Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 13

1.

HEx: A heterologous expression platform for the discovery of fungal natural products.

Harvey CJB, Tang M, Schlecht U, Horecka J, Fischer CR, Lin HC, Li J, Naughton B, Cherry J, Miranda M, Li YF, Chu AM, Hennessy JR, Vandova GA, Inglis D, Aiyar RS, Steinmetz LM, Davis RW, Medema MH, Sattely E, Khosla C, St Onge RP, Tang Y, Hillenmeyer ME.

Sci Adv. 2018 Apr 11;4(4):eaar5459. doi: 10.1126/sciadv.aar5459. eCollection 2018 Apr.

2.

A method for high-throughput production of sequence-verified DNA libraries and strain collections.

Smith JD, Schlecht U, Xu W, Suresh S, Horecka J, Proctor MJ, Aiyar RS, Bennett RA, Chu A, Li YF, Roy K, Davis RW, Steinmetz LM, Hyman RW, Levy SF, St Onge RP.

Mol Syst Biol. 2017 Feb 13;13(2):913. doi: 10.15252/msb.20167233.

3.

A privacy-preserving solution for compressed storage and selective retrieval of genomic data.

Huang Z, Ayday E, Lin H, Aiyar RS, Molyneaux A, Xu Z, Fellay J, Steinmetz LM, Hubaux JP.

Genome Res. 2016 Dec;26(12):1687-1696. Epub 2016 Oct 27.

4.

Comprehensive curation and analysis of fungal biosynthetic gene clusters of published natural products.

Li YF, Tsai KJS, Harvey CJB, Li JJ, Ary BE, Berlew EE, Boehman BL, Findley DM, Friant AG, Gardner CA, Gould MP, Ha JH, Lilley BK, McKinstry EL, Nawal S, Parry RC, Rothchild KW, Silbert SD, Tentilucci MD, Thurston AM, Wai RB, Yoon Y, Aiyar RS, Medema MH, Hillenmeyer ME, Charkoudian LK.

Fungal Genet Biol. 2016 Apr;89:18-28. doi: 10.1016/j.fgb.2016.01.012. Epub 2016 Jan 22.

5.

Yeast as a system for modeling mitochondrial disease mechanisms and discovering therapies.

Lasserre JP, Dautant A, Aiyar RS, Kucharczyk R, Glatigny A, Tribouillard-Tanvier D, Rytka J, Blondel M, Skoczen N, Reynier P, Pitayu L, Rötig A, Delahodde A, Steinmetz LM, Dujardin G, Procaccio V, di Rago JP.

Dis Model Mech. 2015 Jun;8(6):509-26. doi: 10.1242/dmm.020438. Review.

6.

Mitochondrial protein sorting as a therapeutic target for ATP synthase disorders.

Aiyar RS, Bohnert M, Duvezin-Caubet S, Voisset C, Gagneur J, Fritsch ES, Couplan E, von der Malsburg K, Funaya C, Soubigou F, Courtin F, Suresh S, Kucharczyk R, Evrard J, Antony C, St Onge RP, Blondel M, di Rago JP, van der Laan M, Steinmetz LM.

Nat Commun. 2014 Dec 18;5:5585. doi: 10.1038/ncomms6585.

7.

Alternative polyadenylation diversifies post-transcriptional regulation by selective RNA-protein interactions.

Gupta I, Clauder-Münster S, Klaus B, Järvelin AI, Aiyar RS, Benes V, Wilkening S, Huber W, Pelechano V, Steinmetz LM.

Mol Syst Biol. 2014 Feb 25;10:719. doi: 10.1002/msb.135068. Print 2014.

8.

An evaluation of high-throughput approaches to QTL mapping in Saccharomyces cerevisiae.

Wilkening S, Lin G, Fritsch ES, Tekkedil MM, Anders S, Kuehn R, Nguyen M, Aiyar RS, Proctor M, Sakhanenko NA, Galas DJ, Gagneur J, Deutschbauer A, Steinmetz LM.

Genetics. 2014 Mar;196(3):853-65. doi: 10.1534/genetics.113.160291. Epub 2013 Dec 27.

9.

Genotype-environment interactions reveal causal pathways that mediate genetic effects on phenotype.

Gagneur J, Stegle O, Zhu C, Jakob P, Tekkedil MM, Aiyar RS, Schuon AK, Pe'er D, Steinmetz LM.

PLoS Genet. 2013;9(9):e1003803. doi: 10.1371/journal.pgen.1003803. Epub 2013 Sep 19.

10.

The genomic and transcriptomic landscape of a HeLa cell line.

Landry JJ, Pyl PT, Rausch T, Zichner T, Tekkedil MM, Stütz AM, Jauch A, Aiyar RS, Pau G, Delhomme N, Gagneur J, Korbel JO, Huber W, Steinmetz LM.

G3 (Bethesda). 2013 Aug 7;3(8):1213-24. doi: 10.1534/g3.113.005777.

11.

Experimental relocation of the mitochondrial ATP9 gene to the nucleus reveals forces underlying mitochondrial genome evolution.

Bietenhader M, Martos A, Tetaud E, Aiyar RS, Sellem CH, Kucharczyk R, Clauder-Münster S, Giraud MF, Godard F, Salin B, Sagot I, Gagneur J, Déquard-Chablat M, Contamine V, Hermann-Le Denmat S, Sainsard-Chanet A, Steinmetz LM, di Rago JP.

PLoS Genet. 2012;8(8):e1002876. doi: 10.1371/journal.pgen.1002876. Epub 2012 Aug 16.

12.

A yeast-based assay identifies drugs active against human mitochondrial disorders.

Couplan E, Aiyar RS, Kucharczyk R, Kabala A, Ezkurdia N, Gagneur J, St Onge RP, Salin B, Soubigou F, Le Cann M, Steinmetz LM, di Rago JP, Blondel M.

Proc Natl Acad Sci U S A. 2011 Jul 19;108(29):11989-94. doi: 10.1073/pnas.1101478108. Epub 2011 Jun 29.

13.

Identification of mitochondrial disease genes through integrative analysis of multiple datasets.

Aiyar RS, Gagneur J, Steinmetz LM.

Methods. 2008 Dec;46(4):248-55. doi: 10.1016/j.ymeth.2008.10.002. Epub 2008 Oct 16.

Supplemental Content

Loading ...
Support Center