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Items: 1 to 20 of 44

1.

Rare missense variants in CHRNB4 are associated with reduced risk of nicotine dependence.

Haller G, Druley T, Vallania FL, Mitra RD, Li P, Akk G, Steinbach JH, Breslau N, Johnson E, Hatsukami D, Stitzel J, Bierut LJ, Goate AM.

Hum Mol Genet. 2012 Feb 1;21(3):647-55. doi: 10.1093/hmg/ddr498. Epub 2011 Oct 31.

2.

Comparisons of seven algorithms for pathway analysis using the WTCCC Crohn's Disease dataset.

Gui H, Li M, Sham PC, Cherny SS.

BMC Res Notes. 2011 Oct 7;4:386. doi: 10.1186/1756-0500-4-386.

3.

The contribution of common CYP2A6 alleles to variation in nicotine metabolism among European-Americans.

Bloom J, Hinrichs AL, Wang JC, von Weymarn LB, Kharasch ED, Bierut LJ, Goate A, Murphy SE.

Pharmacogenet Genomics. 2011 Jul;21(7):403-16. doi: 10.1097/FPC.0b013e328346e8c0.

4.

A 3p26-3p25 genetic linkage finding for DSM-IV major depression in heavy smoking families.

Pergadia ML, Glowinski AL, Wray NR, Agrawal A, Saccone SF, Loukola A, Broms U, Korhonen T, Penninx BW, Grant JD, Nelson EC, Henders AK, Schrage AJ, Chou YL, Keskitalo-Vuokko K, Zhu Q, Gordon SD, Vink JM, de Geus EJ, Macgregor S, Liu JZ, Willemsen G, Medland SE, Boomsma DI, Montgomery GW, Rice JP, Goate AM, Heath AC, Kaprio J, Martin NG, Madden PA.

Am J Psychiatry. 2011 Aug;168(8):848-52. doi: 10.1176/appi.ajp.2011.10091319. Epub 2011 May 15.

5.

Common polymorphisms in FMO1 are associated with nicotine dependence.

Hinrichs AL, Murphy SE, Wang JC, Saccone S, Saccone N, Steinbach JH, Goate A, Stevens VL, Bierut LJ.

Pharmacogenet Genomics. 2011 Jul;21(7):397-402. doi: 10.1097/FPC.0b013e328346886f.

6.

A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications.

Heath AC, Whitfield JB, Martin NG, Pergadia ML, Goate AM, Lind PA, McEvoy BP, Schrage AJ, Grant JD, Chou YL, Zhu R, Henders AK, Medland SE, Gordon SD, Nelson EC, Agrawal A, Nyholt DR, Bucholz KK, Madden PA, Montgomery GW.

Biol Psychiatry. 2011 Sep 15;70(6):513-8. doi: 10.1016/j.biopsych.2011.02.028. Epub 2011 May 6.

7.

Estimating missing heritability for disease from genome-wide association studies.

Lee SH, Wray NR, Goddard ME, Visscher PM.

Am J Hum Genet. 2011 Mar 11;88(3):294-305. doi: 10.1016/j.ajhg.2011.02.002. Epub 2011 Mar 3.

8.

Nicotine-mediated suppression of the retinoic acid metabolizing enzyme CYP26A1 limits the oncogenic potential of breast cancer.

Osanai M, Lee GH.

Cancer Sci. 2011 Jun;102(6):1158-63. doi: 10.1111/j.1349-7006.2011.01920.x. Epub 2011 Mar 28.

9.

Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease.

Jones L, Holmans PA, Hamshere ML, Harold D, Moskvina V, Ivanov D, Pocklington A, Abraham R, Hollingworth P, Sims R, Gerrish A, Pahwa JS, Jones N, Stretton A, Morgan AR, Lovestone S, Powell J, Proitsi P, Lupton MK, Brayne C, Rubinsztein DC, Gill M, Lawlor B, Lynch A, Morgan K, Brown KS, Passmore PA, Craig D, McGuinness B, Todd S, Holmes C, Mann D, Smith AD, Love S, Kehoe PG, Mead S, Fox N, Rossor M, Collinge J, Maier W, Jessen F, Schürmann B, Heun R, Kölsch H, van den Bussche H, Heuser I, Peters O, Kornhuber J, Wiltfang J, Dichgans M, Frölich L, Hampel H, Hüll M, Rujescu D, Goate AM, Kauwe JS, Cruchaga C, Nowotny P, Morris JC, Mayo K, Livingston G, Bass NJ, Gurling H, McQuillin A, Gwilliam R, Deloukas P, Al-Chalabi A, Shaw CE, Singleton AB, Guerreiro R, Mühleisen TW, Nöthen MM, Moebus S, Jöckel KH, Klopp N, Wichmann HE, Rüther E, Carrasquillo MM, Pankratz VS, Younkin SG, Hardy J, O'Donovan MC, Owen MJ, Williams J.

PLoS One. 2010 Nov 15;5(11):e13950. doi: 10.1371/journal.pone.0013950. Erratum in: PLoS One. 2011;6(2). doi:10.1371/annotation/a0bb886d-d345-4a20-a82e-adce9b047798. Heun, Reinhard [added]; Kölsch, Heike [added].

10.

Analysing biological pathways in genome-wide association studies.

Wang K, Li M, Hakonarson H.

Nat Rev Genet. 2010 Dec;11(12):843-54. doi: 10.1038/nrg2884. Review.

PMID:
21085203
11.

Impact of repeated measures and sample selection on genome-wide association studies of fasting glucose.

Rasmussen-Torvik LJ, Alonso A, Li M, Kao W, Köttgen A, Yan Y, Couper D, Boerwinkle E, Bielinski SJ, Pankow JS.

Genet Epidemiol. 2010 Nov;34(7):665-73. doi: 10.1002/gepi.20525.

12.

Common inherited variation in mitochondrial genes is not enriched for associations with type 2 diabetes or related glycemic traits.

Segrè AV; DIAGRAM Consortium; MAGIC investigators, Groop L, Mootha VK, Daly MJ, Altshuler D.

PLoS Genet. 2010 Aug 12;6(8). pii: e1001058. doi: 10.1371/journal.pgen.1001058.

13.

The perception of quinine taste intensity is associated with common genetic variants in a bitter receptor cluster on chromosome 12.

Reed DR, Zhu G, Breslin PA, Duke FF, Henders AK, Campbell MJ, Montgomery GW, Medland SE, Martin NG, Wright MJ.

Hum Mol Genet. 2010 Nov 1;19(21):4278-85. doi: 10.1093/hmg/ddq324. Epub 2010 Jul 30.

14.

Multiple cholinergic nicotinic receptor genes affect nicotine dependence risk in African and European Americans.

Saccone NL, Schwantes-An TH, Wang JC, Grucza RA, Breslau N, Hatsukami D, Johnson EO, Rice JP, Goate AM, Bierut LJ.

Genes Brain Behav. 2010 Oct;9(7):741-50. doi: 10.1111/j.1601-183X.2010.00608.x. Epub 2010 Jul 22.

15.

Common SNPs explain a large proportion of the heritability for human height.

Yang J, Benyamin B, McEvoy BP, Gordon S, Henders AK, Nyholt DR, Madden PA, Heath AC, Martin NG, Montgomery GW, Goddard ME, Visscher PM.

Nat Genet. 2010 Jul;42(7):565-9. doi: 10.1038/ng.608. Epub 2010 Jun 20.

16.

Genome-wide meta-analyses identify multiple loci associated with smoking behavior.

Tobacco and Genetics Consortium.

Nat Genet. 2010 May;42(5):441-7. doi: 10.1038/ng.571. Epub 2010 Apr 25.

17.

Meta-analysis and imputation refines the association of 15q25 with smoking quantity.

Liu JZ, Tozzi F, Waterworth DM, Pillai SG, Muglia P, Middleton L, Berrettini W, Knouff CW, Yuan X, Waeber G, Vollenweider P, Preisig M, Wareham NJ, Zhao JH, Loos RJ, Barroso I, Khaw KT, Grundy S, Barter P, Mahley R, Kesaniemi A, McPherson R, Vincent JB, Strauss J, Kennedy JL, Farmer A, McGuffin P, Day R, Matthews K, Bakke P, Gulsvik A, Lucae S, Ising M, Brueckl T, Horstmann S, Wichmann HE, Rawal R, Dahmen N, Lamina C, Polasek O, Zgaga L, Huffman J, Campbell S, Kooner J, Chambers JC, Burnett MS, Devaney JM, Pichard AD, Kent KM, Satler L, Lindsay JM, Waksman R, Epstein S, Wilson JF, Wild SH, Campbell H, Vitart V, Reilly MP, Li M, Qu L, Wilensky R, Matthai W, Hakonarson HH, Rader DJ, Franke A, Wittig M, Schäfer A, Uda M, Terracciano A, Xiao X, Busonero F, Scheet P, Schlessinger D, St Clair D, Rujescu D, Abecasis GR, Grabe HJ, Teumer A, Völzke H, Petersmann A, John U, Rudan I, Hayward C, Wright AF, Kolcic I, Wright BJ, Thompson JR, Balmforth AJ, Hall AS, Samani NJ, Anderson CA, Ahmad T, Mathew CG, Parkes M, Satsangi J, Caulfield M, Munroe PB, Farrall M, Dominiczak A, Worthington J, Thomson W, Eyre S, Barton A; Wellcome Trust Case Control Consortium, Mooser V, Francks C, Marchini J.

Nat Genet. 2010 May;42(5):436-40. doi: 10.1038/ng.572. Epub 2010 Apr 25.

18.

Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior.

Thorgeirsson TE, Gudbjartsson DF, Surakka I, Vink JM, Amin N, Geller F, Sulem P, Rafnar T, Esko T, Walter S, Gieger C, Rawal R, Mangino M, Prokopenko I, Mägi R, Keskitalo K, Gudjonsdottir IH, Gretarsdottir S, Stefansson H, Thompson JR, Aulchenko YS, Nelis M, Aben KK, den Heijer M, Dirksen A, Ashraf H, Soranzo N, Valdes AM, Steves C, Uitterlinden AG, Hofman A, Tönjes A, Kovacs P, Hottenga JJ, Willemsen G, Vogelzangs N, Döring A, Dahmen N, Nitz B, Pergadia ML, Saez B, De Diego V, Lezcano V, Garcia-Prats MD, Ripatti S, Perola M, Kettunen J, Hartikainen AL, Pouta A, Laitinen J, Isohanni M, Huei-Yi S, Allen M, Krestyaninova M, Hall AS, Jones GT, van Rij AM, Mueller T, Dieplinger B, Haltmayer M, Jonsson S, Matthiasson SE, Oskarsson H, Tyrfingsson T, Kiemeney LA, Mayordomo JI, Lindholt JS, Pedersen JH, Franklin WA, Wolf H, Montgomery GW, Heath AC, Martin NG, Madden PA, Giegling I, Rujescu D, Järvelin MR, Salomaa V, Stumvoll M, Spector TD, Wichmann HE, Metspalu A, Samani NJ, Penninx BW, Oostra BA, Boomsma DI, Tiemeier H, van Duijn CM, Kaprio J, Gulcher JR; ENGAGE Consortium, McCarthy MI, Peltonen L, Thorsteinsdottir U, Stefansson K.

Nat Genet. 2010 May;42(5):448-53. doi: 10.1038/ng.573. Epub 2010 Apr 25.

19.

A genome-wide association study of alcohol dependence.

Bierut LJ, Agrawal A, Bucholz KK, Doheny KF, Laurie C, Pugh E, Fisher S, Fox L, Howells W, Bertelsen S, Hinrichs AL, Almasy L, Breslau N, Culverhouse RC, Dick DM, Edenberg HJ, Foroud T, Grucza RA, Hatsukami D, Hesselbrock V, Johnson EO, Kramer J, Krueger RF, Kuperman S, Lynskey M, Mann K, Neuman RJ, Nöthen MM, Nurnberger JI Jr, Porjesz B, Ridinger M, Saccone NL, Saccone SF, Schuckit MA, Tischfield JA, Wang JC, Rietschel M, Goate AM, Rice JP; Gene, Environment Association Studies Consortium.

Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):5082-7. doi: 10.1073/pnas.0911109107. Epub 2010 Mar 2.

20.

Molecular pathways involved in neuronal cell adhesion and membrane scaffolding contribute to schizophrenia and bipolar disorder susceptibility.

O'Dushlaine C, Kenny E, Heron E, Donohoe G, Gill M, Morris D; International Schizophrenia Consortium, Corvin A.

Mol Psychiatry. 2011 Mar;16(3):286-92. doi: 10.1038/mp.2010.7. Epub 2010 Feb 16.

PMID:
20157312

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