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Items: 1 to 20 of 44

1.

Topical interleukin 1 receptor antagonist for treatment of dry eye disease: a randomized clinical trial.

Amparo F, Dastjerdi MH, Okanobo A, Ferrari G, Smaga L, Hamrah P, Jurkunas U, Schaumberg DA, Dana R.

JAMA Ophthalmol. 2013 Jun;131(6):715-23. doi: 10.1001/jamaophthalmol.2013.195.

2.

Efficacy of topical blockade of interleukin-1 in experimental dry eye disease.

Okanobo A, Chauhan SK, Dastjerdi MH, Kodati S, Dana R.

Am J Ophthalmol. 2012 Jul;154(1):63-71. doi: 10.1016/j.ajo.2012.01.034. Epub 2012 Apr 26.

3.

Structure of the activating IL-1 receptor signaling complex.

Thomas C, Bazan JF, Garcia KC.

Nat Struct Mol Biol. 2012 Mar 18;19(4):455-7. doi: 10.1038/nsmb.2260.

4.

β-Bulge triggers route-switching on the functional landscape of interleukin-1β.

Capraro DT, Roy M, Onuchic JN, Gosavi S, Jennings PA.

Proc Natl Acad Sci U S A. 2012 Jan 31;109(5):1490-3. doi: 10.1073/pnas.1114430109. Epub 2012 Jan 17.

5.

Dry eye disease: an immune-mediated ocular surface disorder.

Stevenson W, Chauhan SK, Dana R.

Arch Ophthalmol. 2012 Jan;130(1):90-100. doi: 10.1001/archophthalmol.2011.364. Review.

6.

Interleukin-1 in the pathogenesis and treatment of inflammatory diseases.

Dinarello CA.

Blood. 2011 Apr 7;117(14):3720-32. doi: 10.1182/blood-2010-07-273417. Epub 2011 Feb 8. Review.

7.

Accessory to inflammation.

Sims JE.

Nat Immunol. 2010 Oct;11(10):883-5. doi: 10.1038/ni1010-883. No abstract available.

PMID:
20856217
8.

Structural insights into the assembly and activation of IL-1β with its receptors.

Wang D, Zhang S, Li L, Liu X, Mei K, Wang X.

Nat Immunol. 2010 Oct;11(10):905-11. doi: 10.1038/ni.1925. Epub 2010 Aug 29.

PMID:
20802483
9.

Chronic blockade of interleukin-1 (IL-1) prevents and attenuates neuropathic pain behavior and spontaneous ectopic neuronal activity following nerve injury.

Gabay E, Wolf G, Shavit Y, Yirmiya R, Tal M.

Eur J Pain. 2011 Mar;15(3):242-8. doi: 10.1016/j.ejpain.2010.07.012. Epub 2010 Aug 30.

PMID:
20801063
10.

Interleukin-1 as a phenotypic immunomodulator in keratinizing squamous metaplasia of the ocular surface in Sjögren's syndrome.

Chen YT, Nikulina K, Lazarev S, Bahrami AF, Noble LB, Gallup M, McNamara NA.

Am J Pathol. 2010 Sep;177(3):1333-43. doi: 10.2353/ajpath.2010.100227. Epub 2010 Aug 9.

11.

Targeting IL-1beta in disease; the expanding role of NLRP3 inflammasome.

Mitroulis I, Skendros P, Ritis K.

Eur J Intern Med. 2010 Jun;21(3):157-63. doi: 10.1016/j.ejim.2010.03.005. Epub 2010 Mar 30. Review.

PMID:
20493414
12.

Autoimmunity at the ocular surface: pathogenesis and regulation.

Stern ME, Schaumburg CS, Dana R, Calonge M, Niederkorn JY, Pflugfelder SC.

Mucosal Immunol. 2010 Sep;3(5):425-42. doi: 10.1038/mi.2010.26. Epub 2010 May 19. Review.

13.

Features and development of Coot.

Emsley P, Lohkamp B, Scott WG, Cowtan K.

Acta Crystallogr D Biol Crystallogr. 2010 Apr;66(Pt 4):486-501. doi: 10.1107/S0907444910007493. Epub 2010 Mar 24.

14.

Denaturant-dependent conformational changes in a beta-trefoil protein: global and residue-specific aspects of an equilibrium denaturation process.

Latypov RF, Liu D, Jacob J, Harvey TS, Bondarenko PV, Kleemann GR, Brems DN, Raibekas AA.

Biochemistry. 2009 Nov 24;48(46):10934-47. doi: 10.1021/bi901570k.

PMID:
19839644
15.

Phaser crystallographic software.

McCoy AJ, Grosse-Kunstleve RW, Adams PD, Winn MD, Storoni LC, Read RJ.

J Appl Crystallogr. 2007 Aug 1;40(Pt 4):658-674. Epub 2007 Jul 13.

16.

Anakinra for rheumatoid arthritis: a systematic review.

Mertens M, Singh JA.

J Rheumatol. 2009 Jun;36(6):1118-25. doi: 10.3899/jrheum.090074. Epub 2009 May 15. Review.

PMID:
19447938
17.

Immunological and inflammatory functions of the interleukin-1 family.

Dinarello CA.

Annu Rev Immunol. 2009;27:519-50. doi: 10.1146/annurev.immunol.021908.132612. Review.

PMID:
19302047
18.

Inflammatory cytokine expression on the ocular surface in the Botulium toxin B induced murine dry eye model.

Zhu L, Shen J, Zhang C, Park CY, Kohanim S, Yew M, Parker JS, Chuck RS.

Mol Vis. 2009;15:250-8. Epub 2009 Jan 30.

19.

Nociceptors are interleukin-1beta sensors.

Binshtok AM, Wang H, Zimmermann K, Amaya F, Vardeh D, Shi L, Brenner GJ, Ji RR, Bean BP, Woolf CJ, Samad TA.

J Neurosci. 2008 Dec 24;28(52):14062-73. doi: 10.1523/JNEUROSCI.3795-08.2008.

20.

IL-23 promotes maintenance but not commitment to the Th17 lineage.

Stritesky GL, Yeh N, Kaplan MH.

J Immunol. 2008 Nov 1;181(9):5948-55.

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