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Items: 1 to 50 of 58

1.

Sulfatide isoform pattern in cerebrospinal fluid discriminates progressive MS from relapsing-remitting MS.

Novakova L, Singh AK, Malmeström C, Zetterberg H, Ståhlman M, Axelsson M, Adiels M, Borén J, Lycke J, Cardell SL, Blomqvist M.

J Neurochem. 2018 Apr 20. doi: 10.1111/jnc.14452. [Epub ahead of print]

PMID:
29676479
2.

Resting heart rate in late adolescence and long term risk of cardiovascular disease in Swedish men.

Lindgren M, Robertson J, Adiels M, Schaufelberger M, Åberg M, Torén K, Waern M, Åberg ND, Rosengren A.

Int J Cardiol. 2018 May 15;259:109-115. doi: 10.1016/j.ijcard.2018.01.110.

3.

Primary aldosteronism and thyroid disorders in atrial fibrillation: A Swedish nationwide case-control study.

Mourtzinis G, Adamsson Eryd S, Rosengren A, Björck L, Adiels M, Johannsson G, Manhem K.

Eur J Prev Cardiol. 2018 Jan 1:2047487318759853. doi: 10.1177/2047487318759853. [Epub ahead of print]

PMID:
29473461
4.

An Integrated Understanding of the Rapid Metabolic Benefits of a Carbohydrate-Restricted Diet on Hepatic Steatosis in Humans.

Mardinoglu A, Wu H, Bjornson E, Zhang C, Hakkarainen A, Räsänen SM, Lee S, Mancina RM, Bergentall M, Pietiläinen KH, Söderlund S, Matikainen N, Ståhlman M, Bergh PO, Adiels M, Piening BD, Granér M, Lundbom N, Williams KJ, Romeo S, Nielsen J, Snyder M, Uhlén M, Bergström G, Perkins R, Marschall HU, Bäckhed F, Taskinen MR, Borén J.

Cell Metab. 2018 Mar 6;27(3):559-571.e5. doi: 10.1016/j.cmet.2018.01.005. Epub 2018 Feb 15.

PMID:
29456073
5.

BMI and Mortality in Patients With New-Onset Type 2 Diabetes: A Comparison With Age- and Sex-Matched Control Subjects From the General Population.

Edqvist J, Rawshani A, Adiels M, Björck L, Lind M, Svensson AM, Gudbjörnsdottir S, Sattar N, Rosengren A.

Diabetes Care. 2018 Mar;41(3):485-493. doi: 10.2337/dc17-1309. Epub 2018 Jan 3.

PMID:
29298801
6.

Young women, body size and risk of atrial fibrillation.

Persson CE, Adiels M, Björck L, Rosengren A.

Eur J Prev Cardiol. 2018 Jan;25(2):173-180. doi: 10.1177/2047487317740644. Epub 2017 Nov 2.

PMID:
29095053
7.

Deficiency in perilipin 5 reduces mitochondrial function and membrane depolarization in mouse hearts.

Andersson L, Drevinge C, Mardani I, Dalen KT, Ståhlman M, Klevstig M, Lundqvist A, Haugen F, Adiels M, Fogelstrand P, Asin-Cayuela J, Hultén LM, Levin M, Ehrenborg E, Lee YK, Kimmel AR, Borén J, Levin MC.

Int J Biochem Cell Biol. 2017 Oct;91(Pt A):9-13. doi: 10.1016/j.biocel.2017.07.021. Epub 2017 Aug 12.

PMID:
28811250
8.

Long-term trends in the prevalence of patients hospitalized with ischemic stroke from 1995 to 2010 in Sweden.

Giang KW, Mandalenakis Z, Nielsen S, Björck L, Lappas G, Adiels M, Jern C, Rosengren A.

PLoS One. 2017 Jun 16;12(6):e0179658. doi: 10.1371/journal.pone.0179658. eCollection 2017.

9.

Personal model-assisted identification of NAD+ and glutathione metabolism as intervention target in NAFLD.

Mardinoglu A, Bjornson E, Zhang C, Klevstig M, Söderlund S, Ståhlman M, Adiels M, Hakkarainen A, Lundbom N, Kilicarslan M, Hallström BM, Lundbom J, Vergès B, Barrett PH, Watts GF, Serlie MJ, Nielsen J, Uhlén M, Smith U, Marschall HU, Taskinen MR, Boren J.

Mol Syst Biol. 2017 Mar 2;13(3):916. doi: 10.15252/msb.20167422.

10.

Kinetics of plasma triglycerides in abdominal obesity.

Björnson E, Adiels M, Taskinen MR, Borén J.

Curr Opin Lipidol. 2017 Feb;28(1):11-18. doi: 10.1097/MOL.0000000000000375. Review.

PMID:
27898581
11.

An evaluation of the performance of SCORE Sweden 2015 in estimating cardiovascular risk: The Northern Sweden MONICA Study 1999-2014.

Karjalainen T, Adiels M, Björck L, Cooney MT, Graham I, Perk J, Rosengren A, Söderberg S, Eliasson M.

Eur J Prev Cardiol. 2017 Jan;24(1):103-110. Epub 2016 Oct 5.

PMID:
27708071
12.

Changes in Dietary Fat Intake and Projections for Coronary Heart Disease Mortality in Sweden: A Simulation Study.

Björck L, Rosengren A, Winkvist A, Capewell S, Adiels M, Bandosz P, Critchley J, Boman K, Guzman-Castillo M, O'Flaherty M, Johansson I.

PLoS One. 2016 Aug 4;11(8):e0160474. doi: 10.1371/journal.pone.0160474. eCollection 2016.

13.

Triglyceride-rich lipoprotein metabolism in women: roles of apoC-II and apoC-III.

Ooi EM, Chan DC, Hodson L, Adiels M, Boren J, Karpe F, Fielding BA, Watts GF, Barrett PH.

Eur J Clin Invest. 2016 Aug;46(8):730-6. doi: 10.1111/eci.12657.

PMID:
27378472
14.

Perilipin 5 is protective in the ischemic heart.

Drevinge C, Dalen KT, Mannila MN, Täng MS, Ståhlman M, Klevstig M, Lundqvist A, Mardani I, Haugen F, Fogelstrand P, Adiels M, Asin-Cayuela J, Ekestam C, Gådin JR, Lee YK, Nebb H, Svedlund S, Johansson BR, Hultén LM, Romeo S, Redfors B, Omerovic E, Levin M, Gan LM, Eriksson P, Andersson L, Ehrenborg E, Kimmel AR, Borén J, Levin MC.

Int J Cardiol. 2016 Sep 15;219:446-54. doi: 10.1016/j.ijcard.2016.06.037. Epub 2016 Jun 16.

15.

Metabolic transformations of dietary polyphenols: comparison between in vitro colonic and hepatic models and in vivo urinary metabolites.

Vetrani C, Rivellese AA, Annuzzi G, Adiels M, Borén J, Mattila I, Orešič M, Aura AM.

J Nutr Biochem. 2016 Jul;33:111-8. doi: 10.1016/j.jnutbio.2016.03.007. Epub 2016 Mar 29.

PMID:
27155917
16.

Targeting acid sphingomyelinase reduces cardiac ceramide accumulation in the post-ischemic heart.

Klevstig M, Ståhlman M, Lundqvist A, Scharin Täng M, Fogelstrand P, Adiels M, Andersson L, Kolesnick R, Jeppsson A, Borén J, Levin MC.

J Mol Cell Cardiol. 2016 Apr;93:69-72. doi: 10.1016/j.yjmcc.2016.02.019. Epub 2016 Feb 28.

17.

ApoA-II HDL Catabolism and Its Relationships With the Kinetics of ApoA-I HDL and of VLDL1, in Abdominal Obesity.

Vergès B, Adiels M, Boren J, Barrett PH, Watts GF, Chan D, Duvillard L, Söderlund S, Matikainen N, Kahri J, Lundbom N, Lundbom J, Hakkarainen A, Aho S, Simoneau-Robin I, Taskinen MR.

J Clin Endocrinol Metab. 2016 Apr;101(4):1398-406. doi: 10.1210/jc.2015-3740. Epub 2016 Feb 2.

PMID:
26835543
18.

Kinetic Studies to Elucidate Impaired Metabolism of Triglyceride-rich Lipoproteins in Humans.

Adiels M, Mardinoglu A, Taskinen MR, Borén J.

Front Physiol. 2015 Nov 20;6:342. doi: 10.3389/fphys.2015.00342. eCollection 2015. Review.

19.

Menopausal Status and Abdominal Obesity Are Significant Determinants of Hepatic Lipid Metabolism in Women.

Hodson L, Banerjee R, Rial B, Arlt W, Adiels M, Boren J, Marinou K, Fisher C, Mostad IL, Stratton IM, Barrett PH, Chan DC, Watts GF, Harnden K, Karpe F, Fielding BA.

J Am Heart Assoc. 2015 Oct 2;4(10):e002258. doi: 10.1161/JAHA.115.002258.

20.

Improved Estimation of Human Lipoprotein Kinetics with Mixed Effects Models.

Berglund M, Adiels M, Taskinen MR, Borén J, Wennberg B.

PLoS One. 2015 Sep 30;10(9):e0138538. doi: 10.1371/journal.pone.0138538. eCollection 2015.

21.

Model-Based Quantification of the Systemic Interplay between Glucose and Fatty Acids in the Postprandial State.

Sips FL, Nyman E, Adiels M, Hilbers PA, Strålfors P, van Riel NA, Cedersund G.

PLoS One. 2015 Sep 10;10(9):e0135665. doi: 10.1371/journal.pone.0135665. eCollection 2015.

22.

Kinetic and Related Determinants of Plasma Triglyceride Concentration in Abdominal Obesity: Multicenter Tracer Kinetic Study.

Borén J, Watts GF, Adiels M, Söderlund S, Chan DC, Hakkarainen A, Lundbom N, Matikainen N, Kahri J, Vergès B, Barrett PH, Taskinen MR.

Arterioscler Thromb Vasc Biol. 2015 Oct;35(10):2218-24. doi: 10.1161/ATVBAHA.115.305614. Epub 2015 Aug 27. Erratum in: Arterioscler Thromb Vasc Biol. 2015 Nov;35(11):e57.

23.

Prognostic Significance of Resting Heart Rate and Use of β-Blockers in Atrial Fibrillation and Sinus Rhythm in Patients With Heart Failure and Reduced Ejection Fraction: Findings From the Swedish Heart Failure Registry.

Li SJ, Sartipy U, Lund LH, Dahlström U, Adiels M, Petzold M, Fu M.

Circ Heart Fail. 2015 Sep;8(5):871-9. doi: 10.1161/CIRCHEARTFAILURE.115.002285. Epub 2015 Aug 4.

24.

Imaging of Intracellular and Extracellular ROS Levels in Atherosclerotic Mouse Aortas Ex Vivo: Effects of Lipid Lowering by Diet or Atorvastatin.

Ekstrand M, Gustafsson Trajkovska M, Perman-Sundelin J, Fogelstrand P, Adiels M, Johansson M, Mattsson-Hultén L, Borén J, Levin M.

PLoS One. 2015 Jun 22;10(6):e0130898. doi: 10.1371/journal.pone.0130898. eCollection 2015.

25.

Interrelationships between the kinetics of VLDL subspecies and HDL catabolism in abdominal obesity: a multicenter tracer kinetic study.

Vergès B, Adiels M, Boren J, Barrett PH, Watts GF, Chan D, Duvillard L, Söderlund S, Matikainen N, Kahri J, Robin I, Taskinen MR.

J Clin Endocrinol Metab. 2014 Nov;99(11):4281-90. doi: 10.1210/jc.2014-2365. Epub 2014 Jul 31.

PMID:
25077901
26.

Dietary medium chain fatty acid supplementation leads to reduced VLDL lipolysis and uptake rates in comparison to linoleic acid supplementation.

van Schalkwijk DB, Pasman WJ, Hendriks HF, Verheij ER, Rubingh CM, van Bochove K, Vaes WH, Adiels M, Freidig AP, de Graaf AA.

PLoS One. 2014 Jul 21;9(7):e100376. doi: 10.1371/journal.pone.0100376. eCollection 2014.

27.

Hepatic lipogenesis and a marker of hepatic lipid oxidation, predict postprandial responses of triglyceride-rich lipoproteins.

Matikainen N, Adiels M, Söderlund S, Stennabb S, Ahola T, Hakkarainen A, Borén J, Taskinen MR.

Obesity (Silver Spring). 2014 Aug;22(8):1854-9. doi: 10.1002/oby.20781. Epub 2014 May 28.

28.

Postprandial hypertriglyceridemia as a coronary risk factor.

Borén J, Matikainen N, Adiels M, Taskinen MR.

Clin Chim Acta. 2014 Apr 20;431:131-42. doi: 10.1016/j.cca.2014.01.015. Epub 2014 Feb 6. Review.

PMID:
24508990
29.

Genetic variation in SULF2 is associated with postprandial clearance of triglyceride-rich remnant particles and triglyceride levels in healthy subjects.

Matikainen N, Burza MA, Romeo S, Hakkarainen A, Adiels M, Folkersen L, Eriksson P, Lundbom N, Ehrenborg E, Orho-Melander M, Taskinen MR, Borén J.

PLoS One. 2013 Nov 20;8(11):e79473. doi: 10.1371/journal.pone.0079473. eCollection 2013.

30.

Dyslipidemia, but not hyperglycemia and insulin resistance, is associated with marked alterations in the HDL lipidome in type 2 diabetic subjects in the DIWA cohort: impact on small HDL particles.

Ståhlman M, Fagerberg B, Adiels M, Ekroos K, Chapman JM, Kontush A, Borén J.

Biochim Biophys Acta. 2013 Nov;1831(11):1609-17. doi: 10.1016/j.bbalip.2013.07.009. Epub 2013 Jul 27.

PMID:
23896361
31.

Cardiac steatosis associates with visceral obesity in nondiabetic obese men.

Granér M, Siren R, Nyman K, Lundbom J, Hakkarainen A, Pentikäinen MO, Lauerma K, Lundbom N, Adiels M, Nieminen MS, Taskinen MR.

J Clin Endocrinol Metab. 2013 Mar;98(3):1189-97. doi: 10.1210/jc.2012-3190. Epub 2013 Feb 15.

PMID:
23418318
32.

A continuous-time adaptive particle filter for estimations under measurement time uncertainties with an application to a plasma-leucine mixed effects model.

Krengel A, Hauth J, Taskinen MR, Adiels M, Jirstrand M.

BMC Syst Biol. 2013 Jan 19;7:8. doi: 10.1186/1752-0509-7-8.

33.

Patatin-like phospholipase domain-containing 3 (PNPLA3) I148M (rs738409) affects hepatic VLDL secretion in humans and in vitro.

Pirazzi C, Adiels M, Burza MA, Mancina RM, Levin M, Ståhlman M, Taskinen MR, Orho-Melander M, Perman J, Pujia A, Andersson L, Maglio C, Montalcini T, Wiklund O, Borén J, Romeo S.

J Hepatol. 2012 Dec;57(6):1276-82. doi: 10.1016/j.jhep.2012.07.030. Epub 2012 Aug 6.

PMID:
22878467
34.

Paradoxical lower serum triglyceride levels and higher type 2 diabetes mellitus susceptibility in obese individuals with the PNPLA3 148M variant.

Palmer CN, Maglio C, Pirazzi C, Burza MA, Adiels M, Burch L, Donnelly LA, Colhoun H, Doney AS, Dillon JF, Pearson ER, McCarthy M, Hattersley AT, Frayling T, Morris AD, Peltonen M, Svensson PA, Jacobson P, Borén J, Sjöström L, Carlsson LM, Romeo S.

PLoS One. 2012;7(6):e39362. doi: 10.1371/journal.pone.0039362. Epub 2012 Jun 18.

35.

PNPLA3 I148M (rs738409) genetic variant is associated with hepatocellular carcinoma in obese individuals.

Burza MA, Pirazzi C, Maglio C, Sjöholm K, Mancina RM, Svensson PA, Jacobson P, Adiels M, Baroni MG, Borén J, Ginanni Corradini S, Montalcini T, Sjöström L, Carlsson LM, Romeo S.

Dig Liver Dis. 2012 Dec;44(12):1037-41. doi: 10.1016/j.dld.2012.05.006. Epub 2012 Jun 15.

PMID:
22704398
36.

Interleukin 15 mediates joint destruction in Staphylococcus aureus arthritis.

Henningsson L, Jirholt P, Bogestål YR, Eneljung T, Adiels M, Lindholm C, McInnes I, Bulfone-Paus S, Lerner UH, Gjertsson I.

J Infect Dis. 2012 Sep 1;206(5):687-96. doi: 10.1093/infdis/jis295. Epub 2012 Apr 16.

PMID:
22508940
37.

Postprandial accumulation of chylomicrons and chylomicron remnants is determined by the clearance capacity.

Adiels M, Matikainen N, Westerbacka J, Söderlund S, Larsson T, Olofsson SO, Borén J, Taskinen MR.

Atherosclerosis. 2012 May;222(1):222-8. doi: 10.1016/j.atherosclerosis.2012.02.001. Epub 2012 Feb 7.

PMID:
22365426
38.

Clinical dyslipidaemia is associated with changes in the lipid composition and inflammatory properties of apolipoprotein-B-containing lipoproteins from women with type 2 diabetes.

Ståhlman M, Pham HT, Adiels M, Mitchell TW, Blanksby SJ, Fagerberg B, Ekroos K, Borén J.

Diabetologia. 2012 Apr;55(4):1156-66. doi: 10.1007/s00125-011-2444-6. Epub 2012 Jan 18.

PMID:
22252473
39.

Kinetic studies to investigate lipoprotein metabolism.

Borén J, Taskinen MR, Adiels M.

J Intern Med. 2012 Feb;271(2):166-73. doi: 10.1111/j.1365-2796.2011.02497.x. Review.

40.

Evaluation of macrophage-specific promoters using lentiviral delivery in mice.

Levin MC, Lidberg U, Jirholt P, Adiels M, Wramstedt A, Gustafsson K, Greaves DR, Li S, Fazio S, Linton MF, Olofsson SO, Borén J, Gjertsson I.

Gene Ther. 2012 Nov;19(11):1041-7. doi: 10.1038/gt.2011.195. Epub 2011 Dec 1.

41.

Investigations of a compartmental model for leucine kinetics using non-linear mixed effects models with ordinary and stochastic differential equations.

Berglund M, Sunnåker M, Adiels M, Jirstrand M, Wennberg B.

Math Med Biol. 2012 Dec;29(4):361-84. doi: 10.1093/imammb/dqr021. Epub 2011 Sep 30.

PMID:
21965323
42.

Dual metabolic defects are required to produce hypertriglyceridemia in obese subjects.

Taskinen MR, Adiels M, Westerbacka J, Söderlund S, Kahri J, Lundbom N, Lundbom J, Hakkarainen A, Olofsson SO, Orho-Melander M, Borén J.

Arterioscler Thromb Vasc Biol. 2011 Sep;31(9):2144-50. doi: 10.1161/ATVBAHA.111.224808. Epub 2011 Jul 21.

43.

Young women partition fatty acids towards ketone body production rather than VLDL-TAG synthesis, compared with young men.

Marinou K, Adiels M, Hodson L, Frayn KN, Karpe F, Fielding BA.

Br J Nutr. 2011 Mar;105(6):857-65. doi: 10.1017/S0007114510004472. Epub 2011 Jan 21.

PMID:
21251339
44.

Optimization of N-methyl-N-[tert-butyldimethylsilyl]trifluoroacetamide as a derivatization agent for determining isotopic enrichment of glycerol in very-low density lipoproteins.

Adiels M, Larsson T, Sutton P, Taskinen MR, Borén J, Fielding BA.

Rapid Commun Mass Spectrom. 2010 Mar 15;24(5):586-92. doi: 10.1002/rcm.4422.

PMID:
20140976
45.

[Recruitment of medical students to research requires early engagement. A research assistant program shows that early initiation yields better results].

Borén J, Adiels M, Wickström Y, Olofsson SO, Boström P.

Lakartidningen. 2009 Nov 11-17;106(46):3072-4. Swedish. No abstract available.

PMID:
19998609
46.

Nutritional systems biology modeling: from molecular mechanisms to physiology.

de Graaf AA, Freidig AP, De Roos B, Jamshidi N, Heinemann M, Rullmann JA, Hall KD, Adiels M, van Ommen B.

PLoS Comput Biol. 2009 Nov;5(11):e1000554. doi: 10.1371/journal.pcbi.1000554. Epub 2009 Nov 26. Review.

47.

ApoCIII-enriched LDL in type 2 diabetes displays altered lipid composition, increased susceptibility for sphingomyelinase, and increased binding to biglycan.

Hiukka A, Ståhlman M, Pettersson C, Levin M, Adiels M, Teneberg S, Leinonen ES, Hultén LM, Wiklund O, Oresic M, Olofsson SO, Taskinen MR, Ekroos K, Borén J.

Diabetes. 2009 Sep;58(9):2018-26. doi: 10.2337/db09-0206. Epub 2009 Jun 5.

48.

Overproduction of very low-density lipoproteins is the hallmark of the dyslipidemia in the metabolic syndrome.

Adiels M, Olofsson SO, Taskinen MR, Borén J.

Arterioscler Thromb Vasc Biol. 2008 Jul;28(7):1225-36. doi: 10.1161/ATVBAHA.107.160192. Review.

49.

Fatty liver, insulin resistance, and dyslipidemia.

Adiels M, Taskinen MR, Borén J.

Curr Diab Rep. 2008 Feb;8(1):60-4. Review.

PMID:
18367000
50.

Acute suppression of VLDL1 secretion rate by insulin is associated with hepatic fat content and insulin resistance.

Adiels M, Westerbacka J, Soro-Paavonen A, Häkkinen AM, Vehkavaara S, Caslake MJ, Packard C, Olofsson SO, Yki-Järvinen H, Taskinen MR, Borén J.

Diabetologia. 2007 Nov;50(11):2356-65. Epub 2007 Sep 12.

PMID:
17849096

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