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Antiinflammatory and chondroprotective effects of intraarticular injection of adipose-derived stem cells in experimental osteoarthritis.

ter Huurne M, Schelbergen R, Blattes R, Blom A, de Munter W, Grevers LC, Jeanson J, Noël D, Casteilla L, Jorgensen C, van den Berg W, van Lent PL.

Arthritis Rheum. 2012 Nov;64(11):3604-13. doi: 10.1002/art.34626.


Multipotent mesenchymal stromal cells and the innate immune system.

Le Blanc K, Mougiakakos D.

Nat Rev Immunol. 2012 Apr 25;12(5):383-96. doi: 10.1038/nri3209. Review.


Pre-culturing human adipose tissue mesenchymal stem cells under hypoxia increases their adipogenic and osteogenic differentiation potentials.

Valorani MG, Montelatici E, Germani A, Biddle A, D'Alessandro D, Strollo R, Patrizi MP, Lazzari L, Nye E, Otto WR, Pozzilli P, Alison MR.

Cell Prolif. 2012 Jun;45(3):225-38. doi: 10.1111/j.1365-2184.2012.00817.x.


Early-term effect of adult chondrocyte transplantation in an osteoarthritis animal model.

Desando G, Cavallo C, Tschon M, Giavaresi G, Martini L, Fini M, Giardino R, Facchini A, Grigolo B.

Tissue Eng Part A. 2012 Aug;18(15-16):1617-27. doi: 10.1089/ten.TEA.2011.0494. Epub 2012 Jun 25.


Concise review: Adipose-derived stem cells as a novel tool for future regenerative medicine.

Mizuno H, Tobita M, Uysal AC.

Stem Cells. 2012 May;30(5):804-10. doi: 10.1002/stem.1076. Review.


Osteoarthritis: a disease of the joint as an organ.

Loeser RF, Goldring SR, Scanzello CR, Goldring MB.

Arthritis Rheum. 2012 Jun;64(6):1697-707. doi: 10.1002/art.34453. Epub 2012 Mar 5. Review. No abstract available.


Platelet lysate from whole blood-derived pooled platelet concentrates and apheresis-derived platelet concentrates for the isolation and expansion of human bone marrow mesenchymal stromal cells: production process, content and identification of active components.

Fekete N, Gadelorge M, Fürst D, Maurer C, Dausend J, Fleury-Cappellesso S, Mailänder V, Lotfi R, Ignatius A, Sensebé L, Bourin P, Schrezenmeier H, Rojewski MT.

Cytotherapy. 2012 May;14(5):540-54. doi: 10.3109/14653249.2012.655420. Epub 2012 Feb 2.


SOX trio-co-transduced adipose stem cells in fibrin gel to enhance cartilage repair and delay the progression of osteoarthritis in the rat.

Lee JM, Im GI.

Biomaterials. 2012 Mar;33(7):2016-24. doi: 10.1016/j.biomaterials.2011.11.050. Epub 2011 Dec 19.


Homing and reparative effect of intra-articular injection of autologus mesenchymal stem cells in osteoarthritic animal model.

Mokbel AN, El Tookhy OS, Shamaa AA, Rashed LA, Sabry D, El Sayed AM.

BMC Musculoskelet Disord. 2011 Nov 15;12:259. doi: 10.1186/1471-2474-12-259.


Production of canine mesenchymal stem cells from adipose tissue and their application in dogs with chronic osteoarthritis of the humeroradial joints.

Guercio A, Di Marco P, Casella S, Cannella V, Russotto L, Purpari G, Di Bella S, Piccione G.

Cell Biol Int. 2012 Feb;36(2):189-94. doi: 10.1042/CBI20110304.


Roles of inflammatory and anabolic cytokines in cartilage metabolism: signals and multiple effectors converge upon MMP-13 regulation in osteoarthritis.

Goldring MB, Otero M, Plumb DA, Dragomir C, Favero M, El Hachem K, Hashimoto K, Roach HI, Olivotto E, Borzì RM, Marcu KB.

Eur Cell Mater. 2011 Feb 24;21:202-20.


Role of proinflammatory cytokines in the pathophysiology of osteoarthritis.

Kapoor M, Martel-Pelletier J, Lajeunesse D, Pelletier JP, Fahmi H.

Nat Rev Rheumatol. 2011 Jan;7(1):33-42. doi: 10.1038/nrrheum.2010.196. Epub 2010 Nov 30. Review.


The OARSI histopathology initiative - recommendations for histological assessments of osteoarthritis in the rabbit.

Laverty S, Girard CA, Williams JM, Hunziker EB, Pritzker KP.

Osteoarthritis Cartilage. 2010 Oct;18 Suppl 3:S53-65. doi: 10.1016/j.joca.2010.05.029.


Inflammatory conditions affect gene expression and function of human adipose tissue-derived mesenchymal stem cells.

Crop MJ, Baan CC, Korevaar SS, Ijzermans JN, Pescatori M, Stubbs AP, van Ijcken WF, Dahlke MH, Eggenhofer E, Weimar W, Hoogduijn MJ.

Clin Exp Immunol. 2010 Dec;162(3):474-86. doi: 10.1111/j.1365-2249.2010.04256.x. Epub 2010 Sep 15.


Treatment of osteoarthritis with infrapatellar fat pad derived mesenchymal stem cells in Rabbit.

Toghraie FS, Chenari N, Gholipour MA, Faghih Z, Torabinejad S, Dehghani S, Ghaderi A.

Knee. 2011 Mar;18(2):71-5. doi: 10.1016/j.knee.2010.03.001. Epub 2010 Jun 29.


Soluble factors from ASCs effectively direct control of chondrogenic fate.

Kim BS, Kang KS, Kang SK.

Cell Prolif. 2010 Jun;43(3):249-61. doi: 10.1111/j.1365-2184.2010.00680.x.


Mouse bone marrow-derived mesenchymal stromal cells turn activated macrophages into a regulatory-like profile.

Maggini J, Mirkin G, Bognanni I, Holmberg J, Piazzón IM, Nepomnaschy I, Costa H, Cañones C, Raiden S, Vermeulen M, Geffner JR.

PLoS One. 2010 Feb 16;5(2):e9252. doi: 10.1371/journal.pone.0009252.


The wound-healing and antioxidant effects of adipose-derived stem cells.

Kim WS, Park BS, Sung JH.

Expert Opin Biol Ther. 2009 Jul;9(7):879-87. doi: 10.1517/14712590903039684. Review.


Cartilage homeostasis in health and rheumatic diseases.

Goldring MB, Marcu KB.

Arthritis Res Ther. 2009;11(3):224. doi: 10.1186/ar2592. Epub 2009 May 19. Review.

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