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Items: 1 to 20 of 62


Down-regulating sphingolipid synthesis increases yeast lifespan.

Huang X, Liu J, Dickson RC.

PLoS Genet. 2012 Feb;8(2):e1002493. doi: 10.1371/journal.pgen.1002493.


Nonlinear fitness landscape of a molecular pathway.

Perfeito L, Ghozzi S, Berg J, Schnetz K, Lässig M.

PLoS Genet. 2011 Jul;7(7):e1002160. doi: 10.1371/journal.pgen.1002160.


Trait variation in yeast is defined by population history.

Warringer J, Zörgö E, Cubillos FA, Zia A, Gjuvsland A, Simpson JT, Forsmark A, Durbin R, Omholt SW, Louis EJ, Liti G, Moses A, Blomberg A.

PLoS Genet. 2011 Jun;7(6):e1002111. doi: 10.1371/journal.pgen.1002111.


Many ceramides.

Hannun YA, Obeid LM.

J Biol Chem. 2011 Aug 12;286(32):27855-62. doi: 10.1074/jbc.R111.254359. Review.


Molecular population genetics and selection in the glycolytic pathway.

Eanes WF.

J Exp Biol. 2011 Jan 15;214(Pt 2):165-71. doi: 10.1242/jeb.046458. Review.


Gene-environment interactions at nucleotide resolution.

Gerke J, Lorenz K, Ramnarine S, Cohen B.

PLoS Genet. 2010 Sep 30;6(9):e1001144. doi: 10.1371/journal.pgen.1001144.


Using synthetic biology to understand the evolution of gene expression.

Bayer TS.

Curr Biol. 2010 Sep 14;20(17):R772-9. doi: 10.1016/j.cub.2010.06.049. Review.


Orm family proteins mediate sphingolipid homeostasis.

Breslow DK, Collins SR, Bodenmiller B, Aebersold R, Simons K, Shevchenko A, Ejsing CS, Weissman JS.

Nature. 2010 Feb 25;463(7284):1048-53. doi: 10.1038/nature08787.


Transient genotype-by-environment interactions following environmental shock provide a source of expression variation for essential genes.

Eng KH, Kvitek DJ, Keles S, Gasch AP.

Genetics. 2010 Feb;184(2):587-93. doi: 10.1534/genetics.109.107268.


The evolution of control and distribution of adaptive mutations in a metabolic pathway.

Wright KM, Rausher MD.

Genetics. 2010 Feb;184(2):483-502. doi: 10.1534/genetics.109.110411.


High-resolution analysis of DNA regulatory elements by synthetic saturation mutagenesis.

Patwardhan RP, Lee C, Litvin O, Young DL, Pe'er D, Shendure J.

Nat Biotechnol. 2009 Dec;27(12):1173-5. doi: 10.1038/nbt.1589.


Validation of reference genes for quantitative expression analysis by real-time RT-PCR in Saccharomyces cerevisiae.

Teste MA, Duquenne M, François JM, Parrou JL.

BMC Mol Biol. 2009 Oct 30;10:99. doi: 10.1186/1471-2199-10-99.


Finding the missing heritability of complex diseases.

Manolio TA, Collins FS, Cox NJ, Goldstein DB, Hindorff LA, Hunter DJ, McCarthy MI, Ramos EM, Cardon LR, Chakravarti A, Cho JH, Guttmacher AE, Kong A, Kruglyak L, Mardis E, Rotimi CN, Slatkin M, Valle D, Whittemore AS, Boehnke M, Clark AG, Eichler EE, Gibson G, Haines JL, Mackay TF, McCarroll SA, Visscher PM.

Nature. 2009 Oct 8;461(7265):747-53. doi: 10.1038/nature08494. Review.


Comparative transcriptomic approach to investigate differences in wine yeast physiology and metabolism during fermentation.

Rossouw D, Olivares-Hernandes R, Nielsen J, Bauer FF.

Appl Environ Microbiol. 2009 Oct;75(20):6600-12. doi: 10.1128/AEM.01251-09.


The repertoire and dynamics of evolutionary adaptations to controlled nutrient-limited environments in yeast.

Gresham D, Desai MM, Tucker CM, Jenq HT, Pai DA, Ward A, DeSevo CG, Botstein D, Dunham MJ.

PLoS Genet. 2008 Dec;4(12):e1000303. doi: 10.1371/journal.pgen.1000303.


Variations in stress sensitivity and genomic expression in diverse S. cerevisiae isolates.

Kvitek DJ, Will JL, Gasch AP.

PLoS Genet. 2008 Oct;4(10):e1000223. doi: 10.1371/journal.pgen.1000223.


The chemical genomic portrait of yeast: uncovering a phenotype for all genes.

Hillenmeyer ME, Fung E, Wildenhain J, Pierce SE, Hoon S, Lee W, Proctor M, St Onge RP, Tyers M, Koller D, Altman RB, Davis RW, Nislow C, Giaever G.

Science. 2008 Apr 18;320(5874):362-5. doi: 10.1126/science.1150021.


Cross-talk at the crossroads of sphingosine-1-phosphate, growth factors, and cytokine signaling.

Lebman DA, Spiegel S.

J Lipid Res. 2008 Jul;49(7):1388-94. doi: 10.1194/jlr.R800008-JLR200. Review.


Principles of bioactive lipid signalling: lessons from sphingolipids.

Hannun YA, Obeid LM.

Nat Rev Mol Cell Biol. 2008 Feb;9(2):139-50. doi: 10.1038/nrm2329. Review.

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