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β1 integrin gene excision in the adult murine cardiac myocyte causes defective mechanical and signaling responses.

Li R, Wu Y, Manso AM, Gu Y, Liao P, Israeli S, Yajima T, Nguyen U, Huang MS, Dalton ND, Peterson KL, Ross RS.

Am J Pathol. 2012 Mar;180(3):952-62. doi: 10.1016/j.ajpath.2011.12.007.


Jarid2 (Jumonji, AT rich interactive domain 2) regulates NOTCH1 expression via histone modification in the developing heart.

Mysliwiec MR, Carlson CD, Tietjen J, Hung H, Ansari AZ, Lee Y.

J Biol Chem. 2012 Jan 6;287(2):1235-41. doi: 10.1074/jbc.M111.315945.


Filamin C plays an essential role in the maintenance of the structural integrity of cardiac and skeletal muscles, revealed by the medaka mutant zacro.

Fujita M, Mitsuhashi H, Isogai S, Nakata T, Kawakami A, Nonaka I, Noguchi S, Hayashi YK, Nishino I, Kudo A.

Dev Biol. 2012 Jan 1;361(1):79-89. doi: 10.1016/j.ydbio.2011.10.008.


Muscle actin is polyubiquitinylated in vitro and in vivo and targeted for breakdown by the E3 ligase MuRF1.

Polge C, Heng AE, Jarzaguet M, Ventadour S, Claustre A, Combaret L, Béchet D, Matondo M, Uttenweiler-Joseph S, Monsarrat B, Attaix D, Taillandier D.

FASEB J. 2011 Nov;25(11):3790-802. doi: 10.1096/fj.11-180968.


Significance of thymosin β4 and implication of PINCH-1-ILK-α-parvin (PIP) complex in human dilated cardiomyopathy.

Sopko N, Qin Y, Finan A, Dadabayev A, Chigurupati S, Qin J, Penn MS, Gupta S.

PLoS One. 2011;6(5):e20184. doi: 10.1371/journal.pone.0020184.


Endothelial Jarid2/Jumonji is required for normal cardiac development and proper Notch1 expression.

Mysliwiec MR, Bresnick EH, Lee Y.

J Biol Chem. 2011 May 13;286(19):17193-204. doi: 10.1074/jbc.M110.205146.


Cardiac Z-disc signaling network.

Frank D, Frey N.

J Biol Chem. 2011 Mar 25;286(12):9897-904. doi: 10.1074/jbc.R110.174268. Review.


Molecular pathways underlying cardiac remodeling during pathophysiological stimulation.

Kehat I, Molkentin JD.

Circulation. 2010 Dec 21;122(25):2727-35. doi: 10.1161/CIRCULATIONAHA.110.942268. No abstract available.


Extracellular signal-regulated kinases 1 and 2 regulate the balance between eccentric and concentric cardiac growth.

Kehat I, Davis J, Tiburcy M, Accornero F, Saba-El-Leil MK, Maillet M, York AJ, Lorenz JN, Zimmermann WH, Meloche S, Molkentin JD.

Circ Res. 2011 Jan 21;108(2):176-83. doi: 10.1161/CIRCRESAHA.110.231514.


Identification of residues within tropomodulin-1 responsible for its localization at the pointed ends of the actin filaments in cardiac myocytes.

Tsukada T, Kotlyanskaya L, Huynh R, Desai B, Novak SM, Kajava AV, Gregorio CC, Kostyukova AS.

J Biol Chem. 2011 Jan 21;286(3):2194-204. doi: 10.1074/jbc.M110.186924.


Myomasp/LRRC39, a heart- and muscle-specific protein, is a novel component of the sarcomeric M-band and is involved in stretch sensing.

Will RD, Eden M, Just S, Hansen A, Eder A, Frank D, Kuhn C, Seeger TS, Oehl U, Wiemann S, Korn B, Koegl M, Rottbauer W, Eschenhagen T, Katus HA, Frey N.

Circ Res. 2010 Nov 12;107(10):1253-64. doi: 10.1161/CIRCRESAHA.110.222372.


Ca2+/calmodulin-dependent kinase IIdelta causes heart failure by accumulation of p53 in dilated cardiomyopathy.

Toko H, Takahashi H, Kayama Y, Oka T, Minamino T, Okada S, Morimoto S, Zhan DY, Terasaki F, Anderson ME, Inoue M, Yao A, Nagai R, Kitaura Y, Sasaguri T, Komuro I.

Circulation. 2010 Aug 31;122(9):891-9. doi: 10.1161/CIRCULATIONAHA.109.935296.


LRRC26 auxiliary protein allows BK channel activation at resting voltage without calcium.

Yan J, Aldrich RW.

Nature. 2010 Jul 22;466(7305):513-6. doi: 10.1038/nature09162.


Loss of enigma homolog protein results in dilated cardiomyopathy.

Cheng H, Kimura K, Peter AK, Cui L, Ouyang K, Shen T, Liu Y, Gu Y, Dalton ND, Evans SM, Knowlton KU, Peterson KL, Chen J.

Circ Res. 2010 Aug 6;107(3):348-56. doi: 10.1161/CIRCRESAHA.110.218735.


Up-regulation of type 2 iodothyronine deiodinase in dilated cardiomyopathy.

Wang YY, Morimoto S, Du CK, Lu QW, Zhan DY, Tsutsumi T, Ide T, Miwa Y, Takahashi-Yanaga F, Sasaguri T.

Cardiovasc Res. 2010 Sep 1;87(4):636-46. doi: 10.1093/cvr/cvq133.


Intramyocardial VEGF-B167 gene delivery delays the progression towards congestive failure in dogs with pacing-induced dilated cardiomyopathy.

Pepe M, Mamdani M, Zentilin L, Csiszar A, Qanud K, Zacchigna S, Ungvari Z, Puligadda U, Moimas S, Xu X, Edwards JG, Hintze TH, Giacca M, Recchia FA.

Circ Res. 2010 Jun 25;106(12):1893-903. doi: 10.1161/CIRCRESAHA.110.220855.


Mechanical stress-induced sarcomere assembly for cardiac muscle growth in length and width.

Russell B, Curtis MW, Koshman YE, Samarel AM.

J Mol Cell Cardiol. 2010 May;48(5):817-23. doi: 10.1016/j.yjmcc.2010.02.016. Review.


TLRR (lrrc67) interacts with PP1 and is associated with a cytoskeletal complex in the testis.

Wang R, Kaul A, Sperry AO.

Biol Cell. 2010 Jan 13;102(3):173-89. doi: 10.1042/BC20090091.


Nexilin mutations destabilize cardiac Z-disks and lead to dilated cardiomyopathy.

Hassel D, Dahme T, Erdmann J, Meder B, Huge A, Stoll M, Just S, Hess A, Ehlermann P, Weichenhan D, Grimmler M, Liptau H, Hetzer R, Regitz-Zagrosek V, Fischer C, Nürnberg P, Schunkert H, Katus HA, Rottbauer W.

Nat Med. 2009 Nov;15(11):1281-8. doi: 10.1038/nm.2037.

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