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Items: 1 to 20 of 55

1.

BDNF and glucocorticoids regulate corticotrophin-releasing hormone (CRH) homeostasis in the hypothalamus.

Jeanneteau FD, Lambert WM, Ismaili N, Bath KG, Lee FS, Garabedian MJ, Chao MV.

Proc Natl Acad Sci U S A. 2012 Jan 24;109(4):1305-10. doi: 10.1073/pnas.1114122109. Epub 2012 Jan 9.

2.

Glucocorticoid-dependent phosphorylation of the transcriptional coregulator GRIP1.

Dobrovolna J, Chinenov Y, Kennedy MA, Liu B, Rogatsky I.

Mol Cell Biol. 2012 Feb;32(4):730-9. doi: 10.1128/MCB.06473-11. Epub 2011 Dec 12.

3.

Cellular uptake and intracellular trafficking of antisense and siRNA oligonucleotides.

Juliano RL, Ming X, Nakagawa O.

Bioconjug Chem. 2012 Feb 15;23(2):147-57. doi: 10.1021/bc200377d. Epub 2011 Oct 27. Review.

4.

Targeting several CAG expansion diseases by a single antisense oligonucleotide.

Evers MM, Pepers BA, van Deutekom JC, Mulders SA, den Dunnen JT, Aartsma-Rus A, van Ommen GJ, van Roon-Mom WM.

PLoS One. 2011;6(9):e24308. doi: 10.1371/journal.pone.0024308. Epub 2011 Sep 1.

5.

Antisense-mediated RNA targeting: versatile and expedient genetic manipulation in the brain.

Zalachoras I, Evers MM, van Roon-Mom WM, Aartsma-Rus AM, Meijer OC.

Front Mol Neurosci. 2011 Jul 19;4:10. doi: 10.3389/fnmol.2011.00010. eCollection 2011.

6.

Interactions of the mineralocorticoid receptor--within and without.

Yang J, Fuller PJ.

Mol Cell Endocrinol. 2012 Mar 24;350(2):196-205. doi: 10.1016/j.mce.2011.07.001. Epub 2011 Jul 18. Review.

PMID:
21784126
7.

Transcription factor AP1 potentiates chromatin accessibility and glucocorticoid receptor binding.

Biddie SC, John S, Sabo PJ, Thurman RE, Johnson TA, Schiltz RL, Miranda TB, Sung MH, Trump S, Lightman SL, Vinson C, Stamatoyannopoulos JA, Hager GL.

Mol Cell. 2011 Jul 8;43(1):145-55. doi: 10.1016/j.molcel.2011.06.016.

8.

The effect of Ndrg2 expression on astroglial activation.

Takeichi T, Takarada-Iemata M, Hashida K, Sudo H, Okuda T, Kokame K, Hatano T, Takanashi M, Funabe S, Hattori N, Kitamura O, Kitao Y, Hori O.

Neurochem Int. 2011 Aug;59(1):21-7. doi: 10.1016/j.neuint.2011.03.019. Epub 2011 Jun 13.

PMID:
21672576
9.

Dynamics of coregulator-induced conformational perturbations in androgen receptor ligand binding domain.

Zakharov MN, Pillai BK, Bhasin S, Ulloor J, Istomin AY, Guo C, Godzik A, Kumar R, Jasuja R.

Mol Cell Endocrinol. 2011 Jul 20;341(1-2):1-8. doi: 10.1016/j.mce.2011.03.003. Epub 2011 May 14.

PMID:
21605623
10.

Systemic administration of PRO051 in Duchenne's muscular dystrophy.

Goemans NM, Tulinius M, van den Akker JT, Burm BE, Ekhart PF, Heuvelmans N, Holling T, Janson AA, Platenburg GJ, Sipkens JA, Sitsen JM, Aartsma-Rus A, van Ommen GJ, Buyse G, Darin N, Verschuuren JJ, Campion GV, de Kimpe SJ, van Deutekom JC.

N Engl J Med. 2011 Apr 21;364(16):1513-22. doi: 10.1056/NEJMoa1011367. Epub 2011 Mar 23. Erratum in: N Engl J Med. 2011 Oct 6;365(14):1361.

11.

Mechanisms of single-stranded phosphorothioate modified antisense oligonucleotide accumulation in hepatocytes.

Koller E, Vincent TM, Chappell A, De S, Manoharan M, Bennett CF.

Nucleic Acids Res. 2011 Jun;39(11):4795-807. doi: 10.1093/nar/gkr089. Epub 2011 Feb 23.

12.

Region-specific involvement of BDNF secretion and synthesis in conditioned taste aversion memory formation.

Ma L, Wang DD, Zhang TY, Yu H, Wang Y, Huang SH, Lee FS, Chen ZY.

J Neurosci. 2011 Feb 9;31(6):2079-90. doi: 10.1523/JNEUROSCI.5348-10.2011.

13.

The central amygdala nucleus via corticotropin-releasing factor is necessary for time-limited consolidation processing but not storage of contextual fear memory.

Pitts MW, Takahashi LK.

Neurobiol Learn Mem. 2011 Jan;95(1):86-91. doi: 10.1016/j.nlm.2010.11.006. Epub 2010 Nov 17.

14.

Antisense oligonucleotides and spinal muscular atrophy: skipping along.

Burghes AH, McGovern VL.

Genes Dev. 2010 Aug 1;24(15):1574-9. doi: 10.1101/gad.1961710.

15.

Antisense correction of SMN2 splicing in the CNS rescues necrosis in a type III SMA mouse model.

Hua Y, Sahashi K, Hung G, Rigo F, Passini MA, Bennett CF, Krainer AR.

Genes Dev. 2010 Aug 1;24(15):1634-44. doi: 10.1101/gad.1941310. Epub 2010 Jul 12.

16.

Off-target effects related to the phosphorothioate modification of nucleic acids.

Winkler J, Stessl M, Amartey J, Noe CR.

ChemMedChem. 2010 Aug 2;5(8):1344-52. doi: 10.1002/cmdc.201000156.

PMID:
20544786
17.

Repair of pre-mRNA splicing: prospects for a therapy for spinal muscular atrophy.

Nlend Nlend R, Meyer K, Schümperli D.

RNA Biol. 2010 Jul-Aug;7(4):430-40. Epub 2010 Jul 1. Review.

18.

Preclinical PK and PD studies on 2'-O-methyl-phosphorothioate RNA antisense oligonucleotides in the mdx mouse model.

Heemskerk H, de Winter C, van Kuik P, Heuvelmans N, Sabatelli P, Rimessi P, Braghetta P, van Ommen GJ, de Kimpe S, Ferlini A, Aartsma-Rus A, van Deutekom JC.

Mol Ther. 2010 Jun;18(6):1210-7. doi: 10.1038/mt.2010.72. Epub 2010 Apr 20.

19.

Secretory mechanisms and intercellular transfer of microRNAs in living cells.

Kosaka N, Iguchi H, Yoshioka Y, Takeshita F, Matsuki Y, Ochiya T.

J Biol Chem. 2010 Jun 4;285(23):17442-52. doi: 10.1074/jbc.M110.107821. Epub 2010 Mar 30.

20.

Chronic stress alters the density and morphology of microglia in a subset of stress-responsive brain regions.

Tynan RJ, Naicker S, Hinwood M, Nalivaiko E, Buller KM, Pow DV, Day TA, Walker FR.

Brain Behav Immun. 2010 Oct;24(7):1058-68. doi: 10.1016/j.bbi.2010.02.001. Epub 2010 Feb 11.

PMID:
20153418

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