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Items: 1 to 20 of 73


Effects of phosphate binders in moderate CKD.

Block GA, Wheeler DC, Persky MS, Kestenbaum B, Ketteler M, Spiegel DM, Allison MA, Asplin J, Smits G, Hoofnagle AN, Kooienga L, Thadhani R, Mannstadt M, Wolf M, Chertow GM.

J Am Soc Nephrol. 2012 Aug;23(8):1407-15. doi: 10.1681/ASN.2012030223.


Smooth muscle cell-specific runx2 deficiency inhibits vascular calcification.

Sun Y, Byon CH, Yuan K, Chen J, Mao X, Heath JM, Javed A, Zhang K, Anderson PG, Chen Y.

Circ Res. 2012 Aug 17;111(5):543-52. doi: 10.1161/CIRCRESAHA.112.267237.


MicroRNAs that target Ca(2+) transporters are involved in vascular smooth muscle cell calcification.

Gui T, Zhou G, Sun Y, Shimokado A, Itoh S, Oikawa K, Muragaki Y.

Lab Invest. 2012 Sep;92(9):1250-9. doi: 10.1038/labinvest.2012.85.


Vascular Klotho deficiency potentiates the development of human artery calcification and mediates resistance to fibroblast growth factor 23.

Lim K, Lu TS, Molostvov G, Lee C, Lam FT, Zehnder D, Hsiao LL.

Circulation. 2012 May 8;125(18):2243-55. doi: 10.1161/CIRCULATIONAHA.111.053405.


Vitamin D receptor activators inhibit vascular smooth muscle cell mineralization induced by phosphate and TNF-α.

Aoshima Y, Mizobuchi M, Ogata H, Kumata C, Nakazawa A, Kondo F, Ono N, Koiwa F, Kinugasa E, Akizawa T.

Nephrol Dial Transplant. 2012 May;27(5):1800-6. doi: 10.1093/ndt/gfr758.


Stanniocalcin 2 is associated with ectopic calcification in α-klotho mutant mice and inhibits hyperphosphatemia-induced calcification in aortic vascular smooth muscle cells.

Takei Y, Yamamoto H, Sato T, Otani A, Kozai M, Masuda M, Taketani Y, Muto-Sato K, Lanske B, Takeda E.

Bone. 2012 Apr;50(4):998-1005. doi: 10.1016/j.bone.2012.01.006.


Sgk1 sensitivity of Na(+)/H(+) exchanger activity and cardiac remodeling following pressure overload.

Voelkl J, Lin Y, Alesutan I, Ahmed MS, Pasham V, Mia S, Gu S, Feger M, Saxena A, Metzler B, Kuhl D, Pichler BJ, Lang F.

Basic Res Cardiol. 2012 Mar;107(2):236. doi: 10.1007/s00395-011-0236-2.


Endogenous aldosterone is involved in vascular calcification in rat.

Wu SY, Yu YR, Cai Y, Jia LX, Wang X, Xiao CS, Tang CS, Qi YF.

Exp Biol Med (Maywood). 2012 Jan;237(1):31-7. doi: 10.1258/ebm.2011.011175.


The role of phosphorus in the development and progression of vascular calcification.

Kendrick J, Chonchol M.

Am J Kidney Dis. 2011 Nov;58(5):826-34. doi: 10.1053/j.ajkd.2011.07.020. Review.


The safety and tolerability of spironolactone in patients with mild to moderate chronic kidney disease.

Edwards NC, Steeds RP, Chue CD, Stewart PM, Ferro CJ, Townend JN.

Br J Clin Pharmacol. 2012 Mar;73(3):447-54. doi: 10.1111/j.1365-2125.2011.04102.x.


Cross talk between the renin-angiotensin-aldosterone system and vitamin D-FGF-23-klotho in chronic kidney disease.

de Borst MH, Vervloet MG, ter Wee PM, Navis G.

J Am Soc Nephrol. 2011 Sep;22(9):1603-9. doi: 10.1681/ASN.2010121251.


Downregulation of Klotho expression by dehydration.

Tang C, Pathare G, Michael D, Fajol A, Eichenmüller M, Lang F.

Am J Physiol Renal Physiol. 2011 Oct;301(4):F745-50. doi: 10.1152/ajprenal.00037.2011.


Mineralocorticoid receptors in vascular function and disease.

McCurley A, Jaffe IZ.

Mol Cell Endocrinol. 2012 Mar 24;350(2):256-65. doi: 10.1016/j.mce.2011.06.014. Review.


Klotho and the aging process.

Kuro-o M.

Korean J Intern Med. 2011 Jun;26(2):113-22. doi: 10.3904/kjim.2011.26.2.113. Review.


Eplerenone reverses spironolactone-induced painful gynaecomastia in cirrhotics.

Dimitriadis G, Papadopoulos V, Mimidis K.

Hepatol Int. 2011 Jun;5(2):738-9. doi: 10.1007/s12072-010-9235-x.


Phosphate and Klotho.

Kuro-O M.

Kidney Int Suppl. 2011 Apr;(121):S20-3. doi: 10.1038/ki.2011.26. Review.


Klotho deficiency causes vascular calcification in chronic kidney disease.

Hu MC, Shi M, Zhang J, Quiñones H, Griffith C, Kuro-o M, Moe OW.

J Am Soc Nephrol. 2011 Jan;22(1):124-36. doi: 10.1681/ASN.2009121311.


Hyperaldosteronism in Klotho-deficient mice.

Fischer SS, Kempe DS, Leibrock CB, Rexhepaj R, Siraskar B, Boini KM, Ackermann TF, Föller M, Hocher B, Rosenblatt KP, Kuro-O M, Lang F.

Am J Physiol Renal Physiol. 2010 Nov;299(5):F1171-7. doi: 10.1152/ajprenal.00233.2010.


Calcific uremic arteriolopathy: pathophysiology, reactive oxygen species and therapeutic approaches.

Sowers KM, Hayden MR.

Oxid Med Cell Longev. 2010 Mar-Apr;3(2):109-21. doi: 10.4161/oxim.3.2.11354. Review.


Androgen receptor-dependent transactivation of growth arrest-specific gene 6 mediates inhibitory effects of testosterone on vascular calcification.

Son BK, Akishita M, Iijima K, Ogawa S, Maemura K, Yu J, Takeyama K, Kato S, Eto M, Ouchi Y.

J Biol Chem. 2010 Mar 5;285(10):7537-44. doi: 10.1074/jbc.M109.055087.

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