 Aug;85:45-55. doi: 10.1016/j.freeradbiomed.2015.04.001. Epub 2015 Apr 10.

PMID:
25866291
37.

Prognostic and diagnostic value of epithelial to mesenchymal transition markers in pulmonary neuroendocrine tumors.

Galván JA, Astudillo A, Vallina A, Crespo G, Folgueras MV, González MV.

BMC Cancer. 2014 Nov 20;14:855. doi: 10.1186/1471-2407-14-855.

38.

Mutations in filamin C cause a new form of familial hypertrophic cardiomyopathy.

Valdés-Mas R, Gutiérrez-Fernández A, Gómez J, Coto E, Astudillo A, Puente DA, Reguero JR, Álvarez V, Morís C, León D, Martín M, Puente XS, López-Otín C.

Nat Commun. 2014 Oct 29;5:5326. doi: 10.1038/ncomms6326.

PMID:
25351925
39.

Prognostic relevance of estrogen receptor-α Ser167 phosphorylation in stage II-III colon cancer patients.

López-Calderero I, Carnero A, Astudillo A, Palacios J, Chaves M, Benavent M, Limón ML, Garcia-Carbonero R.

Hum Pathol. 2014 Dec;45(12):2437-46. doi: 10.1016/j.humpath.2014.08.008. Epub 2014 Sep 2.

PMID:
25283475
40.

Role of connexin channels in the retinal light response of a diurnal rodent.

Palacios-Muñoz A, Escobar MJ, Vielma A, Araya J, Astudillo A, Valdivia G, García IE, Hurtado J, Schmachtenberg O, Martínez AD, Palacios AG.

Front Cell Neurosci. 2014 Aug 25;8:249. doi: 10.3389/fncel.2014.00249. eCollection 2014.

41.

ASMase regulates autophagy and lysosomal membrane permeabilization and its inhibition prevents early stage non-alcoholic steatohepatitis.

Fucho R, Martínez L, Baulies A, Torres S, Tarrats N, Fernandez A, Ribas V, Astudillo AM, Balsinde J, Garcia-Rovés P, Elena M, Bergheim I, Lotersztajn S, Trautwein C, Appelqvist H, Paton AW, Paton JC, Czaja MJ, Kaplowitz N, Fernandez-Checa JC, García-Ruiz C.

J Hepatol. 2014 Nov;61(5):1126-34. doi: 10.1016/j.jhep.2014.06.009. Epub 2014 Jun 16.

42.

Neuroendocrine tumors show altered expression of chondroitin sulfate, glypican 1, glypican 5, and syndecan 2 depending on their differentiation grade.

García-Suárez O, García B, Fernández-Vega I, Astudillo A, Quirós LM.

Front Oncol. 2014 Feb 7;4:15. doi: 10.3389/fonc.2014.00015. eCollection 2014.

43.

Defective autophagy impairs ATF3 activity and worsens lung injury during endotoxemia.

Aguirre A, López-Alonso I, González-López A, Amado-Rodríguez L, Batalla-Solís E, Astudillo A, Blázquez-Prieto J, Fernández AF, Galván JA, dos Santos CC, Albaiceta GM.

J Mol Med (Berl). 2014 Jun;92(6):665-76. doi: 10.1007/s00109-014-1132-7. Epub 2014 Feb 19.

PMID:
24535031
44.

Bone environment is essential for osteosarcoma development from transformed mesenchymal stem cells.

Rubio R, Abarrategi A, Garcia-Castro J, Martinez-Cruzado L, Suarez C, Tornin J, Santos L, Astudillo A, Colmenero I, Mulero F, Rosu-Myles M, Menendez P, Rodriguez R.

Stem Cells. 2014 May;32(5):1136-48. doi: 10.1002/stem.1647.

45.

Molecular biology of neuroendocrine tumors: from pathways to biomarkers and targets.

Capdevila J, Meeker A, García-Carbonero R, Pietras K, Astudillo A, Casanovas O, Scarpa A.

Cancer Metastasis Rev. 2014 Mar;33(1):345-51. doi: 10.1007/s10555-013-9468-y. Review.

PMID:
24375391
46.

Immunohistochemical markers of distant metastasis in laryngeal and hypopharyngeal squamous cell carcinomas.

Rodrigo JP, Martínez P, Allonca E, Alonso-Durán L, Suárez C, Astudillo A, García-Pedrero JM.

Clin Exp Metastasis. 2014 Mar;31(3):317-25. doi: 10.1007/s10585-013-9630-5. Epub 2013 Dec 27.

PMID:
24370715
47.

Cardiotrophin-1 eliminates hepatic steatosis in obese mice by mechanisms involving AMPK activation.

Castaño D, Larequi E, Belza I, Astudillo AM, Martínez-Ansó E, Balsinde J, Argemi J, Aragon T, Moreno-Aliaga MJ, Muntane J, Prieto J, Bustos M.

J Hepatol. 2014 May;60(5):1017-25. doi: 10.1016/j.jhep.2013.12.012. Epub 2013 Dec 19.

PMID:
24362075
48.

Cytosolic group IVA and calcium-independent group VIA phospholipase A2s act on distinct phospholipid pools in zymosan-stimulated mouse peritoneal macrophages.

Gil-de-Gómez L, Astudillo AM, Guijas C, Magrioti V, Kokotos G, Balboa MA, Balsinde J.

J Immunol. 2014 Jan 15;192(2):752-62. doi: 10.4049/jimmunol.1302267. Epub 2013 Dec 13.

49.

Identification of novel tumor suppressor proteases by degradome profiling of colorectal carcinomas.

Fraile JM, Ordóñez GR, Quirós PM, Astudillo A, Galván JA, Colomer D, López-Otín C, Freije JM, Puente XS.

Oncotarget. 2013 Nov;4(11):1931-2.

50.

Cell-cell adhesion genes CTNNA2 and CTNNA3 are tumour suppressors frequently mutated in laryngeal carcinomas.

Fanjul-Fernández M, Quesada V, Cabanillas R, Cadiñanos J, Fontanil T, Obaya A, Ramsay AJ, Llorente JL, Astudillo A, Cal S, López-Otín C.

Nat Commun. 2013;4:2531. doi: 10.1038/ncomms3531.

PMID:
24100690

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