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Items: 1 to 20 of 114


New roles of carboxypeptidase E in endocrine and neural function and cancer.

Cawley NX, Wetsel WC, Murthy SR, Park JJ, Pacak K, Loh YP.

Endocr Rev. 2012 Apr;33(2):216-53. doi: 10.1210/er.2011-1039. Epub 2012 Mar 7. Review.


The "go or grow" potential of gliomas is linked to the neuropeptide processing enzyme carboxypeptidase E and mediated by metabolic stress.

Höring E, Harter PN, Seznec J, Schittenhelm J, Bühring HJ, Bhattacharyya S, von Hattingen E, Zachskorn C, Mittelbronn M, Naumann U.

Acta Neuropathol. 2012 Jul;124(1):83-97. doi: 10.1007/s00401-011-0940-x. Epub 2012 Jan 15.


Betacellulin promotes cell proliferation in the neural stem cell niche and stimulates neurogenesis.

Gómez-Gaviro MV, Scott CE, Sesay AK, Matheu A, Booth S, Galichet C, Lovell-Badge R.

Proc Natl Acad Sci U S A. 2012 Jan 24;109(4):1317-22. doi: 10.1073/pnas.1016199109. Epub 2012 Jan 9.


Autotaxin and LPA receptor signaling in cancer.

Houben AJ, Moolenaar WH.

Cancer Metastasis Rev. 2011 Dec;30(3-4):557-65. doi: 10.1007/s10555-011-9319-7. Review.


Lake-front property: a unique germinal niche by the lateral ventricles of the adult brain.

Ihrie RA, Alvarez-Buylla A.

Neuron. 2011 May 26;70(4):674-86. doi: 10.1016/j.neuron.2011.05.004. Review.


An N-terminal truncated carboxypeptidase E splice isoform induces tumor growth and is a biomarker for predicting future metastasis in human cancers.

Lee TK, Murthy SR, Cawley NX, Dhanvantari S, Hewitt SM, Lou H, Lau T, Ma S, Huynh T, Wesley RA, Ng IO, Pacak K, Poon RT, Loh YP.

J Clin Invest. 2011 Mar;121(3):880-92. doi: 10.1172/JCI40433.


CSPG is a secreted factor that stimulates neural stem cell survival possibly by enhanced EGFR signaling.

Tham M, Ramasamy S, Gan HT, Ramachandran A, Poonepalli A, Yu YH, Ahmed S.

PLoS One. 2010 Dec 14;5(12):e15341. doi: 10.1371/journal.pone.0015341.


In vivo fate mapping and expression analysis reveals molecular hallmarks of prospectively isolated adult neural stem cells.

Beckervordersandforth R, Tripathi P, Ninkovic J, Bayam E, Lepier A, Stempfhuber B, Kirchhoff F, Hirrlinger J, Haslinger A, Lie DC, Beckers J, Yoder B, Irmler M, Götz M.

Cell Stem Cell. 2010 Dec 3;7(6):744-58. doi: 10.1016/j.stem.2010.11.017. Erratum in: Cell Stem Cell. 2011 Jan 7;8(1):119.


Notch and EGFR pathway interaction regulates neural stem cell number and self-renewal.

Aguirre A, Rubio ME, Gallo V.

Nature. 2010 Sep 16;467(7313):323-7. doi: 10.1038/nature09347.


Signaling in adult neurogenesis.

Mu Y, Lee SW, Gage FH.

Curr Opin Neurobiol. 2010 Aug;20(4):416-23. doi: 10.1016/j.conb.2010.04.010. Epub 2010 May 12.


Bone morphogenetic protein signaling in the developing telencephalon controls formation of the hippocampal dentate gyrus and modifies fear-related behavior.

Caronia G, Wilcoxon J, Feldman P, Grove EA.

J Neurosci. 2010 May 5;30(18):6291-301. doi: 10.1523/JNEUROSCI.0550-10.2010.


Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

Guo G, Huss M, Tong GQ, Wang C, Li Sun L, Clarke ND, Robson P.

Dev Cell. 2010 Apr 20;18(4):675-85. doi: 10.1016/j.devcel.2010.02.012.


PARM-1 is an endoplasmic reticulum molecule involved in endoplasmic reticulum stress-induced apoptosis in rat cardiac myocytes.

Isodono K, Takahashi T, Imoto H, Nakanishi N, Ogata T, Asada S, Adachi A, Ueyama T, Oh H, Matsubara H.

PLoS One. 2010 Mar 18;5(3):e9746. doi: 10.1371/journal.pone.0009746.


LPA receptors: subtypes and biological actions.

Choi JW, Herr DR, Noguchi K, Yung YC, Lee CW, Mutoh T, Lin ME, Teo ST, Park KE, Mosley AN, Chun J.

Annu Rev Pharmacol Toxicol. 2010;50:157-86. doi: 10.1146/annurev.pharmtox.010909.105753. Review.


A robust and high-throughput Cre reporting and characterization system for the whole mouse brain.

Madisen L, Zwingman TA, Sunkin SM, Oh SW, Zariwala HA, Gu H, Ng LL, Palmiter RD, Hawrylycz MJ, Jones AR, Lein ES, Zeng H.

Nat Neurosci. 2010 Jan;13(1):133-40. doi: 10.1038/nn.2467. Epub 2009 Dec 20.


Emerging roles of Wnts in the adult nervous system.

Inestrosa NC, Arenas E.

Nat Rev Neurosci. 2010 Feb;11(2):77-86. doi: 10.1038/nrn2755. Epub 2009 Dec 16. Review.


Orphan nuclear receptor TLX activates Wnt/beta-catenin signalling to stimulate neural stem cell proliferation and self-renewal.

Qu Q, Sun G, Li W, Yang S, Ye P, Zhao C, Yu RT, Gage FH, Evans RM, Shi Y.

Nat Cell Biol. 2010 Jan;12(1):31-40; sup pp 1-9. doi: 10.1038/ncb2001. Epub 2009 Dec 13.


FoxJ1-dependent gene expression is required for differentiation of radial glia into ependymal cells and a subset of astrocytes in the postnatal brain.

Jacquet BV, Salinas-Mondragon R, Liang H, Therit B, Buie JD, Dykstra M, Campbell K, Ostrowski LE, Brody SL, Ghashghaei HT.

Development. 2009 Dec;136(23):4021-31. doi: 10.1242/dev.041129.


Identification of secreted proteins associated with obesity and type 2 diabetes in Psammomys obesus.

Bolton K, Segal D, McMillan J, Sanigorski A, Collier G, Walder K.

Int J Obes (Lond). 2009 Oct;33(10):1153-65. doi: 10.1038/ijo.2009.148. Epub 2009 Jul 28.


Carboxypeptidase E knockout mice exhibit abnormal dendritic arborization and spine morphology in central nervous system neurons.

Woronowicz A, Cawley NX, Chang SY, Koshimizu H, Phillips AW, Xiong ZG, Loh YP.

J Neurosci Res. 2010 Jan;88(1):64-72. doi: 10.1002/jnr.22174.

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