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Items: 1 to 20 of 48


In silico structural, functional and pathogenicity evaluation of a novel mutation: an overview of HSD3B2 gene mutations.

Rabbani B, Mahdieh N, Haghi Ashtiani MT, Setoodeh A, Rabbani A.

Gene. 2012 Jul 25;503(2):215-21. doi: 10.1016/j.gene.2012.04.080. Epub 2012 May 8.


Class I histone deacetylases localize to the endoplasmic reticulum and modulate the unfolded protein response.

Kahali S, Sarcar B, Prabhu A, Seto E, Chinnaiyan P.

FASEB J. 2012 Jun;26(6):2437-45. doi: 10.1096/fj.11-193706. Epub 2012 Mar 2.


Dietary obesity-associated Hif1α activation in adipocytes restricts fatty acid oxidation and energy expenditure via suppression of the Sirt2-NAD+ system.

Krishnan J, Danzer C, Simka T, Ukropec J, Walter KM, Kumpf S, Mirtschink P, Ukropcova B, Gasperikova D, Pedrazzini T, Krek W.

Genes Dev. 2012 Feb 1;26(3):259-70. doi: 10.1101/gad.180406.111.


Ethanol affects differentiation-related pathways and suppresses Wnt signaling protein expression in human neural stem cells.

Vangipuram SD, Lyman WD.

Alcohol Clin Exp Res. 2012 May;36(5):788-97. doi: 10.1111/j.1530-0277.2011.01682.x. Epub 2011 Dec 7.


Endoplasmic reticulum stress inhibits STAT3-dependent suppression of hepatic gluconeogenesis via dephosphorylation and deacetylation.

Kimura K, Yamada T, Matsumoto M, Kido Y, Hosooka T, Asahara S, Matsuda T, Ota T, Watanabe H, Sai Y, Miyamoto K, Kaneko S, Kasuga M, Inoue H.

Diabetes. 2012 Jan;61(1):61-73. doi: 10.2337/db10-1684. Epub 2011 Nov 28.


Ethanol causes endoplasmic reticulum stress and impairment of insulin secretion in pancreatic β-cells.

Nguyen KH, Lee JH, Nyomba BL.

Alcohol. 2012 Feb;46(1):89-99. doi: 10.1016/j.alcohol.2011.04.001. Epub 2011 Aug 12.


Acetylation regulates gluconeogenesis by promoting PEPCK1 degradation via recruiting the UBR5 ubiquitin ligase.

Jiang W, Wang S, Xiao M, Lin Y, Zhou L, Lei Q, Xiong Y, Guan KL, Zhao S.

Mol Cell. 2011 Jul 8;43(1):33-44. doi: 10.1016/j.molcel.2011.04.028.


Structure-function analysis of the tertiary bile acid TUDCA for the resolution of endoplasmic reticulum stress in intestinal epithelial cells.

Berger E, Haller D.

Biochem Biophys Res Commun. 2011 Jun 17;409(4):610-5. doi: 10.1016/j.bbrc.2011.05.043. Epub 2011 May 14.


Ethanol induces endoplasmic reticulum stress in the developing brain.

Ke Z, Wang X, Liu Y, Fan Z, Chen G, Xu M, Bower KA, Frank JA, Li M, Fang S, Shi X, Luo J.

Alcohol Clin Exp Res. 2011 Sep;35(9):1574-83. doi: 10.1111/j.1530-0277.2011.01503.x. Epub 2011 May 20.


Class IIa histone deacetylases are hormone-activated regulators of FOXO and mammalian glucose homeostasis.

Mihaylova MM, Vasquez DS, Ravnskjaer K, Denechaud PD, Yu RT, Alvarez JG, Downes M, Evans RM, Montminy M, Shaw RJ.

Cell. 2011 May 13;145(4):607-21. doi: 10.1016/j.cell.2011.03.043.


Effects of alcohol on histone deacetylase 2 (HDAC2) and the neuroprotective role of trichostatin A (TSA).

Agudelo M, Gandhi N, Saiyed Z, Pichili V, Thangavel S, Khatavkar P, Yndart-Arias A, Nair M.

Alcohol Clin Exp Res. 2011 Aug;35(8):1550-6. doi: 10.1111/j.1530-0277.2011.01492.x. Epub 2011 Mar 29.


The role of oxidative stress in fetal alcohol spectrum disorders.

Brocardo PS, Gil-Mohapel J, Christie BR.

Brain Res Rev. 2011 Jun 24;67(1-2):209-25. doi: 10.1016/j.brainresrev.2011.02.001. Epub 2011 Apr 3. Review.


The emerging link between alcoholism risk and obesity in the United States.

Grucza RA, Krueger RF, Racette SB, Norberg KE, Hipp PR, Bierut LJ.

Arch Gen Psychiatry. 2010 Dec;67(12):1301-8. doi: 10.1001/archgenpsychiatry.2010.155.


NADPH oxidase links endoplasmic reticulum stress, oxidative stress, and PKR activation to induce apoptosis.

Li G, Scull C, Ozcan L, Tabas I.

J Cell Biol. 2010 Dec 13;191(6):1113-25. doi: 10.1083/jcb.201006121. Epub 2010 Dec 6.


The role of class I histone deacetylase (HDAC) on gluconeogenesis in liver.

Oiso H, Furukawa N, Suefuji M, Shimoda S, Ito A, Furumai R, Nakagawa J, Yoshida M, Nishino N, Araki E.

Biochem Biophys Res Commun. 2011 Jan 7;404(1):166-72. doi: 10.1016/j.bbrc.2010.11.086. Epub 2010 Nov 23.


Postnatal growth restriction and gene expression changes in a mouse model of fetal alcohol syndrome.

Kaminen-Ahola N, Ahola A, Flatscher-Bader T, Wilkins SJ, Anderson GJ, Whitelaw E, Chong S.

Birth Defects Res A Clin Mol Teratol. 2010 Oct;88(10):818-26. doi: 10.1002/bdra.20729.


Forkhead homeobox type O transcription factors in the responses to oxidative stress.

Storz P.

Antioxid Redox Signal. 2011 Feb 15;14(4):593-605. doi: 10.1089/ars.2010.3405. Epub 2010 Oct 19. Review.


Regulation of cellular metabolism by protein lysine acetylation.

Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.

Science. 2010 Feb 19;327(5968):1000-4. doi: 10.1126/science.1179689.


Prenatal alcohol exposure alters phosphorylation and glycosylation of proteins in rat offspring liver.

Fofana B, Yao XH, Rampitsch C, Cloutier S, Wilkins JA, Nyomba BL.

Proteomics. 2010 Feb;10(3):417-34. doi: 10.1002/pmic.200800969.


SIRT2 suppresses adipocyte differentiation by deacetylating FOXO1 and enhancing FOXO1's repressive interaction with PPARgamma.

Wang F, Tong Q.

Mol Biol Cell. 2009 Feb;20(3):801-8. doi: 10.1091/mbc.E08-06-0647. Epub 2008 Nov 26.

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