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Preliminary assessment of the efficacy of a T-cell-based influenza vaccine, MVA-NP+M1, in humans.

Lillie PJ, Berthoud TK, Powell TJ, Lambe T, Mullarkey C, Spencer AJ, Hamill M, Peng Y, Blais ME, Duncan CJ, Sheehy SH, Havelock T, Faust SN, Williams RL, Gilbert A, Oxford J, Dong T, Hill AV, Gilbert SC.

Clin Infect Dis. 2012 Jul;55(1):19-25. doi: 10.1093/cid/cis327.


Mortality caused by influenza and respiratory syncytial virus by age group in England and Wales 1999-2010.

Hardelid P, Pebody R, Andrews N.

Influenza Other Respir Viruses. 2013 Jan;7(1):35-45. doi: 10.1111/j.1750-2659.2012.00345.x.


The unmet need in the elderly: how immunosenescence, CMV infection, co-morbidities and frailty are a challenge for the development of more effective influenza vaccines.

McElhaney JE, Zhou X, Talbot HK, Soethout E, Bleackley RC, Granville DJ, Pawelec G.

Vaccine. 2012 Mar 9;30(12):2060-7. doi: 10.1016/j.vaccine.2012.01.015. Review.


T-cell-inducing vaccines - what's the future.

Gilbert SC.

Immunology. 2012 Jan;135(1):19-26. doi: 10.1111/j.1365-2567.2011.03517.x. Review.


Efficacy and effectiveness of influenza vaccines: a systematic review and meta-analysis.

Osterholm MT, Kelley NS, Sommer A, Belongia EA.

Lancet Infect Dis. 2012 Jan;12(1):36-44. doi: 10.1016/S1473-3099(11)70295-X. Review. Erratum in: Lancet Infect Dis. 2012 Sep;12(9):655.


Unbiased molecular analysis of T cell receptor expression using template-switch anchored RT-PCR.

Quigley MF, Almeida JR, Price DA, Douek DC.

Curr Protoc Immunol. 2011 Aug;Chapter 10:Unit10.33. doi: 10.1002/0471142735.im1033s94.


Bias in the αβ T-cell repertoire: implications for disease pathogenesis and vaccination.

Miles JJ, Douek DC, Price DA.

Immunol Cell Biol. 2011 Mar;89(3):375-87. doi: 10.1038/icb.2010.139. Review.


Potent CD8+ T-cell immunogenicity in humans of a novel heterosubtypic influenza A vaccine, MVA-NP+M1.

Berthoud TK, Hamill M, Lillie PJ, Hwenda L, Collins KA, Ewer KJ, Milicic A, Poyntz HC, Lambe T, Fletcher HA, Hill AV, Gilbert SC.

Clin Infect Dis. 2011 Jan 1;52(1):1-7. doi: 10.1093/cid/ciq015.


Influenza vaccines for the future.

Lambert LC, Fauci AS.

N Engl J Med. 2010 Nov 18;363(21):2036-44. doi: 10.1056/NEJMra1002842. Review. No abstract available.


Vaccination of metastatic renal cancer patients with MVA-5T4: a randomized, double-blind, placebo-controlled phase III study.

Amato RJ, Hawkins RE, Kaufman HL, Thompson JA, Tomczak P, Szczylik C, McDonald M, Eastty S, Shingler WH, de Belin J, Goonewardena M, Naylor S, Harrop R.

Clin Cancer Res. 2010 Nov 15;16(22):5539-47. doi: 10.1158/1078-0432.CCR-10-2082.


Granzymes in age-related cardiovascular and pulmonary diseases.

Hendel A, Hiebert PR, Boivin WA, Williams SJ, Granville DJ.

Cell Death Differ. 2010 Apr;17(4):596-606. doi: 10.1038/cdd.2010.5. Review.


Comparing human T cell and NK cell responses in viral-based malaria vaccine trials.

Berthoud TK, Fletcher H, Porter D, Thompson F, Hill AV, Todryk SM.

Vaccine. 2009 Dec 10;28(1):21-7. doi: 10.1016/j.vaccine.2009.09.132.


Immunosenescence and influenza vaccine efficacy.

Sambhara S, McElhaney JE.

Curr Top Microbiol Immunol. 2009;333:413-29. doi: 10.1007/978-3-540-92165-3_20. Review.


Granzyme B: Correlates with protection and enhanced CTL response to influenza vaccination in older adults.

McElhaney JE, Ewen C, Zhou X, Kane KP, Xie D, Hager WD, Barry MB, Kleppinger A, Wang Y, Bleackley RC.

Vaccine. 2009 Apr 21;27(18):2418-25. doi: 10.1016/j.vaccine.2009.01.136.


Mortality benefits of influenza vaccination in elderly people: an ongoing controversy.

Simonsen L, Taylor RJ, Viboud C, Miller MA, Jackson LA.

Lancet Infect Dis. 2007 Oct;7(10):658-66. Review.


Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania major.

Darrah PA, Patel DT, De Luca PM, Lindsay RW, Davey DF, Flynn BJ, Hoff ST, Andersen P, Reed SG, Morris SL, Roederer M, Seder RA.

Nat Med. 2007 Jul;13(7):843-50.


Multiple-cytokine-producing antiviral CD4 T cells are functionally superior to single-cytokine-producing cells.

Kannanganat S, Ibegbu C, Chennareddi L, Robinson HL, Amara RR.

J Virol. 2007 Aug;81(16):8468-76.


Immunosenescence: role and measurement in influenza vaccine response among the elderly.

Targonski PV, Jacobson RM, Poland GA.

Vaccine. 2007 Apr 20;25(16):3066-9. Review.


T cell responses are better correlates of vaccine protection in the elderly.

McElhaney JE, Xie D, Hager WD, Barry MB, Wang Y, Kleppinger A, Ewen C, Kane KP, Bleackley RC.

J Immunol. 2006 May 15;176(10):6333-9.


Avidity for antigen shapes clonal dominance in CD8+ T cell populations specific for persistent DNA viruses.

Price DA, Brenchley JM, Ruff LE, Betts MR, Hill BJ, Roederer M, Koup RA, Migueles SA, Gostick E, Wooldridge L, Sewell AK, Connors M, Douek DC.

J Exp Med. 2005 Nov 21;202(10):1349-61.

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