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Items: 1 to 20 of 84

1.

The tryptophan hydroxylase inhibitor LX1031 shows clinical benefit in patients with nonconstipating irritable bowel syndrome.

Brown PM, Drossman DA, Wood AJ, Cline GA, Frazier KS, Jackson JI, Bronner J, Freiman J, Zambrowicz B, Sands A, Gershon MD.

Gastroenterology. 2011 Aug;141(2):507-16. doi: 10.1053/j.gastro.2011.05.005. Epub 2011 May 18.

2.

Intestinal serotonin release, sensory neuron activation, and abdominal pain in irritable bowel syndrome.

Cremon C, Carini G, Wang B, Vasina V, Cogliandro RF, De Giorgio R, Stanghellini V, Grundy D, Tonini M, De Ponti F, Corinaldesi R, Barbara G.

Am J Gastroenterol. 2011 Jul;106(7):1290-8. doi: 10.1038/ajg.2011.86. Epub 2011 Mar 22.

PMID:
21427712
3.

Impaired uptake of serotonin by platelets from patients with irritable bowel syndrome correlates with duodenal immune activation.

Foley S, Garsed K, Singh G, Duroudier NP, Swan C, Hall IP, Zaitoun A, Bennett A, Marsden C, Holmes G, Walls A, Spiller RC.

Gastroenterology. 2011 May;140(5):1434-43.e1. doi: 10.1053/j.gastro.2011.01.052. Epub 2011 Mar 23.

PMID:
21315720
4.

Serotonin activates dendritic cell function in the context of gut inflammation.

Li N, Ghia JE, Wang H, McClemens J, Cote F, Suehiro Y, Mallet J, Khan WI.

Am J Pathol. 2011 Feb;178(2):662-71. doi: 10.1016/j.ajpath.2010.10.028.

5.

Enteroendocrine cells: neglected players in gastrointestinal disorders?

Moran GW, Leslie FC, Levison SE, Worthington J, McLaughlin JT.

Therap Adv Gastroenterol. 2008 Jul;1(1):51-60. doi: 10.1177/1756283X08093943. Erratum in: Therap Adv Gastroenterol. 2008 Sep;1(2):144. Worthington, J [added].

6.

Association of symptoms with gastrointestinal microbiota in irritable bowel syndrome.

Malinen E, Krogius-Kurikka L, Lyra A, Nikkilä J, Jääskeläinen A, Rinttilä T, Vilpponen-Salmela T, von Wright AJ, Palva A.

World J Gastroenterol. 2010 Sep 28;16(36):4532-40.

7.

Anti-mitogenic and apoptotic effects of 5-HT1B receptor antagonist on HT29 colorectal cancer cell line.

Ataee R, Ajdary S, Zarrindast M, Rezayat M, Hayatbakhsh MR.

J Cancer Res Clin Oncol. 2010 Oct;136(10):1461-9. doi: 10.1007/s00432-010-0801-3. Epub 2010 Mar 21.

PMID:
20306273
8.

Serotonin signaling is altered in irritable bowel syndrome with diarrhea but not in functional dyspepsia in pediatric age patients.

Faure C, Patey N, Gauthier C, Brooks EM, Mawe GM.

Gastroenterology. 2010 Jul;139(1):249-58. doi: 10.1053/j.gastro.2010.03.032. Epub 2010 Mar 17.

9.

Enhancement of intestinal inflammation in mice lacking interleukin 10 by deletion of the serotonin reuptake transporter.

Haub S, Ritze Y, Bergheim I, Pabst O, Gershon MD, Bischoff SC.

Neurogastroenterol Motil. 2010 Jul;22(7):826-34, e229. doi: 10.1111/j.1365-2982.2010.01479.x. Epub 2010 Mar 8.

10.

Serotonin has a key role in pathogenesis of experimental colitis.

Ghia JE, Li N, Wang H, Collins M, Deng Y, El-Sharkawy RT, Côté F, Mallet J, Khan WI.

Gastroenterology. 2009 Nov;137(5):1649-60. doi: 10.1053/j.gastro.2009.08.041. Epub 2009 Aug 23.

PMID:
19706294
11.

Doublecortin and CaM kinase-like-1 and leucine-rich-repeat-containing G-protein-coupled receptor mark quiescent and cycling intestinal stem cells, respectively.

May R, Sureban SM, Hoang N, Riehl TE, Lightfoot SA, Ramanujam R, Wyche JH, Anant S, Houchen CW.

Stem Cells. 2009 Oct;27(10):2571-9. doi: 10.1002/stem.193.

12.

5-hydroxytryptamine modulates migration, cytokine and chemokine release and T-cell priming capacity of dendritic cells in vitro and in vivo.

Müller T, Dürk T, Blumenthal B, Grimm M, Cicko S, Panther E, Sorichter S, Herouy Y, Di Virgilio F, Ferrari D, Norgauer J, Idzko M.

PLoS One. 2009 Jul 31;4(7):e6453. doi: 10.1371/journal.pone.0006453.

13.

Antidepressant use and colorectal cancer risk.

Coogan PF, Strom BL, Rosenberg L.

Pharmacoepidemiol Drug Saf. 2009 Nov;18(11):1111-4. doi: 10.1002/pds.1808.

14.

Efficacy of 5-HT3 antagonists and 5-HT4 agonists in irritable bowel syndrome: systematic review and meta-analysis.

Ford AC, Brandt LJ, Young C, Chey WD, Foxx-Orenstein AE, Moayyedi P.

Am J Gastroenterol. 2009 Jul;104(7):1831-43; quiz 1844. doi: 10.1038/ajg.2009.223. Epub 2009 May 26. Review.

PMID:
19471254
15.

Role of serotonin in gastrointestinal motility and irritable bowel syndrome.

Sikander A, Rana SV, Prasad KK.

Clin Chim Acta. 2009 May;403(1-2):47-55. doi: 10.1016/j.cca.2009.01.028. Epub 2009 Feb 4. Review.

PMID:
19361459
16.

Serotonin in the gastrointestinal tract.

Camilleri M.

Curr Opin Endocrinol Diabetes Obes. 2009 Feb;16(1):53-9. Review.

17.

Role of serotonin in intestinal inflammation: knockout of serotonin reuptake transporter exacerbates 2,4,6-trinitrobenzene sulfonic acid colitis in mice.

Bischoff SC, Mailer R, Pabst O, Weier G, Sedlik W, Li Z, Chen JJ, Murphy DL, Gershon MD.

Am J Physiol Gastrointest Liver Physiol. 2009 Mar;296(3):G685-95. doi: 10.1152/ajpgi.90685.2008. Epub 2008 Dec 18.

18.

5-hydroxytryptamine and the gastrointestinal tract: where next?

Sanger GJ.

Trends Pharmacol Sci. 2008 Sep;29(9):465-71. doi: 10.1016/j.tips.2008.06.008. Review.

PMID:
19086255
19.

IL1beta- and LPS-induced serotonin secretion is increased in EC cells derived from Crohn's disease.

Kidd M, Gustafsson BI, Drozdov I, Modlin IM.

Neurogastroenterol Motil. 2009 Apr;21(4):439-50. doi: 10.1111/j.1365-2982.2008.01210.x. Epub 2008 Oct 25.

20.

Serotonin and GI clinical disorders.

Spiller R.

Neuropharmacology. 2008 Nov;55(6):1072-80. doi: 10.1016/j.neuropharm.2008.07.016. Epub 2008 Jul 19. Review.

PMID:
18687345

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