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Items: 1 to 20 of 42

1.

Pregnane X receptor activation induces FGF19-dependent tumor aggressiveness in humans and mice.

Wang H, Venkatesh M, Li H, Goetz R, Mukherjee S, Biswas A, Zhu L, Kaubisch A, Wang L, Pullman J, Whitney K, Kuro-o M, Roig AI, Shay JW, Mohammadi M, Mani S.

J Clin Invest. 2011 Aug;121(8):3220-32. doi: 10.1172/JCI41514. Epub 2011 Jul 11.

2.

Deficiency of PXR decreases atherosclerosis in apoE-deficient mice.

Sui Y, Xu J, Rios-Pilier J, Zhou C.

J Lipid Res. 2011 Sep;52(9):1652-9. doi: 10.1194/jlr.M017376. Epub 2011 Jun 18.

3.

Post-translational modification of pregnane x receptor.

Staudinger JL, Xu C, Biswas A, Mani S.

Pharmacol Res. 2011 Jul;64(1):4-10. doi: 10.1016/j.phrs.2011.02.011. Epub 2011 Mar 21. Review.

4.

Regulation of drug-metabolizing enzymes by xenobiotic receptors: PXR and CAR.

Tolson AH, Wang H.

Adv Drug Deliv Rev. 2010 Oct 30;62(13):1238-49. doi: 10.1016/j.addr.2010.08.006. Epub 2010 Aug 17. Review.

5.

Hepatocyte nuclear factor 4{alpha} regulates rifampicin-mediated induction of CYP2C genes in primary cultures of human hepatocytes.

Rana R, Chen Y, Ferguson SS, Kissling GE, Surapureddi S, Goldstein JA.

Drug Metab Dispos. 2010 Apr;38(4):591-9. doi: 10.1124/dmd.109.030387. Epub 2010 Jan 19.

6.

Activation of pregnane X receptor (PXR) and constitutive androstane receptor (CAR) by herbal medicines.

Chang TK.

AAPS J. 2009 Sep;11(3):590-601. doi: 10.1208/s12248-009-9135-y. Epub 2009 Aug 18. Review.

7.

Negative feedback regulation of cellular antiviral signaling by RBCK1-mediated degradation of IRF3.

Zhang M, Tian Y, Wang RP, Gao D, Zhang Y, Diao FC, Chen DY, Zhai ZH, Shu HB.

Cell Res. 2008 Nov;18(11):1096-104. doi: 10.1038/cr.2008.277.

PMID:
18711448
8.

Nuclear receptor coactivator 6 mediates the synergistic activation of human cytochrome P-450 2C9 by the constitutive androstane receptor and hepatic nuclear factor-4alpha.

Surapureddi S, Rana R, Reddy JK, Goldstein JA.

Mol Pharmacol. 2008 Sep;74(3):913-23. doi: 10.1124/mol.108.048983. Epub 2008 Jun 13.

9.

Sterol regulatory element binding protein 1 interacts with pregnane X receptor and constitutive androstane receptor and represses their target genes.

Roth A, Looser R, Kaufmann M, Meyer UA.

Pharmacogenet Genomics. 2008 Apr;18(4):325-37. doi: 10.1097/FPC.0b013e3282f706e0.

PMID:
18334917
10.

RBCK1 negatively regulates tumor necrosis factor- and interleukin-1-triggered NF-kappaB activation by targeting TAB2/3 for degradation.

Tian Y, Zhang Y, Zhong B, Wang YY, Diao FC, Wang RP, Zhang M, Chen DY, Zhai ZH, Shu HB.

J Biol Chem. 2007 Jun 8;282(23):16776-82. Epub 2007 Apr 20.

11.

PXR and CAR: nuclear receptors which play a pivotal role in drug disposition and chemical toxicity.

Stanley LA, Horsburgh BC, Ross J, Scheer N, Wolf CR.

Drug Metab Rev. 2006;38(3):515-97. Review.

PMID:
16877263
12.

Identification of potential pharmacological and toxicological targets differentiating structural analogs by a combination of transcriptional profiling and promoter analysis in LS-180 and Caco-2 adenocarcinoma cell lines.

Hartley DP, Dai X, Yabut J, Chu X, Cheng O, Zhang T, He YD, Roberts C, Ulrich R, Evers R, Evans DC.

Pharmacogenet Genomics. 2006 Aug;16(8):579-99.

PMID:
16847427
14.

Regulation and binding of pregnane X receptor by nuclear receptor corepressor silencing mediator of retinoid and thyroid hormone receptors (SMRT).

Johnson DR, Li CW, Chen LY, Ghosh JC, Chen JD.

Mol Pharmacol. 2006 Jan;69(1):99-108. Epub 2005 Oct 11.

15.
16.

Nuclear-cytoplasmic shuttling of a RING-IBR protein RBCK1 and its functional interaction with nuclear body proteins.

Tatematsu K, Yoshimoto N, Koyanagi T, Tokunaga C, Tachibana T, Yoneda Y, Yoshida M, Okajima T, Tanizawa K, Kuroda S.

J Biol Chem. 2005 Jun 17;280(24):22937-44. Epub 2005 Apr 15.

17.

Linking the ubiquitin-proteasome pathway to chromatin remodeling/modification by nuclear receptors.

Kinyamu HK, Chen J, Archer TK.

J Mol Endocrinol. 2005 Apr;34(2):281-97. Review.

PMID:
15821097
18.

Steroid and xenobiotic receptor (SXR), cytochrome P450 3A4 and multidrug resistance gene 1 in human adult and fetal tissues.

Miki Y, Suzuki T, Tazawa C, Blumberg B, Sasano H.

Mol Cell Endocrinol. 2005 Feb 28;231(1-2):75-85. Epub 2005 Jan 23.

PMID:
15713537
19.

The pregnane X receptor regulates gene expression in a ligand- and promoter-selective fashion.

Masuyama H, Suwaki N, Tateishi Y, Nakatsukasa H, Segawa T, Hiramatsu Y.

Mol Endocrinol. 2005 May;19(5):1170-80. Epub 2005 Jan 13.

PMID:
15650019
20.

SEPT5_v2 is a parkin-binding protein.

Choi P, Snyder H, Petrucelli L, Theisler C, Chong M, Zhang Y, Lim K, Chung KK, Kehoe K, D'Adamio L, Lee JM, Cochran E, Bowser R, Dawson TM, Wolozin B.

Brain Res Mol Brain Res. 2003 Oct 7;117(2):179-89.

PMID:
14559152

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