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dsRNA sensors and plasmacytoid dendritic cells in host defense and autoimmunity.

Wang Y, Swiecki M, McCartney SA, Colonna M.

Immunol Rev. 2011 Sep;243(1):74-90. doi: 10.1111/j.1600-065X.2011.01049.x. Review.


Innate sensing of HIV-infected cells.

Lepelley A, Louis S, Sourisseau M, Law HK, Pothlichet J, Schilte C, Chaperot L, Plumas J, Randall RE, Si-Tahar M, Mammano F, Albert ML, Schwartz O.

PLoS Pathog. 2011 Feb;7(2):e1001284. doi: 10.1371/journal.ppat.1001284. Epub 2011 Feb 17.


Challenges in infant immunity: implications for responses to infection and vaccines.

PrabhuDas M, Adkins B, Gans H, King C, Levy O, Ramilo O, Siegrist CA.

Nat Immunol. 2011 Mar;12(3):189-94. doi: 10.1038/ni0311-189. No abstract available.


Ontogeny of Toll-like receptor mediated cytokine responses of human blood mononuclear cells.

Corbett NP, Blimkie D, Ho KC, Cai B, Sutherland DP, Kallos A, Crabtree J, Rein-Weston A, Lavoie PM, Turvey SE, Hawkins NR, Self SG, Wilson CB, Hajjar AM, Fortuno ES 3rd, Kollmann TR.

PLoS One. 2010 Nov 30;5(11):e15041. doi: 10.1371/journal.pone.0015041.


Acquisition of adult-like TLR4 and TLR9 responses during the first year of life.

Nguyen M, Leuridan E, Zhang T, De Wit D, Willems F, Van Damme P, Goldman M, Goriely S.

PLoS One. 2010 Apr 28;5(4):e10407. doi: 10.1371/journal.pone.0010407.


Systematic cytokine receptor profiling reveals GM-CSF as a novel TLR-independent activator of human plasmacytoid predendritic cells.

Ghirelli C, Zollinger R, Soumelis V.

Blood. 2010 Jun 17;115(24):5037-40. doi: 10.1182/blood-2010-01-266932. Epub 2010 Apr 9.


Neonatal innate TLR-mediated responses are distinct from those of adults.

Kollmann TR, Crabtree J, Rein-Weston A, Blimkie D, Thommai F, Wang XY, Lavoie PM, Furlong J, Fortuno ES 3rd, Hajjar AM, Hawkins NR, Self SG, Wilson CB.

J Immunol. 2009 Dec 1;183(11):7150-60. doi: 10.4049/jimmunol.0901481. Epub 2009 Nov 16.


IL-12 and type I IFN response of neonatal myeloid DC to human CMV infection.

Renneson J, Dutta B, Goriely S, Danis B, Lecomte S, Laes JF, Tabi Z, Goldman M, Marchant A.

Eur J Immunol. 2009 Oct;39(10):2789-99. doi: 10.1002/eji.200939414.


CD2 distinguishes two subsets of human plasmacytoid dendritic cells with distinct phenotype and functions.

Matsui T, Connolly JE, Michnevitz M, Chaussabel D, Yu CI, Glaser C, Tindle S, Pypaert M, Freitas H, Piqueras B, Banchereau J, Palucka AK.

J Immunol. 2009 Jun 1;182(11):6815-23. doi: 10.4049/jimmunol.0802008.


Differential regulation of interleukin 12 and interleukin 23 production in human dendritic cells.

Gerosa F, Baldani-Guerra B, Lyakh LA, Batoni G, Esin S, Winkler-Pickett RT, Consolaro MR, De Marchi M, Giachino D, Robbiano A, Astegiano M, Sambataro A, Kastelein RA, Carra G, Trinchieri G.

J Exp Med. 2008 Jun 9;205(6):1447-61. doi: 10.1084/jem.20071450. Epub 2008 May 19.


Interferon regulatory factor 7-mediated responses are defective in cord blood plasmacytoid dendritic cells.

Danis B, George TC, Goriely S, Dutta B, Renneson J, Gatto L, Fitzgerald-Bocarsly P, Marchant A, Goldman M, Willems F, De Wit D.

Eur J Immunol. 2008 Feb;38(2):507-17. doi: 10.1002/eji.200737760.


Type I interferons protect neonates from acute inflammation through interleukin 10-producing B cells.

Zhang X, Deriaud E, Jiao X, Braun D, Leclerc C, Lo-Man R.

J Exp Med. 2007 May 14;204(5):1107-18. Epub 2007 May 7.


The adenosine system selectively inhibits TLR-mediated TNF-alpha production in the human newborn.

Levy O, Coughlin M, Cronstein BN, Roy RM, Desai A, Wessels MR.

J Immunol. 2006 Aug 1;177(3):1956-66.


Cutting edge: IFN-gamma regulates the induction and expansion of IL-17-producing CD4 T cells during mycobacterial infection.

Cruz A, Khader SA, Torrado E, Fraga A, Pearl JE, Pedrosa J, Cooper AM, Castro AG.

J Immunol. 2006 Aug 1;177(3):1416-20.


Interleukin 12p40 is required for dendritic cell migration and T cell priming after Mycobacterium tuberculosis infection.

Khader SA, Partida-Sanchez S, Bell G, Jelley-Gibbs DM, Swain S, Pearl JE, Ghilardi N, Desauvage FJ, Lund FE, Cooper AM.

J Exp Med. 2006 Jul 10;203(7):1805-15. Epub 2006 Jul 3.


Purified neonatal plasmacytoid dendritic cells overcome intrinsic maturation defect with TLR agonist stimulation.

Gold MC, Donnelly E, Cook MS, Leclair CM, Lewinsohn DA.

Pediatr Res. 2006 Jul;60(1):34-7. Epub 2006 May 11.


Specialization, kinetics, and repertoire of type 1 interferon responses by human plasmacytoid predendritic cells.

Ito T, Kanzler H, Duramad O, Cao W, Liu YJ.

Blood. 2006 Mar 15;107(6):2423-31. Epub 2005 Nov 17.


Upon TLR9 signaling, CD5+ B cells control the IL-12-dependent Th1-priming capacity of neonatal DCs.

Sun CM, Deriaud E, Leclerc C, Lo-Man R.

Immunity. 2005 Apr;22(4):467-77.


Neonatal adaptive immunity comes of age.

Adkins B, Leclerc C, Marshall-Clarke S.

Nat Rev Immunol. 2004 Jul;4(7):553-64. doi: 10.1038/nri1394. Review. No abstract available.


A defect in nucleosome remodeling prevents IL-12(p35) gene transcription in neonatal dendritic cells.

Goriely S, Van Lint C, Dadkhah R, Libin M, De Wit D, Demonté D, Willems F, Goldman M.

J Exp Med. 2004 Apr 5;199(7):1011-6. Epub 2004 Mar 29.

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