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Items: 21

1.

Hepatitis delta virus persists during liver regeneration and is amplified through cell division both in vitro and in vivo.

Giersch K, Bhadra OD, Volz T, Allweiss L, Riecken K, Fehse B, Lohse AW, Petersen J, Sureau C, Urban S, Dandri M, Lütgehetmann M.

Gut. 2017 Dec 7. pii: gutjnl-2017-314713. doi: 10.1136/gutjnl-2017-314713. [Epub ahead of print]

PMID:
29217749
2.

Efficacy of NVR 3-778, Alone and In Combination With Pegylated Interferon, vs Entecavir In uPA/SCID Mice With Humanized Livers and HBV Infection.

Klumpp K, Shimada T, Allweiss L, Volz T, Lütgehetmann M, Hartman G, Flores OA, Lam AM, Dandri M.

Gastroenterology. 2018 Feb;154(3):652-662.e8. doi: 10.1053/j.gastro.2017.10.017. Epub 2017 Oct 24.

PMID:
29079518
3.

Lymphocytes transiently expressing virus-specific T cell receptors reduce hepatitis B virus infection.

Kah J, Koh S, Volz T, Ceccarello E, Allweiss L, Lütgehetmann M, Bertoletti A, Dandri M.

J Clin Invest. 2017 Aug 1;127(8):3177-3188. doi: 10.1172/JCI93024. Epub 2017 Jul 24.

4.

The Role of cccDNA in HBV Maintenance.

Allweiss L, Dandri M.

Viruses. 2017 Jun 21;9(6). pii: E156. doi: 10.3390/v9060156. Review.

5.

Both interferon alpha and lambda can reduce all intrahepatic HDV infection markers in HBV/HDV infected humanized mice.

Giersch K, Homs M, Volz T, Helbig M, Allweiss L, Lohse AW, Petersen J, Buti M, Pollicino T, Sureau C, Dandri M, Lütgehetmann M.

Sci Rep. 2017 Jun 16;7(1):3757. doi: 10.1038/s41598-017-03946-9.

6.

Proliferation of primary human hepatocytes and prevention of hepatitis B virus reinfection efficiently deplete nuclear cccDNA in vivo.

Allweiss L, Volz T, Giersch K, Kah J, Raffa G, Petersen J, Lohse AW, Beninati C, Pollicino T, Urban S, Lütgehetmann M, Dandri M.

Gut. 2018 Mar;67(3):542-552. doi: 10.1136/gutjnl-2016-312162. Epub 2017 Apr 20.

PMID:
28428345
7.
8.

Serum HBV pgRNA as a clinical marker for cccDNA activity.

Giersch K, Allweiss L, Volz T, Dandri M, Lütgehetmann M.

J Hepatol. 2017 Feb;66(2):460-462. doi: 10.1016/j.jhep.2016.09.028. Epub 2016 Nov 5. No abstract available.

PMID:
27826059
9.

Experimental in vitro and in vivo models for the study of human hepatitis B virus infection.

Allweiss L, Dandri M.

J Hepatol. 2016 Apr;64(1 Suppl):S17-S31. doi: 10.1016/j.jhep.2016.02.012. Review.

PMID:
27084033
10.

Primary Human Hepatocytes Repopulate Livers of Mice After In Vitro Culturing and Lentiviral-Mediated Gene Transfer.

Bierwolf J, Volz T, Lütgehetmann M, Allweiss L, Riecken K, Warlich M, Fehse B, Kalff JC, Dandri M, Pollok JM.

Tissue Eng Part A. 2016 May;22(9-10):742-53. doi: 10.1089/ten.TEA.2015.0427.

11.

Human liver chimeric mice as a new model of chronic hepatitis E virus infection and preclinical drug evaluation.

Allweiss L, Gass S, Giersch K, Groth A, Kah J, Volz T, Rapp G, Schöbel A, Lohse AW, Polywka S, Pischke S, Herker E, Dandri M, Lütgehetmann M.

J Hepatol. 2016 May;64(5):1033-1040. doi: 10.1016/j.jhep.2016.01.011. Epub 2016 Jan 22.

PMID:
26805671
12.

Hepatitis Delta co-infection in humanized mice leads to pronounced induction of innate immune responses in comparison to HBV mono-infection.

Giersch K, Allweiss L, Volz T, Helbig M, Bierwolf J, Lohse AW, Pollok JM, Petersen J, Dandri M, Lütgehetmann M.

J Hepatol. 2015 Aug;63(2):346-53. doi: 10.1016/j.jhep.2015.03.011. Epub 2015 Mar 17.

PMID:
25795587
13.

Binding of hepatitis B virus to its cellular receptor alters the expression profile of genes of bile acid metabolism.

Oehler N, Volz T, Bhadra OD, Kah J, Allweiss L, Giersch K, Bierwolf J, Riecken K, Pollok JM, Lohse AW, Fehse B, Petersen J, Urban S, Lütgehetmann M, Heeren J, Dandri M.

Hepatology. 2014 Nov;60(5):1483-93. doi: 10.1002/hep.27159. Epub 2014 May 19.

PMID:
24711282
14.

Immune cell responses are not required to induce substantial hepatitis B virus antigen decline during pegylated interferon-alpha administration.

Allweiss L, Volz T, Lütgehetmann M, Giersch K, Bornscheuer T, Lohse AW, Petersen J, Ma H, Klumpp K, Fletcher SP, Dandri M.

J Hepatol. 2014 Mar;60(3):500-7. doi: 10.1016/j.jhep.2013.10.021. Epub 2013 Oct 26.

PMID:
24398036
15.

Persistent hepatitis D virus mono-infection in humanized mice is efficiently converted by hepatitis B virus to a productive co-infection.

Giersch K, Helbig M, Volz T, Allweiss L, Mancke LV, Lohse AW, Polywka S, Pollok JM, Petersen J, Taylor J, Dandri M, Lütgehetmann M.

J Hepatol. 2014 Mar;60(3):538-44. doi: 10.1016/j.jhep.2013.11.010. Epub 2013 Nov 23.

PMID:
24280293
16.

The entry inhibitor Myrcludex-B efficiently blocks intrahepatic virus spreading in humanized mice previously infected with hepatitis B virus.

Volz T, Allweiss L, Ben MBarek M, Warlich M, Lohse AW, Pollok JM, Alexandrov A, Urban S, Petersen J, Lütgehetmann M, Dandri M.

J Hepatol. 2013 May;58(5):861-7. doi: 10.1016/j.jhep.2012.12.008. Epub 2012 Dec 13.

PMID:
23246506
17.

Strong antiviral activity of the new l-hydroxycytidine derivative, l-Hyd4FC, in HBV-infected human chimeric uPA/SCID mice.

Volz T, Lütgehetmann M, Allweiss L, Warlich M, Bierwolf J, Pollok JM, Petersen J, Matthes E, Dandri M.

Antivir Ther. 2012;17(4):623-31. doi: 10.3851/IMP2075. Epub 2012 Feb 27.

PMID:
22368233
18.

IFN-α inhibits HBV transcription and replication in cell culture and in humanized mice by targeting the epigenetic regulation of the nuclear cccDNA minichromosome.

Belloni L, Allweiss L, Guerrieri F, Pediconi N, Volz T, Pollicino T, Petersen J, Raimondo G, Dandri M, Levrero M.

J Clin Invest. 2012 Feb;122(2):529-37. doi: 10.1172/JCI58847. Epub 2012 Jan 17.

19.

Humanized chimeric uPA mouse model for the study of hepatitis B and D virus interactions and preclinical drug evaluation.

Lütgehetmann M, Mancke LV, Volz T, Helbig M, Allweiss L, Bornscheuer T, Pollok JM, Lohse AW, Petersen J, Urban S, Dandri M.

Hepatology. 2012 Mar;55(3):685-94. doi: 10.1002/hep.24758. Epub 2012 Jan 30.

PMID:
22031488
20.

Hepatitis B virus limits response of human hepatocytes to interferon-α in chimeric mice.

Lütgehetmann M, Bornscheuer T, Volz T, Allweiss L, Bockmann JH, Pollok JM, Lohse AW, Petersen J, Dandri M.

Gastroenterology. 2011 Jun;140(7):2074-83, 2083.e1-2. doi: 10.1053/j.gastro.2011.02.057. Epub 2011 Mar 2.

PMID:
21376046
21.

Specificity protein 2 (Sp2) is essential for mouse development and autonomous proliferation of mouse embryonic fibroblasts.

Baur F, Nau K, Sadic D, Allweiss L, Elsässer HP, Gillemans N, de Wit T, Krüger I, Vollmer M, Philipsen S, Suske G.

PLoS One. 2010 Mar 8;5(3):e9587. doi: 10.1371/journal.pone.0009587.

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