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Items: 1 to 20 of 54

1.

Phosphorylation of Na-Cl cotransporter by OSR1 and SPAK kinases regulates its ubiquitination.

Hossain Khan MZ, Sohara E, Ohta A, Chiga M, Inoue Y, Isobe K, Wakabayashi M, Oi K, Rai T, Sasaki S, Uchida S.

Biochem Biophys Res Commun. 2012 Aug 24;425(2):456-61. doi: 10.1016/j.bbrc.2012.07.124. Epub 2012 Jul 27.

PMID:
22846565
2.

Salt-induced hypertension in a mouse model of Liddle syndrome is mediated by epithelial sodium channels in the brain.

Van Huysse JW, Amin MS, Yang B, Leenen FH.

Hypertension. 2012 Sep;60(3):691-6. doi: 10.1161/HYPERTENSIONAHA.112.193045. Epub 2012 Jul 16.

3.

KLHL3 mutations cause familial hyperkalemic hypertension by impairing ion transport in the distal nephron.

Louis-Dit-Picard H, Barc J, Trujillano D, Miserey-Lenkei S, Bouatia-Naji N, Pylypenko O, Beaurain G, Bonnefond A, Sand O, Simian C, Vidal-Petiot E, Soukaseum C, Mandet C, Broux F, Chabre O, Delahousse M, Esnault V, Fiquet B, Houillier P, Bagnis CI, Koenig J, Konrad M, Landais P, Mourani C, Niaudet P, Probst V, Thauvin C, Unwin RJ, Soroka SD, Ehret G, Ossowski S, Caulfield M; International Consortium for Blood Pressure (ICBP), Bruneval P, Estivill X, Froguel P, Hadchouel J, Schott JJ, Jeunemaitre X.

Nat Genet. 2012 Mar 11;44(4):456-60, S1-3. doi: 10.1038/ng.2218. Erratum in: Nat Genet. 2012;44(5):609.

PMID:
22406640
4.

Inducible kidney-specific Sgk1 knockout mice show a salt-losing phenotype.

Faresse N, Lagnaz D, Debonneville A, Ismailji A, Maillard M, Fejes-Toth G, Náray-Fejes-Tóth A, Staub O.

Am J Physiol Renal Physiol. 2012 Apr 15;302(8):F977-85. doi: 10.1152/ajprenal.00535.2011. Epub 2012 Feb 1.

5.

Mutations in kelch-like 3 and cullin 3 cause hypertension and electrolyte abnormalities.

Boyden LM, Choi M, Choate KA, Nelson-Williams CJ, Farhi A, Toka HR, Tikhonova IR, Bjornson R, Mane SM, Colussi G, Lebel M, Gordon RD, Semmekrot BA, Poujol A, Välimäki MJ, De Ferrari ME, Sanjad SA, Gutkin M, Karet FE, Tucci JR, Stockigt JR, Keppler-Noreuil KM, Porter CC, Anand SK, Whiteford ML, Davis ID, Dewar SB, Bettinelli A, Fadrowski JJ, Belsha CW, Hunley TE, Nelson RD, Trachtman H, Cole TR, Pinsk M, Bockenhauer D, Shenoy M, Vaidyanathan P, Foreman JW, Rasoulpour M, Thameem F, Al-Shahrouri HZ, Radhakrishnan J, Gharavi AG, Goilav B, Lifton RP.

Nature. 2012 Jan 22;482(7383):98-102. doi: 10.1038/nature10814.

6.

Is oxidative stress, a link between nephrolithiasis and obesity, hypertension, diabetes, chronic kidney disease, metabolic syndrome?

Khan SR.

Urol Res. 2012 Apr;40(2):95-112. doi: 10.1007/s00240-011-0448-9. Epub 2012 Jan 4. Review.

7.

Overexpression of the sodium chloride cotransporter is not sufficient to cause familial hyperkalemic hypertension.

McCormick JA, Nelson JH, Yang CL, Curry JN, Ellison DH.

Hypertension. 2011 Nov;58(5):888-94. doi: 10.1161/HYPERTENSIONAHA.110.167809. Epub 2011 Sep 6.

8.

Nedd4-2 modulates renal Na+-Cl- cotransporter via the aldosterone-SGK1-Nedd4-2 pathway.

Arroyo JP, Lagnaz D, Ronzaud C, Vázquez N, Ko BS, Moddes L, Ruffieux-Daidié D, Hausel P, Koesters R, Yang B, Stokes JB, Hoover RS, Gamba G, Staub O.

J Am Soc Nephrol. 2011 Sep;22(9):1707-19. doi: 10.1681/ASN.2011020132. Epub 2011 Aug 18.

9.

Update on nephrolithiasis: beyond symptomatic urinary tract obstruction.

Cupisti A.

J Nephrol. 2011 May-Jun;24 Suppl 18:S25-9. doi: 10.5301/JN.2011.7766. Review.

PMID:
21623579
10.

Respiratory distress and perinatal lethality in Nedd4-2-deficient mice.

Boase NA, Rychkov GY, Townley SL, Dinudom A, Candi E, Voss AK, Tsoutsman T, Semsarian C, Melino G, Koentgen F, Cook DI, Kumar S.

Nat Commun. 2011;2:287. doi: 10.1038/ncomms1284.

11.

Sodium and potassium balance depends on αENaC expression in connecting tubule.

Christensen BM, Perrier R, Wang Q, Zuber AM, Maillard M, Mordasini D, Malsure S, Ronzaud C, Stehle JC, Rossier BC, Hummler E.

J Am Soc Nephrol. 2010 Nov;21(11):1942-51. doi: 10.1681/ASN.2009101077. Epub 2010 Oct 14.

12.

Decreased ENaC expression compensates the increased NCC activity following inactivation of the kidney-specific isoform of WNK1 and prevents hypertension.

Hadchouel J, Soukaseum C, Büsst C, Zhou XO, Baudrie V, Zürrer T, Cambillau M, Elghozi JL, Lifton RP, Loffing J, Jeunemaitre X.

Proc Natl Acad Sci U S A. 2010 Oct 19;107(42):18109-14. doi: 10.1073/pnas.1006128107. Epub 2010 Oct 4.

13.

The evidence-based use of thiazide diuretics in hypertension and nephrolithiasis.

Reilly RF, Peixoto AJ, Desir GV.

Clin J Am Soc Nephrol. 2010 Oct;5(10):1893-903. doi: 10.2215/CJN.04670510. Epub 2010 Aug 26. Review.

14.

Role of the WNK-activated SPAK kinase in regulating blood pressure.

Rafiqi FH, Zuber AM, Glover M, Richardson C, Fleming S, Jovanović S, Jovanović A, O'Shaughnessy KM, Alessi DR.

EMBO Mol Med. 2010 Feb;2(2):63-75. doi: 10.1002/emmm.200900058.

15.

POSH stimulates the ubiquitination and the clathrin-independent endocytosis of ROMK1 channels.

Lin DH, Yue P, Pan CY, Sun P, Zhang X, Han Z, Roos M, Caplan M, Giebisch G, Wang WH.

J Biol Chem. 2009 Oct 23;284(43):29614-24. doi: 10.1074/jbc.M109.041582. Epub 2009 Aug 26.

16.

Activation of the epithelial sodium channel (ENaC) by serine proteases.

Rossier BC, Stutts MJ.

Annu Rev Physiol. 2009;71:361-79. doi: 10.1146/annurev.physiol.010908.163108. Review.

PMID:
18928407
17.

An efficient and versatile system for acute and chronic modulation of renal tubular function in transgenic mice.

Traykova-Brauch M, Schönig K, Greiner O, Miloud T, Jauch A, Bode M, Felsher DW, Glick AB, Kwiatkowski DJ, Bujard H, Horst J, von Knebel Doeberitz M, Niggli FK, Kriz W, Gröne HJ, Koesters R.

Nat Med. 2008 Sep;14(9):979-84. doi: 10.1038/nm.1865.

18.

Deubiquitylation regulates activation and proteolytic cleavage of ENaC.

Ruffieux-Daidié D, Poirot O, Boulkroun S, Verrey F, Kellenberger S, Staub O.

J Am Soc Nephrol. 2008 Nov;19(11):2170-80. doi: 10.1681/ASN.2007101130. Epub 2008 Aug 13.

19.

Salt-sensitive hypertension and cardiac hypertrophy in mice deficient in the ubiquitin ligase Nedd4-2.

Shi PP, Cao XR, Sweezer EM, Kinney TS, Williams NR, Husted RF, Nair R, Weiss RM, Williamson RA, Sigmund CD, Snyder PM, Staub O, Stokes JB, Yang B.

Am J Physiol Renal Physiol. 2008 Aug;295(2):F462-70. doi: 10.1152/ajprenal.90300.2008. Epub 2008 Jun 4.

20.

Mouse model of type II Bartter's syndrome. II. Altered expression of renal sodium- and water-transporting proteins.

Wagner CA, Loffing-Cueni D, Yan Q, Schulz N, Fakitsas P, Carrel M, Wang T, Verrey F, Geibel JP, Giebisch G, Hebert SC, Loffing J.

Am J Physiol Renal Physiol. 2008 Jun;294(6):F1373-80. doi: 10.1152/ajprenal.00613.2007. Epub 2008 Mar 5.

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