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Items: 1 to 50 of 102

1.

AKT2 siRNA delivery with amphiphilic-based polymeric micelles show efficacy against cancer stem cells.

Rafael D, Gener P, Andrade F, Seras-Franzoso J, Montero S, Fernández Y, Hidalgo M, Arango D, Sayós J, Florindo HF, Abasolo I, Schwartz S Jr, Videira M.

Drug Deliv. 2018 Nov;25(1):961-972. doi: 10.1080/10717544.2018.1461276.

PMID:
29667444
2.

DUSP5 is methylated in CIMP-high colorectal cancer but is not a major regulator of intestinal cell proliferation and tumorigenesis.

Tögel L, Nightingale R, Wu R, Chüeh AC, Al-Obaidi S, Luk I, Dávalos-Salas M, Chionh F, Murone C, Buchanan DD, Chatterton Z, Sieber OM, Arango D, Tebbutt NC, Williams D, Dhillon AS, Mariadason JM.

Sci Rep. 2018 Jan 29;8(1):1767. doi: 10.1038/s41598-018-20176-9.

3.

Mechanisms of inactivation of the tumour suppressor gene RHOA in colorectal cancer.

Dopeso H, Rodrigues P, Bilic J, Bazzocco S, Cartón-García F, Macaya I, de Marcondes PG, Anguita E, Masanas M, Jiménez-Flores LM, Martínez-Barriocanal Á, Nieto R, Segura MF, Schwartz S Jr, Mariadason JM, Arango D.

Br J Cancer. 2018 Jan;118(1):106-116. doi: 10.1038/bjc.2017.420. Epub 2017 Dec 5.

PMID:
29206819
4.

Biomechanical analysis of four external fixation pin insertion techniques.

Arango D, Tiedeken N, Clippinger B, Samuel SP, Saldanha V, Shaffer G.

Orthop Rev (Pavia). 2017 Oct 3;9(3):7067. doi: 10.4081/or.2017.7067. eCollection 2017 Sep 30. Review. No abstract available.

5.

Profiling Cytidine Acetylation with Specific Affinity and Reactivity.

Sinclair WR, Arango D, Shrimp JH, Zengeya TT, Thomas JM, Montgomery DC, Fox SD, Andresson T, Oberdoerffer S, Meier JL.

ACS Chem Biol. 2017 Dec 15;12(12):2922-2926. doi: 10.1021/acschembio.7b00734. Epub 2017 Oct 17.

PMID:
29039931
6.

Acute Both Bone Fracture in a Chronic Contracted Forearm.

Ayzenberg M, Tiedeken NC, Arango DE, Raphael J.

J Orthop Case Rep. 2016 Nov-Dec;6(5):55-58. doi: 10.13107/jocr.2250-0685.630.

7.

Mortality in traffic accidents with older adults in Colombia.

Cardona AM, Arango DC, Fernández DY, Martínez AA.

Rev Saude Publica. 2017;51:21. doi: 10.1590/s1518-8787.2017051006405. Epub 2017 Mar 27. Spanish, English.

8.

Loss of the EPH receptor B6 contributes to colorectal cancer metastasis.

Mateo-Lozano S, Bazzocco S, Rodrigues P, Mazzolini R, Andretta E, Dopeso H, Fernández Y, Del Llano E, Bilic J, Suárez-López L, Macaya I, Cartón-García F, Nieto R, Jimenez-Flores LM, de Marcondes PG, Nuñez Y, Afonso E, Cacci K, Hernández-Losa J, Landolfi S, Abasolo I, Ramón Y Cajal S, Mariadason JM, Schwartz S Jr, Matsui T, Arango D.

Sci Rep. 2017 Mar 6;7:43702. doi: 10.1038/srep43702.

9.

Pullout strength of a novel hybrid fixation technique (Tape Locking Screw™) in soft-tissue ACL reconstruction: A biomechanical study in human and porcine bone.

Ayzenberg M, Arango D, Gershkovich GE, Samuel PS, Saing M.

Orthop Traumatol Surg Res. 2017 Jun;103(4):591-595. doi: 10.1016/j.otsr.2017.01.006. Epub 2017 Feb 24.

PMID:
28238964
10.

Investigation of the role of tyrosine kinase receptor EPHA3 in colorectal cancer.

Andretta E, Cartón-García F, Martínez-Barriocanal Á, de Marcondes PG, Jimenez-Flores LM, Macaya I, Bazzocco S, Bilic J, Rodrigues P, Nieto R, Landolfi S, Ramon Y Cajal S, Schwartz S, Brown A, Dopeso H, Arango D.

Sci Rep. 2017 Feb 7;7:41576. doi: 10.1038/srep41576.

11.

Dual Targeting of Bromodomain and Extraterminal Domain Proteins, and WNT or MAPK Signaling, Inhibits c-MYC Expression and Proliferation of Colorectal Cancer Cells.

Tögel L, Nightingale R, Chueh AC, Jayachandran A, Tran H, Phesse T, Wu R, Sieber OM, Arango D, Dhillon AS, Dawson MA, Diez-Dacal B, Gahman TC, Filippakopoulos P, Shiau AK, Mariadason JM.

Mol Cancer Ther. 2016 Jun;15(6):1217-26. doi: 10.1158/1535-7163.MCT-15-0724. Epub 2016 Mar 16.

12.

Dietary Apigenin Exerts Immune-Regulatory Activity in Vivo by Reducing NF-κB Activity, Halting Leukocyte Infiltration and Restoring Normal Metabolic Function.

Cardenas H, Arango D, Nicholas C, Duarte S, Nuovo GJ, He W, Voss OH, Gonzalez-Mejia ME, Guttridge DC, Grotewold E, Doseff AI.

Int J Mol Sci. 2016 Mar 1;17(3):323. doi: 10.3390/ijms17030323.

13.

Cancer stem cells and personalized cancer nanomedicine.

Gener P, Rafael DF, Fernández Y, Ortega JS, Arango D, Abasolo I, Videira M, Schwartz S Jr.

Nanomedicine (Lond). 2016 Feb;11(3):307-20. doi: 10.2217/nnm.15.200. Epub 2016 Jan 20. Review.

PMID:
26785724
14.

Bilateral Hemiarthroplasty in a Patient with Below-Knee and Above-Knee Amputations: A Case Report.

Arango D, Tiedeken NC, Gershkovich G, Shaffer G.

JBJS Case Connect. 2016 Jan-Mar;6(1):e3. doi: 10.2106/JBJS.CC.O.00114.

PMID:
29252713
15.

Fluorescent CSC models evidence that targeted nanomedicines improve treatment sensitivity of breast and colon cancer stem cells.

Gener P, Gouveia LP, Sabat GR, de Sousa Rafael DF, Fort NB, Arranja A, Fernández Y, Prieto RM, Ortega JS, Arango D, Abasolo I, Videira M, Schwartz S Jr.

Nanomedicine. 2015 Nov;11(8):1883-92. doi: 10.1016/j.nano.2015.07.009. Epub 2015 Jul 31.

PMID:
26238079
16.

Myo5b knockout mice as a model of microvillus inclusion disease.

Cartón-García F, Overeem AW, Nieto R, Bazzocco S, Dopeso H, Macaya I, Bilic J, Landolfi S, Hernandez-Losa J, Schwartz S Jr, Ramon y Cajal S, van Ijzendoorn SC, Arango D.

Sci Rep. 2015 Jul 23;5:12312. doi: 10.1038/srep12312.

17.

The intestinal epithelial cell differentiation marker intestinal alkaline phosphatase (ALPi) is selectively induced by histone deacetylase inhibitors (HDACi) in colon cancer cells in a Kruppel-like factor 5 (KLF5)-dependent manner.

Shin J, Carr A, Corner GA, Tögel L, Dávalos-Salas M, Tran H, Chueh AC, Al-Obaidi S, Chionh F, Ahmed N, Buchanan DD, Young JP, Malo MS, Hodin RA, Arango D, Sieber OM, Augenlicht LH, Dhillon AS, Weber TK, Mariadason JM.

J Biol Chem. 2015 Jun 19;290(25):15392. doi: 10.1074/jbc.A114.557546. No abstract available.

18.

Highly Expressed Genes in Rapidly Proliferating Tumor Cells as New Targets for Colorectal Cancer Treatment.

Bazzocco S, Dopeso H, Carton-Garcia F, Macaya I, Andretta E, Chionh F, Rodrigues P, Garrido M, Alazzouzi H, Nieto R, Sanchez A, Schwartz S Jr, Bilic J, Mariadason JM, Arango D.

Clin Cancer Res. 2015 Aug 15;21(16):3695-704. doi: 10.1158/1078-0432.CCR-14-2457. Epub 2015 May 5.

19.

PTPRD is homozygously deleted and epigenetically downregulated in human hepatocellular carcinomas.

Acun T, Demir K, Oztas E, Arango D, Yakicier MC.

OMICS. 2015 Apr;19(4):220-9. doi: 10.1089/omi.2015.0010.

PMID:
25831062
20.

Dietary apigenin reduces LPS-induced expression of miR-155 restoring immune balance during inflammation.

Arango D, Diosa-Toro M, Rojas-Hernandez LS, Cooperstone JL, Schwartz SJ, Mo X, Jiang J, Schmittgen TD, Doseff AI.

Mol Nutr Food Res. 2015 Apr;59(4):763-72. doi: 10.1002/mnfr.201400705. Epub 2015 Feb 23.

PMID:
25641956
21.

Prevention of violence against women and girls: what does the evidence say?

Ellsberg M, Arango DJ, Morton M, Gennari F, Kiplesund S, Contreras M, Watts C.

Lancet. 2015 Apr 18;385(9977):1555-66. doi: 10.1016/S0140-6736(14)61703-7. Epub 2014 Nov 21. Review.

PMID:
25467575
22.

RHOA inactivation enhances Wnt signalling and promotes colorectal cancer.

Rodrigues P, Macaya I, Bazzocco S, Mazzolini R, Andretta E, Dopeso H, Mateo-Lozano S, Bilić J, Cartón-García F, Nieto R, Suárez-López L, Afonso E, Landolfi S, Hernandez-Losa J, Kobayashi K, Ramón y Cajal S, Tabernero J, Tebbutt NC, Mariadason JM, Schwartz S Jr, Arango D.

Nat Commun. 2014 Nov 21;5:5458. doi: 10.1038/ncomms6458.

23.

The intestinal epithelial cell differentiation marker intestinal alkaline phosphatase (ALPi) is selectively induced by histone deacetylase inhibitors (HDACi) in colon cancer cells in a Kruppel-like factor 5 (KLF5)-dependent manner.

Shin J, Carr A, Corner GA, Tögel L, Dávalos-Salas M, Tran H, Chueh AC, Al-Obaidi S, Chionh F, Ahmed N, Buchanan DD, Young JP, Malo MS, Hodin RA, Arango D, Sieber OM, Augenlicht LH, Dhillon AS, Weber TK, Mariadason JM.

J Biol Chem. 2014 Sep 5;289(36):25306-16. doi: 10.1074/jbc.M114.557546. Epub 2014 Jul 18. Erratum in: J Biol Chem. 2015 Jun 19;290(25):15392. Dávaos-Salas, Mercedes [Corrected to Dávalos-Salas, Mercedes].

24.

Open perilunate injury with lunate revascularization after complete ligamentous avulsion.

Arango D, Tiedeken NC, Ayzenberg M, Raphael J.

J Surg Case Rep. 2014 May 12;2014(5). pii: rju041. doi: 10.1093/jscr/rju041.

25.

Colorectal cancer cell lines are representative models of the main molecular subtypes of primary cancer.

Mouradov D, Sloggett C, Jorissen RN, Love CG, Li S, Burgess AW, Arango D, Strausberg RL, Buchanan D, Wormald S, O'Connor L, Wilding JL, Bicknell D, Tomlinson IP, Bodmer WF, Mariadason JM, Sieber OM.

Cancer Res. 2014 Jun 15;74(12):3238-47. doi: 10.1158/0008-5472.CAN-14-0013. Epub 2014 Apr 22.

26.

Apigenin protects endothelial cells from lipopolysaccharide (LPS)-induced inflammation by decreasing caspase-3 activation and modulating mitochondrial function.

Duarte S, Arango D, Parihar A, Hamel P, Yasmeen R, Doseff AI.

Int J Mol Sci. 2013 Aug 28;14(9):17664-79. doi: 10.3390/ijms140917664.

27.

National access to care for children with fractures.

Iobst C, Arango D, Segal D, Skaggs DL.

J Pediatr Orthop. 2013 Sep;33(6):587-91. doi: 10.1097/BPO.0b013e31829b2da4.

PMID:
23812144
28.

Molecular basis for the action of a dietary flavonoid revealed by the comprehensive identification of apigenin human targets.

Arango D, Morohashi K, Yilmaz A, Kuramochi K, Parihar A, Brahimaj B, Grotewold E, Doseff AI.

Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):E2153-62. doi: 10.1073/pnas.1303726110. Epub 2013 May 22.

29.

Two-year outcome with the AperFix system for ACL reconstruction.

Uribe JW, Arango D, Frank J, Kiebzak GM.

Orthopedics. 2013 Feb;36(2):e159-64. doi: 10.3928/01477447-20130122-17.

PMID:
23379927
30.

Selected anatomists: at the boundary of contemporary ethics.

Arango D, Greiffenstein P, O'Leary JP.

JAMA Surg. 2013 Jan;148(1):94-8. doi: 10.1001/jamasurgery.2013.407.

PMID:
23324845
31.

Human SMC2 protein, a core subunit of human condensin complex, is a novel transcriptional target of the WNT signaling pathway and a new therapeutic target.

Dávalos V, Súarez-López L, Castaño J, Messent A, Abasolo I, Fernandez Y, Guerra-Moreno A, Espín E, Armengol M, Musulen E, Ariza A, Sayós J, Arango D, Schwartz S Jr.

J Biol Chem. 2012 Dec 21;287(52):43472-81. doi: 10.1074/jbc.M112.428466. Epub 2012 Oct 24.

32.

Brush border myosin Ia inactivation in gastric but not endometrial tumors.

Mazzolini R, Rodrigues P, Bazzocco S, Dopeso H, Ferreira AM, Mateo-Lozano S, Andretta E, Woerner SM, Alazzouzi H, Landolfi S, Hernandez-Losa J, Macaya I, Suzuki H, Ramón y Cajal S, Mooseker MS, Mariadason JM, Gebert J, Hofstra RM, Reventós J, Yamamoto H, Schwartz S Jr, Arango D.

Int J Cancer. 2013 Apr 15;132(8):1790-9. doi: 10.1002/ijc.27856. Epub 2012 Oct 20.

33.

Apigenin induces DNA damage through the PKCδ-dependent activation of ATM and H2AX causing down-regulation of genes involved in cell cycle control and DNA repair.

Arango D, Parihar A, Villamena FA, Wang L, Freitas MA, Grotewold E, Doseff AI.

Biochem Pharmacol. 2012 Dec 15;84(12):1571-80. doi: 10.1016/j.bcp.2012.09.005. Epub 2012 Sep 14.

34.

High-throughput screening of transglutaminase activity using plasmonic fluorescent nanocomposites.

Achyuthan KE, Allen A, Arango DC, Harper JC, Brozik SM.

Anal Sci. 2012;28(9):905-10.

35.

Rational redesign of glucose oxidase for improved catalytic function and stability.

Holland JT, Harper JC, Dolan PL, Manginell MM, Arango DC, Rawlings JA, Apblett CA, Brozik SM.

PLoS One. 2012;7(6):e37924. doi: 10.1371/journal.pone.0037924. Epub 2012 Jun 13.

36.

Flavone deglycosylation increases their anti-inflammatory activity and absorption.

Hostetler G, Riedl K, Cardenas H, Diosa-Toro M, Arango D, Schwartz S, Doseff AI.

Mol Nutr Food Res. 2012 Apr;56(4):558-69. doi: 10.1002/mnfr.201100596. Epub 2012 Feb 20.

37.

Villin expression is frequently lost in poorly differentiated colon cancer.

Arango D, Al-Obaidi S, Williams DS, Dopeso H, Mazzolini R, Corner G, Byun DS, Carr AA, Murone C, Tögel L, Zeps N, Aaltonen LA, Iacopetta B, Mariadason JM.

Am J Pathol. 2012 Apr;180(4):1509-21. doi: 10.1016/j.ajpath.2012.01.006. Epub 2012 Feb 18.

38.

Brush border myosin Ia has tumor suppressor activity in the intestine.

Mazzolini R, Dopeso H, Mateo-Lozano S, Chang W, Rodrigues P, Bazzocco S, Alazzouzi H, Landolfi S, Hernández-Losa J, Andretta E, Alhopuro P, Espín E, Armengol M, Tabernero J, Ramón y Cajal S, Kloor M, Gebert J, Mariadason JM, Schwartz S Jr, Aaltonen LA, Mooseker MS, Arango D.

Proc Natl Acad Sci U S A. 2012 Jan 31;109(5):1530-5. doi: 10.1073/pnas.1108411109. Epub 2012 Jan 18.

39.

Multiplexed microneedle-based biosensor array for characterization of metabolic acidosis.

Miller PR, Skoog SA, Edwards TL, Lopez DM, Wheeler DR, Arango DC, Xiao X, Brozik SM, Wang J, Polsky R, Narayan RJ.

Talanta. 2012 Jan 15;88:739-42. doi: 10.1016/j.talanta.2011.11.046. Epub 2011 Nov 22.

40.

Endovascular repair of infrarenal aortic aneurysms in octogenarians and nonagenarians.

Geisbüsch P, Katzen BT, Tsoukas AI, Arango D, Peña CS, Benenati JF.

J Vasc Surg. 2011 Dec;54(6):1605-13. doi: 10.1016/j.jvs.2011.06.096. Epub 2011 Sep 9.

41.

Candidate driver genes in microsatellite-unstable colorectal cancer.

Alhopuro P, Sammalkorpi H, Niittymäki I, Biström M, Raitila A, Saharinen J, Nousiainen K, Lehtonen HJ, Heliövaara E, Puhakka J, Tuupanen S, Sousa S, Seruca R, Ferreira AM, Hofstra RM, Mecklin JP, Järvinen H, Ristimäki A, Orntoft TF, Hautaniemi S, Arango D, Karhu A, Aaltonen LA.

Int J Cancer. 2012 Apr 1;130(7):1558-66. doi: 10.1002/ijc.26167. Epub 2011 Aug 3.

42.

Mutations in the circadian gene CLOCK in colorectal cancer.

Alhopuro P, Björklund M, Sammalkorpi H, Turunen M, Tuupanen S, Biström M, Niittymäki I, Lehtonen HJ, Kivioja T, Launonen V, Saharinen J, Nousiainen K, Hautaniemi S, Nuorva K, Mecklin JP, Järvinen H, Orntoft T, Arango D, Lehtonen R, Karhu A, Taipale J, Aaltonen LA.

Mol Cancer Res. 2010 Jul;8(7):952-60. doi: 10.1158/1541-7786.MCR-10-0086. Epub 2010 Jun 15.

43.

[Population dynamics of the palm Euterpe oleracea (Arecaceae) from flooded forests in Choco, Colombian Pacific].

Arango DA, Duque AJ, Muñoz E.

Rev Biol Trop. 2010 Mar;58(1):465-81. Spanish.

PMID:
20411735
44.

Aprataxin tumor levels predict response of colorectal cancer patients to irinotecan-based treatment.

Dopeso H, Mateo-Lozano S, Elez E, Landolfi S, Ramos Pascual FJ, Hernández-Losa J, Mazzolini R, Rodrigues P, Bazzocco S, Carreras MJ, Espín E, Armengol M, Wilson AJ, Mariadason JM, Ramon Y Cajal S, Tabernero J, Schwartz S Jr, Arango D.

Clin Cancer Res. 2010 Apr 15;16(8):2375-82. doi: 10.1158/1078-0432.CCR-09-3275. Epub 2010 Apr 6.

45.

Apoptotic sensitivity of colon cancer cells to histone deacetylase inhibitors is mediated by an Sp1/Sp3-activated transcriptional program involving immediate-early gene induction.

Wilson AJ, Chueh AC, Tögel L, Corner GA, Ahmed N, Goel S, Byun DS, Nasser S, Houston MA, Jhawer M, Smartt HJ, Murray LB, Nicholas C, Heerdt BG, Arango D, Augenlicht LH, Mariadason JM.

Cancer Res. 2010 Jan 15;70(2):609-20. doi: 10.1158/0008-5472.CAN-09-2327. Epub 2010 Jan 12.

46.

Metastasis-Associated Gene Expression Changes Predict Poor Outcomes in Patients with Dukes Stage B and C Colorectal Cancer.

Jorissen RN, Gibbs P, Christie M, Prakash S, Lipton L, Desai J, Kerr D, Aaltonen LA, Arango D, Kruhøffer M, Orntoft TF, Andersen CL, Gruidl M, Kamath VP, Eschrich S, Yeatman TJ, Sieber OM.

Clin Cancer Res. 2009 Dec 15;15(24):7642-7651.

47.

An A13 repeat within the 3'-untranslated region of epidermal growth factor receptor (EGFR) is frequently mutated in microsatellite instability colon cancers and is associated with increased EGFR expression.

Yuan Z, Shin J, Wilson A, Goel S, Ling YH, Ahmed N, Dopeso H, Jhawer M, Nasser S, Montagna C, Fordyce K, Augenlicht LH, Aaltonen LA, Arango D, Weber TK, Mariadason JM.

Cancer Res. 2009 Oct 1;69(19):7811-8. doi: 10.1158/0008-5472.CAN-09-0986. Epub 2009 Sep 29. Erratum in: Cancer Res. 2010 Feb 1;70(3):1275.

48.

The receptor tyrosine kinase EPHB4 has tumor suppressor activities in intestinal tumorigenesis.

Dopeso H, Mateo-Lozano S, Mazzolini R, Rodrigues P, Lagares-Tena L, Ceron J, Romero J, Esteves M, Landolfi S, Hernández-Losa J, Castaño J, Wilson AJ, Ramon y Cajal S, Mariadason JM, Schwartz S Jr, Arango D.

Cancer Res. 2009 Sep 15;69(18):7430-8. doi: 10.1158/0008-5472.CAN-09-0706. Epub 2009 Sep 8.

49.

Antimicrobial peptide interactions with silica bead supported bilayers and E. coli: buforin II, magainin II, and arenicin.

Davis RW, Arango DC, Jones HD, Van Benthem MH, Haaland DM, Brozik SM, Sinclair MB.

J Pept Sci. 2009 Aug;15(8):511-22. doi: 10.1002/psc.1152.

PMID:
19591202
50.

A multifunctional thin film Au electrode surface formed by consecutive electrochemical reduction of aryl diazonium salts.

Harper JC, Polsky R, Wheeler DR, Lopez DM, Arango DC, Brozik SM.

Langmuir. 2009 Mar 3;25(5):3282-8. doi: 10.1021/la803215z.

PMID:
19437729

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