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Processing of the Nedd2 precursor by ICE-like proteases and granzyme B.

Harvey NL, Trapani JA, Fernandes-Alnemri T, Litwack G, Alnemri ES, Kumar S.

Genes Cells. 1996 Jul;1(7):673-85.


The Ced-3/interleukin 1beta converting enzyme-like homolog Mch6 and the lamin-cleaving enzyme Mch2alpha are substrates for the apoptotic mediator CPP32.

Srinivasula SM, Fernandes-Alnemri T, Zangrilli J, Robertson N, Armstrong RC, Wang L, Trapani JA, Tomaselli KJ, Litwack G, Alnemri ES.

J Biol Chem. 1996 Oct 25;271(43):27099-106.


Activation of the CPP32 protease in apoptosis induced by 1-beta-D-arabinofuranosylcytosine and other DNA-damaging agents.

Datta R, Banach D, Kojima H, Talanian RV, Alnemri ES, Wong WW, Kufe DW.

Blood. 1996 Sep 15;88(6):1936-43.


In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains.

Fernandes-Alnemri T, Armstrong RC, Krebs J, Srinivasula SM, Wang L, Bullrich F, Fritz LC, Trapani JA, Tomaselli KJ, Litwack G, Alnemri ES.

Proc Natl Acad Sci U S A. 1996 Jul 23;93(15):7464-9.


FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex.

Muzio M, Chinnaiyan AM, Kischkel FC, O'Rourke K, Shevchenko A, Ni J, Scaffidi C, Bretz JD, Zhang M, Gentz R, Mann M, Krammer PH, Peter ME, Dixit VM.

Cell. 1996 Jun 14;85(6):817-27.


The CED-3/ICE-like protease Mch2 is activated during apoptosis and cleaves the death substrate lamin A.

Orth K, Chinnaiyan AM, Garg M, Froelich CJ, Dixit VM.

J Biol Chem. 1996 Jul 12;271(28):16443-6.


Fas-induced activation of the cell death-related protease CPP32 Is inhibited by Bcl-2 and by ICE family protease inhibitors.

Armstrong RC, Aja T, Xiang J, Gaur S, Krebs JF, Hoang K, Bai X, Korsmeyer SJ, Karanewsky DS, Fritz LC, Tomaselli KJ.

J Biol Chem. 1996 Jul 12;271(28):16850-5.


ICE family proteases: mediators of all apoptotic cell death?

Henkart PA.

Immunity. 1996 Mar;4(3):195-201. Review. No abstract available.


Molecular ordering of the cell death pathway. Bcl-2 and Bcl-xL function upstream of the CED-3-like apoptotic proteases.

Chinnaiyan AM, Orth K, O'Rourke K, Duan H, Poirier GG, Dixit VM.

J Biol Chem. 1996 Mar 1;271(9):4573-6.


Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis.

Enari M, Talanian RV, Wong WW, Nagata S.

Nature. 1996 Apr 25;380(6576):723-6.


Mch3, a novel human apoptotic cysteine protease highly related to CPP32.

Fernandes-Alnemri T, Takahashi A, Armstrong R, Krebs J, Fritz L, Tomaselli KJ, Wang L, Yu Z, Croce CM, Salveson G, et al.

Cancer Res. 1995 Dec 15;55(24):6045-52.


Prevention of vertebrate neuronal death by the crmA gene.

Gagliardini V, Fernandez PA, Lee RK, Drexler HC, Rotello RJ, Fishman MC, Yuan J.

Science. 1994 Feb 11;263(5148):826-8. Erratum in: Science 1994 Jun 3;264(5164):1388.


Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock.

Li P, Allen H, Banerjee S, Franklin S, Herzog L, Johnston C, McDowell J, Paskind M, Rodman L, Salfeld J, et al.

Cell. 1995 Feb 10;80(3):401-11.


Mch2, a new member of the apoptotic Ced-3/Ice cysteine protease gene family.

Fernandes-Alnemri T, Litwack G, Alnemri ES.

Cancer Res. 1995 Jul 1;55(13):2737-42.


Expression, refolding, and autocatalytic proteolytic processing of the interleukin-1 beta-converting enzyme precursor.

Ramage P, Cheneval D, Chvei M, Graff P, Hemmig R, Heng R, Kocher HP, Mackenzie A, Memmert K, Revesz L, et al.

J Biol Chem. 1995 Apr 21;270(16):9378-83.


Nuclear changes in apoptosis.

Earnshaw WC.

Curr Opin Cell Biol. 1995 Jun;7(3):337-43. Review.


Bcl-XL and Bcl-2 repress a common pathway of cell death.

Chao DT, Linette GP, Boise LH, White LS, Thompson CB, Korsmeyer SJ.

J Exp Med. 1995 Sep 1;182(3):821-8.


Protease activation during apoptosis: death by a thousand cuts?

Martin SJ, Green DR.

Cell. 1995 Aug 11;82(3):349-52. Review. No abstract available.


Requirement of an ICE/CED-3 protease for Fas/APO-1-mediated apoptosis.

Los M, Van de Craen M, Penning LC, Schenk H, Westendorp M, Baeuerle PA, Dröge W, Krammer PH, Fiers W, Schulze-Osthoff K.

Nature. 1995 May 4;375(6526):81-3.


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