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Items: 7


Central-acting therapeutics alleviate respiratory weakness caused by heart failure-induced ventilatory overdrive.

Foster AJ, Platt MJ, Huber JS, Eadie AL, Arkell AM, Romanova N, Wright DC, Gillis TE, Murrant CL, Brunt KR, Simpson JA.

Sci Transl Med. 2017 May 17;9(390). pii: eaag1303. doi: 10.1126/scitranslmed.aag1303.


The Rab-GTPase activating protein, TBC1D1, is critical for maintaining normal glucose homeostasis and β-cell mass.

Paglialunga S, Simnett G, Robson H, Hoang M, Pillai R, Arkell AM, Simpson JA, Bonen A, Huising M, Joseph JW, Holloway GP.

Appl Physiol Nutr Metab. 2017 Jun;42(6):647-655. doi: 10.1139/apnm-2016-0585. Epub 2017 Jan 31.


Exercise-mediated IL-6 signaling occurs independent of inflammation and is amplified by training in mouse adipose tissue.

Castellani L, Perry CG, Macpherson RE, Root-McCaig J, Huber JS, Arkell AM, Simpson JA, Wright DC.

J Appl Physiol (1985). 2015 Dec 1;119(11):1347-54. doi: 10.1152/japplphysiol.00551.2015. Epub 2015 Oct 15.


Respiratory muscle weakness in the Zucker diabetic fatty rat.

Allwood MA, Foster AJ, Arkell AM, Beaudoin MS, Snook LA, Romanova N, Murrant CL, Holloway GP, Wright DC, Simpson JA.

Am J Physiol Regul Integr Comp Physiol. 2015 Oct;309(7):R780-7. doi: 10.1152/ajpregu.00447.2014. Epub 2015 Aug 5.


Impairments in mitochondrial palmitoyl-CoA respiratory kinetics that precede development of diabetic cardiomyopathy are prevented by resveratrol in ZDF rats.

Beaudoin MS, Perry CG, Arkell AM, Chabowski A, Simpson JA, Wright DC, Holloway GP.

J Physiol. 2014 Jun 15;592(12):2519-33. doi: 10.1113/jphysiol.2013.270538. Epub 2014 Mar 17.


Novel effects of rosiglitazone on SMAD2 and SMAD3 signaling in white adipose tissue of diabetic rats.

Beaudoin MS, Snook LA, Arkell AM, Stefanson A, Wan Z, Simpson JA, Holloway GP, Wright DC.

Obesity (Silver Spring). 2014 Jul;22(7):1632-42. doi: 10.1002/oby.20717. Epub 2014 Feb 19.


Resveratrol supplementation improves white adipose tissue function in a depot-specific manner in Zucker diabetic fatty rats.

Beaudoin MS, Snook LA, Arkell AM, Simpson JA, Holloway GP, Wright DC.

Am J Physiol Regul Integr Comp Physiol. 2013 Sep;305(5):R542-51. doi: 10.1152/ajpregu.00200.2013. Epub 2013 Jul 3.

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