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Items: 1 to 50 of 310

1.

Microfluidic Approaches for the Characterization of Therapeutic Proteins.

Kopp MRG, Arosio P.

J Pharm Sci. 2018 Jan 8. pii: S0022-3549(18)30001-7. doi: 10.1016/j.xphs.2018.01.001. [Epub ahead of print] Review.

PMID:
29325925
2.

Microfluidics for Protein Biophysics.

Charmet J, Arosio P, Knowles TPJ.

J Mol Biol. 2017 Dec 29. pii: S0022-2836(17)30603-4. doi: 10.1016/j.jmb.2017.12.015. [Epub ahead of print] Review.

PMID:
29289566
3.

Sinus augmentation and concomitant implant placement in low bone-density sites. A retrospective study on an undersized drilling protocol and primary stability.

Arosio P, Greco GB, Zaniol T, Iezzi G, Perrotti V, Di Stefano DA.

Clin Implant Dent Relat Res. 2017 Nov 22. doi: 10.1111/cid.12558. [Epub ahead of print]

PMID:
29164788
4.

Mechanistic Origin of the Combined Effect of Surfaces and Mechanical Agitation on Amyloid Formation.

Grigolato F, Colombo C, Ferrari R, Rezabkova L, Arosio P.

ACS Nano. 2017 Nov 28;11(11):11358-11367. doi: 10.1021/acsnano.7b05895. Epub 2017 Oct 25.

PMID:
29045787
5.
6.

Effect of chaotropes on the kinetics of iron release from ferritin by flavin nucleotides.

Johnson LE, Wilkinson T, Arosio P, Melman A, Bou-Abdallah F.

Biochim Biophys Acta. 2017 Dec;1861(12):3257-3262. doi: 10.1016/j.bbagen.2017.09.016. Epub 2017 Sep 21.

PMID:
28943300
7.

Expression and characterization of the ferritin binding domain of Nuclear Receptor Coactivator-4 (NCOA4).

Gryzik M, Srivastava A, Longhi G, Bertuzzi M, Gianoncelli A, Carmona F, Poli M, Arosio P.

Biochim Biophys Acta. 2017 Nov;1861(11 Pt A):2710-2716. doi: 10.1016/j.bbagen.2017.07.015. Epub 2017 Jul 25.

PMID:
28754384
8.

Selective targeting of primary and secondary nucleation pathways in Aβ42 aggregation using a rational antibody scanning method.

Aprile FA, Sormanni P, Perni M, Arosio P, Linse S, Knowles TPJ, Dobson CM, Vendruscolo M.

Sci Adv. 2017 Jun 21;3(6):e1700488. doi: 10.1126/sciadv.1700488. eCollection 2017 Jun.

9.

The insertion torque-depth curve integral as a measure of implant primary stability: An in vitro study on polyurethane foam blocks.

Di Stefano DA, Arosio P, Gastaldi G, Gherlone E.

J Prosthet Dent. 2017 Jul 8. pii: S0022-3913(17)30300-1. doi: 10.1016/j.prosdent.2017.04.012. [Epub ahead of print]

PMID:
28689908
10.

Iron Oxidation and Core Formation in Recombinant Heteropolymeric Human Ferritins.

Mehlenbacher M, Poli M, Arosio P, Santambrogio P, Levi S, Chasteen ND, Bou-Abdallah F.

Biochemistry. 2017 Aug 1;56(30):3900-3912. doi: 10.1021/acs.biochem.7b00024. Epub 2017 Jul 18.

PMID:
28636371
11.

Phage display and kinetic selection of antibodies that specifically inhibit amyloid self-replication.

Munke A, Persson J, Weiffert T, De Genst E, Meisl G, Arosio P, Carnerup A, Dobson CM, Vendruscolo M, Knowles TPJ, Linse S.

Proc Natl Acad Sci U S A. 2017 Jun 20;114(25):6444-6449. doi: 10.1073/pnas.1700407114. Epub 2017 Jun 5.

12.

Self-assembling peptide and protein amyloids: from structure to tailored function in nanotechnology.

Wei G, Su Z, Reynolds NP, Arosio P, Hamley IW, Gazit E, Mezzenga R.

Chem Soc Rev. 2017 Jul 31;46(15):4661-4708. doi: 10.1039/c6cs00542j. Review.

PMID:
28530745
13.

Non-Anticoagulant Heparins Are Hepcidin Antagonists for the Treatment of Anemia.

Poli M, Asperti M, Ruzzenenti P, Naggi A, Arosio P.

Molecules. 2017 Apr 8;22(4). pii: E598. doi: 10.3390/molecules22040598. Review.

14.

PEGylated Anionic Magnetofluorescent Nanoassemblies: Impact of Their Interface Structure on Magnetic Resonance Imaging Contrast and Cellular Uptake.

Linot C, Poly J, Boucard J, Pouliquen D, Nedellec S, Hulin P, Marec N, Arosio P, Lascialfari A, Guerrini A, Sangregorio C, Lecouvey M, Lartigue L, Blanquart C, Ishow E.

ACS Appl Mater Interfaces. 2017 Apr 26;9(16):14242-14257. doi: 10.1021/acsami.7b01737. Epub 2017 Apr 17.

15.

Ferritin, cellular iron storage and regulation.

Arosio P, Elia L, Poli M.

IUBMB Life. 2017 Jun;69(6):414-422. doi: 10.1002/iub.1621. Epub 2017 Mar 27. Review.

PMID:
28349628
16.

Inhibition of α-Synuclein Fibril Elongation by Hsp70 Is Governed by a Kinetic Binding Competition between α-Synuclein Species.

Aprile FA, Arosio P, Fusco G, Chen SW, Kumita JR, Dhulesia A, Tortora P, Knowles TP, Vendruscolo M, Dobson CM, Cremades N.

Biochemistry. 2017 Mar 7;56(9):1177-1180. doi: 10.1021/acs.biochem.6b01178. Epub 2017 Feb 23.

PMID:
28230968
17.

Local spin dynamics of iron oxide magnetic nanoparticles dispersed in different solvents with variable size and shape: A 1H NMR study.

Basini M, Orlando T, Arosio P, Casula MF, Espa D, Murgia S, Sangregorio C, Innocenti C, Lascialfari A.

J Chem Phys. 2017 Jan 21;146(3):034703. doi: 10.1063/1.4973979.

18.

Mitochondrial ferritin deficiency reduces male fertility in mice.

Maccarinelli F, Regoni M, Carmona F, Poli M, Meyron-Holtz EG, Arosio P.

Reprod Fertil Dev. 2017 Sep;29(10):2005-2010. doi: 10.1071/RD16348.

PMID:
28063464
19.

Systematic development of small molecules to inhibit specific microscopic steps of Aβ42 aggregation in Alzheimer's disease.

Habchi J, Chia S, Limbocker R, Mannini B, Ahn M, Perni M, Hansson O, Arosio P, Kumita JR, Challa PK, Cohen SI, Linse S, Dobson CM, Knowles TP, Vendruscolo M.

Proc Natl Acad Sci U S A. 2017 Jan 10;114(2):E200-E208. doi: 10.1073/pnas.1615613114. Epub 2016 Dec 23.

20.

Study of ferritin self-assembly and heteropolymer formation by the use of Fluorescence Resonance Energy Transfer (FRET) technology.

Carmona F, Poli M, Bertuzzi M, Gianoncelli A, Gangemi F, Arosio P.

Biochim Biophys Acta. 2017 Mar;1861(3):522-532. doi: 10.1016/j.bbagen.2016.12.011. Epub 2016 Dec 18.

PMID:
27993659
21.

Production and characterization of functional recombinant hybrid heteropolymers of camel hepcidin and human ferritin H and L chains.

Boumaiza M, Carmona F, Poli M, Asperti M, Gianoncelli A, Bertuzzi M, Ruzzenenti P, Arosio P, Marzouki MN.

Protein Eng Des Sel. 2017 Feb;30(2):77-84. doi: 10.1093/protein/gzw066. Epub 2016 Dec 15.

PMID:
27980120
22.

Heparanase Overexpression Reduces Hepcidin Expression, Affects Iron Homeostasis and Alters the Response to Inflammation.

Asperti M, Stuemler T, Poli M, Gryzik M, Lifshitz L, Meyron-Holtz EG, Vlodavsky I, Arosio P.

PLoS One. 2016 Oct 6;11(10):e0164183. doi: 10.1371/journal.pone.0164183. eCollection 2016.

23.

Correlation Between Bone Density and Instantaneous Torque at Implant Site Preparation: A Validation on Polyurethane Foam Blocks of a Device Assessing Density of Jawbones.

Di Stefano DA, Arosio P.

Int J Oral Maxillofac Implants. 2016 Sep-Oct;31(5):e128-35. doi: 10.11607/jomi.4475.

PMID:
27632279
24.

Recombinant overexpression of camel hepcidin cDNA in Pichia pastoris: purification and characterization of the polyHis-tagged peptide HepcD-His.

Boumaiza M, Chahed H, Ezzine A, Jaouan M, Gianoncelli A, Longhi G, Carmona F, Arosio P, Sari MA, Marzouki MN.

J Mol Recognit. 2017 Jan;30(1). doi: 10.1002/jmr.2561. Epub 2016 Aug 10.

PMID:
27507710
25.

Energetics of surface confined ferritin during iron loading.

Federici S, Padovani F, Poli M, Rodriguez FC, Arosio P, Depero LE, Bergese P.

Colloids Surf B Biointerfaces. 2016 Sep 1;145:520-525. doi: 10.1016/j.colsurfb.2016.05.044. Epub 2016 May 17.

PMID:
27281237
26.

Structural Ensembles of Membrane-bound α-Synuclein Reveal the Molecular Determinants of Synaptic Vesicle Affinity.

Fusco G, De Simone A, Arosio P, Vendruscolo M, Veglia G, Dobson CM.

Sci Rep. 2016 Jun 8;6:27125. doi: 10.1038/srep27125.

27.

Insights on the (Auto)Photocatalysis of Ferritin.

Saenz N, Sánchez M, Gálvez N, Carmona F, Arosio P, Dominguez-Vera JM.

Inorg Chem. 2016 Jun 20;55(12):6047-50. doi: 10.1021/acs.inorgchem.6b00547. Epub 2016 Jun 6.

PMID:
27265598
28.

Photoacoustic molecular imaging for in vivo liver iron quantitation.

Maccarinelli F, Carmona F, Regoni M, Arosio P.

J Biomed Opt. 2016 May 31;21(5):56008. doi: 10.1117/1.JBO.21.5.056008. No abstract available.

PMID:
27232595
29.

The S/T-Rich Motif in the DNAJB6 Chaperone Delays Polyglutamine Aggregation and the Onset of Disease in a Mouse Model.

Kakkar V, Månsson C, de Mattos EP, Bergink S, van der Zwaag M, van Waarde MA, Kloosterhuis NJ, Melki R, van Cruchten RT, Al-Karadaghi S, Arosio P, Dobson CM, Knowles TP, Bates GP, van Deursen JM, Linse S, van de Sluis B, Emanuelsson C, Kampinga HH.

Mol Cell. 2016 Apr 12. pii: S1097-2765(16)00227-6. doi: 10.1016/j.molcel.2016.03.017. [Epub ahead of print]

30.

Analysis of the length distribution of amyloid fibrils by centrifugal sedimentation.

Arosio P, Cedervall T, Knowles TP, Linse S.

Anal Biochem. 2016 Jul 1;504:7-13. doi: 10.1016/j.ab.2016.03.015. Epub 2016 Mar 28.

PMID:
27033008
31.

Kinetic analysis reveals the diversity of microscopic mechanisms through which molecular chaperones suppress amyloid formation.

Arosio P, Michaels TC, Linse S, Månsson C, Emanuelsson C, Presto J, Johansson J, Vendruscolo M, Dobson CM, Knowles TP.

Nat Commun. 2016 Mar 24;7:10948. doi: 10.1038/ncomms10948.

32.

Microfluidic Diffusion Viscometer for Rapid Analysis of Complex Solutions.

Arosio P, Hu K, Aprile FA, Müller T, Knowles TP.

Anal Chem. 2016 Apr 5;88(7):3488-93. doi: 10.1021/acs.analchem.5b02930. Epub 2016 Mar 16.

PMID:
26940224
33.

An anticancer drug suppresses the primary nucleation reaction that initiates the production of the toxic Aβ42 aggregates linked with Alzheimer's disease.

Habchi J, Arosio P, Perni M, Costa AR, Yagi-Utsumi M, Joshi P, Chia S, Cohen SI, Müller MB, Linse S, Nollen EA, Dobson CM, Knowles TP, Vendruscolo M.

Sci Adv. 2016 Feb 12;2(2):e1501244. doi: 10.1126/sciadv.1501244. eCollection 2016 Feb.

34.

Iron Homeostasis in Health and Disease.

Gozzelino R, Arosio P.

Int J Mol Sci. 2016 Jan 20;17(1). pii: E130. doi: 10.3390/ijms17010130. Review.

35.

Molecular mechanisms of protein aggregation from global fitting of kinetic models.

Meisl G, Kirkegaard JB, Arosio P, Michaels TC, Vendruscolo M, Dobson CM, Linse S, Knowles TP.

Nat Protoc. 2016 Feb;11(2):252-72. doi: 10.1038/nprot.2016.010. Epub 2016 Jan 7.

PMID:
26741409
36.

Microfluidic Diffusion Analysis of the Sizes and Interactions of Proteins under Native Solution Conditions.

Arosio P, Müller T, Rajah L, Yates EV, Aprile FA, Zhang Y, Cohen SI, White DA, Herling TW, De Genst EJ, Linse S, Vendruscolo M, Dobson CM, Knowles TP.

ACS Nano. 2016 Jan 26;10(1):333-41. doi: 10.1021/acsnano.5b04713. Epub 2015 Dec 23.

PMID:
26678709
37.

Characterization of magnetic nanoparticles from Magnetospirillum Gryphiswaldense as potential theranostics tools.

Orlando T, Mannucci S, Fantechi E, Conti G, Tambalo S, Busato A, Innocenti C, Ghin L, Bassi R, Arosio P, Orsini F, Sangregorio C, Corti M, Casula MF, Marzola P, Lascialfari A, Sbarbati A.

Contrast Media Mol Imaging. 2016 Mar-Apr;11(2):139-45. doi: 10.1002/cmmi.1673. Epub 2015 Nov 24.

PMID:
26598395
38.

Contribution of Electrostatics in the Fibril Stability of a Model Ionic-Complementary Peptide.

Owczarz M, Casalini T, Motta AC, Morbidelli M, Arosio P.

Biomacromolecules. 2015 Dec 14;16(12):3792-801. doi: 10.1021/acs.biomac.5b01092. Epub 2015 Nov 23.

PMID:
26594824
39.

The importance of eukaryotic ferritins in iron handling and cytoprotection.

Arosio P, Carmona F, Gozzelino R, Maccarinelli F, Poli M.

Biochem J. 2015 Nov 15;472(1):1-15. doi: 10.1042/BJ20150787. Review.

PMID:
26518749
40.

Pharmacological induction of ferritin prevents osteoblastic transformation of smooth muscle cells.

Becs G, Zarjou A, Agarwal A, Kovács KÉ, Becs Á, Nyitrai M, Balogh E, Bányai E, Eaton JW, Arosio P, Poli M, Jeney V, Balla J, Balla G.

J Cell Mol Med. 2016 Feb;20(2):217-30. doi: 10.1111/jcmm.12682. Epub 2015 Oct 26.

41.

An Intraoperative Site-specific Bone Density Device: A Pilot Test Case.

Arosio P, Moschioni M, Banfi LM, Di Stefano DA.

J Contemp Dent Pract. 2015 Aug 1;16(8):697-703.

PMID:
26423508
42.

Latent analysis of unmodified biomolecules and their complexes in solution with attomole detection sensitivity.

Yates EV, Müller T, Rajah L, De Genst EJ, Arosio P, Linse S, Vendruscolo M, Dobson CM, Knowles TP.

Nat Chem. 2015 Oct;7(10):802-9. doi: 10.1038/nchem.2344. Epub 2015 Sep 14.

PMID:
26391079
43.

Biophysical approaches for the study of interactions between molecular chaperones and protein aggregates.

Wright MA, Aprile FA, Arosio P, Vendruscolo M, Dobson CM, Knowles TP.

Chem Commun (Camb). 2015 Oct 4;51(77):14425-34. doi: 10.1039/c5cc03689e. Review.

PMID:
26328629
44.

Dynamics of protein aggregation and oligomer formation governed by secondary nucleation.

Michaels TC, Lazell HW, Arosio P, Knowles TP.

J Chem Phys. 2015 Aug 7;143(5):054901. doi: 10.1063/1.4927655.

PMID:
26254664
45.

A Colloidal Description of Intermolecular Interactions Driving Fibril-Fibril Aggregation of a Model Amphiphilic Peptide.

Owczarz M, Motta AC, Morbidelli M, Arosio P.

Langmuir. 2015 Jul 14;31(27):7590-600. doi: 10.1021/acs.langmuir.5b01110. Epub 2015 Jun 30.

PMID:
26125620
46.

Preventing peptide and protein misbehavior.

Arosio P, Meisl G, Andreasen M, Knowles TP.

Proc Natl Acad Sci U S A. 2015 Apr 28;112(17):5267-8. doi: 10.1073/pnas.1505170112. Epub 2015 Apr 20. No abstract available.

47.

A microfluidic platform for quantitative measurements of effective protein charges and single ion binding in solution.

Herling TW, Arosio P, Müller T, Linse S, Knowles TP.

Phys Chem Chem Phys. 2015 May 14;17(18):12161-7. doi: 10.1039/c5cp00746a.

PMID:
25880209
48.

Macrophage and epithelial cell H-ferritin expression regulates renal inflammation.

Bolisetty S, Zarjou A, Hull TD, Traylor AM, Perianayagam A, Joseph R, Kamal AI, Arosio P, Soares MP, Jeney V, Balla J, George JF, Agarwal A.

Kidney Int. 2015 Jul;88(1):95-108. doi: 10.1038/ki.2015.102. Epub 2015 Apr 15.

49.

A multiscale view of therapeutic protein aggregation: a colloid science perspective.

Nicoud L, Owczarz M, Arosio P, Morbidelli M.

Biotechnol J. 2015 Mar;10(3):367-78. doi: 10.1002/biot.201400858. Review.

PMID:
25772395
50.

The importance of iron in pathophysiologic conditions.

Gozzelino R, Arosio P.

Front Pharmacol. 2015 Feb 24;6:26. doi: 10.3389/fphar.2015.00026. eCollection 2015. No abstract available.

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