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Items: 1 to 20 of 83

1.

Trapping of PARP1 and PARP2 by Clinical PARP Inhibitors.

Murai J, Huang SY, Das BB, Renaud A, Zhang Y, Doroshow JH, Ji J, Takeda S, Pommier Y.

Cancer Res. 2012 Nov 1;72(21):5588-99. doi: 10.1158/0008-5472.CAN-12-2753.

2.

N-methylpurine DNA glycosylase and OGG1 DNA repair activities: opposite associations with lung cancer risk.

Leitner-Dagan Y, Sevilya Z, Pinchev M, Kramer R, Elinger D, Roisman LC, Rennert HS, Schechtman E, Freedman L, Rennert G, Livneh Z, Paz-Elizur T.

J Natl Cancer Inst. 2012 Nov 21;104(22):1765-9. doi: 10.1093/jnci/djs445. Epub 2012 Oct 27.

3.

Inhibition of poly(ADP-ribose) polymerase inhibits ischemia/reperfusion induced neurodegeneration in retina via suppression of endoplasmic reticulum stress.

Li C, Wang L, Kern TS, Zheng L.

Biochem Biophys Res Commun. 2012 Jun 29;423(2):276-81. doi: 10.1016/j.bbrc.2012.05.109. Epub 2012 May 26.

PMID:
22640737
4.

Aberrant expression of N-methylpurine-DNA glycosylase influences patient survival in malignant gliomas.

Liu C, Tu Y, Yuan J, Mao X, He S, Wang L, Fu G, Zong J, Zhang Y.

J Biomed Biotechnol. 2012;2012:760679. doi: 10.1155/2012/760679. Epub 2012 Feb 27.

5.

Differential effects of poly(ADP-ribose) polymerase inhibition on DNA break repair in human cells are revealed with Epstein-Barr virus.

Ma W, Halweg CJ, Menendez D, Resnick MA.

Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):6590-5. doi: 10.1073/pnas.1118078109. Epub 2012 Apr 9.

6.

Y265C DNA polymerase beta knockin mice survive past birth and accumulate base excision repair intermediate substrates.

Senejani AG, Dalal S, Liu Y, Nottoli TP, McGrath JM, Clairmont CS, Sweasy JB.

Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):6632-7. doi: 10.1073/pnas.1200800109. Epub 2012 Apr 9.

7.

Elevated N3-methylpurine-DNA glycosylase DNA repair activity is associated with lung cancer.

Crosbie PA, Watson AJ, Agius R, Barber PV, Margison GP, Povey AC.

Mutat Res. 2012 Apr 1;732(1-2):43-6. doi: 10.1016/j.mrfmmm.2012.01.001. Epub 2012 Jan 14.

PMID:
22266085
8.

Increased PARP-1 association with DNA in alkylation damaged, PARP-inhibited mouse fibroblasts.

Kedar PS, Stefanick DF, Horton JK, Wilson SH.

Mol Cancer Res. 2012 Mar;10(3):360-8. doi: 10.1158/1541-7786.MCR-11-0477. Epub 2012 Jan 13.

9.

Balancing repair and tolerance of DNA damage caused by alkylating agents.

Fu D, Calvo JA, Samson LD.

Nat Rev Cancer. 2012 Jan 12;12(2):104-20. doi: 10.1038/nrc3185. Review.

10.

Alkylpurine-DNA-N-glycosylase confers resistance to temozolomide in xenograft models of glioblastoma multiforme and is associated with poor survival in patients.

Agnihotri S, Gajadhar AS, Ternamian C, Gorlia T, Diefes KL, Mischel PS, Kelly J, McGown G, Thorncroft M, Carlson BL, Sarkaria JN, Margison GP, Aldape K, Hawkins C, Hegi M, Guha A.

J Clin Invest. 2012 Jan;122(1):253-66. doi: 10.1172/JCI59334. Epub 2011 Dec 12. Erratum in: J Clin Invest. 2012 Feb 1;122(2):782.

11.

A subset of chronic lymphocytic leukemia patients display reduced levels of PARP1 expression coupled with a defective irradiation-induced apoptosis.

Bacalini MG, Tavolaro S, Peragine N, Marinelli M, Santangelo S, Del Giudice I, Mauro FR, Di Maio V, Ricciardi MR, Caiafa P, Chiaretti S, Foà R, Guarini A, Reale A.

Exp Hematol. 2012 Mar;40(3):197-206.e1. doi: 10.1016/j.exphem.2011.11.005. Epub 2011 Nov 23.

PMID:
22120020
12.

Direct repair of 3,N(4)-ethenocytosine by the human ALKBH2 dioxygenase is blocked by the AAG/MPG glycosylase.

Fu D, Samson LD.

DNA Repair (Amst). 2012 Jan 2;11(1):46-52. doi: 10.1016/j.dnarep.2011.10.004. Epub 2011 Nov 11.

13.

N-methylpurine DNA glycosylase and DNA polymerase beta modulate BER inhibitor potentiation of glioma cells to temozolomide.

Tang JB, Svilar D, Trivedi RN, Wang XH, Goellner EM, Moore B, Hamilton RL, Banze LA, Brown AR, Sobol RW.

Neuro Oncol. 2011 May;13(5):471-86. doi: 10.1093/neuonc/nor011. Epub 2011 Mar 3.

14.

Poly (ADP-ribose) polymerase (PARP) is not involved in base excision repair but PARP inhibition traps a single-strand intermediate.

Ström CE, Johansson F, Uhlén M, Szigyarto CA, Erixon K, Helleday T.

Nucleic Acids Res. 2011 Apr;39(8):3166-75. doi: 10.1093/nar/gkq1241. Epub 2010 Dec 22.

15.

PARP1 gene knock-out increases resistance to retinal degeneration without affecting retinal function.

Sahaboglu A, Tanimoto N, Kaur J, Sancho-Pelluz J, Huber G, Fahl E, Arango-Gonzalez B, Zrenner E, Ekström P, Löwenheim H, Seeliger M, Paquet-Durand F.

PLoS One. 2010 Nov 23;5(11):e15495. doi: 10.1371/journal.pone.0015495.

16.

Small molecule inhibitors of DNA repair nuclease activities of APE1.

Wilson DM 3rd, Simeonov A.

Cell Mol Life Sci. 2010 Nov;67(21):3621-31. doi: 10.1007/s00018-010-0488-2. Epub 2010 Aug 31. Review.

17.

Targeting poly(ADP-ribose) polymerase activity for cancer therapy.

Mégnin-Chanet F, Bollet MA, Hall J.

Cell Mol Life Sci. 2010 Nov;67(21):3649-62. doi: 10.1007/s00018-010-0490-8. Epub 2010 Aug 20. Review.

18.

PARP inhibition: PARP1 and beyond.

Rouleau M, Patel A, Hendzel MJ, Kaufmann SH, Poirier GG.

Nat Rev Cancer. 2010 Apr;10(4):293-301. doi: 10.1038/nrc2812. Epub 2010 Mar 4. Review.

19.

Mismatch repair deficient colorectal cancer in the era of personalized treatment.

Hewish M, Lord CJ, Martin SA, Cunningham D, Ashworth A.

Nat Rev Clin Oncol. 2010 Apr;7(4):197-208. doi: 10.1038/nrclinonc.2010.18. Epub 2010 Feb 23. Review.

PMID:
20177404
20.

Toward a unified nomenclature for mammalian ADP-ribosyltransferases.

Hottiger MO, Hassa PO, Lüscher B, Schüler H, Koch-Nolte F.

Trends Biochem Sci. 2010 Apr;35(4):208-19. doi: 10.1016/j.tibs.2009.12.003. Epub 2010 Jan 26. Review.

PMID:
20106667

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