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Items: 1 to 50 of 96

1.

Mapping few-femtosecond slices of ultra-relativistic electron bunches.

Plath T, Lechner C, Miltchev V, Amstutz P, Ekanayake N, Lazzarino LL, Maltezopoulos T, Bödewadt J, Laarmann T, Roßbach J.

Sci Rep. 2017 May 25;7(1):2431. doi: 10.1038/s41598-017-02184-3.

2.

Toil enables reproducible, open source, big biomedical data analyses.

Vivian J, Rao AA, Nothaft FA, Ketchum C, Armstrong J, Novak A, Pfeil J, Narkizian J, Deran AD, Musselman-Brown A, Schmidt H, Amstutz P, Craft B, Goldman M, Rosenbloom K, Cline M, O'Connor B, Hanna M, Birger C, Kent WJ, Patterson DA, Joseph AD, Zhu J, Zaranek S, Getz G, Haussler D, Paten B.

Nat Biotechnol. 2017 Apr 11;35(4):314-316. doi: 10.1038/nbt.3772. No abstract available.

3.

Filtration and Analysis of Circulating Cancer Associated Cells from the Blood of Cancer Patients.

Tang CM, Zhu P, Li S, Makarova OV, Amstutz PT, Adams DL.

Methods Mol Biol. 2017;1572:511-524. doi: 10.1007/978-1-4939-6911-1_32.

PMID:
28299708
4.

Enrichment and Molecular Analysis of Breast Cancer Disseminated Tumor Cells from Bone Marrow Using Microfiltration.

Pillai SG, Zhu P, Siddappa CM, Adams DL, Li S, Makarova OV, Amstutz P, Nunley R, Tang CM, Watson MA, Aft RL.

PLoS One. 2017 Jan 27;12(1):e0170761. doi: 10.1371/journal.pone.0170761. eCollection 2017.

5.

Free-electron laser multiplex driven by a superconducting linear accelerator.

Plath T, Amstutz P, Bödewadt J, Brenner G, Ekanayake N, Faatz B, Hacker K, Honkavaara K, Lazzarino LL, Lechner C, Maltezopoulos T, Scholz M, Schreiber S, Vogt M, Zemella J, Laarmann T.

J Synchrotron Radiat. 2016 Sep 1;23(Pt 5):1070-5. doi: 10.1107/S1600577516009620. Epub 2016 Jul 22.

PMID:
27577757
6.

Detection of tumor-associated cells in cryopreserved peripheral blood mononuclear cell samples for retrospective analysis.

Zhu P, Stanton ML, Castle EP, Joseph RW, Adams DL, Li S, Amstutz P, Tang CM, Ho TH.

J Transl Med. 2016 Jul 2;14(1):198. doi: 10.1186/s12967-016-0953-2.

7.

Polymer microfilters with nanostructured surfaces for the culture of circulating cancer cells.

Makarova OV, Adams DL, Divan R, Rosenmann D, Zhu P, Li S, Amstutz P, Tang CM.

Mater Sci Eng C Mater Biol Appl. 2016 Sep 1;66:193-198. doi: 10.1016/j.msec.2016.04.075. Epub 2016 Apr 22.

8.

The systematic study of circulating tumor cell isolation using lithographic microfilters.

Adams DL, Zhu P, Makarova OV, Martin SS, Charpentier M, Chumsri S, Li S, Amstutz P, Tang CM.

RSC Adv. 2014;9:4334-4342.

9.

Quantitative detection of zeta-chain-associated protein 70 expression in chronic lymphocytic leukemia.

Zhu P, Degheidy HA, Marti GE, Li S, Abbasi F, Wiestner A, Amstutz P, Tang CM.

Leuk Lymphoma. 2013 Mar;54(3):579-86. doi: 10.3109/10428194.2012.715349. Epub 2012 Aug 14.

10.

Detection of E. coli O157:H7 by immunomagnetic separation coupled with fluorescence immunoassay.

Zhu P, Shelton DR, Li S, Adams DL, Karns JS, Amstutz P, Tang CM.

Biosens Bioelectron. 2011 Dec 15;30(1):337-41. doi: 10.1016/j.bios.2011.09.029. Epub 2011 Oct 1.

PMID:
22005594
11.

Inhibition of ongoing allergic reactions using a novel anti-IgE DARPin-Fc fusion protein.

Eggel A, Buschor P, Baumann MJ, Amstutz P, Stadler BM, Vogel M.

Allergy. 2011 Jul;66(7):961-8. doi: 10.1111/j.1398-9995.2011.02546.x. Epub 2011 Jan 28.

PMID:
21272035
12.

DARPins against a functional IgE epitope.

Baumann MJ, Eggel A, Amstutz P, Stadler BM, Vogel M.

Immunol Lett. 2010 Oct 30;133(2):78-84. doi: 10.1016/j.imlet.2010.07.005. Epub 2010 Jul 29.

PMID:
20673836
13.

[Italian immigrants. They expect openness and empathy].

Amstutz P.

Krankenpfl Soins Infirm. 2009;102(8):24-5. German. No abstract available.

PMID:
19728640
14.

DARPins as bispecific receptor antagonists analyzed for immunoglobulin E receptor blockage.

Eggel A, Baumann MJ, Amstutz P, Stadler BM, Vogel M.

J Mol Biol. 2009 Oct 30;393(3):598-607. doi: 10.1016/j.jmb.2009.08.014. Epub 2009 Aug 13.

PMID:
19683003
15.

Multiplex integrating waveguide sensor: signalyte-II.

Li S, Zhang Y, Amstutz P 3rd, Tang CM.

Methods Mol Biol. 2009;503:423-34. doi: 10.1007/978-1-60327-567-5_24.

PMID:
19151956
16.

Integrating waveguide biosensor.

Li S, Amstutz P 3rd, Tang CM, Hang J, Zhu P, Zhang Y, Shelton DR, Karns JS.

Methods Mol Biol. 2009;503:389-401. doi: 10.1007/978-1-60327-567-5_22.

PMID:
19151954
17.

CD4-specific designed ankyrin repeat proteins are novel potent HIV entry inhibitors with unique characteristics.

Schweizer A, Rusert P, Berlinger L, Ruprecht CR, Mann A, Corthésy S, Turville SG, Aravantinou M, Fischer M, Robbiani M, Amstutz P, Trkola A.

PLoS Pathog. 2008 Jul 25;4(7):e1000109. doi: 10.1371/journal.ppat.1000109.

18.

DARPins: a new generation of protein therapeutics.

Stumpp MT, Binz HK, Amstutz P.

Drug Discov Today. 2008 Aug;13(15-16):695-701. doi: 10.1016/j.drudis.2008.04.013. Epub 2008 Jul 11. Review.

PMID:
18621567
19.

Acid-base balance.

Offenstadt G, Amstutz P.

Crit Care Med. 2008 May;36(5):1690-1; author reply 1691. doi: 10.1097/CCM.0b013e318171160c. No abstract available.

PMID:
18448949
20.

Development of a rapid and sensitive immunoassay for detection and subsequent recovery of Bacillus anthracis spores in environmental samples.

Hang J, Sundaram AK, Zhu P, Shelton DR, Karns JS, Martin PA, Li S, Amstutz P, Tang CM.

J Microbiol Methods. 2008 Jun;73(3):242-6. doi: 10.1016/j.mimet.2008.02.018. Epub 2008 Mar 2.

21.

Structure of wild-type Plk-1 kinase domain in complex with a selective DARPin.

Bandeiras TM, Hillig RC, Matias PM, Eberspaecher U, Fanghänel J, Thomaz M, Miranda S, Crusius K, Pütter V, Amstutz P, Gulotti-Georgieva M, Binz HK, Holz C, Schmitz AA, Lang C, Donner P, Egner U, Carrondo MA, Müller-Tiemann B.

Acta Crystallogr D Biol Crystallogr. 2008 Apr;64(Pt 4):339-53. doi: 10.1107/S0907444907068217. Epub 2008 Mar 19.

PMID:
18391401
22.

Designed ankyrin repeat proteins as anti-idiotypic-binding molecules.

Vogel M, Keller-Gautschi E, Baumann MJ, Amstutz P, Ruf C, Kricek F, Stadler BM.

Ann N Y Acad Sci. 2007 Aug;1109:9-18.

PMID:
17785285
23.

Inhibition of caspase-2 by a designed ankyrin repeat protein: specificity, structure, and inhibition mechanism.

Schweizer A, Roschitzki-Voser H, Amstutz P, Briand C, Gulotti-Georgieva M, Prenosil E, Binz HK, Capitani G, Baici A, Plückthun A, Grütter MG.

Structure. 2007 May;15(5):625-36.

24.

DARPins: a true alternative to antibodies.

Stumpp MT, Amstutz P.

Curr Opin Drug Discov Devel. 2007 Mar;10(2):153-9. Review.

PMID:
17436550
25.

Ribosome display: selecting and evolving proteins in vitro that specifically bind to a target.

Zahnd C, Amstutz P, Plückthun A.

Nat Methods. 2007 Mar;4(3):269-79.

PMID:
17327848
26.

Drug export pathway of multidrug exporter AcrB revealed by DARPin inhibitors.

Sennhauser G, Amstutz P, Briand C, Storchenegger O, Grütter MG.

PLoS Biol. 2007 Jan;5(1):e7.

27.

Isolation of intracellular proteinase inhibitors derived from designed ankyrin repeat proteins by genetic screening.

Kawe M, Forrer P, Amstutz P, Plückthun A.

J Biol Chem. 2006 Dec 29;281(52):40252-63. Epub 2006 Oct 18.

28.

Rapid selection of specific MAP kinase-binders from designed ankyrin repeat protein libraries.

Amstutz P, Koch H, Binz HK, Deuber SA, Plückthun A.

Protein Eng Des Sel. 2006 May;19(5):219-29. Epub 2006 Mar 21.

PMID:
16551653
29.

Engineering novel binding proteins from nonimmunoglobulin domains.

Binz HK, Amstutz P, Plückthun A.

Nat Biotechnol. 2005 Oct;23(10):1257-68. Review.

PMID:
16211069
30.

Detection of water-borne E. coli O157 using the integrating waveguide biosensor.

Zhu P, Shelton DR, Karns JS, Sundaram A, Li S, Amstutz P, Tang CM.

Biosens Bioelectron. 2005 Oct 15;21(4):678-83.

31.

Allosteric inhibition of aminoglycoside phosphotransferase by a designed ankyrin repeat protein.

Kohl A, Amstutz P, Parizek P, Binz HK, Briand C, Capitani G, Forrer P, Plückthun A, Grütter MG.

Structure. 2005 Aug;13(8):1131-41.

32.

Intracellular kinase inhibitors selected from combinatorial libraries of designed ankyrin repeat proteins.

Amstutz P, Binz HK, Parizek P, Stumpp MT, Kohl A, Grütter MG, Forrer P, Plückthun A.

J Biol Chem. 2005 Jul 1;280(26):24715-22. Epub 2005 Apr 25.

33.

High-affinity binders selected from designed ankyrin repeat protein libraries.

Binz HK, Amstutz P, Kohl A, Stumpp MT, Briand C, Forrer P, Grütter MG, Plückthun A.

Nat Biotechnol. 2004 May;22(5):575-82. Epub 2004 Apr 18.

PMID:
15097997
34.

Directed in vitro evolution and crystallographic analysis of a peptide-binding single chain antibody fragment (scFv) with low picomolar affinity.

Zahnd C, Spinelli S, Luginbühl B, Amstutz P, Cambillau C, Plückthun A.

J Biol Chem. 2004 Apr 30;279(18):18870-7. Epub 2004 Jan 30.

35.

Designing repeat proteins: well-expressed, soluble and stable proteins from combinatorial libraries of consensus ankyrin repeat proteins.

Binz HK, Stumpp MT, Forrer P, Amstutz P, Plückthun A.

J Mol Biol. 2003 Sep 12;332(2):489-503.

PMID:
12948497
36.

In vitro selection for catalytic activity with ribosome display.

Amstutz P, Pelletier JN, Guggisberg A, Jermutus L, Cesaro-Tadic S, Zahnd C, Plückthun A.

J Am Chem Soc. 2002 Aug 14;124(32):9396-403.

PMID:
12167034
37.

In vitro display technologies: novel developments and applications.

Amstutz P, Forrer P, Zahnd C, Plückthun A.

Curr Opin Biotechnol. 2001 Aug;12(4):400-5. Review.

PMID:
11551470
38.

Influence of acute renal failure on FPIA rapid serum assay of midazolam and its main metabolite.

Bouton V, Bourget P, Lesne-Hulin A, Amstutz P, Benayed M, Benhamou D, Dufieux JL, Goursot G, Grobuis S, Haberer JP, Jardin F, Kirstetter P, Marty J, Mercatello A, Page B, Pourriat JL, Vassal T.

Int J Clin Pharmacol Ther. 1997 Nov;35(11):531-8.

PMID:
9401837
39.

Comparison of high-performance liquid chromatography and polyclonal fluorescence polarization immunoassay for the monitoring of midazolam in the plasma of intensive care unit patients.

Bourget P, Bouton V, Lesne-Hulin A, Amstutz P, Benayed M, Benhamou D, Dufieux PL, Goursot G, Grosbuis S, Haberer JP, Jardin F, Kirstetter P, Marty J, Mercatello A, Page B, Pourriat JL, Vassal T.

Ther Drug Monit. 1996 Oct;18(5):610-9.

PMID:
8885128
40.

[Disseminated intravascular coagulations].

Amstutz P, Moyo JS.

Cah Anesthesiol. 1996;44(3):219-28. Review. French.

PMID:
9005011
41.

[Efficacy and tolerance of Elohes in plasma exchanges].

Guidet B, Staikowsky F, Vassal T, Offenstadt G, Amstutz P.

Ann Fr Anesth Reanim. 1992;11(5):534-9. French.

PMID:
1476285
42.

[The results of antibiotic therapy in acute severe pneumonia dependent on the initial severity].

Amstutz P, Blanloeil Y, Cathala B, Chopin C, Gouin F, Grimaud D, Le Gall JR, Rouby JJ, Tempe JD, Vanooteghem-Delbarre A, et al.

Presse Med. 1990 Dec 8;19(42):1948. French. No abstract available.

PMID:
2147761
43.

Tumor necrosis factor and septic shock.

Baud L, Cadranel J, Offenstadt G, Luguel L, Guidet B, Amstutz P.

Crit Care Med. 1990 Mar;18(3):349-50. No abstract available.

PMID:
2302971
44.

[Specificity and serum concentrations of tumor necrosis factor in septic shock].

Guidet B, Luquel L, Cadranel J, Baud L, Offenstadt G, Amstutz P.

Ann Med Interne (Paris). 1990;141(6):515-8. French.

PMID:
2285204
45.

Capillary leakage complicated by compartment syndrome necessitating surgery.

Guidet B, Guerin B, Maury E, Offenstadt G, Amstutz P.

Intensive Care Med. 1990;16(5):332-3.

PMID:
2212261
46.

[Lethal hemorrhagic syndrome after mithramycin. Lack of platelet aggregation and inhibitor of factor V].

Thomas F, Robert A, Luquel L, Dombret H, Offenstadt G, Amstutz P.

Presse Med. 1989 Feb 4;18(4):182. French. No abstract available.

PMID:
2522204
47.

Polycythemia in chronic obstructive pulmonary disease. A study of serum and urine erythropoietin and medullary erythroid progenitors.

Guidet B, Offenstadt G, Boffa G, Najman A, Baillou C, Hatzfeld C, Amstutz P.

Chest. 1987 Nov;92(5):867-70.

PMID:
3665602
48.

[Fatal pulmonary pneumocystosis 2 years after multiple transfusions. Results of a transfusion study].

Mercadier A, Geay-Chicot D, Baudelot J, Offenstadt G, Guidet B, Amstutz P.

Presse Med. 1986 Feb 1;15(4):164-5. French. No abstract available.

PMID:
2938123
49.

[Spontaneous pneumothorax: drainage by catheter or chest tube?].

Burgaud JC, Offenstadt G, Bencharif G, Hericord P, Amstutz P.

Rev Pneumol Clin. 1985;41(5):317-9. French.

PMID:
4095427
50.

Temocillin treatment of serious infections due to gram-negative bacilli in an intensive care unit.

Offenstadt G, Lesage D, Hericord P, Pinta P, Leaute JB, Amstutz P.

Drugs. 1985;29 Suppl 5:213-20.

PMID:
3896741

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