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Application of NMR-based metabonomics suggests a relationship between betaine absorption and elevated creatine plasma concentrations in catheterised sows.

Yde CC, Westerhuis JA, Bertram HC, Bach Knudsen KE.

Br J Nutr. 2012 Jun;107(11):1603-15. doi: 10.1017/S0007114511004909.


Emerging perspectives on essential amino acid metabolism in obesity and the insulin-resistant state.

Adams SH.

Adv Nutr. 2011 Nov;2(6):445-56. doi: 10.3945/an.111.000737. Review.


Nuclear magnetic resonance-based metabolomics enable detection of the effects of a whole grain rye and rye bran diet on the metabolic profile of plasma in prostate cancer patients.

Moazzami AA, Zhang JX, Kamal-Eldin A, Aman P, Hallmans G, Johansson JE, Andersson SO.

J Nutr. 2011 Dec;141(12):2126-32. doi: 10.3945/jn.111.148239.


Postprandial differences in the plasma metabolome of healthy Finnish subjects after intake of a sourdough fermented endosperm rye bread versus white wheat bread.

Bondia-Pons I, Nordlund E, Mattila I, Katina K, Aura AM, Kolehmainen M, Orešič M, Mykkänen H, Poutanen K.

Nutr J. 2011 Oct 19;10:116. doi: 10.1186/1475-2891-10-116.


Changes in the metabolic profile of rat liver after α-tocopherol deficiency as revealed by metabolomics analysis.

Moazzami AA, Andersson R, Kamal-Eldin A.

NMR Biomed. 2011 Jun;24(5):499-505. doi: 10.1002/nbm.1615.


Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.

Wang Z, Klipfell E, Bennett BJ, Koeth R, Levison BS, Dugar B, Feldstein AE, Britt EB, Fu X, Chung YM, Wu Y, Schauer P, Smith JD, Allayee H, Tang WH, DiDonato JA, Lusis AJ, Hazen SL.

Nature. 2011 Apr 7;472(7341):57-63. doi: 10.1038/nature09922.


Metabolite profiles and the risk of developing diabetes.

Wang TJ, Larson MG, Vasan RS, Cheng S, Rhee EP, McCabe E, Lewis GD, Fox CS, Jacques PF, Fernandez C, O'Donnell CJ, Carr SA, Mootha VK, Florez JC, Souza A, Melander O, Clish CB, Gerszten RE.

Nat Med. 2011 Apr;17(4):448-53. doi: 10.1038/nm.2307.


The human serum metabolome.

Psychogios N, Hau DD, Peng J, Guo AC, Mandal R, Bouatra S, Sinelnikov I, Krishnamurthy R, Eisner R, Gautam B, Young N, Xia J, Knox C, Dong E, Huang P, Hollander Z, Pedersen TL, Smith SR, Bamforth F, Greiner R, McManus B, Newman JW, Goodfriend T, Wishart DS.

PLoS One. 2011 Feb 16;6(2):e16957. doi: 10.1371/journal.pone.0016957.


Healthy aspects of the Nordic diet are related to lower total mortality.

Olsen A, Egeberg R, Halkjær J, Christensen J, Overvad K, Tjønneland A.

J Nutr. 2011 Apr 1;141(4):639-44. doi: 10.3945/jn.110.131375.


Metabolomic analysis of plasma metabolites that may mediate effects of rye bread on satiety and weight maintenance in postmenopausal women.

Lankinen M, Schwab U, Seppänen-Laakso T, Mattila I, Juntunen K, Mykkänen H, Poutanen K, Gylling H, Oresic M.

J Nutr. 2011 Jan;141(1):31-6. doi: 10.3945/jn.110.131656.


New hypotheses for the health-protective mechanisms of whole-grain cereals: what is beyond fibre?

Fardet A.

Nutr Res Rev. 2010 Jun;23(1):65-134. doi: 10.1017/S0954422410000041. Review.


Multivariate paired data analysis: multilevel PLSDA versus OPLSDA.

Westerhuis JA, van Velzen EJ, Hoefsloot HC, Smilde AK.

Metabolomics. 2010 Mar;6(1):119-128.


Quantitative measurement of betaine and free choline in plasma, cereals and cereal products by isotope dilution LC-MS/MS.

Bruce SJ, Guy PA, Rezzi S, Ross AB.

J Agric Food Chem. 2010 Feb 24;58(4):2055-61. doi: 10.1021/jf903930k.


Endosperm and whole grain rye breads are characterized by low post-prandial insulin response and a beneficial blood glucose profile.

Rosén LA, Silva LO, Andersson UK, Holm C, Ostman EM, Björck IM.

Nutr J. 2009 Sep 25;8:42. doi: 10.1186/1475-2891-8-42.


Influence of menopause on diabetes and diabetes risk.

Szmuilowicz ED, Stuenkel CA, Seely EW.

Nat Rev Endocrinol. 2009 Oct;5(10):553-8. doi: 10.1038/nrendo.2009.166. Review.


NMR-based metabonomics reveals that plasma betaine increases upon intake of high-fiber rye buns in hypercholesterolemic pigs.

Bertram HC, Malmendal A, Nielsen NC, Straadt IK, Larsen T, Knudsen KE, Laerke HN.

Mol Nutr Food Res. 2009 Aug;53(8):1055-62. doi: 10.1002/mnfr.200800344.


Whole grains and incident hypertension in men.

Flint AJ, Hu FB, Glynn RJ, Jensen MK, Franz M, Sampson L, Rimm EB.

Am J Clin Nutr. 2009 Sep;90(3):493-8. doi: 10.3945/ajcn.2009.27460.


Dietary carbohydrate modification alters serum metabolic profiles in individuals with the metabolic syndrome.

Lankinen M, Schwab U, Gopalacharyulu PV, Seppänen-Laakso T, Yetukuri L, Sysi-Aho M, Kallio P, Suortti T, Laaksonen DE, Gylling H, Poutanen K, Kolehmainen M, Oresic M.

Nutr Metab Cardiovasc Dis. 2010 May;20(4):249-57. doi: 10.1016/j.numecd.2009.04.009.


A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance.

Newgard CB, An J, Bain JR, Muehlbauer MJ, Stevens RD, Lien LF, Haqq AM, Shah SH, Arlotto M, Slentz CA, Rochon J, Gallup D, Ilkayeva O, Wenner BR, Yancy WS Jr, Eisenson H, Musante G, Surwit RS, Millington DS, Butler MD, Svetkey LP.

Cell Metab. 2009 Apr;9(4):311-26. doi: 10.1016/j.cmet.2009.02.002. Erratum in: Cell Metab. 2009 Jun;9(6):565-6.


Effectiveness of whole grain consumption in the prevention of colorectal cancer: meta-analysis of cohort studies.

Haas P, Machado MJ, Anton AA, Silva AS, de Francisco A.

Int J Food Sci Nutr. 2009;60 Suppl 6:1-13.


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