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Fostering the Career Development of Future Educational Leaders: The Success of the Association of Pediatric Program Directors Leadership in Educational Academic Development Program.

Haftel HM, Swan R, Anderson MS, Caputo GL, Frohna JG, Li ST, Shugerman RP, Trimm F, Vinci RJ, Waggoner-Fountain LA, Bostwick SB.

J Pediatr. 2018 Mar;194:5-6.e1. doi: 10.1016/j.jpeds.2017.11.066. No abstract available.


Infliximab Plus Intravenous Immunoglobulin (IVIG) Versus IVIG Alone as Initial Therapy in Children with Kawasaki Disease Presenting with Coronary Artery Lesions: Is Dual Therapy More Effective?

Jone PN, Anderson MS, Mulvahill MJ, Heizer H, Glodé MP, Dominguez SR.

Pediatr Infect Dis J. 2018 Feb 15. doi: 10.1097/INF.0000000000001951. [Epub ahead of print]


Age-Associated Decline in Thymic B Cell Expression of Aire and Aire-Dependent Self-Antigens.

Cepeda S, Cantu C, Orozco S, Xiao Y, Brown Z, Semwal MK, Venables T, Anderson MS, Griffith AV.

Cell Rep. 2018 Jan 30;22(5):1276-1287. doi: 10.1016/j.celrep.2018.01.015.


Genome Sequences of Four Subcluster L2 Mycobacterium Phages, Finemlucis, Miley16, Wilder, and Zakai.

Herren CD, Peister A, Breton TS, Hill MS, Anderson MS, Chang AW, Klein SB, Thornton MM, Vars SJ, Wagner KE, Wiebe PL, Williams TG, Yanez CP, Ackles JM, Artis D, Brazier RJ, Bryant RJ, Callwood KO, Carter IH, DeBose CL, Edwards CD, Ezemba IC, Joaquin RR, Meghoo-Peddie ZM, Meghoo-Peddie ZG, Moore RW, Smith CE, Turner AJ, Vorters RL, Wider JJ, Krout LL, Comis MS, Davick MJ, Michaud EE, Shevenell BE, Stanley SE, Frank CI, Montgomery JR, Blumer LS, Doty JA, Smith-Caldas M, Pope WH, Cresawn SG, Russell DA, Garlena RA, Jacobs-Sera D, Hatfull GF.

Genome Announc. 2017 Nov 16;5(46). pii: e01233-17. doi: 10.1128/genomeA.01233-17.


Dominant-negative loss of function arises from a second, more frequent variant within the SAND domain of autoimmune regulator (AIRE).

Abbott JK, Huoh YS, Reynolds PR, Yu L, Rewers M, Reddy M, Anderson MS, Hur S, Gelfand EW.

J Autoimmun. 2018 Mar;88:114-120. doi: 10.1016/j.jaut.2017.10.010. Epub 2017 Nov 10.


Insights into immune tolerance from AIRE deficiency.

Proekt I, Miller CN, Lionakis MS, Anderson MS.

Curr Opin Immunol. 2017 Dec;49:71-78. doi: 10.1016/j.coi.2017.10.003. Epub 2017 Oct 21. Review.


Revisiting the Road Map of Medullary Thymic Epithelial Cell Differentiation.

Michel C, Miller CN, Küchler R, Brors B, Anderson MS, Kyewski B, Pinto S.

J Immunol. 2017 Nov 15;199(10):3488-3503. doi: 10.4049/jimmunol.1700203. Epub 2017 Oct 9.


Erratum to: Understanding and preventing type 1 diabetes through the unique working model of TrialNet.

Battaglia M, Anderson MS, Buckner JH, Geyer SM, Gottlieb PA, Kay TWH, Lernmark Å, Muller S, Pugliese A, Roep BO, Greenbaum CJ, Peakman M.

Diabetologia. 2017 Dec;60(12):2540. doi: 10.1007/s00125-017-4446-5. No abstract available.


Combination central tolerance and peripheral checkpoint blockade unleashes antimelanoma immunity.

Bakhru P, Zhu ML, Wang HH, Hong LK, Khan I, Mouchess M, Gulati AS, Starmer J, Hou Y, Sailer D, Lee S, Zhao F, Kirkwood JM, Moschos S, Fong L, Anderson MS, Su MA.

JCI Insight. 2017 Sep 21;2(18). pii: 93265. doi: 10.1172/jci.insight.93265. [Epub ahead of print]


Biochemical and aerosol characterization of ricin for use in non-clinical efficacy studies.

Barnewall RE, Riffle CG, Jones RL, Guistino DJ, Chou RM, Anderson MS, Vassar ML, Howland CA.

J Biochem Mol Toxicol. 2017 Dec;31(12). doi: 10.1002/jbt.21980. Epub 2017 Sep 7.


Discovery of stimulation-responsive immune enhancers with CRISPR activation.

Simeonov DR, Gowen BG, Boontanrart M, Roth TL, Gagnon JD, Mumbach MR, Satpathy AT, Lee Y, Bray NL, Chan AY, Lituiev DS, Nguyen ML, Gate RE, Subramaniam M, Li Z, Woo JM, Mitros T, Ray GJ, Curie GL, Naddaf N, Chu JS, Ma H, Boyer E, Van Gool F, Huang H, Liu R, Tobin VR, Schumann K, Daly MJ, Farh KK, Ansel KM, Ye CJ, Greenleaf WJ, Anderson MS, Bluestone JA, Chang HY, Corn JE, Marson A.

Nature. 2017 Sep 7;549(7670):111-115. doi: 10.1038/nature23875. Epub 2017 Aug 30.


Single-Dose and Multiple-Dose Pharmacokinetics of Vaniprevir in Healthy Men.

Caro L, de Hoon J, Depré M, Cilissen C, Miller J, Gao W, Panebianco D, Guo Z, Troemel SL, Anderson MS, Uemura N, Butterton J, Wagner J, Wright DH.

Clin Transl Sci. 2017 Nov;10(6):480-486. doi: 10.1111/cts.12482. Epub 2017 Aug 10.


The Fluorocycline TP-271 Is Efficacious in Models of Aerosolized Bacillus anthracis Infection in BALB/c Mice and Cynomolgus Macaques.

Grossman TH, Anderson MS, Drabek L, Gooldy M, Heine HS, Henning LN, Lin W, Newman JV, Nevarez R, Siefkas-Patterson K, Radcliff AK, Sutcliffe JA.

Antimicrob Agents Chemother. 2017 Sep 22;61(10). pii: e01103-17. doi: 10.1128/AAC.01103-17. Print 2017 Oct.


Understanding and preventing type 1 diabetes through the unique working model of TrialNet.

Battaglia M, Anderson MS, Buckner JH, Geyer SM, Gottlieb PA, Kay TWH, Lernmark Å, Muller S, Pugliese A, Roep BO, Greenbaum CJ, Peakman M.

Diabetologia. 2017 Nov;60(11):2139-2147. doi: 10.1007/s00125-017-4384-2. Epub 2017 Aug 2. Review. Erratum in: Diabetologia. 2017 Sep 26;:.


Spotlight on brimonidine topical gel 0.33% for facial erythema of rosacea: safety, efficacy, and patient acceptability.

Anderson MS, Nadkarni A, Cardwell LA, Alinia H, Feldman SR.

Patient Prefer Adherence. 2017 Jul 6;11:1143-1150. doi: 10.2147/PPA.S115708. eCollection 2017. Review.


The Fluorocycline TP-271 Is Efficacious in Models of Aerosolized Francisella tularensis SCHU S4 Infection in BALB/c Mice and Cynomolgus Macaques.

Grossman TH, Anderson MS, Christ D, Gooldy M, Henning LN, Heine HS, Kindt MV, Lin W, Siefkas-Patterson K, Radcliff AK, Tam VH, Sutcliffe JA.

Antimicrob Agents Chemother. 2017 Jul 25;61(8). pii: e00448-17. doi: 10.1128/AAC.00448-17. Print 2017 Aug.


Outcomes After Distal Radius Fracture Treatment With Percutaneous Wire Versus Plate Fixation: Meta-Analysis of Randomized Controlled Trials.

Anderson MS, Ghamsary M, Guillen PT, Wongworawat MD.

J Surg Orthop Adv. 2017 Spring;26(1):7-17.


No Pharmacokinetic Drug-Drug Interaction Between Prasugrel and Vorapaxar Following Multiple-Dose Administration in Healthy Volunteers.

Anderson MS, Kosoglou T, Statkevich P, Li J, Rotonda J, Meehan AG, Cutler DL.

Clin Pharmacol Drug Dev. 2018 Feb;7(2):143-150. doi: 10.1002/cpdd.354. Epub 2017 Apr 12.


The Effect of Single and Multiple Doses of Rifampin on the Pharmacokinetics of Doravirine in Healthy Subjects.

Yee KL, Khalilieh SG, Sanchez RI, Liu R, Anderson MS, Manthos H, Judge T, Brejda J, Butterton JR.

Clin Drug Investig. 2017 Jul;37(7):659-667. doi: 10.1007/s40261-017-0513-4.


Exome Sequencing Reveals Mutations in AIRE as a Cause of Isolated Hypoparathyroidism.

Li D, Streeten EA, Chan A, Lwin W, Tian L, Pellegrino da Silva R, Kim CE, Anderson MS, Hakonarson H, Levine MA.

J Clin Endocrinol Metab. 2017 May 1;102(5):1726-1733. doi: 10.1210/jc.2016-3836.


Risk versus benefit or risk versus risk: Risk aversion in the medical decision making process.

Oussedik E, Anderson MS, Feldman SR.

J Dermatolog Treat. 2017 Feb;28(1):1-2. doi: 10.1080/09546634.2017.1290575. No abstract available.


Erratum to: A Two-Way Steady-State Pharmacokinetic Interaction Study of Doravirine (MK-1439) and Dolutegravir.

Anderson MS, Khalilieh S, Yee KL, Liu R, Fan L, Rizk ML, Shah V, Hussaini A, Song I, Ross LL, Butterton JR.

Clin Pharmacokinet. 2017 Jun;56(6):679-681. doi: 10.1007/s40262-017-0517-5. No abstract available.


The influence of genetic predisposition and autoimmune hepatitis inducing antigens in disease development.

Hardtke-Wolenski M, Dywicki J, Fischer K, Hapke M, Sievers M, Schlue J, Anderson MS, Taubert R, Noyan F, Manns MP, Jaeckel E.

J Autoimmun. 2017 Mar;78:39-45. doi: 10.1016/j.jaut.2016.12.001. Epub 2016 Dec 11.


Tolerance checkpoint bypass permits emergence of pathogenic T cells to neuromyelitis optica autoantigen aquaporin-4.

Sagan SA, Winger RC, Cruz-Herranz A, Nelson PA, Hagberg S, Miller CN, Spencer CM, Ho PP, Bennett JL, Levy M, Levin MH, Verkman AS, Steinman L, Green AJ, Anderson MS, Sobel RA, Zamvil SS.

Proc Natl Acad Sci U S A. 2016 Dec 20;113(51):14781-14786. doi: 10.1073/pnas.1617859114. Epub 2016 Dec 8.


A Two-Way Steady-State Pharmacokinetic Interaction Study of Doravirine (MK-1439) and Dolutegravir.

Anderson MS, Khalilieh S, Yee KL, Liu R, Fan L, Rizk ML, Shah V, Hussaini A, Song I, Ross LL, Butterton JR.

Clin Pharmacokinet. 2017 Jun;56(6):661-669. doi: 10.1007/s40262-016-0458-4. Erratum in: Clin Pharmacokinet. 2017 Jun;56(6):679-681.


LYN- and AIRE-mediated tolerance checkpoint defects synergize to trigger organ-specific autoimmunity.

Proekt I, Miller CN, Jeanne M, Fasano KJ, Moon JJ, Lowell CA, Gould DB, Anderson MS, DeFranco AL.

J Clin Invest. 2016 Oct 3;126(10):3758-3771. doi: 10.1172/JCI84440. Epub 2016 Aug 29.


Kawasaki Disease and Exposure to Fine Particulate Air Pollution.

Zeft AS, Burns JC, Yeung RS, McCrindle BW, Newburger JW, Dominguez SR, Anderson MS, Arrington C, Shulman ST, Yoon J, Tewelde H, Mix C, Pope CA.

J Pediatr. 2016 Oct;177:179-183.e1. doi: 10.1016/j.jpeds.2016.06.061. Epub 2016 Aug 2.


Effect of Vorapaxar Alone and in Combination with Aspirin on Bleeding Time and Platelet Aggregation in Healthy Adult Subjects.

Kraft WK, Gilmartin JH, Chappell DL, Gheyas F, Walker BM, Nagalla S, Naik UP, Horrow JC, Wrishko RE, Zhang S, Anderson MS.

Clin Transl Sci. 2016 Aug;9(4):221-7. doi: 10.1111/cts.12405. Epub 2016 Jun 15.


Myocardial Strain and Strain Rate in Kawasaki Disease: Range, Recovery, and Relationship to Systemic Inflammation/Coronary Artery Dilation.

Frank B, Davidson J, Tong S, Martin B, Heizer H, Anderson MS, Glode MP, Dominguez SR, Jone PN.

J Clin Exp Cardiolog. 2016 Apr;7(4). pii: 432. Epub 2016 Apr 21.


Autoantibodies Targeting a Collecting Duct-Specific Water Channel in Tubulointerstitial Nephritis.

Landegren N, Pourmousa Lindberg M, Skov J, Hallgren Å, Eriksson D, Lisberg Toft-Bertelsen T, MacAulay N, Hagforsen E, Räisänen-Sokolowski A, Saha H, Nilsson T, Nordmark G, Ohlsson S, Gustafsson J, Husebye ES, Larsson E, Anderson MS, Perheentupa J, Rorsman F, Fenton RA, Kämpe O.

J Am Soc Nephrol. 2016 Oct;27(10):3220-3228. Epub 2016 Mar 16.


AIRE expands: new roles in immune tolerance and beyond.

Anderson MS, Su MA.

Nat Rev Immunol. 2016 Apr;16(4):247-58. doi: 10.1038/nri.2016.9. Epub 2016 Mar 14. Review.


Proteome-wide survey of the autoimmune target repertoire in autoimmune polyendocrine syndrome type 1.

Landegren N, Sharon D, Freyhult E, Hallgren Å, Eriksson D, Edqvist PH, Bensing S, Wahlberg J, Nelson LM, Gustafsson J, Husebye ES, Anderson MS, Snyder M, Kämpe O.

Sci Rep. 2016 Feb 1;6:20104. doi: 10.1038/srep20104.


Tolerance is established in polyclonal CD4(+) T cells by distinct mechanisms, according to self-peptide expression patterns.

Malhotra D, Linehan JL, Dileepan T, Lee YJ, Purtha WE, Lu JV, Nelson RW, Fife BT, Orr HT, Anderson MS, Hogquist KA, Jenkins MK.

Nat Immunol. 2016 Feb;17(2):187-95. doi: 10.1038/ni.3327. Epub 2016 Jan 4.


Central tolerance to self revealed by the autoimmune regulator.

Chan AY, Anderson MS.

Ann N Y Acad Sci. 2015 Nov;1356:80-9. doi: 10.1111/nyas.12960. Review.


Identification of a novel cis-regulatory element essential for immune tolerance.

LaFlam TN, Seumois G, Miller CN, Lwin W, Fasano KJ, Waterfield M, Proekt I, Vijayanand P, Anderson MS.

J Exp Med. 2015 Nov 16;212(12):1993-2002. doi: 10.1084/jem.20151069. Epub 2015 Nov 2.


Editorial overview: Autoimmunity.

Anderson MS, Mackay F.

Curr Opin Immunol. 2015 Dec;37:v-vii. doi: 10.1016/j.coi.2015.10.004. Epub 2015 Oct 25. Review. No abstract available.


Procalcitonin (PCT) and Kawasaki Disease: Does PCT Correlate With IVIG-Resistant Disease, Admission to the Intensive Care Unit, or Development of Coronary Artery Lesions?

Dominguez SR, Martin B, Heizer H, Jone PN, Tong S, Davidson J, Anderson MS, Glodé MP.

J Pediatric Infect Dis Soc. 2016 Sep;5(3):297-302. doi: 10.1093/jpids/piv019. Epub 2015 Apr 20.


A randomized, double-blind, placebo-controlled, short-term monotherapy study of doravirine in treatment-naive HIV-infected individuals.

Schürmann D, Sobotha C, Gilmartin J, Robberechts M, De Lepeleire I, Yee KL, Guo Y, Liu R, Wagner F, Wagner JA, Butterton JR, Anderson MS.

AIDS. 2016 Jan 2;30(1):57-63. doi: 10.1097/QAD.0000000000000876.


Concurrent Respiratory Viruses and Kawasaki Disease.

Turnier JL, Anderson MS, Heizer HR, Jone PN, Glodé MP, Dominguez SR.

Pediatrics. 2015 Sep;136(3):e609-14. doi: 10.1542/peds.2015-0950. Epub 2015 Aug 24.


Identification of MiR-205 As a MicroRNA That Is Highly Expressed in Medullary Thymic Epithelial Cells.

Khan IS, Park CY, Mavropoulos A, Shariat N, Pollack JL, Barczak AJ, Erle DJ, McManus MT, Anderson MS, Jeker LT.

PLoS One. 2015 Aug 13;10(8):e0135440. doi: 10.1371/journal.pone.0135440. eCollection 2015.


Brd4 bridges the transcriptional regulators, Aire and P-TEFb, to promote elongation of peripheral-tissue antigen transcripts in thymic stromal cells.

Yoshida H, Bansal K, Schaefer U, Chapman T, Rioja I, Proekt I, Anderson MS, Prinjha RK, Tarakhovsky A, Benoist C, Mathis D.

Proc Natl Acad Sci U S A. 2015 Aug 11;112(32):E4448-57. doi: 10.1073/pnas.1512081112. Epub 2015 Jul 27.


Transglutaminase 4 as a prostate autoantigen in male subfertility.

Landegren N, Sharon D, Shum AK, Khan IS, Fasano KJ, Hallgren Å, Kampf C, Freyhult E, Ardesjö-Lundgren B, Alimohammadi M, Rathsman S, Ludvigsson JF, Lundh D, Motrich R, Rivero V, Fong L, Giwercman A, Gustafsson J, Perheentupa J, Husebye ES, Anderson MS, Snyder M, Kämpe O.

Sci Transl Med. 2015 Jun 17;7(292):292ra101. doi: 10.1126/scitranslmed.aaa9186.


More than Meets the Eye: Monogenic Autoimmunity Strikes Again.

Anderson MS, Casanova JL.

Immunity. 2015 Jun 16;42(6):986-8. doi: 10.1016/j.immuni.2015.06.004.


Tissue Doppler Imaging as a Predictor of Immunoglobulin Resistance in Kawasaki Disease.

Phadke D, Patel SS, Dominguez SR, Heizer H, Anderson MS, Glode MP, Jone PN.

Pediatr Cardiol. 2015 Dec;36(8):1618-23. doi: 10.1007/s00246-015-1206-5. Epub 2015 May 21.


COPA mutations impair ER-Golgi transport and cause hereditary autoimmune-mediated lung disease and arthritis.

Watkin LB, Jessen B, Wiszniewski W, Vece TJ, Jan M, Sha Y, Thamsen M, Santos-Cortez RL, Lee K, Gambin T, Forbes LR, Law CS, Stray-Pedersen A, Cheng MH, Mace EM, Anderson MS, Liu D, Tang LF, Nicholas SK, Nahmod K, Makedonas G, Canter DL, Kwok PY, Hicks J, Jones KD, Penney S, Jhangiani SN, Rosenblum MD, Dell SD, Waterfield MR, Papa FR, Muzny DM, Zaitlen N, Leal SM, Gonzaga-Jauregui C; Baylor-Hopkins Center for Mendelian Genomics, Boerwinkle E, Eissa NT, Gibbs RA, Lupski JR, Orange JS, Shum AK.

Nat Genet. 2015 Jun;47(6):654-60. doi: 10.1038/ng.3279. Epub 2015 Apr 20.


Breaking through the central tolerance ceiling to unleash anticancer immune responses.

Su MA, Anderson MS.

Oncoimmunology. 2014 Aug 3;3(8):e950169. eCollection 2014.


A proposal for considering research integrity from the perspective of behavioral economics.

Anderson MS, Adam JA.

J Microbiol Biol Educ. 2014 Dec 15;15(2):173-6. doi: 10.1128/jmbe.v15i2.868. eCollection 2014 Dec. No abstract available.


Autoimmune hepatitis in a murine autoimmune polyendocrine syndrome type 1 model is directed against multiple autoantigens.

Hardtke-Wolenski M, Taubert R, Noyan F, Sievers M, Dywicki J, Schlue J, Falk CS, Ardesjö Lundgren B, Scott HS, Pich A, Anderson MS, Manns MP, Jaeckel E.

Hepatology. 2015 Apr;61(4):1295-305. doi: 10.1002/hep.27639. Epub 2015 Feb 24.


Safety, tolerability and pharmacokinetics of doravirine, a novel HIV non-nucleoside reverse transcriptase inhibitor, after single and multiple doses in healthy subjects.

Anderson MS, Gilmartin J, Cilissen C, De Lepeleire I, Van Bortel L, Dockendorf MF, Tetteh E, Ancona JK, Liu R, Guo Y, Wagner JA, Butterton JR.

Antivir Ther. 2015;20(4):397-405. doi: 10.3851/IMP2920. Epub 2014 Dec 3.


Too much of a good thing: NLRC4 and autoinflammation.

Anderson MS.

J Exp Med. 2014 Nov 17;211(12):2329. doi: 10.1084/jem.21112insight5. No abstract available.

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