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Architecture and regulation of HtrA-family proteins involved in protein quality control and stress response.

Hansen G, Hilgenfeld R.

Cell Mol Life Sci. 2013 Mar;70(5):761-75. doi: 10.1007/s00018-012-1076-4. Epub 2012 Jul 18. Review.


SignalP 4.0: discriminating signal peptides from transmembrane regions.

Petersen TN, Brunak S, von Heijne G, Nielsen H.

Nat Methods. 2011 Sep 29;8(10):785-6. doi: 10.1038/nmeth.1701. No abstract available.


Molecular adaptation of the DegQ protease to exert protein quality control in the bacterial cell envelope.

Sawa J, Malet H, Krojer T, Canellas F, Ehrmann M, Clausen T.

J Biol Chem. 2011 Sep 2;286(35):30680-90. doi: 10.1074/jbc.M111.243832. Epub 2011 Jun 17.


The Legionella HtrA homologue DegQ is a self-compartmentizing protease that forms large 12-meric assemblies.

Wrase R, Scott H, Hilgenfeld R, Hansen G.

Proc Natl Acad Sci U S A. 2011 Jun 28;108(26):10490-5. doi: 10.1073/pnas.1101084108. Epub 2011 Jun 13.


The FALC-Loop web server for protein loop modeling.

Ko J, Lee D, Park H, Coutsias EA, Lee J, Seok C.

Nucleic Acids Res. 2011 Jul;39(Web Server issue):W210-4. doi: 10.1093/nar/gkr352. Epub 2011 May 16.


Protein loop modeling by using fragment assembly and analytical loop closure.

Lee J, Lee D, Park H, Coutsias EA, Seok C.

Proteins. 2010 Dec;78(16):3428-36. doi: 10.1002/prot.22849. Epub 2010 Sep 24.


HtrA proteases have a conserved activation mechanism that can be triggered by distinct molecular cues.

Krojer T, Sawa J, Huber R, Clausen T.

Nat Struct Mol Biol. 2010 Jul;17(7):844-52. doi: 10.1038/nsmb.1840. Epub 2010 Jun 27.


CPHmodels-3.0--remote homology modeling using structure-guided sequence profiles.

Nielsen M, Lundegaard C, Lund O, Petersen TN.

Nucleic Acids Res. 2010 Jul;38(Web Server issue):W576-81. doi: 10.1093/nar/gkq535. Epub 2010 Jun 11.


Salmonella enterica Serovar Typhimurium HtrA: regulation of expression and role of the chaperone and protease activities during infection.

Lewis C, Skovierova H, Rowley G, Rezuchova B, Homerova D, Stevenson A, Spencer J, Farn J, Kormanec J, Roberts M.

Microbiology. 2009 Mar;155(Pt 3):873-81. doi: 10.1099/mic.0.023754-0.


Unconventional serine proteases: variations on the catalytic Ser/His/Asp triad configuration.

Ekici OD, Paetzel M, Dalbey RE.

Protein Sci. 2008 Dec;17(12):2023-37. doi: 10.1110/ps.035436.108. Epub 2008 Sep 29. Review.


Characterization of DegQVh, a serine protease and a protective immunogen from a pathogenic Vibrio harveyi strain.

Zhang WW, Sun K, Cheng S, Sun L.

Appl Environ Microbiol. 2008 Oct;74(20):6254-62. doi: 10.1128/AEM.00109-08. Epub 2008 Aug 22.


Activation of DegP chaperone-protease via formation of large cage-like oligomers upon binding to substrate proteins.

Jiang J, Zhang X, Chen Y, Wu Y, Zhou ZH, Chang Z, Sui SF.

Proc Natl Acad Sci U S A. 2008 Aug 19;105(33):11939-44. doi: 10.1073/pnas.0805464105. Epub 2008 Aug 12.


Structural basis for the regulated protease and chaperone function of DegP.

Krojer T, Sawa J, Schäfer E, Saibil HR, Ehrmann M, Clausen T.

Nature. 2008 Jun 12;453(7197):885-90. doi: 10.1038/nature07004. Epub 2008 May 21.


On detection and assessment of statistical significance of Genomic Islands.

Chatterjee R, Chaudhuri K, Chaudhuri P.

BMC Genomics. 2008 Apr 1;9:150. doi: 10.1186/1471-2164-9-150.


Regulation of the sigmaE stress response by DegS: how the PDZ domain keeps the protease inactive in the resting state and allows integration of different OMP-derived stress signals upon folding stress.

Hasselblatt H, Kurzbauer R, Wilken C, Krojer T, Sawa J, Kurt J, Kirk R, Hasenbein S, Ehrmann M, Clausen T.

Genes Dev. 2007 Oct 15;21(20):2659-70.


Clustering and synaptic targeting of PICK1 requires direct interaction between the PDZ domain and lipid membranes.

Pan L, Wu H, Shen C, Shi Y, Jin W, Xia J, Zhang M.

EMBO J. 2007 Oct 31;26(21):4576-87. Epub 2007 Oct 4. Erratum in: EMBO J. 2009 Feb 4;28(3):307.


Prediction of protein subcellular localization.

Yu CS, Chen YC, Lu CH, Hwang JK.

Proteins. 2006 Aug 15;64(3):643-51.

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