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Items: 1 to 20 of 32

1.

Iron(III) protoporphyrin IX complexes of the antimalarial Cinchona alkaloids quinine and quinidine.

de Villiers KA, Gildenhuys J, le Roex T.

ACS Chem Biol. 2012 Apr 20;7(4):666-71. doi: 10.1021/cb200528z. Epub 2012 Feb 3.

PMID:
22276975
2.

Update on genetic markers of quinine resistance in Plasmodium falciparum.

Okombo J, Ohuma E, Picot S, Nzila A.

Mol Biochem Parasitol. 2011 Jun;177(2):77-82. doi: 10.1016/j.molbiopara.2011.01.012. Epub 2011 Feb 1. Review.

PMID:
21295079
3.

The hydroxyl functionality and a rigid proximal N are required for forming a novel non-covalent quinine-heme complex.

Alumasa JN, Gorka AP, Casabianca LB, Comstock E, de Dios AC, Roepe PD.

J Inorg Biochem. 2011 Mar;105(3):467-75. doi: 10.1016/j.jinorgbio.2010.08.011. Epub 2010 Sep 22.

4.

Antimalarial exposure delays Plasmodium falciparum intra-erythrocytic cycle and drives drug transporter genes expression.

Veiga MI, Ferreira PE, Schmidt BA, Ribacke U, Björkman A, Tichopad A, Gil JP.

PLoS One. 2010 Aug 25;5(8):e12408. doi: 10.1371/journal.pone.0012408.

5.

Artemisinin derivatives versus quinine for cerebral malaria in African children: a systematic review.

Kyu HH, Fernández E.

Bull World Health Organ. 2009 Dec;87(12):896-904. doi: 10.2471/BLT.08.060327. Epub 2009 Jul 30. Review.

6.

Monitoring of in vitro susceptibilities and molecular markers of resistance of Plasmodium falciparum isolates from Thai-Myanmar border to chloroquine, quinine, mefloquine and artesunate.

Chaijaroenkul W, Wisedpanichkij R, Na-Bangchang K.

Acta Trop. 2010 Feb;113(2):190-4. doi: 10.1016/j.actatropica.2009.10.016. Epub 2009 Oct 30.

PMID:
19879850
7.

Interference with hemozoin formation represents an important mechanism of schistosomicidal action of antimalarial quinoline methanols.

Corrêa Soares JB, Menezes D, Vannier-Santos MA, Ferreira-Pereira A, Almeida GT, Venancio TM, Verjovski-Almeida S, Zishiri VK, Kuter D, Hunter R, Egan TJ, Oliveira MF.

PLoS Negl Trop Dis. 2009 Jul 14;3(7):e477. doi: 10.1371/journal.pntd.0000477.

8.

Quinine monotherapy for treating uncomplicated malaria in the era of artemisinin-based combination therapy: an appropriate public health policy?

Yeka A, Achan J, D'Alessandro U, Talisuna AO.

Lancet Infect Dis. 2009 Jul;9(7):448-52. doi: 10.1016/S1473-3099(09)70109-4. Review.

PMID:
19555904
9.

The diamidine DB75 targets the nucleus of Plasmodium falciparum.

Purfield AE, Tidwell RR, Meshnick SR.

Malar J. 2009 May 14;8:104. doi: 10.1186/1475-2875-8-104.

10.

Probing the multifactorial basis of Plasmodium falciparum quinine resistance: evidence for a strain-specific contribution of the sodium-proton exchanger PfNHE.

Nkrumah LJ, Riegelhaupt PM, Moura P, Johnson DJ, Patel J, Hayton K, Ferdig MT, Wellems TE, Akabas MH, Fidock DA.

Mol Biochem Parasitol. 2009 Jun;165(2):122-31. doi: 10.1016/j.molbiopara.2009.01.011. Epub 2009 Jan 30.

11.

Pfmdr1 copy number and arteminisin derivatives combination therapy failure in falciparum malaria in Cambodia.

Lim P, Alker AP, Khim N, Shah NK, Incardona S, Doung S, Yi P, Bouth DM, Bouchier C, Puijalon OM, Meshnick SR, Wongsrichanalai C, Fandeur T, Le Bras J, Ringwald P, Ariey F.

Malar J. 2009 Jan 12;8:11. doi: 10.1186/1475-2875-8-11.

12.

The role of neutral lipid nanospheres in Plasmodium falciparum haem crystallization.

Pisciotta JM, Coppens I, Tripathi AK, Scholl PF, Shuman J, Bajad S, Shulaev V, Sullivan DJ Jr.

Biochem J. 2007 Feb 15;402(1):197-204.

13.

Decreasing pfmdr1 copy number in plasmodium falciparum malaria heightens susceptibility to mefloquine, lumefantrine, halofantrine, quinine, and artemisinin.

Sidhu AB, Uhlemann AC, Valderramos SG, Valderramos JC, Krishna S, Fidock DA.

J Infect Dis. 2006 Aug 15;194(4):528-35. Epub 2006 Jul 11.

14.

Molecular and pharmacological determinants of the therapeutic response to artemether-lumefantrine in multidrug-resistant Plasmodium falciparum malaria.

Price RN, Uhlemann AC, van Vugt M, Brockman A, Hutagalung R, Nair S, Nash D, Singhasivanon P, Anderson TJ, Krishna S, White NJ, Nosten F.

Clin Infect Dis. 2006 Jun 1;42(11):1570-7. Epub 2006 Apr 26.

15.
16.

Quinoline antimalarials decrease the rate of beta-hematin formation.

Egan TJ, Ncokazi KK.

J Inorg Biochem. 2005 Jul;99(7):1532-9.

PMID:
15927260
17.

Are transporter genes other than the chloroquine resistance locus (pfcrt) and multidrug resistance gene (pfmdr) associated with antimalarial drug resistance?

Anderson TJ, Nair S, Qin H, Singlam S, Brockman A, Paiphun L, Nosten F.

Antimicrob Agents Chemother. 2005 Jun;49(6):2180-8. Erratum in: Antimicrob Agents Chemother. 2005 Sep;49(9):3990.

18.

Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy number.

Price RN, Uhlemann AC, Brockman A, McGready R, Ashley E, Phaipun L, Patel R, Laing K, Looareesuwan S, White NJ, Nosten F, Krishna S.

Lancet. 2004 Jul 31-Aug 6;364(9432):438-447. doi: 10.1016/S0140-6736(04)16767-6.

19.

Multiple transporters associated with malaria parasite responses to chloroquine and quinine.

Mu J, Ferdig MT, Feng X, Joy DA, Duan J, Furuya T, Subramanian G, Aravind L, Cooper RA, Wootton JC, Xiong M, Su XZ.

Mol Microbiol. 2003 Aug;49(4):977-89.

20.

Resistance to antimalarials in Southeast Asia and genetic polymorphisms in pfmdr1.

Pickard AL, Wongsrichanalai C, Purfield A, Kamwendo D, Emery K, Zalewski C, Kawamoto F, Miller RS, Meshnick SR.

Antimicrob Agents Chemother. 2003 Aug;47(8):2418-23.

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