Sort by
Items per page

Send to

Choose Destination

Search results

Items: 17


Blood Pressure in Acute Stroke: To Treat or Not to Treat: That Is Still the Question.

Bath PM, Appleton JP, Krishnan K, Sprigg N.

Stroke. 2018 Jun 12. pii: STROKEAHA.118.021254. doi: 10.1161/STROKEAHA.118.021254. [Epub ahead of print] Review. No abstract available.


Tranexamic acid for hyperacute primary IntraCerebral Haemorrhage (TICH-2): an international randomised, placebo-controlled, phase 3 superiority trial.

Sprigg N, Flaherty K, Appleton JP, Salman RA, Bereczki D, Beridze M, Christensen H, Ciccone A, Collins R, Czlonkowska A, Dineen RA, Duley L, Egea-Guerrero JJ, England TJ, Krishnan K, Laska AC, Law ZK, Ozturk S, Pocock SJ, Roberts I, Robinson TG, Roffe C, Seiffge D, Scutt P, Thanabalan J, Werring D, Whynes D, Bath PM; TICH-2 Investigators.

Lancet. 2018 May 26;391(10135):2107-2115. doi: 10.1016/S0140-6736(18)31033-X. Epub 2018 May 16.


Antiplatelet therapy with aspirin, clopidogrel, and dipyridamole versus clopidogrel alone or aspirin and dipyridamole in patients with acute cerebral ischaemia (TARDIS): a randomised, open-label, phase 3 superiority trial.

Bath PM, Woodhouse LJ, Appleton JP, Beridze M, Christensen H, Dineen RA, Duley L, England TJ, Flaherty K, Havard D, Heptinstall S, James M, Krishnan K, Markus HS, Montgomery AA, Pocock SJ, Randall M, Ranta A, Robinson TG, Scutt P, Venables GS, Sprigg N; TARDIS Investigators.

Lancet. 2018 Mar 3;391(10123):850-859. doi: 10.1016/S0140-6736(17)32849-0. Epub 2017 Dec 20.


Assessment of consent models as an ethical consideration in the conduct of prehospital ambulance randomised controlled clinical trials: a systematic review.

Armstrong S, Langlois A, Laparidou D, Dixon M, Appleton JP, Bath PM, Snooks H, Siriwardena AN.

BMC Med Res Methodol. 2017 Sep 16;17(1):142. doi: 10.1186/s12874-017-0423-4.


Preventing cognitive decline and dementia from cerebral small vessel disease: The LACI-1 Trial. Protocol and statistical analysis plan of a phase IIa dose escalation trial testing tolerability, safety and effect on intermediary endpoints of isosorbide mononitrate and cilostazol, separately and in combination.

Blair GW, Appleton JP, Law ZK, Doubal F, Flaherty K, Dooley R, Shuler K, Richardson C, Hamilton I, Shi Y, Stringer M, Boyd J, Thrippleton MJ, Sprigg N, Bath PM, Wardlaw JM.

Int J Stroke. 2018 Jul;13(5):530-538. doi: 10.1177/1747493017731947. Epub 2017 Sep 14.


Ambulance-delivered transdermal glyceryl trinitrate versus sham for ultra-acute stroke: Rationale, design and protocol for the Rapid Intervention with Glyceryl trinitrate in Hypertensive stroke Trial-2 (RIGHT-2) trial (ISRCTN26986053).

Appleton JP, Scutt P, Dixon M, Howard H, Haywood L, Havard D, Hepburn T, England T, Sprigg N, Woodhouse LJ, Wardlaw JM, Montgomery AA, Pocock S, Bath PM; RIGHT-2 Investigators.

Int J Stroke. 2017 Jan 1:1747493017724627. doi: 10.1177/1747493017724627. [Epub ahead of print]


Hypercholesterolaemia and vascular dementia.

Appleton JP, Scutt P, Sprigg N, Bath PM.

Clin Sci (Lond). 2017 Jun 30;131(14):1561-1578. doi: 10.1042/CS20160382. Print 2017 Jul 15. Review.


Nitric oxide donors (nitrates), L-arginine, or nitric oxide synthase inhibitors for acute stroke.

Bath PM, Krishnan K, Appleton JP.

Cochrane Database Syst Rev. 2017 Apr 21;4:CD000398. doi: 10.1002/14651858.CD000398.pub2. Review.


Management of acute intracerebral haemorrhage - an update.

Law ZK, Appleton JP, Bath PM, Sprigg N.

Clin Med (Lond). 2017 Apr;17(2):166-172. doi: 10.7861/clinmedicine.17-2-166.


Therapeutic Potential of Transdermal Glyceryl Trinitrate in the Management of Acute Stroke.

Appleton JP, Sprigg N, Bath PM.

CNS Drugs. 2017 Jan;31(1):1-9. doi: 10.1007/s40263-016-0387-7. Review.


Baseline characteristics of the 3096 patients recruited into the 'Triple Antiplatelets for Reducing Dependency after Ischemic Stroke' trial.

Bath PM, Appleton JP, Beridze M, Christensen H, Dineen RA, Duley L, England TJ, Heptinstall S, James M, Krishnan K, Markus HS, Pocock S, Ranta A, Robinson TG, Flaherty K, Scutt P, Venables GS, Woodhouse LJ, Sprigg N.

Int J Stroke. 2017 Jul;12(5):524-538. doi: 10.1177/1747493016677988. Epub 2016 Nov 4.


The Insulin Resistance Intervention after Stroke trial: A perspective on future practice and research.

Bath PM, Appleton JP, Sprigg N.

Int J Stroke. 2016 Oct;11(7):741-3. doi: 10.1177/1747493016660099. Epub 2016 Jul 12.


Blood pressure management in acute stroke.

Appleton JP, Sprigg N, Bath PM.

Stroke Vasc Neurol. 2016 Jun 24;1(2):72-82. doi: 10.1136/svn-2016-000020. eCollection 2016 Jun. Review.


Improving the likelihood of neurology patients being examined using patient feedback.

Appleton JP, Ilinca A, Lindgren A, Puschmann A, Hbahbih M, A Siddiqui K, de Silva R, Jones M, Butterworth R, Willmot M, Hayton T, Lunn M, Nicholl D.

BMJ Qual Improv Rep. 2015 Nov 5;4(1). pii: u209610.w4063. doi: 10.1136/bmjquality.u209610.w4063. eCollection 2015.


Comment on: 'Direct ophthalmoscopy should be taught to undergraduate medical students'.

Appleton JP, Nicholl DJ.

Eye (Lond). 2016 Feb;30(2):327. doi: 10.1038/eye.2015.226. Epub 2015 Nov 27. No abstract available.


Clinical neurology: why this still matters in the 21st century.

Nicholl DJ, Appleton JP.

J Neurol Neurosurg Psychiatry. 2015 Feb;86(2):229-33. doi: 10.1136/jnnp-2013-306881. Epub 2014 May 29. Review.


Myeloma crystal tubulopathy and Fanconi syndrome: a rare histological finding.

Appleton JP, Day C, Neil D, Wandroo FA.

Br J Haematol. 2012 Jul;158(1):1. doi: 10.1111/j.1365-2141.2012.09172.x. Epub 2012 May 21. No abstract available.


Supplemental Content

Loading ...
Support Center