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Items: 1 to 20 of 57

1.

Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice.

Luk KC, Kehm VM, Zhang B, O'Brien P, Trojanowski JQ, Lee VM.

J Exp Med. 2012 May 7;209(5):975-86. doi: 10.1084/jem.20112457. Epub 2012 Apr 16.

2.

Recent advances in the genetics of the ALS-FTLD complex.

Morris HR, Waite AJ, Williams NM, Neal JW, Blake DJ.

Curr Neurol Neurosci Rep. 2012 Jun;12(3):243-50. doi: 10.1007/s11910-012-0268-5. Review.

PMID:
22477152
3.

Trans-cellular propagation of Tau aggregation by fibrillar species.

Kfoury N, Holmes BB, Jiang H, Holtzman DM, Diamond MI.

J Biol Chem. 2012 Jun 1;287(23):19440-51. doi: 10.1074/jbc.M112.346072. Epub 2012 Mar 29.

4.

Predicting regional neurodegeneration from the healthy brain functional connectome.

Zhou J, Gennatas ED, Kramer JH, Miller BL, Seeley WW.

Neuron. 2012 Mar 22;73(6):1216-27. doi: 10.1016/j.neuron.2012.03.004. Epub 2012 Mar 21.

5.

A network diffusion model of disease progression in dementia.

Raj A, Kuceyeski A, Weiner M.

Neuron. 2012 Mar 22;73(6):1204-15. doi: 10.1016/j.neuron.2011.12.040. Epub 2012 Mar 21.

6.

An over-oxidized form of superoxide dismutase found in sporadic amyotrophic lateral sclerosis with bulbar onset shares a toxic mechanism with mutant SOD1.

Guareschi S, Cova E, Cereda C, Ceroni M, Donetti E, Bosco DA, Trotti D, Pasinelli P.

Proc Natl Acad Sci U S A. 2012 Mar 27;109(13):5074-9. doi: 10.1073/pnas.1115402109. Epub 2012 Mar 13.

7.

Donation after cardiac death in amyotrophic lateral sclerosis: stepping forward into uncertain waters.

Sulmasy DP.

Ann Neurol. 2012 Feb;71(2):151-3. doi: 10.1002/ana.22661. No abstract available.

PMID:
22367986
8.

Organ donation after cardiac death in amyotrophic lateral sclerosis.

Toossi S, Lomen-Hoerth C, Josephson SA, Gropper MA, Roberts J, Patton K, Smith WS.

Ann Neurol. 2012 Feb;71(2):154-6. doi: 10.1002/ana.22525. Epub 2012 Feb 14.

PMID:
22334377
9.

A yeast functional screen predicts new candidate ALS disease genes.

Couthouis J, Hart MP, Shorter J, DeJesus-Hernandez M, Erion R, Oristano R, Liu AX, Ramos D, Jethava N, Hosangadi D, Epstein J, Chiang A, Diaz Z, Nakaya T, Ibrahim F, Kim HJ, Solski JA, Williams KL, Mojsilovic-Petrovic J, Ingre C, Boylan K, Graff-Radford NR, Dickson DW, Clay-Falcone D, Elman L, McCluskey L, Greene R, Kalb RG, Lee VM, Trojanowski JQ, Ludolph A, Robberecht W, Andersen PM, Nicholson GA, Blair IP, King OD, Bonini NM, Van Deerlin V, Rademakers R, Mourelatos Z, Gitler AD.

Proc Natl Acad Sci U S A. 2011 Dec 27;108(52):20881-90. doi: 10.1073/pnas.1109434108. Epub 2011 Nov 7.

10.

The seeds of neurodegeneration: prion-like spreading in ALS.

Polymenidou M, Cleveland DW.

Cell. 2011 Oct 28;147(3):498-508. doi: 10.1016/j.cell.2011.10.011.

11.

Clinical genetics of amyotrophic lateral sclerosis: what do we really know?

Andersen PM, Al-Chalabi A.

Nat Rev Neurol. 2011 Oct 11;7(11):603-15. doi: 10.1038/nrneurol.2011.150. Review.

PMID:
21989245
12.

Astrocytes carrying the superoxide dismutase 1 (SOD1G93A) mutation induce wild-type motor neuron degeneration in vivo.

Papadeas ST, Kraig SE, O'Banion C, Lepore AC, Maragakis NJ.

Proc Natl Acad Sci U S A. 2011 Oct 25;108(43):17803-8. doi: 10.1073/pnas.1103141108. Epub 2011 Oct 3.

13.

Onset and spreading patterns of lower motor neuron involvements predict survival in sporadic amyotrophic lateral sclerosis.

Fujimura-Kiyono C, Kimura F, Ishida S, Nakajima H, Hosokawa T, Sugino M, Hanafusa T.

J Neurol Neurosurg Psychiatry. 2011 Nov;82(11):1244-9. doi: 10.1136/jnnp-2011-300141. Epub 2011 Sep 15.

PMID:
21921087
14.

Passive immunization with anti-Tau antibodies in two transgenic models: reduction of Tau pathology and delay of disease progression.

Chai X, Wu S, Murray TK, Kinley R, Cella CV, Sims H, Buckner N, Hanmer J, Davies P, O'Neill MJ, Hutton ML, Citron M.

J Biol Chem. 2011 Sep 30;286(39):34457-67. doi: 10.1074/jbc.M111.229633. Epub 2011 Aug 12.

15.

Symptomatic and proven de novo amyloid polyneuropathy in familial amyloid polyneuropathy domino liver recipients.

Adams D, Lacroix C, Antonini T, Lozeron P, Denier C, Kreib AM, Epelbaum S, Blandin F, Karam V, Azoulay D, Adam R, Castaing D, Samuel D.

Amyloid. 2011 Jun;18 Suppl 1:174-7. doi: 10.3109/13506129.2011.574354065. No abstract available. Erratum in: Amyloid. 2011 Jun;18 Suppl 1:177.

PMID:
21838477
16.

Astrocytes from familial and sporadic ALS patients are toxic to motor neurons.

Haidet-Phillips AM, Hester ME, Miranda CJ, Meyer K, Braun L, Frakes A, Song S, Likhite S, Murtha MJ, Foust KD, Rao M, Eagle A, Kammesheidt A, Christensen A, Mendell JR, Burghes AH, Kaspar BK.

Nat Biotechnol. 2011 Aug 10;29(9):824-8. doi: 10.1038/nbt.1957.

17.

Prion-like acceleration of a synucleinopathy in a transgenic mouse model.

Mougenot AL, Nicot S, Bencsik A, Morignat E, Verchère J, Lakhdar L, Legastelois S, Baron T.

Neurobiol Aging. 2012 Sep;33(9):2225-8. doi: 10.1016/j.neurobiolaging.2011.06.022. Epub 2011 Aug 3.

PMID:
21813214
18.

Onset and spreading patterns of upper and lower motor neuron symptoms in amyotrophic lateral sclerosis.

Körner S, Kollewe K, Fahlbusch M, Zapf A, Dengler R, Krampfl K, Petri S.

Muscle Nerve. 2011 May;43(5):636-42. doi: 10.1002/mus.21936.

PMID:
21484822
19.

A "two-hit" hypothesis for inclusion formation by carboxyl-terminal fragments of TDP-43 protein linked to RNA depletion and impaired microtubule-dependent transport.

Pesiridis GS, Tripathy K, Tanik S, Trojanowski JQ, Lee VM.

J Biol Chem. 2011 May 27;286(21):18845-55. doi: 10.1074/jbc.M111.231118. Epub 2011 Mar 24.

20.

A seeding reaction recapitulates intracellular formation of Sarkosyl-insoluble transactivation response element (TAR) DNA-binding protein-43 inclusions.

Furukawa Y, Kaneko K, Watanabe S, Yamanaka K, Nukina N.

J Biol Chem. 2011 May 27;286(21):18664-72. doi: 10.1074/jbc.M111.231209. Epub 2011 Mar 24.

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