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Items: 1 to 50 of 68

1.

Diminished nuclear RNA decay upon Salmonella infection upregulates antibacterial noncoding RNAs.

Imamura K, Takaya A, Ishida YI, Fukuoka Y, Taya T, Nakaki R, Kakeda M, Imamachi N, Sato A, Yamada T, Onoguchi-Mizutani R, Akizuki G, Tanu T, Tao K, Miyao S, Suzuki Y, Nagahama M, Yamamoto T, Jensen TH, Akimitsu N.

EMBO J. 2018 Jun 7. pii: e97723. doi: 10.15252/embj.201797723. [Epub ahead of print]

PMID:
29880601
2.

Identification of Minimal p53 Promoter Region Regulated by MALAT1 in Human Lung Adenocarcinoma Cells.

Tano K, Onoguchi-Mizutani R, Yeasmin F, Uchiumi F, Suzuki Y, Yada T, Akimitsu N.

Front Genet. 2018 Mar 26;8:208. doi: 10.3389/fgene.2017.00208. eCollection 2017.

3.

5'-Bromouridine IP Chase (BRIC)-Seq to Determine RNA Half-Lives.

Yamada T, Imamachi N, Onoguchi-Mizutani R, Imamura K, Suzuki Y, Akimitsu N.

Methods Mol Biol. 2018;1720:1-13. doi: 10.1007/978-1-4939-7540-2_1.

PMID:
29236247
4.

Four Aromatic Sulfates with an Inhibitory Effect against HCV NS3 Helicase from the Crinoid Alloeocomatella polycladia.

Hermawan I, Furuta A, Higashi M, Fujita Y, Akimitsu N, Yamashita A, Moriishi K, Tsuneda S, Tani H, Nakakoshi M, Tsubuki M, Sekiguchi Y, Noda N, Tanaka J.

Mar Drugs. 2017 Apr 11;15(4). pii: E117. doi: 10.3390/md15040117.

5.

Expression of Cadherin-17 Promotes Metastasis in a Highly Bone Marrow Metastatic Murine Breast Cancer Model.

Okada T, Kurabayashi A, Akimitsu N, Furihata M.

Biomed Res Int. 2017;2017:8494286. doi: 10.1155/2017/8494286. Epub 2017 Jan 19.

6.

A GC-rich sequence feature in the 3' UTR directs UPF1-dependent mRNA decay in mammalian cells.

Imamachi N, Salam KA, Suzuki Y, Akimitsu N.

Genome Res. 2017 Mar;27(3):407-418. doi: 10.1101/gr.206060.116. Epub 2016 Dec 9.

7.

Preliminary investigation of five novel long non-coding RNAs in hepatocellular carcinoma cell lines.

Xia J, Inagaki Y, Sawakami T, Song P, Cai Y, Hasegawa K, Sakamoto Y, Akimitsu N, Tang W, Kokudo N.

Biosci Trends. 2016 Sep 5;10(4):315-9. doi: 10.5582/bst.2016.01140. Epub 2016 Aug 5.

8.

Effects of Chronic Low-Dose Radiation on Human Neural Progenitor Cells.

Katsura M, Cyou-Nakamine H, Zen Q, Zen Y, Nansai H, Amagasa S, Kanki Y, Inoue T, Kaneki K, Taguchi A, Kobayashi M, Kaji T, Kodama T, Miyagawa K, Wada Y, Akimitsu N, Sone H.

Sci Rep. 2016 Jan 22;6:20027. doi: 10.1038/srep20027.

9.

[Regulation of innate immune responses by long noncoding RNAs].

Akimitsu N.

Seikagaku. 2015 Jun;87(3):385-8. Review. Japanese. No abstract available.

PMID:
26571607
10.

Oncofetal protein IGF2BP3 facilitates the activity of proto-oncogene protein eIF4E through the destabilization of EIF4E-BP2 mRNA.

Mizutani R, Imamachi N, Suzuki Y, Yoshida H, Tochigi N, Oonishi T, Suzuki Y, Akimitsu N.

Oncogene. 2016 Jul 7;35(27):3495-502. doi: 10.1038/onc.2015.410. Epub 2015 Nov 2.

PMID:
26522719
11.

Identification of Hydroxyanthraquinones as Novel Inhibitors of Hepatitis C Virus NS3 Helicase.

Furuta A, Tsubuki M, Endoh M, Miyamoto T, Tanaka J, Salam KA, Akimitsu N, Tani H, Yamashita A, Moriishi K, Nakakoshi M, Sekiguchi Y, Tsuneda S, Noda N.

Int J Mol Sci. 2015 Aug 7;16(8):18439-53. doi: 10.3390/ijms160818439.

12.

Analysis of RNA decay factor mediated RNA stability contributions on RNA abundance.

Maekawa S, Imamachi N, Irie T, Tani H, Matsumoto K, Mizutani R, Imamura K, Kakeda M, Yada T, Sugano S, Suzuki Y, Akimitsu N.

BMC Genomics. 2015 Mar 6;16:154. doi: 10.1186/s12864-015-1358-y.

13.

A fluorescence-based screening assay for identification of hepatitis C virus NS3 helicase inhibitors and characterization of their inhibitory mechanism.

Furuta A, Salam KA, Tani H, Tsuneda S, Sekiguchi Y, Akimitsu N, Noda N.

Methods Mol Biol. 2015;1259:211-28. doi: 10.1007/978-1-4939-2214-7_14.

PMID:
25579589
14.

Genome-wide analysis of long noncoding RNA turnover.

Tani H, Imamachi N, Mizutani R, Imamura K, Kwon Y, Miyazaki S, Maekawa S, Suzuki Y, Akimitsu N.

Methods Mol Biol. 2015;1262:305-20. doi: 10.1007/978-1-4939-2253-6_19.

PMID:
25555590
15.

Long Non-Coding RNAs Involved in Immune Responses.

Imamura K, Akimitsu N.

Front Immunol. 2014 Nov 13;5:573. doi: 10.3389/fimmu.2014.00573. eCollection 2014. Review.

16.

PBDE: structure-activity studies for the inhibition of hepatitis C virus NS3 helicase.

Salam KA, Furuta A, Noda N, Tsuneda S, Sekiguchi Y, Yamashita A, Moriishi K, Nakakoshi M, Tani H, Roy SR, Tanaka J, Tsubuki M, Akimitsu N.

Molecules. 2014 Apr 2;19(4):4006-20. doi: 10.3390/molecules19044006.

17.

Long noncoding RNA NEAT1-dependent SFPQ relocation from promoter region to paraspeckle mediates IL8 expression upon immune stimuli.

Imamura K, Imamachi N, Akizuki G, Kumakura M, Kawaguchi A, Nagata K, Kato A, Kawaguchi Y, Sato H, Yoneda M, Kai C, Yada T, Suzuki Y, Yamada T, Ozawa T, Kaneki K, Inoue T, Kobayashi M, Kodama T, Wada Y, Sekimizu K, Akimitsu N.

Mol Cell. 2014 Feb 6;53(3):393-406. doi: 10.1016/j.molcel.2014.01.009. Erratum in: Mol Cell. 2014 Jun 19;54(6):1055.

18.

Identification and biochemical characterization of halisulfate 3 and suvanine as novel inhibitors of hepatitis C virus NS3 helicase from a marine sponge.

Furuta A, Salam KA, Hermawan I, Akimitsu N, Tanaka J, Tani H, Yamashita A, Moriishi K, Nakakoshi M, Tsubuki M, Peng PW, Suzuki Y, Yamamoto N, Sekiguchi Y, Tsuneda S, Noda N.

Mar Drugs. 2014 Jan 21;12(1):462-76. doi: 10.3390/md12010462.

19.

Hepatitis C virus NS3 inhibitors: current and future perspectives.

Salam KA, Akimitsu N.

Biomed Res Int. 2013;2013:467869. doi: 10.1155/2013/467869. Epub 2013 Oct 27. Review.

20.

BRIC-seq: a genome-wide approach for determining RNA stability in mammalian cells.

Imamachi N, Tani H, Mizutani R, Imamura K, Irie T, Suzuki Y, Akimitsu N.

Methods. 2014 May 1;67(1):55-63. doi: 10.1016/j.ymeth.2013.07.014. Epub 2013 Jul 17.

PMID:
23872059
21.

Cholesterol sulfate as a potential inhibitor of hepatitis C virus NS3 helicase.

Furuta A, Salam KA, Akimitsu N, Tanaka J, Tani H, Yamashita A, Moriishi K, Nakakoshi M, Tsubuki M, Sekiguchi Y, Tsuneda S, Noda N.

J Enzyme Inhib Med Chem. 2014 Apr;29(2):223-9. doi: 10.3109/14756366.2013.766607. Epub 2013 Feb 25.

PMID:
23432541
22.

The RNA degradation pathway regulates the function of GAS5 a non-coding RNA in mammalian cells.

Tani H, Torimura M, Akimitsu N.

PLoS One. 2013;8(1):e55684. doi: 10.1371/journal.pone.0055684. Epub 2013 Jan 30.

23.

Psammaplin A inhibits hepatitis C virus NS3 helicase.

Salam KA, Furuta A, Noda N, Tsuneda S, Sekiguchi Y, Yamashita A, Moriishi K, Nakakoshi M, Tsubuki M, Tani H, Tanaka J, Akimitsu N.

J Nat Med. 2013 Oct;67(4):765-72. doi: 10.1007/s11418-013-0742-7. Epub 2013 Jan 29.

PMID:
23359228
24.

Inhibition of both protease and helicase activities of hepatitis C virus NS3 by an ethyl acetate extract of marine sponge Amphimedon sp.

Fujimoto Y, Salam KA, Furuta A, Matsuda Y, Fujita O, Tani H, Ikeda M, Kato N, Sakamoto N, Maekawa S, Enomoto N, de Voogd NJ, Nakakoshi M, Tsubuki M, Sekiguchi Y, Tsuneda S, Akimitsu N, Noda N, Yamashita A, Tanaka J, Moriishi K.

PLoS One. 2012;7(11):e48685. doi: 10.1371/journal.pone.0048685. Epub 2012 Nov 7.

25.

Long non-coding RNAs in cancer progression.

Tano K, Akimitsu N.

Front Genet. 2012 Oct 24;3:219. doi: 10.3389/fgene.2012.00219. eCollection 2012.

26.

Identification of hundreds of novel UPF1 target transcripts by direct determination of whole transcriptome stability.

Tani H, Imamachi N, Salam KA, Mizutani R, Ijiri K, Irie T, Yada T, Suzuki Y, Akimitsu N.

RNA Biol. 2012 Nov;9(11):1370-9. doi: 10.4161/rna.22360. Epub 2012 Oct 12.

27.
28.

Inhibition of hepatitis C virus replication and viral helicase by ethyl acetate extract of the marine feather star Alloeocomatella polycladia.

Yamashita A, Salam KA, Furuta A, Matsuda Y, Fujita O, Tani H, Fujita Y, Fujimoto Y, Ikeda M, Kato N, Sakamoto N, Maekawa S, Enomoto N, Nakakoshi M, Tsubuki M, Sekiguchi Y, Tsuneda S, Akimitsu N, Noda N, Tanaka J, Moriishi K.

Mar Drugs. 2012 Apr;10(4):744-61. doi: 10.3390/md10040744. Epub 2012 Mar 28.

29.

Up-frameshift protein 1 (UPF1): multitalented entertainer in RNA decay.

Imamachi N, Tani H, Akimitsu N.

Drug Discov Ther. 2012 Apr;6(2):55-61. Review.

30.

Identification and characterization of novel genotoxic stress-inducible nuclear long noncoding RNAs in mammalian cells.

Mizutani R, Wakamatsu A, Tanaka N, Yoshida H, Tochigi N, Suzuki Y, Oonishi T, Tani H, Tano K, Ijiri K, Isogai T, Akimitsu N.

PLoS One. 2012;7(4):e34949. doi: 10.1371/journal.pone.0034949. Epub 2012 Apr 19.

31.

Inhibition of hepatitis C virus NS3 helicase by manoalide.

Salam KA, Furuta A, Noda N, Tsuneda S, Sekiguchi Y, Yamashita A, Moriishi K, Nakakoshi M, Tsubuki M, Tani H, Tanaka J, Akimitsu N.

J Nat Prod. 2012 Apr 27;75(4):650-4. doi: 10.1021/np200883s. Epub 2012 Mar 6.

PMID:
22394195
32.

Genome-wide determination of RNA stability reveals hundreds of short-lived noncoding transcripts in mammals.

Tani H, Mizutani R, Salam KA, Tano K, Ijiri K, Wakamatsu A, Isogai T, Suzuki Y, Akimitsu N.

Genome Res. 2012 May;22(5):947-56. doi: 10.1101/gr.130559.111. Epub 2012 Feb 27. Erratum in: Genome Res. 2012 Jul;22(7):1382.

33.

Identification of cis- and trans-acting factors involved in the localization of MALAT-1 noncoding RNA to nuclear speckles.

Miyagawa R, Tano K, Mizuno R, Nakamura Y, Ijiri K, Rakwal R, Shibato J, Masuo Y, Mayeda A, Hirose T, Akimitsu N.

RNA. 2012 Apr;18(4):738-51. doi: 10.1261/rna.028639.111. Epub 2012 Feb 21.

34.

MALAT-1 enhances cell motility of lung adenocarcinoma cells by influencing the expression of motility-related genes.

Tano K, Mizuno R, Okada T, Rakwal R, Shibato J, Masuo Y, Ijiri K, Akimitsu N.

FEBS Lett. 2010 Nov 19;584(22):4575-80. doi: 10.1016/j.febslet.2010.10.008. Epub 2010 Oct 13.

35.

Reduced expression of Sytl 1 and Ccdc21 and impaired induction of Mt I by oxidative stress in SII-K1 knockout mice.

Tano K, Hamamoto H, Ito T, Sumiya E, Rakwal R, Shibato J, Masuo Y, Ijiri K, Sekimizu K, Akimitsu N.

Drug Discov Ther. 2010 Oct;4(5):368-72.

36.

Stability of MALAT-1, a nuclear long non-coding RNA in mammalian cells, varies in various cancer cells.

Tani H, Nakamura Y, Ijiri K, Akimitsu N.

Drug Discov Ther. 2010 Aug;4(4):235-9.

37.

Real-time monitoring of RNA helicase activity using fluorescence resonance energy transfer in vitro.

Tani H, Fujita O, Furuta A, Matsuda Y, Miyata R, Akimitsu N, Tanaka J, Tsuneda S, Sekiguchi Y, Noda N.

Biochem Biophys Res Commun. 2010 Feb 26;393(1):131-6. doi: 10.1016/j.bbrc.2010.01.100. Epub 2010 Feb 1.

PMID:
20117090
38.

High-throughput screening assay of hepatitis C virus helicase inhibitors using fluorescence-quenching phenomenon.

Tani H, Akimitsu N, Fujita O, Matsuda Y, Miyata R, Tsuneda S, Igarashi M, Sekiguchi Y, Noda N.

Biochem Biophys Res Commun. 2009 Feb 20;379(4):1054-9. doi: 10.1016/j.bbrc.2009.01.020. Epub 2009 Jan 14.

PMID:
19150342
39.

S-II mediated gene regulation.

Tano K, Nagata M, Akimitsu N.

Drug Discov Ther. 2008 Jun;2(3):136-9.

40.

Roles of the Duffy antigen and glycophorin A in malaria infectionand erythrocyte.

Hamamoto H, Akimitsu N, Arimitsu N, Sekimizu K.

Drug Discov Ther. 2008 Apr;2(2):58-63.

41.

A highly bone marrow metastatic murine breast cancer model established through in vivo selection exhibits enhanced anchorage-independent growth and cell migration mediated by ICAM-1.

Takahashi M, Furihata M, Akimitsu N, Watanabe M, Kaul S, Yumoto N, Okada T.

Clin Exp Metastasis. 2008;25(5):517-29. doi: 10.1007/s10585-008-9163-5. Epub 2008 Mar 14.

PMID:
18340424
42.

Messenger RNA surveillance systems monitoring proper translation termination.

Akimitsu N.

J Biochem. 2008 Jan;143(1):1-8. Epub 2007 Nov 1. Review.

PMID:
17981821
43.

Glycophorin A-knockout mice, which lost sialoglycoproteins from the red blood cell membrane, are resistant to lethal infection of Babesia rodhaini.

Takabatake N, Okamura M, Yokoyama N, Ikehara Y, Akimitsu N, Arimitsu N, Hamamoto H, Sekimizu K, Suzuki H, Igarashi I.

Vet Parasitol. 2007 Sep 1;148(2):93-101. Epub 2007 Jul 24.

PMID:
17651898
44.

Translation of nonSTOP mRNA is repressed post-initiation in mammalian cells.

Akimitsu N, Tanaka J, Pelletier J.

EMBO J. 2007 May 2;26(9):2327-38. Epub 2007 Apr 19.

45.

Transcription elongation factor S-II is required for definitive hematopoiesis.

Ito T, Arimitsu N, Takeuchi M, Kawamura N, Nagata M, Saso K, Akimitsu N, Hamamoto H, Natori S, Miyajima A, Sekimizu K.

Mol Cell Biol. 2006 Apr;26(8):3194-203.

46.

Direct interaction between metastasis-associated protein 1 and endophilin 3.

Aramaki Y, Ogawa K, Toh Y, Ito T, Akimitsu N, Hamamoto H, Sekimizu K, Matsusue K, Kono A, Iguchi H, Takiguchi S.

FEBS Lett. 2005 Jul 4;579(17):3731-6.

47.

Erythrocyte surface glycosylphosphatidyl inositol anchored receptor for the malaria parasite.

Rungruang T, Kaneko O, Murakami Y, Tsuboi T, Hamamoto H, Akimitsu N, Sekimizu K, Kinoshita T, Torii M.

Mol Biochem Parasitol. 2005 Mar;140(1):13-21.

PMID:
15694483
48.

DNA topoisomerase II is required for the G0-to-S phase transition in Drosophila Schneider cells, but not in yeast.

Hossain MS, Kurokawa K, Akimitsu N, Sekimizu K.

Genes Cells. 2004 Oct;9(10):905-17.

49.

DiaA, a novel DnaA-binding protein, ensures the timely initiation of Escherichia coli chromosome replication.

Ishida T, Akimitsu N, Kashioka T, Hatano M, Kubota T, Ogata Y, Sekimizu K, Katayama T.

J Biol Chem. 2004 Oct 29;279(44):45546-55. Epub 2004 Aug 23.

50.

Duffy antigen is important for the lethal effect of the lethal strain of Plasmodium yoelii 17XL.

Akimitsu N, Kim HS, Hamamoto H, Kamura K, Fukuma N, Arimitsu N, Ono K, Wataya Y, Torii M, Sekimizu K.

Parasitol Res. 2004 Aug;93(6):499-503. Epub 2004 Jul 24.

PMID:
15278442

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