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Items: 1 to 20 of 39

1.

Novel antibiotics targeting respiratory ATP synthesis in Gram-positive pathogenic bacteria.

Balemans W, Vranckx L, Lounis N, Pop O, Guillemont J, Vergauwen K, Mol S, Gilissen R, Motte M, Lançois D, De Bolle M, Bonroy K, Lill H, Andries K, Bald D, Koul A.

Antimicrob Agents Chemother. 2012 Aug;56(8):4131-9. doi: 10.1128/AAC.00273-12. Epub 2012 May 21.

2.

Understanding efflux in Gram-negative bacteria: opportunities for drug discovery.

Schweizer HP.

Expert Opin Drug Discov. 2012 Jul;7(7):633-42. doi: 10.1517/17460441.2012.688949. Epub 2012 May 19. Review.

PMID:
22607346
3.

Providing β-lactams a helping hand: targeting the AmpC β-lactamase induction pathway.

Mark BL, Vocadlo DJ, Oliver A.

Future Microbiol. 2011 Dec;6(12):1415-27. doi: 10.2217/fmb.11.128. Review. Erratum in: Future Microbiol. 2012 Feb;7(2):306.

PMID:
22122439
4.

Resistance emergence mechanism and mechanism of resistance suppression by tobramycin for cefepime for Pseudomonas aeruginosa.

Drusano GL, Bonomo RA, Bahniuk N, Bulitta JB, Vanscoy B, Defiglio H, Fikes S, Brown D, Drawz SM, Kulawy R, Louie A.

Antimicrob Agents Chemother. 2012 Jan;56(1):231-42. doi: 10.1128/AAC.05252-11. Epub 2011 Oct 17.

5.

Antagonistic interactions of Pseudomonas aeruginosa antibiotic resistance mechanisms in planktonic but not biofilm growth.

Mulet X, Moyá B, Juan C, Macià MD, Pérez JL, Blázquez J, Oliver A.

Antimicrob Agents Chemother. 2011 Oct;55(10):4560-8. doi: 10.1128/AAC.00519-11. Epub 2011 Aug 1.

6.

Bile salts induce resistance to polymyxin in enterohemorrhagic Escherichia coli O157:H7.

Kus JV, Gebremedhin A, Dang V, Tran SL, Serbanescu A, Barnett Foster D.

J Bacteriol. 2011 Sep;193(17):4509-15. doi: 10.1128/JB.00200-11. Epub 2011 Jul 1.

7.

Efflux pump inhibitors (EPIs) as new antimicrobial agents against Pseudomonas aeruginosa.

Askoura M, Mottawea W, Abujamel T, Taher I.

Libyan J Med. 2011 May 13;6. doi: 10.3402/ljm.v6i0.5870.

8.

Evaluation of multidrug efflux pump inhibitors by a new method using microfluidic channels.

Matsumoto Y, Hayama K, Sakakihara S, Nishino K, Noji H, Iino R, Yamaguchi A.

PLoS One. 2011 Apr 12;6(4):e18547. doi: 10.1371/journal.pone.0018547.

9.

Crystal structures of covalent complexes of β-lactam antibiotics with Escherichia coli penicillin-binding protein 5: toward an understanding of antibiotic specificity.

Nicola G, Tomberg J, Pratt RF, Nicholas RA, Davies C.

Biochemistry. 2010 Sep 21;49(37):8094-104. doi: 10.1021/bi100879m.

10.

Mutation of nfxB causes global changes in the physiology and metabolism of Pseudomonas aeruginosa.

Stickland HG, Davenport PW, Lilley KS, Griffin JL, Welch M.

J Proteome Res. 2010 Jun 4;9(6):2957-67. doi: 10.1021/pr9011415.

PMID:
20373734
11.

Antibacterial-resistant Pseudomonas aeruginosa: clinical impact and complex regulation of chromosomally encoded resistance mechanisms.

Lister PD, Wolter DJ, Hanson ND.

Clin Microbiol Rev. 2009 Oct;22(4):582-610. doi: 10.1128/CMR.00040-09. Review.

12.

Beta-lactam resistance response triggered by inactivation of a nonessential penicillin-binding protein.

Moya B, Dötsch A, Juan C, Blázquez J, Zamorano L, Haussler S, Oliver A.

PLoS Pathog. 2009 Mar;5(3):e1000353. doi: 10.1371/journal.ppat.1000353. Epub 2009 Mar 27.

13.

Inhibitors of multidrug resistant efflux systems in bacteria.

Zechini B, Versace I.

Recent Pat Antiinfect Drug Discov. 2009 Jan;4(1):37-50. Review.

PMID:
19149695
14.

Polymyxin B for the treatment of multidrug-resistant pathogens: a critical review.

Zavascki AP, Goldani LZ, Li J, Nation RL.

J Antimicrob Chemother. 2007 Dec;60(6):1206-15. Epub 2007 Sep 17. Review.

PMID:
17878146
15.

Antibiotic efflux pumps in Gram-negative bacteria: the inhibitor response strategy.

Mahamoud A, Chevalier J, Alibert-Franco S, Kern WV, Pagès JM.

J Antimicrob Chemother. 2007 Jun;59(6):1223-9. Epub 2007 Jan 17. Review.

PMID:
17229832
17.

Multidrug-resistance efflux pumps - not just for resistance.

Piddock LJ.

Nat Rev Microbiol. 2006 Aug;4(8):629-36. doi: 10.1038/nrmicro1464. Review.

PMID:
16845433
18.
19.

Practical applications and feasibility of efflux pump inhibitors in the clinic--a vision for applied use.

Lomovskaya O, Bostian KA.

Biochem Pharmacol. 2006 Mar 30;71(7):910-8. Epub 2006 Jan 19. Review.

PMID:
16427026
20.

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